Preclinical translational platform of neuroinflammatory disease biology relevant to neurodegenerative disease von Larson, Kelley C, Martens, Lauren H, Marconi, Michael, Dejesus, Christopher, Bruhn, Suzanne, Miller, Thomas A, Tate, Barbara, Levenson, Jonathan M

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Phosphodiesterase 5A Inhibitors Improve Functional Recovery after Stroke in Rats: Optimized Dosing Regimen with Implications for Mechanism von Menniti, Frank S, Ren, JingMei, Coskran, Timothy M, Liu, Jing, Morton, Daniel, Sietsma, Dana K, Som, Angel, Stephenson, Diane T, Tate, Barbara A, Finklestein, Seth P

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Personalized medicine for pathological circadian dysfunctions von Skelton, Rachel L, Kornhauser, Jon M, Tate, Barbara A

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Pathologic Evaluation of the Human Suprachiasmatic Nucleus in Severe Dementia von Stopa, Edward G, Volicer, Ladislav, Kuo-Leblanc, Victoria, Harper, David, Lathi, Devayani, Tate, Barbara, Satlin, Andrew

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An Approach to Studying Circadian Rhythms of Adolescent Humans von Carskadon, Mary A., Acebo, Christine, Richardson, Gary S., Tate, Barbara A., Seifer, Ronald

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Phase Response Curve to Melatonin in a Putatively Diurnal Rodent, Octodon degus von Morris, Luc G., Tate, Barbara A.

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Optimization of a Natural Product-Based Class of γ‑Secretase Modulators von Hubbs, Jed L, Fuller, Nathan O, Austin, Wesley F, Shen, Ruichao, Creaser, Steffen P, McKee, Timothy D, Loureiro, Robyn M. B, Tate, Barbara, Xia, Weiming, Ives, Jeffrey, Bronk, Brian S

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Pharmacodynamics and pharmacokinetics of the gamma-secretase inhibitor PF-3084014 von Lanz, Thomas A, Wood, Kathleen M, Richter, Karl E G, Nolan, Charles E, Becker, Stacey L, Pozdnyakov, Nikolay, Martin, Barbara-Anne, Du, Ping, Oborski, Christine E, Wood, Douglas E, Brown, Tracy M, Finley, James E, Sokolowski, Sharon A, Hicks, Carol D, Coffman, Karen J, Geoghegan, Kieran F, Brodney, Michael A, Liston, Dane, Tate, Barbara

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An improved cell-based method for determining the γ-secretase enzyme activity against both Notch and APP substrates von McKee, Timothy D., Loureiro, Robyn M.B., Dumin, Jo Ann, Zarayskiy, Vladislav, Tate, Barbara

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Minimization of drug–drug interaction risk and candidate selection in a natural product-based class of gamma-secretase modulators von Hubbs, Jed L., Fuller, Nathan O., Austin, Wesley F., Shen, Ruichao, Ma, Jianguo, Gong, Zhen, Li, Jian, McKee, Timothy D., Loureiro, Robyn M.B., Tate, Barbara, Dumin, Jo Ann, Ives, Jeffrey, Bronk, Brian S.

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Entrainment of Aged, Dysrhythmic Rats to a Restricted Feeding Schedule von WALCOTT, ELISABETH C, TATE, BARBARA A

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Design, synthesis, and in vivo characterization of a novel series of tetralin amino imidazoles as γ-secretase inhibitors: Discovery of PF-3084014 von Brodney, Michael A., Auperin, David D., Becker, Stacey L., Bronk, Brian S., Brown, Tracy M., Coffman, Karen J., Finley, James E., Hicks, Carol D., Karmilowicz, Michael J., Lanz, Thomas A., Liston, Dane, Liu, Xingrong, Martin, Barbara-Anne, Nelson, Robert B., Nolan, Charles E., Oborski, Christine E., Parker, Christine P., Richter, Karl E.G., Pozdnyakov, Nikolay, Sahagan, Barbara G., Schachter, Joel B., Sokolowski, Sharon A., Tate, Barbara, Wood, Douglas E., Wood, Kathleen M., Van Deusen, Jeffrey W., Zhang, Lei

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Efficacy of SPI-1865, a novel gamma-secretase modulator, in multiple rodent models von Loureiro, Robyn M, Dumin, Jo Ann, McKee, Timothy D, Austin, Wesley F, Fuller, Nathan O, Hubbs, Jed L, Shen, Ruichao, Jonker, Jeff, Ives, Jeff, Bronk, Brian S, Tate, Barbara

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Gamma—secretase modulators do not show a potency shift in high expressing model systems von Bronk, Brian, Tate, Barbara, Loureiro, Robyn, Austin, Wesley, Creaser, Steffen, Fuller, Nathan, Hubbs, Jed

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Pharmacokinetic properties of a Satori gamma-secretase modulator, SPI-1865, in multiple animal model systems von Bronk, Brian, McKee, Timothy, Loureiro, Robyn, Dumin, Jo Ann, Zarayskiy, Vladislav, Austin, Wesley, Fuller, Nathan, Hubbs, Jed, Shen, Ruichao, Pearson, Paul, Tate, Barbara

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P4‐199: Pharmacokinetic properties of a Satori gamma‐secretase modulator, SPI‐1865, in multiple animal model systems von Bronk, Brian, McKee, Timothy, Loureiro, Robyn, Dumin, Jo Ann, Zarayskiy, Vladislav, Austin, Wesley, Fuller, Nathan, Hubbs, Jed, Shen, Ruichao, Pearson, Paul, Tate, Barbara

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Classification of γ-secretase modulators and their effect on pharmacological profiles of amyloid β peptides von Xia, Weiming, McKee, Timothy, Loureiro, Robyn, Austin, Wesley, Bronk, Brian, Creaser, Steffen, Fuller, Nathan, Hubbs, Jed, Pojasek, Kevin, Tate, Barbara

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P2‐513: Classification of γ‐secretase modulators and their effect on pharmacological profiles of amyloid β peptides von Xia, Weiming, McKee, Timothy, Loureiro, Robyn, Austin, Wesley, Bronk, Brian, Creaser, Steffen, Fuller, Nathan, Hubbs, Jed, Pojasek, Kevin, Tate, Barbara

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Organotypic Brain Slice Culture Model of Human Neuroinflammatory Environment Associated with Neurodegeneration von Larson, Kelley C, Tate, Barbara A, Martens, Lauren H

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IP/MS analysis of human CSF Aβ following a single dose of the C-terminal anti-Aβ antibody ponezumab (PF-04360365) to Alzheimer patients von Wood, Kathleen M, McCush, Frederick, Conboy, James J, Durham, Robert, Tate, Barbara, Bednar, Martin M, Landen, Jaren W, Geoghegan, Kieran F, Bales, Kelly R

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