The impact of oxidative stress and inflammation on RPE degeneration in non-neovascular AMD von Datta, Sayantan, Cano, Marisol, Ebrahimi, Katayoon, Wang, Lei, Handa, James T.

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How does the macula protect itself from oxidative stress? von Handa, James T.

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A systems biology approach towards understanding and treating non-neovascular age-related macular degeneration von Handa, James T., Bowes Rickman, Cathy, Dick, Andrew D., Gorin, Michael B., Miller, Joan W., Toth, Cynthia A., Ueffing, Marius, Zarbin, Marco, Farrer, Lindsay A.

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Nrf2 signaling is impaired in the aging RPE given an oxidative insult von Sachdeva, Mira M., Cano, Marisol, Handa, James T.

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The impact of lipids, lipid oxidation, and inflammation on AMD, and the potential role of miRNAs on lipid metabolism in the RPE von Jun, Sujung, Datta, Sayantan, Wang, Lei, Pegany, Roma, Cano, Marisol, Handa, James T.

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ATAC-Seq analysis reveals a widespread decrease of chromatin accessibility in age-related macular degeneration von Wang, Jie, Zibetti, Cristina, Shang, Peng, Sripathi, Srinivasa R., Zhang, Pingwu, Cano, Marisol, Hoang, Thanh, Xia, Shuli, Ji, Hongkai, Merbs, Shannath L., Zack, Donald J., Handa, James T., Sinha, Debasish, Blackshaw, Seth, Qian, Jiang

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Decreased membrane complement regulators in the retinal pigmented epithelium contributes to age-related macular degeneration von Ebrahimi, Katayoon B, Fijalkowski, Natalia, Cano, Marisol, Handa, James T

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Complement factor H binds malondialdehyde epitopes and protects from oxidative stress von Weismann, David, Hartvigsen, Karsten, Lauer, Nadine, Bennett, Keiryn L., Scholl, Hendrik P. N., Issa, Peter Charbel, Cano, Marisol, Brandstätter, Hubert, Tsimikas, Sotirios, Skerka, Christine, Superti-Furga, Giulio, Handa, James T., Zipfel, Peter F., Witztum, Joseph L., Binder, Christoph J.

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Quantifying the Rate of Ellipsoid Zone Loss in Stargardt Disease von Cai, Cindy X., Light, Jacob G., Handa, James T.

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Distribution, ecology, and adaptation to salinity stress of wild Hydrangea macrophylla endemic to Japan von Morimoto, H., Harada, S., Shukuya, S., Yamamoto, S., Handa, T.

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Altered profiles of intestinal microbiota and organic acids may be the origin of symptoms in irritable bowel syndrome von Tana, C., Umesaki, Y., Imaoka, A., Handa, T., Kanazawa, M., Fukudo, S.

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Photic generation of 11-cis-retinal in bovine retinal pigment epithelium von Zhang, Jianye, Choi, Elliot H., Tworak, Aleksander, Salom, David, Leinonen, Henri, Sander, Christopher L., Hoang, Thanh V., Handa, James T., Blackshaw, Seth, Palczewska, Grazyna, Kiser, Philip D., Palczewski, Krzysztof

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NRF2 plays a protective role in diabetic retinopathy in mice von Xu, Zhenhua, Wei, Yanhong, Gong, Junsong, Cho, Hongkwan, Park, James K., Sung, Ee-Rah, Huang, Hu, Wu, Lijuan, Eberhart, Charles, Handa, James T., Du, Yunpeng, Kern, Timothy S., Thimmulappa, Rajesh, Barber, Alistair J., Biswal, Shyam, Duh, Elia J.

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Chronic cigarette smoke causes oxidative damage and apoptosis to retinal pigmented epithelial cells in mice von Fujihara, Masashi, Nagai, Norihiro, Sussan, Thomas E, Biswal, Shyam, Handa, James T

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Reward-modulated motor information in identified striatum neurons von Isomura, Yoshikazu, Takekawa, Takashi, Harukuni, Rie, Handa, Takashi, Aizawa, Hidenori, Takada, Masahiko, Fukai, Tomoki

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An easy, rapid method to isolate RPE cell protein from the mouse eye von Wei, Hong, Xun, Zixian, Granado, Herta, Wu, Angela, Handa, James T.

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Hypoxic retinal Müller cells promote vascular permeability by HIF-1–dependent up-regulation of angiopoietin-like 4 von Xin, Xiaoban, Rodrigues, Murilo, Umapathi, Mahaa, Kashiwabuchi, Fabiana, Ma, Tao, Babapoor-Farrokhran, Savalan, Wang, Shuang, Hu, Jiadi, Bhutto, Imran, Welsbie, Derek S, Duh, Elia J, Handa, James T, Eberhart, Charles G, Lutty, Gerard, Semenza, Gregg L, Montaner, Silvia, Sodhi, Akrit

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Lysosomes: Regulators of autophagy in the retinal pigmented epithelium von Sinha, Debasish, Valapala, Mallika, Shang, Peng, Hose, Stacey, Grebe, Rhonda, Lutty, Gerard A., Zigler, J. Samuel, Kaarniranta, Kai, Handa, James T.

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Reducing Akt2 in retinal pigment epithelial cells causes a compensatory increase in Akt1 and attenuates diabetic retinopathy von Liu, Haitao, Stepicheva, Nadezda A., Ghosh, Sayan, Shang, Peng, Chowdhury, Olivia, Daley, Rachel A., Yazdankhah, Meysam, Gupta, Urvi, Hose, Stacey L., Valapala, Mallika, Fitting, Christopher Scott, Strizhakova, Anastasia, Shan, Yang, Feenstra, Derrick, Sahel, José-Alain, Jayagopal, Ashwath, Handa, James T., Zigler, J. Samuel, Fort, Patrice E., Sodhi, Akrit, Sinha, Debasish

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Aqueous proteins help predict the response of patients with neovascular age-related macular degeneration to anti-VEGF therapy von Cao, Xuan, Sanchez, Jaron Castillo, Dinabandhu, Aumreetam, Guo, Chuanyu, Patel, Tapan P, Yang, Zhiyong, Hu, Ming-Wen, Chen, Lijun, Wang, Yuefan, Malik, Danyal, Jee, Kathleen, Daoud, Yassine J, Handa, James T, Zhang, Hui, Qian, Jiang, Montaner, Silvia, Sodhi, Akrit

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