Basis of CTLA-4 function in regulatory and conventional CD4+ T cells von Tai, Xuguang, Van Laethem, François, Pobezinsky, Leonid, Guinter, Terry, Sharrow, Susan O., Adams, Anthony, Granger, Larry, Kruhlak, Michael, Lindsten, Tullia, Thompson, Craig B., Feigenbaum, Lionel, Singer, Alfred

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New insights into developmental fate decisions by autoreactive CD4 thymocytes von Tai, Xuguang, Singer, Alfred

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Editorial: Revisit the roles of regulatory T cells in infection von Zhou, Xuyu, Zhao, Jingxian, Li, Bin, Tai, Xuguang

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Unveiling the gut microbiota blueprint of schizophrenia: a multilevel omics approach von Qi, DongDong, Liu, Peng, Wang, YiMeng, Tai, XuGuang, Ma, ShiFa

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Timing and duration of MHC I positive selection signals are adjusted in the thymus to prevent lineage errors von Kimura, Motoko Y, Thomas, Julien, Tai, Xuguang, Guinter, Terry I, Shinzawa, Miho, Etzensperger, Ruth, Li, Zhenhu, Love, Paul, Nakayama, Toshinori, Singer, Alfred

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MCL-1 keeps a charming home for thymocytes von Tai, Xuguang

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Immature CD8 Single-Positive Thymocytes Are a Molecularly Distinct Subpopulation, Selectively Dependent on BRD4 for Their Differentiation von Gegonne, Anne, Chen, Qing-Rong, Dey, Anup, Etzensperger, Ruth, Tai, Xuguang, Singer, Alfred, Meerzaman, Daoud, Ozato, Keiko, Singer, Dinah S.

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The small intestine epithelium exempts Foxp3+ Tregs from their IL-2 requirement for homeostasis and effector function von Prakhar, Praveen, Alvarez-DelValle, Jaylene, Keller, Hilary, Crossman, Assiatu, Tai, Xuguang, Park, Yoo Kyoung, Park, Jung-Hyun

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Induction of autoimmune disease in CTLA-4⁻/⁻ mice depends on a specific CD28 motif that is required for in vivo costimulation von Tai, Xuguang, Van Laethem, Francois, Sharpe, Arlene H, Singer, Alfred

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Novel MHC-Independent αβTCRs Specific for CD48, CD102, and CD155 Self-Proteins and Their Selection in the Thymus von Van Laethem, François, Saba, Ingrid, Lu, Jinghua, Bhattacharya, Abhisek, Tai, Xuguang, Guinter, Terry I, Engelhardt, Britta, Alag, Amala, Rojano, Mirelle, Ashe, Jennifer M, Hanada, Ken-Ichi, Yang, James C, Sun, Peter D, Singer, Alfred

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CD28 signaling in primary CD4(+) T cells: identification of both tyrosine phosphorylation-dependent and phosphorylation-independent pathways von Ogawa, Shuhei, Watanabe, Masashi, Sakurai, Yuichi, Inutake, Yu, Watanabe, Shiho, Tai, Xuguang, Abe, Ryo

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The General Transcription Factor TAF7 Is Essential for Embryonic Development but Not Essential for the Survival or Differentiation of Mature T Cells von Gegonne, Anne, Tai, Xuguang, Zhang, Jinghui, Wu, Gang, Zhu, Jianjian, Yoshimoto, Aki, Hanson, Jeffrey, Cultraro, Constance, Chen, Qing-Rong, Guinter, Terry, Yang, Zhihui, Hathcock, Karen, Singer, Alfred, Rodriguez-Canales, Jaime, Tessarollo, Lino, Mackem, Susan, Meerzaman, Daoud, Buetow, Ken, Singer, Dinah S.

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The Cytokine Receptor IL-7Rα Impairs IL-2 Receptor Signaling and Constrains the In Vitro Differentiation of Foxp3+ Treg Cells von Waickman, Adam T., Keller, Hilary R., Kim, Tae-Hyoun, Luckey, Megan A., Tai, Xuguang, Hong, Changwan, Molina-París, Carmen, Walsh, Scott T.R., Park, Jung-Hyun

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Response to RAG-Mediated V(D)J Cleavage by NBS1 and γ-H2AX von Chen, Hua Tang, Bhandoola, Avinash, Difilippantonio, Michael J., Zhu, Jie, Brown, Martin J., Tai, Xuguang, Rogakou, Emmy P., Brotz, Tilmann M., Bonner, William M., Ried, Thomas, Nussenzweig, André

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CD8 T cell tolerance results from eviction of immature autoreactive cells from the thymus von Badr, Mohamed Elsherif, Zhang, Zhongmei, Tai, Xuguang, Singer, Alfred

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Basis of Treg development in the thymus von Tai, Xuguang, Singer, Alfred

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Glutamine-dependent α-ketoglutarate production regulates the balance between T helper 1 cell and regulatory T cell generation von Klysz, Dorota, Tai, Xuguang, Robert, Philippe A, Craveiro, Marco, Cretenet, Gaspard, Oburoglu, Leal, Mongellaz, Cédric, Floess, Stefan, Fritz, Vanessa, Matias, Maria I, Yong, Carmen, Surh, Natalie, Marie, Julien C, Huehn, Jochen, Zimmermann, Valérie, Kinet, Sandrina, Dardalhon, Valérie, Taylor, Naomi

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Foxp3 Transcription Factor Is Proapoptotic and Lethal to Developing Regulatory T Cells unless Counterbalanced by Cytokine Survival Signals von Tai, Xuguang, Erman, Batu, Alag, Amala, Mu, Jie, Kimura, Motoko, Katz, Gil, Guinter, Terry, McCaughtry, Tom, Etzensperger, Ruth, Feigenbaum, Lionel, Singer, Dinah S., Singer, Alfred

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The requirement for pre-TCR during thymic differentiation enforces a developmental pause that is essential for V-DJβ rearrangement von Hathcock, Karen S, Farrington, Lila, Ivanova, Irina, Livak, Ferenc, Selimyan, Roza, Sen, Ranjan, Williams, Joy, Tai, Xuguang, Hodes, Richard J

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How autoreactive thymocytes differentiate into regulatory versus effector CD4+ T cells after avoiding clonal deletion von Tai, Xuguang, Indart, Alyssa, Rojano, Mirelle, Guo, Jie, Apenes, Nicolai, Kadakia, Tejas, Craveiro, Marco, Alag, Amala, Etzensperger, Ruth, Badr, Mohamed Elsherif, Zhang, Flora, Zhang, Zhongmei, Mu, Jie, Guinter, Terry, Crossman, Assiatu, Granger, Larry, Sharrow, Susan, Zhou, Xuyu, Singer, Alfred

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