Deletion of the MAD2L1 spindle assembly checkpoint gene is tolerated in mouse models of acute T-cell lymphoma and hepatocellular carcinoma von Foijer, Floris, Albacker, Lee A, Bakker, Bjorn, Spierings, Diana C, Yue, Ying, Xie, Stephanie Z, Davis, Stephanie, Lutum-Jehle, Annegret, Takemoto, Darin, Hare, Brian, Furey, Brinley, Bronson, Roderick T, Lansdorp, Peter M, Bradley, Allan, Sorger, Peter K

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Hepatitis C Virus Variants with Decreased Sensitivity to Direct-Acting Antivirals (DAAs) Were Rarely Observed in DAA-Naive Patients prior to Treatment von Bartels, Doug J, Sullivan, James C, Zhang, Eileen Z, Tigges, Ann M, Dorrian, Jennifer L, De Meyer, Sandra, Takemoto, Darin, Dondero, Elizabeth, Kwong, Ann D, Picchio, Gaston, Kieffer, Tara L

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Potentiation of tumor responses to DNA damaging therapy by the selective ATR inhibitor VX-970 von Hall, Amy B, Newsome, Dave, Wang, Yuxin, Boucher, Diane M, Eustace, Brenda, Gu, Yong, Hare, Brian, Johnson, Mac A, Milton, Sean, Murphy, Cheryl E, Takemoto, Darin, Tolman, Crystal, Wood, Mark, Charlton, Peter, Charrier, Jean-Damien, Furey, Brinley, Golec, Julian, Reaper, Philip M, Pollard, John R

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A Surface Plasmon Resonance Assay for the Binding of Influenza Virus Hemagglutinin to Its Sialic Acid Receptor von TAKEMOTO, DARIN K., SKEHEL, JOHN J., WILEY, DON C.

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Abstract PR02: Aneuploidy as a driver of liver cancer von Albacker, Lee A., Foijer, Floris, Yue, Ying, Takemoto, Darin, Davis, Stehpanie, Bronson, Rodney T., Sorger, Peter K.

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Abstract 3711: Pre-clinical combinations of ATR and PARP inhibitors: Defining target patient populations and dose schedule von Pollard, John, Reaper, Phil, Peek, Adele, Hughes, Stuart, Djeha, Hakim, Cummings, Steven, Larbi, Karen, Penney, Marina, Sullivan, Jim, Takemoto, Darin, DeFranco, Chris

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Abstract 1644: VX-970, the first-in-class inhibitor of the DNA damage repair enzyme ATR von Pollard, John, Reaper, Philip, Jones, Julie, Barnes, Christopher, Gladwell, Scott, Hughes, Stuart, Peak, Adele, Djeha, Hakim, Hall, Amy, Newsome, David, Wang, Yuxin, Boucher, Diane, Eustace, Brenda, Gu, Yong, Hare, Brian, Johnson, Mac, Milton, Sean, Murphy, Cheryl, Takemoto, Darin, Tolman, Crystal, Wood, Mark, Furey, Brinley, Penney, Marina, Li, Howard, Defranco, Christopher, Asmal, Mohammed, Fields, Scott

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Abstract LB-299: Comprehensive preclinical evaluation of VE-822, the first ATR-targeted drug candidate: a novel approach to transforming the efficacy of DNA damaging agents von Boucher, Diane, Charlton, Peter, Charrier, Jean-Damien, Furey, Brinley, Gu, Yong, Hall, Amy, Hare, Brian, Li, Howard, Milton, Sean, Murphy, Cheryl, Reaper, Philip, Takemoto, Darin, Udagawa, Taturo, Wang, Yuxin, Wood, Mark, Pollard, John

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Abstract 5491: Evaluation of the first potent and highly selective inhibitor of ATR kinase: An approach to selectively sensitize cancer cells to genotoxic drugs von Pollard, John R., Caron, Paul, Charlton, Peter, Charrier, Jean-Damien, Golec, Julian, Griffiths, Matthew, Hall, Amy, Hare, Brian, Long, Joanna, MacCormick, Somhairle, Milton, Sean, Murcko, Mark, Murphy, Cheryl, Peek, Adele, Reaper, Philip, Takemoto, Darin

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COMPACT PROTEINS von DOKSHIN, Gregoriy A, SAHA, Jishnu, NELSON, D'anna M, GOOD, Michelle, TAKEMOTO, Darin Katsumi, SWIFT, Sara Elizabeth, MCGAUGHEY NICHOLLS, Georgia

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Studies of the Binding Properties of Influenza Hemagglutinin Receptor-Site Mutants von Martín, Javier, Wharton, Stephen A., Lin, Yi Pu, Takemoto, Darin K., Skehel, John J., Wiley, Don C., Steinhauer, David A.

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METHODS OF CANCER TREATMENT USING AN ATR INHIBITOR von PENNEY, Marina, SULLIVAN, James, REAPER, Philip Michael, GEHO, David, TAKEMOTO, Darin, POLLARD, John Robert

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METHODS OF CANCER TREATMENT USING AN ATR INHIBITOR von SULLIVAN, James, REAPER, Philip Michael, GEHO, David, PENNEY, Marina S, TAKEMOTO, Darin, POLLARD, John Robert

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ANTIPROLIFERATION COMPOUNDS AND USES THEREOF von WANG, Tiansheng, LAUFFER, David J, YU, Henry, KULKARNI, Shashank, COLLIER, Philip, BEMIS, Guy, WAAL, Nathan, TAKEMOTO, Darin, DONG, Huijun, CHANDUPATLA, Kishan, CLARK, Michael, HOOVER, Russell, PENNEY, Marina, LI, Pan, DENG, Hongbo, RONKIN, Steven, DORSCH, Warren, BOYD, Michael, TANG, Qing, JOHNSON, Mac

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ANTIPROLIFERATION COMPOUNDS AND USES THEREOF von Takemoto, Darin, Li, Pan, Bemis, Guy, Dorsch, Warren, Johnson, Mac Arthur Jr, Boyd, Michael, Deng, Hongbo, Wang, Tiansheng, Penney, Marina, Ronkin, Steven, Yu, Henry, Clark, Michael, Chandupatla, Kishan, Tang, Qing, Kulkarni, Shashank, Collier, Philip, Lauffer, David J, Waal, Nathan D, Dong, Huijun, Hoover, Russell R

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ANTIPROLIFERATION COMPOUNDS AND USES THEREOF von LI, PAN, CHANDUPATLA, KISHAN, HOOVER, RUSSELL R, JOHNSON, MAC ARTHUR JR, LAUFFER, DAVID J, COLLIER, PHILIP, TANG, QING, DORSCH, WARREN, KULKARNI, SHASHANK, YU, HENRY, WANG, TIANSHENG, BOYD, MICHAEL, DONG, HUIJUN, WAAL, NATHAN D, CLARK, MICHAEL, RONKIN, STEVEN, BEMIS, GUY, PENNEY, MARINA, DENG, HONGBO, TAKEMOTO, DARIN

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PTERIDINONE COMPOUNDS AND USES THEREOF von Takemoto, Darin, Li, Pan, Gu, Wenxin, Bemis, Guy, Dorsch, Warren, Boyd, Michael, Deng, Hongbo, Wang, Tiansheng, Ledeboer, Mark Willem, Penney, Marina, Ledford, Brian, LAUFFER, David, Maltais, Francois, Deininger, David, Waal, Nathan D, Hoover, Russell R, Johnson, JR., Mac Arthur

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METHODS OF CANCER TREATMENT USING AN ATR INHIBITOR von PENNEY, Marina, SULLIVAN, James, REAPER, Philip Michael, GEHO, David, TAKEMOTO, Darin, POLLARD, John Robert

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ANTIPROLIFERATION COMPOUNDS AND USES THEREOF von WANG, Tiansheng, LAUFFER, David J, JOHNSON, Mac, Arthur, JR, WAAL, Nathan, D, YU, Henry, HOOVER, Russell, R, KULKARNI, Shashank, COLLIER, Philip, BEMIS, Guy, TAKEMOTO, Darin, DONG, Huijun, CHANDUPATLA, Kishan, CLARK, Michael, PENNEY, Marina, LI, Pan, DENG, Hongbo, RONKIN, Steven, DORSCH, Warren, BOYD, Michael, TANG, Qing

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METHODS OF CANCER TREATMENT USING AN ATR INHIBITOR von PENNEY, Marina, SULLIVAN, James, REAPER, Philip Michael, GEHO, David, TAKEMOTO, Darin, POLLARD, John Robert

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