Modified forelimb grip strength test detects aging-associated physiological decline in skeletal muscle function in male mice von Takeshita, Hikari, Yamamoto, Koichi, Nozato, Satoko, Inagaki, Tadakatsu, Tsuchimochi, Hirotsugu, Shirai, Mikiyasu, Yamamoto, Ryohei, Imaizumi, Yuki, Hongyo, Kazuhiro, Yokoyama, Serina, Takeda, Masao, Oguro, Ryosuke, Takami, Yoichi, Itoh, Norihisa, Takeya, Yasushi, Sugimoto, Ken, Fukada, So-ichiro, Rakugi, Hiromi

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Clinical Characteristics and Postoperative Outcomes of Primary Aldosteronism in the Elderly von Takeda, Masao, Yamamoto, Koichi, Akasaka, Hiroshi, Rakugi, Hiromi, Naruse, Mitsuhide, Takeda, Yoshiyu, Kurihara, Isao, Itoh, Hiroshi, Umakoshi, Hironobu, Tsuiki, Mika, Ichijo, Takamasa, Katabami, Takuyuki, Wada, Norio, Shibayama, Yui, Yoshimoto, Takanobu, Ogawa, Yoshihiro, Kawashima, Junji, Sone, Masakatsu, Inagaki, Nobuya, Takahashi, Katsutoshi, Fujita, Megumi, Watanabe, Minemori, Matsuda, Yuichi, Kobayashi, Hiroki, Shibata, Hirotaka, Kamemura, Kohei, Otsuki, Michio, Fujii, Yuichi, Ogo, Atsushi, Okamura, Shintaro, Miyauchi, Shozo, Yanase, Toshihiko, Suzuki, Tomoko, Kawamura, Takashi

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Loss of ACE2 Exaggerates High-Calorie Diet―Induced Insulin Resistance by Reduction of GLUT4 in Mice von TAKEDA, Masao, YAMAMOTO, Koichi, TAKEYA, Yasushi, SUGIMOTO, Ken, KAMIDE, Kei, OHISHI, Mitsuru, RAKUGI, Hiromi, TAKEMURA, Yukihiro, TAKESHITA, Hikari, HONGYO, Kazuhiro, KAWAI, Tatsuo, HANASAKI-YAMAMOTO, Hiroko, OGURO, Ryosuke, TAKAMI, Yoichi, TATARA, Yuji

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The counterregulating role of ACE2 and ACE2-mediated angiotensin 1-7 signaling against angiotensin II stimulation in vascular cells von Hayashi, Norihiro, Yamamoto, Koichi, Ohishi, Mitsuru, Tatara, Yuji, Takeya, Yasushi, Shiota, Atsushi, Oguro, Ryosuke, Iwamoto, Yoshihiro, Takeda, Masao, Rakugi, Hiromi

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Longitudinal association of hypertension and diabetes mellitus with cognitive functioning in a general 70-year-old population: the SONIC study von Ryuno, Hirochika, Kamide, Kei, Gondo, Yasuyuki, Kabayama, Mai, Oguro, Ryosuke, Nakama, Chikako, Yokoyama, Serina, Nagasawa, Motonori, Maeda-Hirao, Satomi, Imaizumi, Yuki, Takeya, Miyuki, Yamamoto, Hiroko, Takeda, Masao, Takami, Yoichi, Itoh, Norihisa, Takeya, Yasushi, Yamamoto, Koichi, Sugimoto, Ken, Nakagawa, Takeshi, Yasumoto, Saori, Ikebe, Kazunori, Inagaki, Hiroki, Masui, Yukie, Takayama, Michiyo, Arai, Yasumichi, Ishizaki, Tatsuro, Takahashi, Ryutaro, Rakugi, Hiromi

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Angiotensin‐converting enzyme 2 deficiency accelerates and angiotensin 1‐7 restores age‐related muscle weakness in mice von Takeshita, Hikari, Yamamoto, Koichi, Nozato, Satoko, Takeda, Masao, Fukada, So‐ichiro, Inagaki, Tadakatsu, Tsuchimochi, Hirotsugu, Shirai, Mikiyasu, Nozato, Yoichi, Fujimoto, Taku, Imaizumi, Yuki, Yokoyama, Serina, Nagasawa, Motonori, Hamano, Go, Hongyo, Kazuhiro, Kawai, Tatsuo, Hanasaki‐Yamamoto, Hiroko, Takeda, Shuko, Takahashi, Toshimasa, Akasaka, Hiroshi, Itoh, Norihisa, Takami, Yoichi, Takeya, Yasushi, Sugimoto, Ken, Nakagami, Hironori, Rakugi, Hiromi

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Oxidized LDL (oxLDL) activates the angiotensin II type 1 receptor by binding to the lectin‐like oxLDL receptor von Yamamoto, Koichi, Kakino, Akemi, Takeshita, Hikari, Hayashi, Norihiro, Li, Lei, Nakano, Atsushi, Hanasaki‐Yamamoto, Hiroko, Fujita, Yoshiko, Imaizumi, Yuki, Toyama‐Yokoyama, Serina, Nakama, Chikako, Kawai, Tatsuo, Takeda, Masao, Hongyo, Kazuhiro, Oguro, Ryosuke, Maekawa, Yoshihiro, Itoh, Norihisa, Takami, Yoichi, Onishi, Miyuki, Takeya, Yasushi, Sugimoto, Ken, Kamide, Kei, Nakagami, Hironori, Ohishi, Mitsuru, Kurtz, Theodore W., Sawamura, Tatsuya, Rakugi, Hiromi

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Serum albumin/globulin ratio is associated with cognitive function in community‐dwelling older people: The Septuagenarians, Octogenarians, Nonagenarians Investigation with Centenar... von Maeda, Satomi, Takeya, Yasushi, Oguro, Ryosuke, Akasaka, Hiroshi, Ryuno, Hirochika, Kabayama, Mai, Yokoyama, Serina, Nagasawa, Motonori, Fujimoto, Taku, Takeda, Masao, Onishi‐Takeya, Miyuki, Itoh, Norihisa, Takami, Yoichi, Yamamoto, Koichi, Sugimoto, Ken, Inagaki, Hiroki, Ogawa, Madoka, Nakagawa, Takeshi, Yasumoto, Saori, Masui, Yukie, Arai, Yasumichi, Ishizaki, Tatsuro, Ikebe, Kazunori, Gondo, Yasuyuki, Kamide, Kei, Rakugi, Hiromi

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Factors associated with the severity of obstructive sleep apnea in older adults von Hongyo, Kazuhiro, Ito, Norihisa, Yamamoto, Koichi, Yasunobe, Yukiko, Takeda, Masao, Oguro, Ryosuke, Takami, Yoichi, Takeya, Yasushi, Sugimoto, Ken, Rakugi, Hiromi

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Comparison between L-type and N/L-type calcium channel blockers in the regulation of home blood-pressure variability in elderly hypertensive patients von Nozato, Satoko, Yamamoto, Koichi, Nozato, Yoichi, Takeda, Masao, Hongyo, Kazuhiro, Takeya, Miyuki, Akasaka, Hiroshi, Takami, Yoichi, Takeya, Yasushi, Sugimoto, Ken, Ito, Norihisa, Rakugi, Hiromi

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High plasma adiponectin levels are associated with frailty in a general old‐old population: The Septuagenarians, Octogenarians, Nonagenarians Investigation with Centenarians study... von Nagasawa, Motonori, Takami, Yoichi, Akasaka, Hiroshi, Kabayama, Mai, Maeda, Satomi, Yokoyama, Serina, Fujimoto, Taku, Nozato, Yoichi, Imaizumi, Yuki, Takeda, Masao, Itoh, Norihisa, Takeya, Yasushi, Yamamoto, Koichi, Sugimoto, Ken, Nakagawa, Takeshi, Masui, Yukie, Arai, Yasumichi, Ishizaki, Tatsuro, Ikebe, Kazunori, Gondo, Yasuyuki, Kamide, Kei, Rakugi, Hiromi

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Loss of ACE2 accelerates time-dependent glomerular and tubulointerstitial damage in streptozotocin-induced diabetic mice von Shiota, Atsushi, Yamamoto, Koichi, Ohishi, Mitsuru, Tatara, Yuji, Ohnishi, Miyuki, Maekawa, Yoshihiro, Iwamoto, Yoshihiro, Takeda, Masao, Rakugi, Hiromi

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Differences in the association between high blood pressure and cognitive functioning among the general Japanese population aged 70 and 80 years: The SONIC study von Ryuno, Hirochika, Kamide, Kei, Gondo, Yasuyuki, Nakama, Chikako, Oguro, Ryosuke, Kabayama, Mai, Kawai, Tatsuo, Kusunoki, Hiroshi, Yokoyama, Serina, Imaizumi, Yuki, Takeya, Miyuki, Yamamoto, Hiroko, Takeda, Masao, Takami, Yoichi, Itoh, Norihisa, Yamamoto, Koichi, Takeya, Yasushi, Sugimoto, Ken, Nakagawa, Takeshi, Ikebe, Kazunori, Inagaki, Hiroki, Masui, Yukie, Ishizaki, Tatsuro, Takayama, Michiyo, Arai, Yasumichi, Takahashi, Ryutaro, Rakugi, Hiromi

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The endocytosis of oxidized LDL via the activation of the angiotensin II type 1 receptor von Takahashi, Toshimasa, Huang, Yibin, Yamamoto, Koichi, Hamano, Go, Kakino, Akemi, Kang, Fei, Imaizumi, Yuki, Takeshita, Hikari, Nozato, Yoichi, Nozato, Satoko, Yokoyama, Serina, Nagasawa, Motonori, Kawai, Tatsuo, Takeda, Masao, Fujimoto, Taku, Hongyo, Kazuhiro, Nakagami, Futoshi, Akasaka, Hiroshi, Takami, Yoichi, Takeya, Yasushi, Sugimoto, Ken, Gaisano, Herbert Y., Sawamura, Tatsuya, Rakugi, Hiromi

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Severity of obstructive sleep apnea is associated with the nocturnal fluctuation of pulse rate, but not with that of blood pressure, in older hypertensive patients receiving calciu... von Nozato, Satoko, Yamamoto, Koichi, Nozato, Yoichi, Akasaka, Hiroshi, Hongyo, Kazuhiro, Takeda, Masao, Takami, Yoichi, Takeya, Yasushi, Sugimoto, Ken, Ito, Norihisa, Rakugi, Hiromi

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Association between long-term care and chronic and lifestyle-related disease modified by social profiles in community-dwelling people aged 80 and 90; SONIC study von Kiyoshige, Eri, Kabayama, Mai, Gondo, Yasuyuki, Masui, Yukie, Ryuno, Hirochika, Sawayama, Yasuka, Inoue, Takako, Akagi, Yuya, Sekiguchi, Toshiaki, Tanaka, Kentaro, Nakagawa, Takeshi, Yasumoto, Saori, Ogawa, Madoka, Inagaki, Hiroki, Oguro, Ryousuke, Sugimoto, Ken, Akasaka, Hiroshi, Yamamoto, Koichi, Takeya, Yasushi, Takami, Yoichi, Itoh, Norihisa, Takeda, Masao, Nagasawa, Motonori, Yokoyama, Serina, Maeda, Satomi, Ikebe, Kazunori, Arai, Yasumichi, Ishizaki, Tatsuro, Rakugi, Hiromi, Kamide, Kei

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Telmisartan modulates mitochondrial function in vascular smooth muscle cells von Takeuchi, Kiyo, Yamamoto, Koichi, Ohishi, Mitsuru, Takeshita, Hikari, Hongyo, Kazuhiro, Kawai, Tatsuo, Takeda, Masao, Kamide, Kei, Kurtz, Theodore W, Rakugi, Hiromi

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OS 15-09 DOES ACE2-ANGIOTENSIN-(1–7) AXIS PROTECT FROM AGING-ASSOCIATED LOSS OF SKELETAL MUSCLE FUNCTION? von Takeshita, Hikari, Takeda, Masao, Yamamoto, Koichi, Rakugi, Hiromi

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Angiotensin 1-7 alleviates aging-associated muscle weakness and bone loss, but is not associated with accelerated aging in ACE2-knockout mice von Nozato, Satoko, Yamamoto, Koichi, Takeshita, Hikari, Nozato, Yoichi, Imaizumi, Yuki, Fujimoto, Taku, Yokoyama, Serina, Nagasawa, Motonori, Takeda, Masao, Hongyo, Kazuhiro, Akasaka, Hiroshi, Takami, Yoichi, Takeya, Yasushi, Sugimoto, Ken, Mogi, Masaki, Horiuchi, Masatsugu, Rakugi, Hiromi

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Response to comment on: Takeda et al. Loss of ACE2 exaggerates high-calorie diet-induced insulin resistance by reduction of GLUT4 in mice. Diabetes 2013;62:223-233 von Yamamoto, Koichi, Takeda, Masao, Ohishi, Mitsuru, Rakugi, Hiromi

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