Medulloblastoma: From Myth to Molecular von Ramaswamy, Vijay, Taylor, Michael D

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The U1 spliceosomal RNA is recurrently mutated in multiple cancers von Shuai, Shimin, Suzuki, Hiromichi, Diaz-Navarro, Ander, Nadeu, Ferran, Kumar, Sachin A., Gutierrez-Fernandez, Ana, Delgado, Julio, Pinyol, Magda, López-Otín, Carlos, Puente, Xose S., Taylor, Michael D., Campo, Elías, Stein, Lincoln D.

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Medulloblastoma Comprises Four Distinct Molecular Variants von NORTHCOTT, Paul A, KORSHUNOV, Andrey, RUTKA, James T, PFISTER, Stefan, TAYLOR, Michael D, WITT, Hendrik, HIELSCHER, Thomas, EBERHART, Charles G, MACK, Stephen, BOUFFET, Eric, CLIFFORD, Steven C, HAWKINS, Cynthia E, FRENCH, Pim

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Risk stratification of childhood medulloblastoma in the molecular era: the current consensus von Ramaswamy, Vijay, Remke, Marc, Bouffet, Eric, Bailey, Simon, Clifford, Steven C., Doz, Francois, Kool, Marcel, Dufour, Christelle, Vassal, Gilles, Milde, Till, Witt, Olaf, von Hoff, Katja, Pietsch, Torsten, Northcott, Paul A., Gajjar, Amar, Robinson, Giles W., Padovani, Laetitia, André, Nicolas, Massimino, Maura, Pizer, Barry, Packer, Roger, Rutkowski, Stefan, Pfister, Stefan M., Taylor, Michael D., Pomeroy, Scott L.

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Second-generation molecular subgrouping of medulloblastoma: an international meta-analysis of Group 3 and Group 4 subtypes von Sharma, Tanvi, Schwalbe, Edward C., Williamson, Daniel, Sill, Martin, Hovestadt, Volker, Mynarek, Martin, Rutkowski, Stefan, Robinson, Giles W., Gajjar, Amar, Cavalli, Florence, Ramaswamy, Vijay, Taylor, Michael D., Lindsey, Janet C., Hill, Rebecca M., Jäger, Natalie, Korshunov, Andrey, Hicks, Debbie, Bailey, Simon, Kool, Marcel, Chavez, Lukas, Northcott, Paul A., Pfister, Stefan M., Clifford, Steven C.

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scRNA-seq in medulloblastoma shows cellular heterogeneity and lineage expansion support resistance to SHH inhibitor therapy von Ocasio, Jennifer Karin, Babcock, Benjamin, Malawsky, Daniel, Weir, Seth J., Loo, Lipin, Simon, Jeremy M., Zylka, Mark J., Hwang, Duhyeong, Dismuke, Taylor, Sokolsky, Marina, Rosen, Elias P., Vibhakar, Rajeev, Zhang, Jiao, Saulnier, Olivier, Vladoiu, Maria, El-Hamamy, Ibrahim, Stein, Lincoln D., Taylor, Michael D., Smith, Kyle S., Northcott, Paul A., Colaneri, Alejandro, Wilhelmsen, Kirk, Gershon, Timothy R.

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HDAC and PI3K Antagonists Cooperate to Inhibit Growth of MYC-Driven Medulloblastoma von Pei, Yanxin, Liu, Kun-Wei, Wang, Jun, Garancher, Alexandra, Tao, Ran, Esparza, Lourdes A., Maier, Donna L., Udaka, Yoko T., Murad, Najiba, Morrissy, Sorana, Seker-Cin, Huriye, Brabetz, Sebastian, Qi, Lin, Kogiso, Mari, Schubert, Simone, Olson, James M., Cho, Yoon-Jae, Li, Xiao-Nan, Crawford, John R., Levy, Michael L., Kool, Marcel, Pfister, Stefan M., Taylor, Michael D., Wechsler-Reya, Robert J.

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DeepVelo: deep learning extends RNA velocity to multi-lineage systems with cell-specific kinetics von Cui, Haotian, Maan, Hassaan, Vladoiu, Maria C, Zhang, Jiao, Taylor, Michael D, Wang, Bo

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Association between diffuse myocardial fibrosis and diastolic dysfunction in sickle cell anemia von Niss, Omar, Fleck, Robert, Makue, Fowe, Alsaied, Tarek, Desai, Payal, Towbin, Jeffrey A., Malik, Punam, Taylor, Michael D., Quinn, Charles T.

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Accelerated Cine Cardiac MRI Using Deep Learning‐Based Reconstruction: A Systematic Evaluation von Pednekar, Amol, Kocaoglu, Murat, Wang, Hui, Tanimoto, Aki, Tkach, Jean A., Lang, Sean, Taylor, Michael D.

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Distinct Neural Stem Cell Populations Give Rise to Disparate Brain Tumors in Response to N-MYC von Swartling, Fredrik J., Savov, Vasil, Persson, Anders I., Chen, Justin, Hackett, Christopher S., Northcott, Paul A., Grimmer, Matthew R., Lau, Jasmine, Chesler, Louis, Perry, Arie, Phillips, Joanna J., Taylor, Michael D., Weiss, William A.

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Eplerenone for early cardiomyopathy in Duchenne muscular dystrophy: a randomised, double-blind, placebo-controlled trial von Raman, Subha V, Dr, Hor, Kan N, MD, Mazur, Wojciech, MD, Halnon, Nancy J, MD, Kissel, John T, MD, He, Xin, PhD, Tran, Tam, BS, Smart, Suzanne, BS, McCarthy, Beth, RT, Taylor, Michael D, MD, Jefferies, John L, MD, Rafael-Fortney, Jill A, PhD, Lowe, Jeovanna, MS, Roble, Sharon L, MD, Cripe, Linda H, MD

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Quiescent Sox2+ Cells Drive Hierarchical Growth and Relapse in Sonic Hedgehog Subgroup Medulloblastoma von Vanner, Robert J., Remke, Marc, Gallo, Marco, Selvadurai, Hayden J., Coutinho, Fiona, Lee, Lilian, Kushida, Michelle, Head, Renee, Morrissy, Sorana, Zhu, Xueming, Aviv, Tzvi, Voisin, Veronique, Clarke, Ian D., Li, Yisu, Mungall, Andrew J., Moore, Richard A., Ma, Yussanne, Jones, Steven J.M., Marra, Marco A., Malkin, David, Northcott, Paul A., Kool, Marcel, Pfister, Stefan M., Bader, Gary, Hochedlinger, Konrad, Korshunov, Andrey, Taylor, Michael D., Dirks, Peter B.

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The eEF2 Kinase Confers Resistance to Nutrient Deprivation by Blocking Translation Elongation von Leprivier, Gabriel, Remke, Marc, Rotblat, Barak, Dubuc, Adrian, Mateo, Abigail-Rachele F., Kool, Marcel, Agnihotri, Sameer, El-Naggar, Amal, Yu, Bin, Prakash Somasekharan, Syam, Faubert, Brandon, Bridon, Gaëlle, Tognon, Cristina E., Mathers, Joan, Thomas, Ryan, Li, Amy, Barokas, Adi, Kwok, Brian, Bowden, Mary, Smith, Stephanie, Wu, Xiaochong, Korshunov, Andrey, Hielscher, Thomas, Northcott, Paul A., Galpin, Jason D., Ahern, Christopher A., Wang, Ye, McCabe, Martin G., Collins, V. Peter, Jones, Russell G., Pollak, Michael, Delattre, Olivier, Gleave, Martin E., Jan, Eric, Pfister, Stefan M., Proud, Christopher G., Derry, W. Brent, Taylor, Michael D., Sorensen, Poul H.

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Breath-hold and free-breathing quantitative assessment of biventricular volume and function using compressed SENSE: a clinical validation in children and young adults von Kocaoglu, Murat, Pednekar, Amol S, Wang, Hui, Alsaied, Tarek, Taylor, Michael D, Rattan, Mantosh S

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Concise Review of Nickel Human Health Toxicology and Ecotoxicology von Buxton, Samuel, Garman, Emily, Heim, Katherine E., Lyons-Darden, Tara, Schlekat, Christian E., Taylor, Michael D., Oller, Adriana R.

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The molecular biology of medulloblastoma metastasis von Van Ommeren, Randy, Garzia, Livia, Holgado, Borja L., Ramaswamy, Vijay, Taylor, Michael D.

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The Transition from Quiescent to Activated States in Human Hematopoietic Stem Cells Is Governed by Dynamic 3D Genome Reorganization von Takayama, Naoya, Murison, Alex, Takayanagi, Shin-ichiro, Arlidge, Christopher, Zhou, Stanley, Garcia-Prat, Laura, Chan-Seng-Yue, Michelle, Zandi, Sasan, Gan, Olga I., Boutzen, Héléna, Kaufmann, Kerstin B., Trotman-Grant, Aaron, Schoof, Erwin, Kron, Ken, Díaz, Noelia, Lee, John J.Y., Medina, Tiago, De Carvalho, Daniel D., Taylor, Michael D., Vaquerizas, Juan M., Xie, Stephanie Z., Dick, John E., Lupien, Mathieu

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YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation von Fernandez-L, Africa, Northcott, Paul A, Dalton, James, Fraga, Charles, Ellison, David, Angers, Stephane, Taylor, Michael D, Kenney, Anna Marie

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MicroRNA-199b-5p impairs cancer stem cells through negative regulation of HES1 in medulloblastoma von Garzia, Livia, Andolfo, Immacolata, Cusanelli, Emilio, Marino, Natascia, Petrosino, Giuseppe, De Martino, Daniela, Esposito, Veronica, Galeone, Aldo, Navas, Luigi, Esposito, Silvia, Gargiulo, Sara, Fattet, Sarah, Donofrio, Vittoria, Cinalli, Giuseppe, Brunetti, Arturo, Vecchio, Luigi Del, Northcott, Paul A, Delattre, Olivier, Taylor, Michael D, Iolascon, Achille, Zollo, Massimo

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