A Call for Objective Dose Selection to Increase Success in Pediatric Clinical Trials: A Perspective From NICHD and NIMH Program Staff von Giacoia, George, Grabb, Margaret C., Pawlyk, Aaron C., Ren, Zhaoxia, Samedy‐Bates, Lesly, Taylor‐Zapata, Perdita

Volltext

Development of a Pediatric Adverse Events Terminology von Gipson, Debbie S, Kirkendall, Eric S, Gumbs-Petty, Brenda, Quinn, Theresa, Steen, A, Hicks, Amanda, McMahon, Ann, Nicholas, Savian, Zhao-Wong, Anna, Taylor-Zapata, Perdita, Turner, Mark, Herreshoff, Emily, Jones, Charlotte, Davis, Jonathan M, Haber, Margaret, Hirschfeld, Steven

Volltext

Physiologically‐Based Pharmacokinetic Modeling Characterizes the CYP3A‐Mediated Drug‐Drug Interaction Between Fluconazole and Sildenafil in Infants von Salerno, Sara N., Edginton, Andrea, Gerhart, Jacqueline G., Laughon, Matthew M., Ambalavanan, Namasivayam, Sokol, Gregory M., Hornik, Chi D., Stewart, Dan, Mills, Mary, Martz, Karen, Gonzalez, Daniel, Benjamin Jr, Daniel K, Hornik, Christoph, Zimmerman, Kanecia, Kennel, Phyllis, Beci, Rose, Hornik, Chi Dang, Kearns, Gregory L, Laughon, Matthew, Paul, Ian M, Sullivan, Janice, Wade, Kelly, Delmore, Paula, Kennedy, Eunice, Taylor‐Zapata, Perdita, Lee, June, Anand, Ravinder, Sharma, Gaurav, Simone, Gina, Kaneshige, Kim, Taylor, Lawrence, Green, Thomas, Lurie, Robert H., Ambalavanan, Namasivayam, McNair, Tara E, Phillips, Vivien, Atz, Andrew, Choudhary, Kalyan Janakiram, Sokol, Gregory M, Gunn, Susan, Herron, Dianne, Smiley, Lucy, Hornik, Chi D, Michael Cotten, C., Andrews, Lacey, Stewart, Dan, Sullivan, Janice, Michael, Andrew, Mundakel, Gratias, Limbu, Subhatra, Poindexter, Brenda, Wuertz, Sandra

Volltext

Use of Real‐World Data and Physiologically‐Based Pharmacokinetic Modeling to Characterize Enoxaparin Disposition in Children With Obesity von Gerhart, Jacqueline G., Carreño, Fernando O., Loop, Matthew Shane, Lee, Craig R., Edginton, Andrea N., Sinha, Jaydeep, Kumar, Karan R., Kirkpatrick, Carl M., Hornik, Christoph P., Gonzalez, Daniel, Benjamin Jr, Daniel K., Zimmerman, Kanecia, Kennel, Phyllis, Beci, Rose, Hornik, Chi Dang, Kearns, Gregory L., Laughon, Matthew, Paul, Ian M., Sullivan, Janice, Wade, Kelly, Delmore, Paula, Taylor‐Zapata, Perdita, Lee, June, Green, Thomas, Atz, Andrew, Lenert, Leslie, Clark, John, Chundru, Kalyan, Bendel, Catherine, Harvey, Brian, Grillo, Sonya, Chan, Francis, Fan, Stephanie, Linda, Lorma, Downes, Kevin, Grundmeier, Robert, Ramos, Mark, O’Connor, Shawn, Fogel, Benjamin, Gipson, Debbie, Attala, Samara, Eickstadt, Richard, Kaleba, Erin, Liamini, Don, Estill, Jamie, Jared, Jeremy, Bow, Peter, Laughon, Matt, Talbert, Jennifer, Clark, Cindy, Miller, Michael, Muller, William, Smith, Michael, Sullivan, Janice, Heilman, Steve, Singh, KP, Vuyyuri, Satish, Schwitters, Jeff, Stone, Don

Volltext

Antihypertensive Drug Use By Children: Are the Drugs Labeled and Indicated? von Welch, W. Pete, Yang, Wenya, Taylor‐Zapata, Perdita, Flynn, Joseph T.

Volltext

Expediting Drug Development for Pediatric Inflammatory Bowel Disease: A Discussion With Stakeholders von Mulberg, Andrew E., Bousvaros, Athos, Colletti, Richard, Hyams, Jeffrey, Lee, Kerry Jo, Musaus, Joachim, Robinson, Anne M., Rosh, Joel, Saeed, Shehzad, Taylor‐Zapata, Perdita, Zuckerman, Eric, Winter, Harland S.

Volltext

Use of physiologically‐based pharmacokinetic modeling to inform dosing of the opioid analgesics fentanyl and methadone in children with obesity von Gerhart, Jacqueline G., Carreño, Fernando O., Ford, Jennifer L., Edginton, Andrea N., Perrin, Eliana M., Watt, Kevin M., Muller, William J., Atz, Andrew M., Al‐Uzri, Amira, Delmore, Paula, Gonzalez, Daniel, Benjamin, Daniel K., Hornik, Christoph, Zimmerman, Kanecia, Kennel, Phyllis, Beci, Rose, Dang Hornik, Chi, Kearns, Gregory L., Laughon, Matthew, Paul, Ian M., Sullivan, Janice, Wade, Kelly, Delmore, Paula, Taylor‐Zapata, Perdita, Lee, June, Anand, Ravinder, Sharma, Gaurav, Simone, Gina, Kaneshige, Kim, Taylor, Lawrence, Al‐Uzri, Amira, Hornik, Chi, Sokol, Gregory, Speicher, David, Sullivan, Janice, Mourani, Peter, Mendley, Susan, Meyer, Marisa, Atkins, Robert, Flynn, Joseph, Vaughns, Janelle, Sherwin, Catherine, Delmore, Paula, Goldstein, Stuart, Rathore, Mobeen, Melloni, Chiara, Muller, William, Delmore, Paula, Tremoulet, Adriana, James, Laura, Mendley, Susan, Blackford, Martha, Atz, Andrew, Adu‐Darko, Michelle, Mourani, Peter, Watt, Kevin, Hornik, Chi, Al‐Uzri, Amira, Sullivan, Janice, Laughon, Matthew, Brian Smith, P., Watt, Kevin, Cheifetz, Ira, Atz, Andrew, Bhatt‐Mehta, Varsha, Fernandez, Allison, Lowry, Jennifer

Volltext

Eunice Kennedy Shriver National Institute of Child Health and Human Development Pediatrics Formulation Initiative: Proceedings from the Second Workshop on Pediatric Formulations von Giacoia, George P., MD, Taylor-Zapata, Perdita, MD, Zajicek, Anne, MD, PharmD

Volltext

First-Dose Pharmacokinetics of Lithium Carbonate in Children and Adolescents von FINDLING, Robert L, LANDERSDORFER, Cornelia B, FABER, Jon, TAYLOR-ZAPATA, Perdita, JUSKO, William J, KAFANTARIS, Vivian, PAVULURI, Mani, MCNAMARA, Nora K, MCCLELLAN, Jon, FRAZIER, Jean A, SIKICH, Linmarie, KOWATCH, Robert, LINGLER, Jacqui

Volltext

Population Pharmacokinetics and Exploratory Exposure‐Response Relationships of Diazepam in Children Treated for Status Epilepticus von Ku, Lawrence C., Hornik, Christoph P., Beechinor, Ryan J., Chamberlain, James M., Guptill, Jeffrey T., Harper, Barrie, Capparelli, Edmund V., Martz, Karen, Anand, Ravinder, Cohen‐Wolkowiez, Michael, Gonzalez, Daniel, Furda, Gary, Benjamin, Danny, Kearns, Gregory L., Paul, Ian M., Sullivan, Jan, Hornik, Christoph P., Wade, Kelly, Siegel, David, Taylor‐Zapata, Perdita, Zajicek, Anne, Ren, Zhaoxia, Tsilou, Ekaterini, Pagan, Alice, Simone, Gina, Ku, Lawrence, Mills, Mary, Watt, Kevin

Volltext

Physician Bias and Clinical Trial Participation in Underrepresented Populations von Popkin, Ronna, Taylor-Zapata, Perdita, Bianchi, Diana W

Volltext

Eunice Kennedy Shriver National Institute of Child Health and Human Development Pediatric Formulation Initiative: Selected reports from working groups von Giacoia, George P., MD, Taylor-Zapata, Perdita, MD, Mattison, Donald, MD

Volltext

Development and Evaluation of a Virtual Population of Children with Obesity for Physiologically Based Pharmacokinetic Modeling von Gerhart, Jacqueline G., Carreño, Fernando O., Edginton, Andrea N., Sinha, Jaydeep, Perrin, Eliana M., Kumar, Karan R., Rikhi, Aruna, Hornik, Christoph P., Harris, Vincent, Ganguly, Samit, Cohen-Wolkowiez, Michael, Gonzalez, Daniel

Volltext

Lithium in the Acute Treatment of Bipolar I Disorder: A Double-Blind, Placebo-Controlled Study von Findling, Robert L, Robb, Adelaide, McNamara, Nora K, Pavuluri, Mani N, Kafantaris, Vivian, Scheffer, Russell, Frazier, Jean A, Rynn, Moira, DelBello, Melissa, Kowatch, Robert A, Rowles, Brieana M, Lingler, Jacqui, Martz, Karen, Anand, Ravinder, Clemons, Traci E, Taylor-Zapata, Perdita

Volltext

The Collaborative Lithium Trials (CoLT): specific aims, methods, and implementation von Findling, Robert L, Frazier, Jean A, Kafantaris, Vivian, Kowatch, Robert, McClellan, Jon, Pavuluri, Mani, Sikich, Linmarie, Hlastala, Stefanie, Hooper, Stephen R, Demeter, Christine A, Bedoya, Denise, Brownstein, Bernard, Taylor-Zapata, Perdita

Volltext

Lithium for the Maintenance Treatment of Bipolar I Disorder: A Double-Blind, Placebo-Controlled Discontinuation Study von Findling, Robert L, McNamara, Nora K, Pavuluri, Mani, Frazier, Jean A, Rynn, Moira, Scheffer, Russell, Kafantaris, Vivian, Robb, Adelaide, DelBello, Melissa, Kowatch, Robert A, Rowles, Brieana M, Lingler, Jacqui, Zhao, Jian, Clemons, Traci, Martz, Karen, Anand, Ravinder, Taylor-Zapata, Perdita

Volltext

Physiologically Based Pharmacokinetic Modeling of Meropenem in Preterm and Term Infants von Ganguly, Samit, Edginton, Andrea N., Gerhart, Jacqueline G., Cohen-Wolkowiez, Michael, Greenberg, Rachel G., Gonzalez, Daniel

Volltext

Anaerobic antimicrobial therapy after necrotizing enterocolitis in VLBW infants von Autmizguine, Julie, Hornik, Christoph P, Benjamin, Jr, Daniel K, Laughon, Matthew M, Clark, Reese H, Cotten, C Michael, Cohen-Wolkowiez, Michael, Benjamin, Daniel K, Smith, P Brian

Volltext

Research Gaps in Primary Pediatric Hypertension von Taylor-Zapata, Perdita, Baker-Smith, Carissa M, Burckart, Gilbert, Daniels, Stephen R, Flynn, Joseph T, Giacoia, George, Green, Dionna, Kelly, Aaron S, Khurana, Mona, Li, Jennifer S, Pratt, Charlotte, Urbina, Elaine M, Zajicek, Anne

Volltext

Comparative Effectiveness of Surfactant Preparations in Premature Infants von Trembath, Andrea, MD, MPH, Hornik, Christoph P., MD, MPH, Clark, Reese, MD, Smith, P. Brian, MD, MPH, MHS, Daniels, Julie, PhD, MPH, Laughon, Matthew, MD, MPH

Volltext