[28] Use and specificity of staurosporine, UCN-O1, and calphostin C as protein kinase inhibitors von Tamaoki, Tatsuya

Volltext

Calphostin C (UCN-1028C), a novel microbial compound, is a highly potent and specific inhibitor of protein kinase C von Kobayashi, Eiji, Nakano, Hirofumi, Morimoto, Makoto, Tamaoki, Tatsuya

Volltext

Antitumor activity of 2-chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl) adenine, a novel deoxyadenosine analog, against human colon tumor xenografts by oral administration von TAKAHASHI, T, KANAZAWA, J, AKINAGA, S, TAMAOKI, T, OKABE, M

Volltext

UCS15A, a non-kinase inhibitor of Src signal transduction von SHARMA, Sreenath V, ONEYAMA, Chitose, YAMASHITA, Yoshinori, NAKANO, Hirofumi, SUGAWARA, Katsura, HAMADA, Masako, KOSAKA, Nobuo, TAMAOKI, Tatsuya

Volltext

Inhibition of lymphocyte kinase Lck and phosphatidylinositol 3-kinase by a novel immunosuppressant, lymphostin von Nagata, H. (Kyowa Hakko Kogyo Co. Ltd., Machida, Tokyo (Japan). Tokyo Research Lab.), Yano, H, Sasaki, K, Sato, S, Nakanishi, S, Takahashi, I, Tamaoki, T

Volltext

STAUROSPORINE INHIBITS TYROSINE-SPECIFIC PROTEIN KINASE ACTIVITY OF ROUS SARCOMA VIRUS TRANSFORMING PROTEIN p60 von NAKANO, HIROFUMI, KOBAYASHI, EIJI, TAKAHASHI, ISAMI, TAMAOKI, TATSUYA, KUZUU, YASUKO, IBA, HIDEO

Volltext

Lymphostin (LK6-A), a novel immunosuppressant from Streptomyces sp. KY11783 : Taxonomy of the producing organism, fermentation, isolation and biological activities von NAGATA, H, OCHIAI, K, AOTANI, Y, ANDO, K, YOSHIDA, M, TAKAHASHI, I, TAMAOKI, T

Volltext

UCN-01 AND UCN-02, NEW SELECTIVE INHIBITORS OF PROTEIN KINASE C: II. PURIFICATION, PHYSICO-CHEMICAL PROPERTIES STRUCTURAL DETERMINATION AND BIOLOGICAL ACTIVITIES von TAKAHASHI, ISAMI, SAITOH, YUTAKA, YOSHIDA, MAYUMI, SANO, HIROSHI, NAKANO, HIROFUMI, MORIMOTO, MAKOTO, TAMAOKI, TATSUYA

Volltext

CALPHOSTINS (UCN-1028), NOVEL AND SPECIFIC INHIBITORS OF PROTEIN KINASE C: I. FERMENTATION, ISOLATION, PHYSICO-CHEMICAL PROPERTIES AND BIOLOGICAL ACTIVITIES von KOBAYASHI, EIJI, ANDO, KATSUHIKO, NAKANO, HIROFUMI, IIDA, TAKAO, OHNO, HIROE, MORIMOTO, MAKOTO, TAMAOKI, TATSUYA

Volltext

KF25706, a novel oxime derivative of radicicol, exhibits in vivo antitumor activity via selective depletion of Hsp90 binding signaling molecules von SOGA, S, NECKERS, L. M, AKINAGA, S, SCHULTE, T. W, SHIOTSU, Y, AKASAKA, K, NARUMI, H, AGATSUMA, T, IKUINA, Y, MURAKATA, C, TAMAOKI, T

Volltext

UCN‐01 selectively enhances mitomycin C cytotoxicity in p53 defective cells which is mediated through S and/or G2 checkpoint abrogation von Sugiyama, Kazuyo, Shimizu, Makiko, Akiyama, Tadakazu, Tamaoki, Tatsuya, Yamaguchi, Ken, Takahashi, Rei, Eastman, Alan, Akinaga, Shiro

Volltext

Lymphostin (LK6-A), a Novel Immunosuppressant from Streptomyces sp. KYI 1783: Taxonomy of the Producing Organism, Fermentation, Isolation and Biological Activities von NAGATA, HIROYUKI, OCHIAI, KEIKO, AOTANI, YUMIKO, ANDO, KATSUHIKO, YOSHIDA, MAYUMI, TAKAHASHI, ISAMI, TAMAOKI, TATSUYA

Volltext

UCN-01 AND UCN-02, NEW SELECTIVE INHIBITORS OF PROTEIN KINASE C: I. SCREENING, PRODUCING ORGANISM AND FERMENTATION von TAKAHASHI, ISAMI, ASANO, Kozo, KAWAMOTO, ISAO, TAMAOKI, TATSUYA, NAKANO, HIROFUMI

Volltext

Synthesis and antitumor activity of novel C-8 ester derivatives of leinamycin von Kanda, Yutaka, Ashizawa, Tadashi, Kawashima, Kenji, Ikeda, Shun-ichi, Tamaoki, Tatsuya

Volltext

Stereospecific antitumor activity of radicicol oxime derivatives von SOGA, Shiro, SHARMA, Sreenath V, SCHULTE, Theodor W, NECKERS, Leonard M, AKINAGA, Shiro, SHIOTSU, Yukimasa, SHIMIZU, Makiko, TAHARA, Harunobu, YAMAGUCHI, Kazuo, IKUINA, Yoji, MURAKATA, Chikara, TAMAOKI, Tatsuya, KUREBAYASHI, Junichi

Volltext

Constituents of a fern, Davallia mariesii MOORE. V: Isolation and structures of davallin, a new tetrameric proanthocyanidin, and two new phenolic glycosides von CHENG-BIN CUI, TEZUKA, Y, YAMASHITA, H, KIKUCHI, T, NAKANO, H, TAMAOKI, T, JONG-HEE PARK

Volltext

Decrease in susceptibility toward induction of apoptosis and alteration in G1 checkpoint function as determinants of resistance of human lung cancer cells against the antisignaling... von SUGIYAMA, K, AKIYAMA, T, SHIMIZU, M, TAMAOKI, T, COURAGE, C, GESCHER, A, AKINAGA, S

Volltext

Hypericin and pseudohypericin specifically inhibit protein kinase C: Possible relation to their antiretroviral activity von Takahashi, Isami, Nakanishi, Satoshi, Kobayashi, Eiji, Nakano, Hirofumi, Suzuki, Kohichi, Tamaoki, Tatsuya

Volltext

UCA1064-B, a new antitumor antibiotic isolated from Wallemia sebi: production, isolation and structural determination von Takahashi, I, Maruta, R, Ando, K, Yoshida, M, Iwasaki, T, Kanazawa, J, Okabe, M, Tamaoki, T

Volltext

TETROCARCINS, NOVEL ANTITUMOR ANTIBIOTICS: I. PRODUCING ORGANISM, FERMENTATION AND ANTIMICROBIAL ACTIVITY von TOMITA, FUSAO, TAMAOKI, TATSUYA

Volltext