Gsk-3-Mediated Proteasomal Degradation of ATF4 Is a Proapoptotic Mechanism in Mouse Pancreatic β-Cells von Nagao, Yuko, Amo-Shiinoki, Kikuko, Nakabayashi, Hiroko, Hatanaka, Masayuki, Kondo, Manabu, Matsunaga, Kimie, Emoto, Masahiro, Okuya, Shigeru, Tanizawa, Yukio, Tanabe, Katsuya

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Wolfram syndrome in the Japanese population; molecular analysis of WFS1 gene and characterization of clinical features von Matsunaga, Kimie, Tanabe, Katsuya, Inoue, Hiroshi, Okuya, Shigeru, Ohta, Yasuharu, Akiyama, Masaru, Taguchi, Akihiko, Kora, Yukari, Okayama, Naoko, Yamada, Yuichiro, Wada, Yasuhiko, Amemiya, Shin, Sugihara, Shigetaka, Nakao, Yuzo, Oka, Yoshitomo, Tanizawa, Yukio

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Deficiency of WFS1 leads to the impairment of AVP secretion under dehydration in male mice von Kurimoto, Junki, Takagi, Hiroshi, Miyata, Takashi, Hodai, Yuichi, Kawaguchi, Yohei, Hagiwara, Daisuke, Suga, Hidetaka, Kobayashi, Tomoko, Sugiyama, Mariko, Onoue, Takeshi, Ito, Yoshihiro, Iwama, Shintaro, Banno, Ryoichi, Tanabe, Katsuya, Tanizawa, Yukio, Arima, Hiroshi

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Inhibition of Foxo1 Protects Pancreatic Islet β-Cells Against Fatty Acid and Endoplasmic Reticulum Stress–Induced Apoptosis von Martinez, Sara C, Tanabe, Katsuya, Cras-Méneur, Corentin, Abumrad, Nada A, Bernal-Mizrachi, Ernesto, Permutt, M Alan

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Selective proteasome degradation of C‐terminally‐truncated human WFS1 in pancreatic beta cells von Tokuma, Hiraku, Sakano, Daisuke, Tanabe, Katsuya, Tanizawa, Yukio, Shiraki, Nobuaki, Kume, Shoen

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Islet cell dedifferentiation is a pathologic mechanism of long-standing progression of type 2 diabetes von Amo-Shiinoki, Kikuko, Tanabe, Katsuya, Hoshii, Yoshinobu, Matsui, Hiroto, Harano, Risa, Fukuda, Tatsuya, Takeuchi, Takato, Bouchi, Ryotaro, Takagi, Tokiyo, Hatanaka, Masayuki, Takeda, Komei, Okuya, Shigeru, Nishimura, Wataru, Kudo, Atsushi, Tanaka, Shinji, Tanabe, Minoru, Akashi, Takumi, Yamada, Tetsuya, Ogawa, Yoshihiro, Ikeda, Eiji, Nagano, Hiroaki, Tanizawa, Yukio

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A case of multiple glucagonomas with no clinical manifestations of excess glucagon despite hyperglucagonemia von Amano, Shogo, Suenaga, Shigeyuki, Hamamoto, Kaori, Yada, Shoko, Tsuyama, Takanori, Shinoda, Shuhei, Tanaka, Yuya, Takemoto, Yoshihiro, Harada, Eijiro, Tanabe, Katsuya, Asahara, Shunichiro, Hoshii, Kazunobu, Takami, Taro

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Interorgan Crosstalk Contributing to β-Cell Dysfunction von Tanizawa, Yukio, Hatanaka, Masayuki, Amo-Shiinoki, Kikuko, Tanabe, Katsuya

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Metformin: Pharmacological Action and Nutritional Metabolism von Tanabe, Katsuya

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Hachimijiogan, a traditional herbal medicine, modulates adipose cell function and ameliorates diet-induced obesity and insulin resistance in mice von Kagawa, Syota, Tanabe, Katsuya, Hiromura, Makoto, Ogawa, Kakuyou, Koga, Takayuki, Maeda, Takahiro, Amo-Shiinoki, Kikuko, Ochi, Hiroyuki, Ichiki, Yui, Fukuyama, Shogo, Suzuki, Saori, Suizu, Natsuki, Ohmine, Takaaki, Hamachi, Sakurako, Tsuneki, Hiroshi, Okuya, Shigeru, Sasaoka, Toshiyasu, Tanizawa, Yukio, Nagashima, Fumihiro

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A patient with sudden hearing loss induced by propylthiouracil von Tanabe, Katsuya, Nishimura, Shogo, Sugahara, Kazuma, Yamashita, Hiroshi, Tanizawa, Yukio

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Glucose and fatty acids synergize to promote B-cell apoptosis through activation of glycogen synthase kinase 3β independent of JNK activation von Tanabe, Katsuya, Liu, Yang, Hasan, Syed D, Martinez, Sara C, Cras-Méneur, Corentin, Welling, Cris M, Bernal-Mizrachi, Ernesto, Tanizawa, Yukio, Rhodes, Christopher J, Zmuda, Erik, Hai, Tsonwin, Abumrad, Nada A, Permutt, M Alan

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Comprehensive overview of disease models for Wolfram syndrome: toward effective treatments von Morikawa, Shuntaro, Tanabe, Katsuya, Kaneko, Naoya, Hishimura, Nozomi, Nakamura, Akie

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Differences in the Contribution of HLA-DR and -DQ Haplotypes to Susceptibility to Adult- and Childhood-Onset Type 1 Diabetes in Japanese Patients von MURAO, Satoshi, MAKINO, Hideichi, KONDO, Shiori, TANAKA, Kiyonobu, TARUMI, Yoshinao, SETO, Isamu, KATO, Kenichi, OHNO, Keizo, KUSUNOKI, Yukiko, EBISUI, Osamu, TAKADA, Yasuharu, TANABE, Katsuya, KAINO, Yukikazu, TAKEMOTO, Koji, ONUMA, Hiroshi, NISHIMIYA, Tatsuya, OSAWA, Haruhiko, KONOUE, Etsushi, OHASHI, Jun, KIDA, Kaichi, FUJII, Yasuhisa, SHIMIZU, Ikki, KAWASAKI, Eiji, FUJIYAMA, Masao

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Activation of GLP-1 receptor signalling alleviates cellular stresses and improves beta cell function in a mouse model of Wolfram syndrome von Kondo, Manabu, Tanabe, Katsuya, Amo-Shiinoki, Kikuko, Hatanaka, Masayuki, Morii, Tsukasa, Takahashi, Harumi, Seino, Susumu, Yamada, Yuichiro, Tanizawa, Yukio

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323-LB: Activation of the GLP-1 Receptor Signaling Prevents Beta-Cell Dedifferentiation in a Mouse Model of Wolfram Syndrome through Modulating TXNIP Expression von TANABE, KATSUYA, AMO-SHIINOKI, KIKUKO, HATANAKA, MASAYUKI, TANIZAWA, YUKIO

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Troglitazone Treatment Increases Plasma Vascular Endothelial Growth Factor in Diabetic Patients and Its mRNA in 3T3-L1 Adipocytes von EMOTO, Masahiro, ANNO, Takatoshi, SATO, Yutaka, TANABE, Katsuya, OKUYA, Shigeru, TANIZAWA, Yukio, MATSUTANI, Akira, OKA, Yoshitomo

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Metabolic Insufficiency Caused By Cellular Stresses Is Implicated in Beta-Cell Dedifferentiation in the Mouse Model of Wolfram Syndrome von AMO-SHIINOKI, KIKUKO, TANABE, KATSUYA, HATANAKA, MASAYUKI, TANIZAWA, YUKIO

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Importance of Intestinal Environment and Cellular Plasticity of Islets in the Development of Postpancreatectomy Diabetes von Fukuda, Tatsuya, Bouchi, Ryotaro, Takeuchi, Takato, Amo-Shiinoki, Kikuko, Kudo, Atsushi, Tanaka, Shinji, Tanabe, Minoru, Akashi, Takumi, Hirayama, Kazuhiro, Odamaki, Toshitaka, Igarashi, Miki, Kimura, Ikuo, Tanabe, Katsuya, Tanizawa, Yukio, Yamada, Tetsuya, Ogawa, Yoshihiro

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2037-P: Islet ß-Cell Dedifferentiation Is Involved in Progression of Type 2 Diabetes von AMO-SHIINOKI, KIKUKO, TANABE, KATSUYA, BOUCHI, RYOTARO, NISHIMURA, WATARU, OGAWA, YOSHIHIRO, TANIZAWA, YUKIO

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