Discovery of a Novel Pyrrole Derivative 1-[5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine Fumarate (TAK-438) as a Potassium-Competitive Acid Blocke... von Arikawa, Yasuyoshi, Nishida, Haruyuki, Kurasawa, Osamu, Hasuoka, Atsushi, Hirase, Keizo, Inatomi, Nobuhiro, Hori, Yasunobu, Matsukawa, Jun, Imanishi, Akio, Kondo, Mitsuyo, Tarui, Naoki, Hamada, Teruki, Takagi, Terufumi, Takeuchi, Toshiyuki, Kajino, Masahiro

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The quick screening of binding compounds and proteins for drug discovery and pharmacological research von Tarui, Naoki

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Structure-based design of a new series of N-(piperidin-3-yl)pyrimidine-5-carboxamides as renin inhibitors von Imaeda, Yasuhiro, Tawada, Michiko, Suzuki, Shinkichi, Tomimoto, Masaki, Kondo, Mitsuyo, Tarui, Naoki, Sanada, Tsukasa, Kanagawa, Ray, Snell, Gyorgy, Behnke, Craig A, Kubo, Keiji, Kuroita, Takanobu

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Discovery, synthesis, and biological evaluation of novel pyrrole derivatives as highly selective potassium-competitive acid blockers von Nishida, Haruyuki, Hasuoka, Atsushi, Arikawa, Yasuyoshi, Kurasawa, Osamu, Hirase, Keizo, Inatomi, Nobuhiro, Hori, Yasunobu, Sato, Fumihiko, Tarui, Naoki, Imanishi, Akio, Kondo, Mitsuyo, Takagi, Terufumi, Kajino, Masahiro

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Molecular Modeling, Design, Synthesis, and Biological Activity of 1H-Pyrrolo[2,3-c]pyridine-7-amine Derivatives as Potassium-Competitive Acid Blockers von Arikawa, Yasuyoshi, Hasuoka, Atsushi, Hirase, Keizo, Inatomi, Nobuhiro, Sato, Fumihiko, Hori, Yasunobu, Takagi, Terufumi, Tarui, Naoki, Kawamoto, Makiko, Kajino, Masahiro

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Generating thermostabilized agonist-bound GPR40/FFAR1 using virus-like particles and a label-free binding assay von Hirozane, Yoshihiko, Motoyaji, Takashi, Maru, Takamitsu, Okada, Kengo, Tarui, Naoki

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Novel approach of fragment-based lead discovery applied to renin inhibitors von Tawada, Michiko, Suzuki, Shinkichi, Imaeda, Yasuhiro, Oki, Hideyuki, Snell, Gyorgy, Behnke, Craig A, Kondo, Mitsuyo, Tarui, Naoki, Tanaka, Toshimasa, Kuroita, Takanobu, Tomimoto, Masaki

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Serum stability of selected decapeptide agonists of KISS1R using pseudopeptides von Asami, Taiji, Nishizawa, Naoki, Ishibashi, Yoshihiro, Nishibori, Kimiko, Nakayama, Masaharu, Horikoshi, Yasuko, Matsumoto, Shin-ichi, Yamaguchi, Masashi, Matsumoto, Hirokazu, Tarui, Naoki, Ohtaki, Tetsuya, Kitada, Chieko

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Synthetic studies of five-membered heteroaromatic derivatives as potassium-competitive acid blockers (P-CABs) von Arikawa, Yasuyoshi, Hasuoka, Atsushi, Nishida, Haruyuki, Hirase, Keizo, Inatomi, Nobuhiro, Takagi, Terufumi, Tarui, Naoki, Kawamoto, Makiko, Imanishi, Akio, Itoh, Fumio, Kajino, Masahiro

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High-Throughput Screening of Potassium-Competitive Acid Blockers von Kondo, Mitsuyo, Kawamoto, Makiko, Hasuoka, Atsushi, Kajino, Masahiro, Inatomi, Nobuhiro, Tarui, Naoki

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A Noncompetitive BACE1 Inhibitor TAK-070 Ameliorates Aβ Pathology and Behavioral Deficits in a Mouse Model of Alzheimer's Disease von Fukumoto, Hiroaki, Takahashi, Hideki, Tarui, Naoki, Matsui, Junji, Tomita, Taisuke, Hirode, Mitsuhiro, Sagayama, Masumi, Maeda, Ryouta, Kawamoto, Makiko, Hirai, Kazuko, Terauchi, Jun, Sakura, Yasufumi, Kakihana, Mitsuru, Kato, Kaneyoshi, Iwatsubo, Takeshi, Miyamoto, Masaomi

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Design, Synthesis, and Biological Evaluation of Novel Investigational Nonapeptide KISS1R Agonists with Testosterone-Suppressive Activity von Asami, Taiji, Nishizawa, Naoki, Matsui, Hisanori, Nishibori, Kimiko, Ishibashi, Yoshihiro, Horikoshi, Yasuko, Nakayama, Masaharu, Matsumoto, Shin-ichi, Tarui, Naoki, Yamaguchi, Masashi, Matsumoto, Hirokazu, Ohtaki, Tetsuya, Kitada, Chieko

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Retraction notice to “3-Benzhydryl-4-piperidones as novel neurokinin-1 receptor antagonists and their efficient synthesis” [Bioorg. Med. Chem. 19 (2011) 5175–5182] von Shirai, Junya, Nakamura, Minoru, Tarui, Naoki, Hashimoto, Tadatoshi, Ikeura, Yoshinori

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Discovery, synthesis, and structure-activity relations of 3,4-dihydro-1H-spiro(naphthalene-2,2′-piperidin)-1-ones as potassium-competitive acid blockers von Imaeda, Toshihiro, Ono, Koji, Nakai, Kazuo, Hori, Yasunobu, Matsukawa, Jun, Takagi, Terufumi, Fujioka, Yasushi, Tarui, Naoki, Kondo, Mitsuyo, Imanishi, Akio, Inatomi, Nobuhiro, Kajino, Masahiro, Itoh, Fumio, Nishida, Haruyuki

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Discovery, synthesis, and structure-activity relations of 3,4-dihydro-1 H -spiro(naphthalene-2,2′-piperidin)-1-ones as potassium-competitive acid blockers von Imaeda, Toshihiro, Ono, Koji, Nakai, Kazuo, Hori, Yasunobu, Matsukawa, Jun, Takagi, Terufumi, Fujioka, Yasushi, Tarui, Naoki, Kondo, Mitsuyo, Imanishi, Akio, Inatomi, Nobuhiro, Kajino, Masahiro, Itoh, Fumio, Nishida, Haruyuki

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Retraction notice to ‘Corrigendum to “3-Benzhydryl-4-piperidones as novel neurokinin-1 receptor antagonists and their efficient synthesis”’ [Bioorg. Med. Chem. 20 (2012) 5668–5668]... von Shirai, Junya, Yamaoka, Masayoshi, Imamiya, Eikoh, Nakamura, Minoru, Tarui, Naoki, Hashimoto, Tadatoshi, Ikeura, Yoshinori

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Physicochemically and Pharmacokinetically Stable Nonapeptide KISS1 Receptor Agonists with Highly Potent Testosterone-Suppressive Activity von Asami, Taiji, Nishizawa, Naoki, Matsui, Hisanori, Takatsu, Yoshihiro, Suzuki, Atsuko, Kiba, Atsushi, Terada, Michiko, Nishibori, Kimiko, Nakayama, Masaharu, Ban, Junko, Matsumoto, Shin-ichi, Tarui, Naoki, Ikeda, Yukihiro, Yamaguchi, Masashi, Kusaka, Masami, Ohtaki, Tetsuya, Kitada, Chieko

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Kinetic resolutions of indan derivatives using bacteria von Tarui, N. (Takeda Chemical Industries Ltd., Osaka (Japan)), Watanabe, H, Fukatsu, K, Ohkawa, S, Nakahama, K

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Novel approach of fragment-based lead discovery applied to renin inhibitors von Tawada, Michiko, Suzuki, Shinkichi, Imaeda, Yasuhiro, Oki, Hideyuki, Snell, Gyorgy, Behnke, Craig A., Kondo, Mitsuyo, Tarui, Naoki, Tanaka, Toshimasa, Kuroita, Takanobu, Tomimoto, Masaki

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Structure-based design of a new series of N -(piperidin-3-yl)pyrimidine-5-carboxamides as renin inhibitors von Imaeda, Yasuhiro, Tawada, Michiko, Suzuki, Shinkichi, Tomimoto, Masaki, Kondo, Mitsuyo, Tarui, Naoki, Sanada, Tsukasa, Kanagawa, Ray, Snell, Gyorgy, Behnke, Craig A., Kubo, Keiji, Kuroita, Takanobu

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