Hepatitis C Virus Core Protein Induces Lipid Droplet Redistribution in a Microtubule- and Dynein-Dependent Manner von Boulant, Steeve, Douglas, Mark W, Moody, Laura, Budkowska, Agata, Targett-Adams, Paul, McLauchlan, John

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Small molecule inhibitors of the hepatitis C virus-encoded NS5A protein von Belda, Oscar, Targett-Adams, Paul

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Visualization of Double-Stranded RNA in Cells Supporting Hepatitis C Virus RNA Replication von Targett-Adams, Paul, Boulant, Steeve, McLauchlan, John

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The Hepatitis C Virus NS4B Protein Can trans-Complement Viral RNA Replication and Modulates Production of Infectious Virus von Jones, Daniel M, Patel, Arvind H, Targett-Adams, Paul, McLauchlan, John

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Maturation of Hepatitis C Virus Core Protein by Signal Peptide Peptidase Is Required for Virus Production von Targett-Adams, Paul, Hope, Graham, Boulant, Steeve, McLauchlan, John

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Structural Determinants That Target the Hepatitis C Virus Core Protein to Lipid Droplets von Boulant, Steeve, Montserret, Roland, Hope, R. Graham, Ratinier, Maxime, Targett-Adams, Paul, Lavergne, Jean-Pierre, Penin, Francois, McLauchlan, John

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Small Molecules Targeting Hepatitis C Virus-Encoded NS5A Cause Subcellular Redistribution of Their Target: Insights into Compound Modes of Action von TARGETT-ADAMS, Paul, GRAHAM, Emily J. S, STAMMEN, Blanda, PRYDE, David, PICKFORD, Chris, WESTBY, Mike, MIDDLETON, Jenny, PALMER, Amy, SHAW, Stephen M, LAVENDER, Helen, BRAIN, Philip, THIEN DUC TRAN, JONES, Lyn H, WAKENHUT, Florian

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Correlation between NS5A Dimerization and Hepatitis C Virus Replication von Lim, Precious J., Chatterji, Udayan, Cordek, Daniel, Sharma, Suresh D., Garcia-Rivera, Jose A., Cameron, Craig E., Lin, Kai, Targett-Adams, Paul, Gallay, Philippe A.

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Site-directed M2 proton channel inhibitors enable synergistic combination therapy for rimantadine-resistant pandemic influenza von Scott, Claire, Kankanala, Jayakanth, Foster, Toshana L, Goldhill, Daniel H, Bao, Peng, Simmons, Katie, Pingen, Marieke, Bentham, Matthew, Atkins, Elizabeth, Loundras, Eleni, Elderfield, Ruth, Claridge, Jolyon K, Thompson, Joseph, Stilwell, Peter R, Tathineni, Ranjitha, McKimmie, Clive S, Targett-Adams, Paul, Schnell, Jason R, Cook, Graham P, Evans, Stephen, Barclay, Wendy S, Foster, Richard, Griffin, Stephen, Lowen, Anice C, Pekosz, Andrew

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The thymidine dideoxynucleoside analog, alovudine, inhibits the mitochondrial DNA polymerase γ, impairs oxidative phosphorylation and promotes monocytic differentiation in acute my... von Yehudai, Dana, Liyanage, Sanduni U, Hurren, Rose, Rizoska, Biljana, Albertella, Mark, Gronda, Marcela, Jeyaraju, Danny V, Wang, Xiaoming, Barghout, Samir H, MacLean, Neil, Siriwardena, Thirushi P, Jitkova, Yulia, Targett-Adams, Paul, Schimmer, Aaron D

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Development and characterization of a transient-replication assay for the genotype 2a hepatitis C virus subgenomic replicon von Targett-Adams, Paul, McLauchlan, John

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Novel L-nucleoside analogue, 5-fluorotroxacitabine, displays potent efficacy against acute myeloid leukemia von Bankar, Aniket, Siriwardena, Thirushi Piyumika, Rizoska, Biljana, Rydergård, Christina, Kylefjord, Helen, Rraklli, Vilma, Eneroth, Anders, Pinho, Pedro, Norin, Stefan, Bylund, Johan, Moses, Sara, Bethell, Richard, Kavanagh, Simon, Maclean, Neil, Gronda, Marcela, Wang, Xiaoming, Hurren, Rose, Minden, Mark D, Targett-Adams, Paul, Schimmer, Aaron D, Albertella, Mark

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3D Spatially Resolved Models of the Intracellular Dynamics of the Hepatitis C Genome Replication Cycle von Knodel, Markus M, Reiter, Sebastian, Targett-Adams, Paul, Grillo, Alfio, Herrmann, Eva, Wittum, Gabriel

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Live Cell Analysis and Targeting of the Lipid Droplet-binding Adipocyte Differentiation-related Protein von Targett-Adams, Paul, Chambers, Doreen, Gledhill, Sarah, Hope, R Graham, Coy, Johannes F, Girod, Andreas, McLauchlan, John

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MAIT cells are activated during human viral infections von van Wilgenburg, Bonnie, Scherwitzl, Iris, Hutchinson, Edward C., Leng, Tianqi, Kurioka, Ayako, Kulicke, Corinna, de Lara, Catherine, Cole, Suzanne, Vasanawathana, Sirijitt, Limpitikul, Wannee, Malasit, Prida, Young, Duncan, Denney, Laura, Moore, Michael D., Fabris, Paolo, Giordani, Maria Teresa, Oo, Ye Htun, Laidlaw, Stephen M., Dustin, Lynn B., Ho, Ling-Pei, Thompson, Fiona M., Ramamurthy, Narayan, Mongkolsapaya, Juthathip, Willberg, Christian B., Screaton, Gavin R., Klenerman, Paul

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The use of AlphaLISA technology to detect interaction between hepatitis C virus-encoded NS5A and cyclophilin A von Waller, Helen, Chatterji, Udayan, Gallay, Philippe, Parkinson, Tanya, Targett-Adams, Paul

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Quantitative Analysis of Hepatitis C NS5A Viral Protein Dynamics on the ER Surface von Knodel, Markus M, Nägel, Arne, Reiter, Sebastian, Vogel, Andreas, Targett-Adams, Paul, McLauchlan, John, Herrmann, Eva, Wittum, Gabriel

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An integrated transcriptomic and meta-analysis of hepatoma cells reveals factors that influence susceptibility to HCV infection von MacPherson, Jamie I, Sidders, Ben, Wieland, Stefan, Zhong, Jin, Targett-Adams, Paul, Lohmann, Volker, Backes, Perdita, Delpuech-Adams, Oona, Chisari, Francis, Lewis, Marilyn, Parkinson, Tanya, Robertson, David L

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Lipid metabolism and HCV infection von Targett-Adams, Paul, Boulant, Steeve, Douglas, Mark W, McLauchlan, John

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Genome-to-genome analysis highlights the effect of the human innate and adaptive immune systems on the hepatitis C virus von Ansari, M Azim, Pedergnana, Vincent, L C Ip, Camilla, Magri, Andrea, Von Delft, Annette, Bonsall, David, Chaturvedi, Nimisha, Bartha, Istvan, Smith, David, Nicholson, George, McVean, Gilean, Trebes, Amy, Piazza, Paolo, Fellay, Jacques, Cooke, Graham, Foster, Graham R, Hudson, Emma, McLauchlan, John, Simmonds, Peter, Bowden, Rory, Klenerman, Paul, Barnes, Eleanor, Spencer, Chris C A

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