SHIP1, but not an AML-derived SHIP1 mutant, suppresses myeloid leukemia growth in a xenotransplantation mouse model von Täger, M, Horn, S, Latuske, E, Ehm, P, Schaks, M, Nalaskowski, M, Fehse, B, Fiedler, W, Stocking, C, Wellbrock, J, Jücker, M

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Preclinical pilot study monitoring topical drug penetration and dermal bioavailability of a peptidase inhibitor from different galenic formulations into pig dermis, using cutaneous... von Quist, S. R., Heimburg, A., Bank, U., Mahnkopf, D., Koch, G., Gollnick, H., Täger, M., Ansorge, S.

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Fibrosis of two: Epithelial cell-fibroblast interactions in pulmonary fibrosis von Sakai, Norihiko, Tager, Andrew M.

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Efficient Ablation of Genes in Human Hematopoietic Stem and Effector Cells using CRISPR/Cas9 von Mandal, Pankaj K., Ferreira, Leonardo M.R., Collins, Ryan, Meissner, Torsten B., Boutwell, Christian L., Friesen, Max, Vrbanac, Vladimir, Garrison, Brian S., Stortchevoi, Alexei, Bryder, David, Musunuru, Kiran, Brand, Harrison, Tager, Andrew M., Allen, Todd M., Talkowski, Michael E., Rossi, Derrick J., Cowan, Chad A.

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New therapeutic targets in idiopathic pulmonary fibrosis. Aiming to rein in runaway wound-healing responses von Ahluwalia, Neil, Shea, Barry S, Tager, Andrew M

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The Rho kinases: critical mediators of multiple profibrotic processes and rational targets for new therapies for pulmonary fibrosis von Knipe, Rachel S, Tager, Andrew M, Liao, James K

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Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis von Liu, Fei, Lagares, David, Choi, Kyoung Moo, Stopfer, Lauren, Marinković, Aleksandar, Vrbanac, Vladimir, Probst, Clemens K, Hiemer, Samantha E, Sisson, Thomas H, Horowitz, Jeffrey C, Rosas, Ivan O, Fredenburgh, Laura E, Feghali-Bostwick, Carol, Varelas, Xaralabos, Tager, Andrew M, Tschumperlin, Daniel J

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Humoral Immunity in Humanized Mice: A Work in Progress von Seung, Edward, Tager, Andrew M.

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An Official American Thoracic Society Workshop Report: Use of Animal Models for the Preclinical Assessment of Potential Therapies for Pulmonary Fibrosis von Jenkins, R Gisli, Moore, Bethany B, Chambers, Rachel C, Eickelberg, Oliver, Königshoff, Melanie, Kolb, Martin, Laurent, Geoffrey J, Nanthakumar, Carmel B, Olman, Mitchell A, Pardo, Annie, Selman, Moises, Sheppard, Dean, Sime, Patricia J, Tager, Andrew M, Tatler, Amanda L, Thannickal, Victor J, White, Eric S

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Feedback amplification of fibrosis through matrix stiffening and COX-2 suppression von Liu, Fei, Mih, Justin D, Shea, Barry S, Kho, Alvin T, Sharif, Asma S, Tager, Andrew M, Tschumperlin, Daniel J

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PD-1 blockade in chronically HIV-1-infected humanized mice suppresses viral loads von Seung, Edward, Dudek, Timothy E, Allen, Todd M, Freeman, Gordon J, Luster, Andrew D, Tager, Andrew M

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LPA1‐induced cytoskeleton reorganization drives fibrosis through CTGF‐dependent fibroblast proliferation von Sakai, Norihiko, Chun, Jerold, Duffield, Jeremy S., Wada, Takashi, Luster, Andrew D., Tager, Andrew M.

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An Autotaxin/Lysophosphatidic Acid/Interleukin‐6 Amplification Loop Drives Scleroderma Fibrosis von Castelino, Flavia V., Bain, Gretchen, Pace, Veronica A., Black, Katharine E., George, Leaya, Probst, Clemens K., Goulet, Lance, Lafyatis, Robert, Tager, Andrew M.

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The Rho Kinase Isoforms ROCK1 and ROCK2 Each Contribute to the Development of Experimental Pulmonary Fibrosis von Knipe, Rachel S, Probst, Clemens K, Lagares, David, Franklin, Alicia, Spinney, Jillian J, Brazee, Patricia L, Grasberger, Paula, Zhang, Linlin, Black, Katharine E, Sakai, Norihiko, Shea, Barry S, Liao, James K, Medoff, Benjamin D, Tager, Andrew M

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Glycerol-3-phosphate is an FGF23 regulator derived from the injured kidney von Simic, Petra, Kim, Wondong, Zhou, Wen, Pierce, Kerry A, Chang, Wenhan, Sykes, David B, Aziz, Najihah B, Elmariah, Sammy, Ngo, Debby, Pajevic, Paola Divieti, Govea, Nicolas, Kestenbaum, Bryan R, de Boer, Ian H, Cheng, Zhiqiang, Christov, Marta, Chun, Jerold, Leaf, David E, Waikar, Sushrut S, Tager, Andrew M, Gerszten, Robert E, Thadhani, Ravi I, Clish, Clary B, Jüppner, Harald, Wein, Marc N, Rhee, Eugene P

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Specialized transendothelial dendritic cells mediate thymic T-cell selection against blood-borne macromolecules von Vollmann, Elisabeth H., Rattay, Kristin, Barreiro, Olga, Thiriot, Aude, Fuhlbrigge, Rebecca A., Vrbanac, Vladimir, Kim, Ki-Wook, Jung, Steffen, Tager, Andrew M., von Andrian, Ulrich H.

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Graft versus host disease in the bone marrow, liver and thymus humanized mouse model von Greenblatt, Matthew B, Vrbanac, Vladimir, Vbranac, Vladimir, Tivey, Trevor, Tsang, Kelly, Tager, Andrew M, Aliprantis, Antonios O

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Lysophosphatidic acid signaling through its receptor initiates profibrotic epithelial cell fibroblast communication mediated by epithelial cell derived connective tissue growth fac... von Sakai, Norihiko, Chun, Jerold, Duffield, Jeremy S., Lagares, David, Wada, Takashi, Luster, Andrew D., Tager, Andrew M.

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Inhibition of HIV transmission in human cervicovaginal explants and humanized mice using CD4 aptamer-siRNA chimeras von Wheeler, Lee Adam, Trifonova, Radiana, Vrbanac, Vladimir, Basar, Emre, McKernan, Shannon, Xu, Zhan, Seung, Edward, Deruaz, Maud, Dudek, Tim, Einarsson, Jon Ivar, Yang, Linda, Allen, Todd M, Luster, Andrew D, Tager, Andrew M, Dykxhoorn, Derek M, Lieberman, Judy

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The lysophosphatidic acid receptor LPA1 links pulmonary fibrosis to lung injury by mediating fibroblast recruitment and vascular leak von Tager, Andrew M, LaCamera, Peter, Shea, Barry S, Campanella, Gabriele S, Selman, Moisés, Zhao, Zhenwen, Polosukhin, Vasiliy, Wain, John, Karimi-Shah, Banu A, Kim, Nancy D, Hart, William K, Pardo, Annie, Blackwell, Timothy S, Xu, Yan, Chun, Jerold, Luster, Andrew D

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