Epigenetic traits inscribed in chromatin accessibility in aged hematopoietic stem cells von Itokawa, Naoki, Oshima, Motohiko, Koide, Shuhei, Takayama, Naoya, Kuribayashi, Wakako, Nakajima-Takagi, Yaeko, Aoyama, Kazumasa, Yamazaki, Satoshi, Yamaguchi, Kiyoshi, Furukawa, Yoichi, Eto, Koji, Iwama, Atsushi

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Akt inhibition synergizes with polycomb repressive complex 2 inhibition in the treatment of multiple myeloma von Rizk, Mohamed, Rizq, Ola, Oshima, Motohiko, Nakajima‐Takagi, Yaeko, Koide, Shuhei, Saraya, Atsunori, Isshiki, Yusuke, Chiba, Tetsuhiro, Yamazaki, Satoshi, Ma, Anqi, Jin, Jian, Iwama, Atsushi, Mimura, Naoya

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Dual Inhibition of EZH2 and EZH1 Sensitizes PRC2-Dependent Tumors to Proteasome Inhibition von Rizq, Ola, Mimura, Naoya, Oshima, Motohiko, Saraya, Atsunori, Koide, Shuhei, Kato, Yuko, Aoyama, Kazumasa, Nakajima-Takagi, Yaeko, Wang, Changshan, Chiba, Tetsuhiro, Ma, Anqi, Jin, Jian, Iseki, Tohru, Nakaseko, Chiaki, Iwama, Atsushi

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Heme‐mediated inhibition of Bach1 regulates the liver specificity and transience of the Nrf2‐dependent induction of zebrafish heme oxygenase 1 von Fuse, Yuji, Nakajima, Hitomi, Nakajima‐Takagi, Yaeko, Nakajima, Osamu, Kobayashi, Makoto

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Efficacy of the novel tubulin polymerization inhibitor PTC‐028 for myelodysplastic syndrome von Zhong, Cheng, Kayamori, Kensuke, Koide, Shuhei, Shinoda, Daisuke, Oshima, Motohiko, Nakajima‐Takagi, Yaeko, Nagai, Yurie, Mimura, Naoya, Sakaida, Emiko, Yamazaki, Satoshi, Iwano, Satoshi, Miyawaki, Atsushi, Ito, Ryoji, Tohyama, Kaoru, Yamaguchi, Kiyoshi, Furukawa, Yoichi, Lennox, William, Sheedy, Josephine, Weetall, Marla, Iwama, Atsushi

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Internal deletion of BCOR reveals a tumor suppressor function for BCOR in T lymphocyte malignancies von Tanaka, Tomoyuki, Nakajima-Takagi, Yaeko, Aoyama, Kazumasa, Tara, Shiro, Oshima, Motohiko, Saraya, Atsunori, Koide, Shuhei, Si, Sha, Manabe, Ichiro, Sanada, Masashi, Nakayama, Manabu, Masuko, Masayoshi, Sone, Hirohito, Koseki, Haruhiko, Iwama, Atsushi

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Polycomb repressive complex 1.1 coordinates homeostatic and emergency myelopoiesis von Nakajima-Takagi, Yaeko, Oshima, Motohiko, Takano, Junichiro, Koide, Shuhei, Itokawa, Naoki, Uemura, Shun, Yamashita, Masayuki, Andoh, Shohei, Aoyama, Kazumasa, Isshiki, Yusuke, Shinoda, Daisuke, Saraya, Atsunori, Arai, Fumio, Yamaguchi, Kiyoshi, Furukawa, Yoichi, Koseki, Haruhiko, Ikawa, Tomokatsu, Iwama, Atsushi

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Gut Microbiota Promotes Obesity-Associated Liver Cancer through PGE2-Mediated Suppression of Antitumor Immunity von Loo, Tze Mun, Kamachi, Fumitaka, Watanabe, Yoshihiro, Yoshimoto, Shin, Kanda, Hiroaki, Arai, Yuriko, Nakajima-Takagi, Yaeko, Iwama, Atsushi, Koga, Tomoaki, Sugimoto, Yukihiko, Ozawa, Takayuki, Nakamura, Masaru, Kumagai, Miho, Watashi, Koichi, Taketo, Makoto M., Aoki, Tomohiro, Narumiya, Shuh, Oshima, Masanobu, Arita, Makoto, Hara, Eiji, Ohtani, Naoko

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Insufficiency of non-canonical PRC1 synergizes with JAK2V617F in the development of myelofibrosis von Shinoda, Daisuke, Nakajima-Takagi, Yaeko, Oshima, Motohiko, Koide, Shuhei, Aoyama, Kazumasa, Saraya, Atsunori, Harada, Hironori, Rahmutulla, Bahityar, Kaneda, Atsushi, Yamaguchi, Kiyoshi, Furukawa, Yoichi, Koseki, Haruhiko, Shimoda, Kazuya, Tanaka, Tomoaki, Sashida, Goro, Iwama, Atsushi

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Limited rejuvenation of aged hematopoietic stem cells in young bone marrow niche von Kuribayashi, Wakako, Oshima, Motohiko, Itokawa, Naoki, Koide, Shuhei, Nakajima-Takagi, Yaeko, Yamashita, Masayuki, Yamazaki, Satoshi, Rahmutulla, Bahityar, Miura, Fumihito, Ito, Takashi, Kaneda, Atsushi, Iwama, Atsushi

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The combination of the tubulin binding small molecule PTC596 and proteasome inhibitors suppresses the growth of myeloma cells von Nagai, Yurie, Mimura, Naoya, Rizq, Ola, Isshiki, Yusuke, Oshima, Motohiko, Rizk, Mohamed, Saraya, Atsunori, Koide, Shuhei, Nakajima-Takagi, Yaeko, Miyota, Makiko, Chiba, Tetsuhiro, Oshima-Hasegawa, Nagisa, Muto, Tomoya, Tsukamoto, Shokichi, Mitsukawa, Shio, Takeda, Yusuke, Ohwada, Chikako, Takeuchi, Masahiro, Iseki, Tohru, Nakaseko, Chiaki, Lennox, William, Sheedy, Josephine, Weetall, Marla, Yokote, Koutaro, Iwama, Atsushi, Sakaida, Emiko

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PRC2 insufficiency causes p53-dependent dyserythropoiesis in myelodysplastic syndrome von Aoyama, Kazumasa, Shinoda, Daisuke, Suzuki, Emi, Nakajima-Takagi, Yaeko, Oshima, Motohiko, Koide, Shuhei, Rizq, Ola, Si, Sha, Tara, Shiro, Sashida, Goro, Iwama, Atsushi

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The Antioxidant Defense System Keap1-Nrf2 Comprises a Multiple Sensing Mechanism for Responding to a Wide Range of Chemical Compounds von Kobayashi, Makoto, Li, Li, Iwamoto, Noriko, Nakajima-Takagi, Yaeko, Kaneko, Hiroshi, Nakayama, Yuko, Eguchi, Masami, Wada, Yoshiko, Kumagai, Yoshito, Yamamoto, Masayuki

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Nitro‐fatty acids and cyclopentenone prostaglandins share strategies to activate the Keap1‐Nrf2 system: a study using green fluorescent protein transgenic zebrafish von Tsujita, Tadayuki, Li, Li, Nakajima, Hitomi, Iwamoto, Noriko, Nakajima‐Takagi, Yaeko, Ohashi, Ken, Kawakami, Koichi, Kumagai, Yoshito, Freeman, Bruce A., Yamamoto, Masayuki, Kobayashi, Makoto

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Nrf2 activation attenuates genetic endoplasmic reticulum stress induced by a mutation in the phosphomannomutase 2 gene in zebrafish von Mukaigasa, Katsuki, Tsujita, Tadayuki, Nguyen, Vu Thanh, Li, Li, Yagi, Hirokazu, Fuse, Yuji, Nakajima-Takagi, Yaeko, Kato, Koichi, Yamamoto, Masayuki, Kobayashi, Makoto

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Noncanonical EZH2 drives retinoic acid resistance of variant acute promyelocytic leukemias von Poplineau, Mathilde, Platet, Nadine, Mazuel, Adrien, Hérault, Léonard, N’Guyen, Lia, Koide, Shuhei, Nakajima-Takagi, Yaeko, Kuribayashi, Wakako, Carbuccia, Nadine, Haboub, Loreen, Vernerey, Julien, Oshima, Motohiko, Birnbaum, Daniel, Iwama, Atsushi, Duprez, Estelle

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Bcor insufficiency promotes initiation and progression of myelodysplastic syndrome von Tara, Shiro, Isshiki, Yusuke, Nakajima-Takagi, Yaeko, Oshima, Motohiko, Aoyama, Kazumasa, Tanaka, Tomoyuki, Shinoda, Daisuke, Koide, Shuhei, Saraya, Atsunori, Miyagi, Satoru, Manabe, Ichiro, Matsui, Hirotaka, Koseki, Haruhiko, Bardwell, Vivian J., Iwama, Atsushi

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The chromatin-binding protein Phf6 restricts the self-renewal of hematopoietic stem cells von Miyagi, Satoru, Sroczynska, Patrycja, Kato, Yuko, Nakajima-Takagi, Yaeko, Oshima, Motohiko, Rizq, Ola, Takayama, Naoya, Saraya, Atsunori, Mizuno, Seiya, Sugiyama, Fumihiro, Takahashi, Satoru, Matsuzaki, Yumi, Christensen, Jesper, Helin, Kristian, Iwama, Atsushi

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Role of SOX17 in hematopoietic development from human embryonic stem cells von Nakajima-Takagi, Yaeko, Osawa, Mitsujiro, Oshima, Motohiko, Takagi, Haruna, Miyagi, Satoru, Endoh, Mitsuhiro, Endo, Takaho A., Takayama, Naoya, Eto, Koji, Toyoda, Tetsuro, Koseki, Haruhiko, Nakauchi, Hiromitsu, Iwama, Atsushi

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Setdb1 maintains hematopoietic stem and progenitor cells by restricting the ectopic activation of nonhematopoietic genes von Koide, Shuhei, Oshima, Motohiko, Takubo, Keiyo, Yamazaki, Satoshi, Nitta, Eriko, Saraya, Atsunori, Aoyama, Kazumasa, Kato, Yuko, Miyagi, Satoru, Nakajima-Takagi, Yaeko, Chiba, Tetsuhiro, Matsui, Hirotaka, Arai, Fumio, Suzuki, Yutaka, Kimura, Hiroshi, Nakauchi, Hiromitsu, Suda, Toshio, Shinkai, Yoichi, Iwama, Atsushi

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