Impact of GPCR Structures on Drug Discovery von Congreve, Miles, de Graaf, Chris, Swain, Nigel A., Tate, Christopher G.

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Cryo-Electron Microscopy: Moving Beyond X-Ray Crystal Structures for Drug Receptors and Drug Development von García-Nafría, Javier, Tate, Christopher G

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Structure of the adenosine A2A receptor bound to an engineered G protein von Carpenter, Byron, Nehmé, Rony, Warne, Tony, Leslie, Andrew G. W., Tate, Christopher G.

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Who makes acquisitions? CEO overconfidence and the market's reaction von Malmendier, Ulrike, Tate, Geoffrey

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Mini G protein probes for active G protein–coupled receptors (GPCRs) in live cells von Wan, Qingwen, Okashah, Najeah, Inoue, Asuka, Nehmé, Rony, Carpenter, Byron, Tate, Christopher G., Lambert, Nevin A.

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Cryo-EM structure of the serotonin 5-HT1B receptor coupled to heterotrimeric Go von García-Nafría, Javier, Nehmé, Rony, Edwards, Patricia C., Tate, Christopher G.

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Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation von Lebon, Guillaume, Warne, Tony, Edwards, Patricia C., Bennett, Kirstie, Langmead, Christopher J., Leslie, Andrew G. W., Tate, Christopher G.

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Active state structures of G protein-coupled receptors highlight the similarities and differences in the G protein and arrestin coupling interfaces von Carpenter, Byron, Tate, Christopher G

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Crystal Structures of a Stabilized β1-Adrenoceptor Bound to the Biased Agonists Bucindolol and Carvedilol von Warne, Tony, Edwards, Patricia C., Leslie, Andrew G.W., Tate, Christopher G.

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Mini-G proteins: Novel tools for studying GPCRs in their active conformation von Nehmé, Rony, Carpenter, Byron, Singhal, Ankita, Strege, Annette, Edwards, Patricia C, White, Courtney F, Du, Haijuan, Grisshammer, Reinhard, Tate, Christopher G

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How Can Mutations Thermostabilize G-Protein-Coupled Receptors? von Vaidehi, Nagarajan, Grisshammer, Reinhard, Tate, Christopher G

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Molecular basis for high-affinity agonist binding in GPCRs von Warne, Tony, Edwards, Patricia C, Doré, Andrew S, Leslie, Andrew G W, Tate, Christopher G

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Diverse activation pathways in class A GPCRs converge near the G-protein-coupling region von Venkatakrishnan, A. J., Deupi, Xavier, Lebon, Guillaume, Heydenreich, Franziska M., Flock, Tilman, Miljus, Tamara, Balaji, Santhanam, Bouvier, Michel, Veprintsev, Dmitry B., Tate, Christopher G., Schertler, Gebhard F. X., Babu, M. Madan

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PtdIns(4,5)P2 stabilizes active states of GPCRs and enhances selectivity of G-protein coupling von Yen, Hsin-Yung, Hoi, Kin Kuan, Liko, Idlir, Hedger, George, Horrell, Michael R., Song, Wanling, Wu, Di, Heine, Philipp, Warne, Tony, Lee, Yang, Carpenter, Byron, Plückthun, Andreas, Tate, Christopher G., Sansom, Mark S. P., Robinson, Carol V.

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The structural basis for agonist and partial agonist action on a β1-adrenergic receptor von Warne, Tony, Moukhametzianov, Rouslan, Baker, Jillian G., Nehmé, Rony, Edwards, Patricia C., Leslie, Andrew G. W., Schertler, Gebhard F. X., Tate, Christopher G.

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Structure of the agonist-bound neurotensin receptor von White, Jim F., Noinaj, Nicholas, Shibata, Yoko, Love, James, Kloss, Brian, Xu, Feng, Gvozdenovic-Jeremic, Jelena, Shah, Priyanka, Shiloach, Joseph, Tate, Christopher G., Grisshammer, Reinhard

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Structure of a β1-adrenergic G-protein-coupled receptor von Warne, Tony, Serrano-Vega, Maria J., Baker, Jillian G., Moukhametzianov, Rouslan, Edwards, Patricia C., Henderson, Richard, Leslie, Andrew G. W., Tate, Christopher G., Schertler, Gebhard F. X.

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Structure of the class D GPCR Ste2 dimer coupled to two G proteins von Velazhahan, Vaithish, Ma, Ning, Pándy-Szekeres, Gáspár, Kooistra, Albert J., Lee, Yang, Gloriam, David E., Vaidehi, Nagarajan, Tate, Christopher G.

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The 2.1 Å resolution structure of cyanopindolol-bound β1-adrenoceptor identifies an intramembrane Na+ ion that stabilises the ligand-free receptor von Miller-Gallacher, Jennifer L, Nehmé, Rony, Warne, Tony, Edwards, Patricia C, Schertler, Gebhard F X, Leslie, Andrew G W, Tate, Christopher G

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Traumatic Spinal Cord Injury and Risk of Early and Late Onset Alzheimer’s Disease and Related Dementia: Large Longitudinal Study von Mahmoudi, Elham, Lin, Paul, Peterson, Mark D., Meade, Michelle A., Tate, Denise G., Kamdar, Neil

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