Integrated analysis of relapsed B-cell precursor Acute Lymphoblastic Leukemia identifies subtype-specific cytokine and metabolic signatures von Schroeder, Michael P., Bastian, Lorenz, Eckert, Cornelia, Gökbuget, Nicola, James, Alva Rani, Tanchez, Jutta Ortiz, Schlee, Cornelia, Isaakidis, Konstandina, Häupl, Björn, Baum, Katharina, Migueles Lozano, Oscar Arturo, Kouidri, Khouloud, Pan, Kuan-Ting, Urlaub, Henning, Schwartz, Stefan, Burmeister, Thomas, von Stackelberg, Arend, Hoelzer, Dieter, Pfeiffer, Heike, Rieger, Michael A., Göllner, Stefanie, Oellerich, Thomas, Horstman, Martin, Schrappe, Martin, Wolf, Jana, Kirschner-Schwabe, Renate, Brüggemann, Monika, Müller-Tidow, Carsten, Serve, Hubert, Neumann, Martin, Baldus, Claudia D.

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PAX5 biallelic genomic alterations define a novel subgroup of B-cell precursor acute lymphoblastic leukemia von Bastian, Lorenz, Schroeder, Michael P., Eckert, Cornelia, Schlee, Cornelia, Tanchez, Jutta Ortiz, Kämpf, Sebastian, Wagner, Dimitrios L., Schulze, Veronika, Isaakidis, Konstandina, Lázaro-Navarro, Juan, Hänzelmann, Sonja, James, Alva Rani, Ekici, Arif, Burmeister, Thomas, Schwartz, Stefan, Schrappe, Martin, Horstmann, Martin, Vosberg, Sebastian, Krebs, Stefan, Blum, Helmut, Hecht, Jochen, Greif, Philipp A., Rieger, Michael A., Brüggemann, Monika, Gökbuget, Nicola, Neumann, Martin, Baldus, Claudia D.

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FAT1 expression in T-cell acute lymphoblastic leukemia (T-ALL) modulates proliferation and WNT signaling von Liebig, Sven, Neumann, Martin, Silva, Patricia, Ortiz-Tanchez, Jutta, Schulze, Veronika, Isaakidis, Konstandina, Schlee, Cornelia, Schroeder, Michael P., Beder, Thomas, Morris, Luc G. T., Chan, Timothy A., Bastian, Lorenz, Burmeister, Thomas, Schwartz, Stefan, Gökbuget, Nicola, Mochmann, Liliana H., Baldus, Claudia D.

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Long non-coding RNAs defining major subtypes of B cell precursor acute lymphoblastic leukemia von James, Alva Rani, Schroeder, Michael P, Neumann, Martin, Bastian, Lorenz, Eckert, Cornelia, Gökbuget, Nicola, Tanchez, Jutta Ortiz, Schlee, Cornelia, Isaakidis, Konstandina, Schwartz, Stefan, Burmeister, Thomas, von Stackelberg, Arend, Rieger, Michael A, Göllner, Stefanie, Horstman, Martin, Schrappe, Martin, Kirschner-Schwabe, Renate, Brüggemann, Monika, Müller-Tidow, Carsten, Serve, Hubert, Akalin, Altuna, Baldus, Claudia D

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An alternative CYB5A transcript is expressed in aneuploid ALL and enriched in relapse von Bartsch, Lorenz, Schroeder, Michael P, Hänzelmann, Sonja, Bastian, Lorenz, Lázaro-Navarro, Juan, Schlee, Cornelia, Tanchez, Jutta Ortiz, Schulze, Veronika, Isaakidis, Konstandina, Rieger, Michael A, Gökbuget, Nicola, Eckert, Cornelia, Serve, Hubert, Horstmann, Martin, Schrappe, Martin, Brüggemann, Monika, Baldus, Claudia D, Neumann, Martin

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Prognostic implications of mutations and expression of the Wilms tumor 1 (WT1) gene in adult acute T-lymphoblastic leukemia von HEESCH, Sandra, GOEKBUGET, Nicola, HOELZER, Dieter, THIEL, Eckhard, HOFMANN, Wolf-Karsten, BALDUS, Claudia D, STROUX, Andrea, TANCHEZ, Jutta Ortiz, SCHLEE, Cornelia, BURMEISTER, Thomas, SCHWARTZ, Stefan, BLAU, Olga, KEILHOLZ, Ulrich, BUSSE, Antonia

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Molecular subgroups of T-cell acute lymphoblastic leukemia in adults treated according to pediatric-based GMALL protocols von Neumann, Martin, Beder, Thomas, Bastian, Lorenz, Hänzelmann, Sonja, Bultmann, Miriam, Wolgast, Nadine, Hartmann, Alina, Trautmann, Heiko, Ortiz-Tanchez, Jutta, Schlee, Cornelia, Schroeder, Michael, Fransecky, Lars, Vosberg, Sebastian, Fiedler, Walter, Alakel, Nael, Heberling, Lisa, Kondakci, Mustafa, Starck, Michael, Schwartz, Stefan, Raffel, Simon, Müller-Tidow, Carsten, Schneller, Folker, Reichle, Albrecht, Burmeister, Thomas, Greif, Philipp A., Brüggemann, Monika, Gökbuget, Nicola, Baldus, Claudia D.

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Molecular Subgroups of T Cell Acute Lymphoblastic Leukemia in Adults Treated According to GMALL Protocols von Neumann, Martin, Bastian, Lorenz, Hänzelmann, Sonja, Hartmann, Alina, Trautmann, Heiko, Tanchez, Jutta Ortiz, Schlee, Cornelia, Schroeder, Michael P, Fransecky, Lars R., Vosberg, Sebastian, Fiedler, Walter, Alakel, Nael, Kondakci, Mustafa, Starck, Michael, Schwartz, Stefan, Müller-Tidow, Carsten, Schneller, Folker, Reichle, Albert, Burmeister, Thomas, Greif, Philipp A., Brüggemann, Monika, Goekbuget, Nicola, Baldus, Claudia D

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Inhibition of IGF1-R overcomes IGFBP7-induced chemotherapy resistance in T-ALL von Bartram, Isabelle, Erben, Ulrike, Ortiz-Tanchez, Jutta, Blunert, Katja, Schlee, Cornelia, Neumann, Martin, Heesch, Sandra, Baldus, Claudia D

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Multi-Omics of Adult T Cell Acute Lymphoblastic Leukemia von Neumann, Martin, Schroeder, Michael P, Bastian, Lorenz, Tanchez, Jutta Ortiz, Schlee, Cornelia, Isaakidis, Konstandina, James, Alva Rani, Fransecky, Lars R., Vosberg, Sebastian, Krebs, Stefan, Blum, Helmut, Schwartz, Stefan, Burmeister, Thomas, Hoelzer, Dieter, Greif, Philipp A., Brüggemann, Monika, Goekbuget, Nicola, Baldus, Claudia D.

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Homocygous PAX5Sequence Mutations Define a Novel Subtype of B Cell Precursor Acute Lymphoblastic Leukemia von Bastian, Lorenz, Schroeder, Michael P, Eckert, Cornelia, Schlee, Cornelia, Tanchez, Jutta Ortiz, Kämpf, Sebastian, Wagner, Dimitrios L., Schulze, Veronika, Isaakidis, Konstandina, James, Alva Rani, Burmeister, Thomas, Schwartz, Stefan, Vosberg, Sebastian, Krebs, Stefan, Blum, Helmut, Hecht, Jochen, Greif, Philipp A., Rieger, Michael A., Brüggemann, Monika, Goekbuget, Nicola, Müller-Tidow, Carsten, Serve, Hubert, Neumann, Martin, Baldus, Claudia D.

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Molecular Alterations in Refractory Acute Myeloid Leukemia and Persistent Preleukemic Lesions Are Disclosed Using Mesenchymal Stromal Cells As Germline Control von Neumann, Martin, Vosberg, Sebastian, Von Der Heide, Eva Kristin, Schlee, Cornelia, Tanchez, Jutta Ortiz, Isaakidis, Konstandina, Mochmann, Liliana H., Fransecky, Lars R., Graf, Alexander, Krebs, Stefan, Blum, Helmut, Greif, Philipp A., Baldus, Claudia D

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Genomic Profiling Reveals Gain of Mutations in Histone Methylation Regulators in Relapsed Adult B Cell Precursor ALL von Bastian, Lorenz, Neumann, Martin, Gökbuget, Nicola, Schlee, Cornelia, Tanchez, Jutta Ortiz, Vosberg, Sebastian, James, Alva Rani, Schroeder, Michael P, Schwartz, Stefan, Hoelzer, Dieter, Graf, Alexander, Krebs, Stefan, Blum, Helmut, Hecht, Jochen, Brüggemann, Monika, Greif, Philipp A., Baldus, Claudia D.

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Multi-Genomics of Relapsed B-Cell Precursor Acute Lymphoblastic Leukemia Reveals Three Distinct Genetic Clusters Characterized By Different Alterations von Schroeder, Michael P, Neumann, Martin, Eckert, Cornelia, Bastian, Lorenz, James, Alva Rani, Gökbuget, Nicola, Schlee, Cornelia, Ortiz Tanchez, Jutta, Isaakidis, Konstandina, Schwartz, Stefan, Burmeister, Thomas, Hoelzer, Dieter, Pfeiffer, Heike, Rieger, Michael A, Göllner, Stefanie, Oellerich, Thomas, Yepes, Diego, Kirschner-Schwabe, Renate, Brüggemann, Monika, Müller-Tidow, Carsten, Serve, Hubert, Baldus, Claudia D.

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ERG induces a mesenchymal-like state associated with chemoresistance in leukemia cells von Mochmann, Liliana H, Neumann, Martin, von der Heide, Eva K, Nowak, Verena, Kühl, Anja A, Ortiz-Tanchez, Jutta, Bock, Juliane, Hofmann, Wolf K, Baldus, Claudia D

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Molecular Alterations in Bone Marrow Mesenchymal Stroma Cells of AML Patients von von der Heide, Eva, Vosberg, Sebastian, Neumann, Martin, Mochmann, Liliana H., Rani James, Alva, Ortiz Tanchez, Jutta, Schlee, Cornelia, Isaakidis, Konstandina, Luther, Marlene, Graf, Alexander, Krebs, Stefan, Blum, Helmut, Hofmann, Wolf-Karsten, Greif, Philipp A, Baldus, Claudia D

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ERG Overexpression Induces Cell Adhesion Mediated Drug Resistance in Acute Leukemia von Mochmann, Liliana H., Neumann, Martin, Nowak, Verena, Dejewska, Monika, Ortiz-Tanchez, Jutta, Hofmann, Wolf Karsten, Thiel, Eckhard, Baldus, Claudia D

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Antileukemic Activity of the HSP70 Inhibitor Pifithrin-μ von Kaiser, Martin, Kuehnl, Andrea, Ortiz-Tanchez, Jutta, Benlasfer, Ouidad, Schlee, Cornelia, Heesch, Sandra, Thiel, Eckhard, Baldus, Claudia

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Identification of ERG Specific Target Genes by Genome-Wide Screening in T-Lymphoblastic Leukemia von Mochmann, Liliana H, Neumann, Konrad, Bock, Juliane, Tanchez, Jutta Ortiz, Bohne, Arend, Thiel, Eckhard, Hofmann, Wolf K, Baldus, Claudia D

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Wilms Tumor 1 Gene Mutations in Adult Acute T-Lymphoblastic Leukemia von Heesch, Sandra, Goekbuget, Nicola, Tanchez, Jutta Ortiz, Schlee, Cornelia, Schwartz, Stefan, Burmeister, Thomas, Hoelzer, Dieter, Thiel, Eckhard, Hofmann, Wolf K, Baldus, Claudia D

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