Activator or inhibitor? GSK-3 as a new drug target von Takahashi-Yanaga, Fumi

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Targeting Wnt signaling: can we safely eradicate cancer stem cells? von Takahashi-Yanaga, Fumi, Kahn, Michael

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DIF-1 inhibits growth and metastasis of triple-negative breast cancer through AMPK-mediated inhibition of the mTORC1-S6K signaling pathway von Seto-Tetsuo, Fumi, Arioka, Masaki, Miura, Koichi, Inoue, Takeru, Igawa, Kazunobu, Tomooka, Katsuhiko, Takahashi-Yanaga, Fumi, Sasaguri, Toshiyuki

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Differentiation‐inducing factor‐1 suppresses cyclin D1‐induced cell proliferation of MCF‐7 breast cancer cells by inhibiting S6K‐mediated signal transducer and activator of transcr... von Tetsuo, Fumi, Arioka, Masaki, Miura, Koichi, Kai, Misato, Kubo, Momoko, Igawa, Kazunobu, Tomooka, Katsuhiko, Takahashi‐Yanaga, Fumi, Nishimura, Fusanori, Sasaguri, Toshiyuki

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Celecoxib and 2,5‐dimethylcelecoxib inhibit intestinal cancer growth by suppressing the Wnt/β‐catenin signaling pathway von Egashira, Issei, Takahashi‐Yanaga, Fumi, Nishida, Risa, Arioka, Masaki, Igawa, Kazunobu, Tomooka, Katsuhiko, Nakatsu, Yoshimichi, Tsuzuki, Teruhisa, Nakabeppu, Yusaku, Kitazono, Takanari, Sasaguri, Toshiyuki

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The Wnt/β-Catenin Signaling Pathway as a Target in Drug Discovery von Takahashi-Yanaga, Fumi, Sasaguri, Toshiyuki

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Celecoxib inhibits osteoblast maturation by suppressing the expression of Wnt target genes von Nagano, Akihiro, Arioka, Masaki, Takahashi-Yanaga, Fumi, Matsuzaki, Etsuko, Sasaguri, Toshiyuki

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Drug Development Targeting the Glycogen Synthase Kinase-3β (GSK-3β)-Mediated Signal Transduction Pathway: Inhibitors of the Wnt/β-Catenin Signaling Pathway as Novel Anticancer Drug... von Takahashi-Yanaga, Fumi, Sasaguri, Toshiyuki

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Synthesis of Substituted 3(2H)‑Furanones Using Alkylative Intramolecular Cyclization of Sulfonium Salts von Inagaki, Sho, Ukaku, Mika, Chiba, Akira, Takahashi, Fumi, Yoshimi, Yasuharu, Morita, Toshio, Kawano, Tomikazu

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Influence of genetic polymorphisms and habitual caffeine intake on the changes in blood pressure, pulse rate, and calculation speed after caffeine intake: A prospective, double bli... von Yoshihara, Tatsuya, Zaitsu, Masayoshi, Shiraishi, Fumie, Arima, Hisatomi, Takahashi-Yanaga, Fumi, Arioka, Masaki, Kajioka, Shunichi, Sasaguri, Toshiyuki

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Differences in the sequence of PlcR transcriptional regulator–binding site affect sphingomyelinase production in Bacillus cereus von Yokotani, Atsushi, Takahashi, Fumi, Aoyama, Ryoko, Kamoshida, Go, Kosaka, Tadashi, Nakanishi, Masaki, Fujita, Naohisa

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Differentiation-inducing factor-1 potentiates adipogenic differentiation and attenuates the osteogenic differentiation of bone marrow-derived mesenchymal stem cells von Ishikane, Shin, Ikushima, Eigo, Igawa, Kazunobu, Tomooka, Katsuhiko, Takahashi-Yanaga, Fumi

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Anti-tumor effects of differentiation-inducing factor-1 in malignant melanoma: GSK-3-mediated inhibition of cell proliferation and GSK-3-independent suppression of cell migration a... von Arioka, Masaki, Takahashi-Yanaga, Fumi, Kubo, Momoko, Igawa, Kazunobu, Tomooka, Katsuhiko, Sasaguri, Toshiyuki

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Sphingosine-1-phosphate-enhanced Wnt5a promotes osteogenic differentiation in C3H10T1/2 cells von Hashimoto, Yoko, Kobayashi, Mari, Matsuzaki, Etsuko, Higashi, Katsumasa, Takahashi-Yanaga, Fumi, Takano, Aiko, Hirata, Masato, Nishimura, Fusanori

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2,5-Dimethylcelecoxib prevents isoprenaline-induced cardiomyocyte hypertrophy and cardiac fibroblast activation by inhibiting Akt-mediated GSK-3 phosphorylation von Morishige, Shoji, Takahashi-Yanaga, Fumi, Ishikane, Shin, Arioka, Masaki, Igawa, Kazunobu, Kuroo, Akihiro, Tomooka, Katsuhiko, Shiose, Akira, Sasaguri, Toshiyuki

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Acceleration of bone regeneration by local application of lithium: Wnt signal-mediated osteoblastogenesis and Wnt signal-independent suppression of osteoclastogenesis von Arioka, Masaki, Takahashi-Yanaga, Fumi, Sasaki, Masanori, Yoshihara, Tatsuya, Morimoto, Sachio, Hirata, Masato, Mori, Yoshihide, Sasaguri, Toshiyuki

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Antimicrobial Activity of the Constituents of Dalbergia tonkinensis and Structural-Bioactive Highlights von Son, Ninh The, Oda, Masataka, Hayashi, Naoki, Yamaguchi, Daiki, Kawagishi, Yu, Takahashi, Fumi, Harada, Kenichi, Cuong, Nguyen Manh, Fukuyama, Yoshiyasu

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Sphingosine-1-phosphate/S1PR2-mediated signaling triggers Smad1/5/8 phosphorylation and thereby induces Runx2 expression in osteoblasts von Higashi, Katsumasa, Matsuzaki, Etsuko, Hashimoto, Yoko, Takahashi-Yanaga, Fumi, Takano, Aiko, Anan, Hisashi, Hirata, Masato, Nishimura, Fusanori

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Biological actions of green tea catechins on cardiac troponin C von Tadano, Naoto, Du, Cheng‐Kun, Yumoto, Fumiaki, Morimoto, Sachio, Ohta, Mika, Xie, Ming‐Fang, Nagata, Koji, Zhan, Dong‐Yun, Lu, Qun‐Wei, Miwa, Yoshikazu, Takahashi‐Yanaga, Fumi, Tanokura, Masaru, Ohtsuki, Iwao, Sasaguri, Toshiyuki

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Oxaliplatin induces mitotic catastrophe and apoptosis in esophageal cancer cells von Ngan, Chew Yee, Yamamoto, Hirofumi, Takagi, Akimitsu, Fujie, Yujiro, Takemasa, Ichiro, Ikeda, Masataka, Takahashi‐Yanaga, Fumi, Sasaguri, Toshiyuki, Sekimoto, Mitsugu, Matsuura, Nariaki, Monden, Morito

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