Thymine DNA Glycosylase Is Essential for Active DNA Demethylation by Linked Deamination-Base Excision Repair von Cortellino, Salvatore, Xu, Jinfei, Sannai, Mara, Moore, Robert, Caretti, Elena, Cigliano, Antonio, Le Coz, Madeleine, Devarajan, Karthik, Wessels, Andy, Soprano, Dianne, Abramowitz, Lara K., Bartolomei, Marisa S., Rambow, Florian, Bassi, Maria Rosaria, Bruno, Tiziana, Fanciulli, Maurizio, Renner, Catherine, Klein-Szanto, Andres J., Matsumoto, Yoshihiro, Kobi, Dominique, Davidson, Irwin, Alberti, Christophe, Larue, Lionel, Bellacosa, Alfonso

Volltext

IL-6 Mediates Cross-Talk between Tumor Cells and Activated Fibroblasts in the Tumor Microenvironment von Karakasheva, Tatiana A, Lin, Eric W, Tang, Qiaosi, Qiao, Edmund, Waldron, Todd J, Soni, Monica, Klein-Szanto, Andres J, Sahu, Varun, Basu, Devraj, Ohashi, Shinya, Baba, Kiichiro, Giaccone, Zachary T, Walker, Sarah R, Frank, David A, Wileyto, E Paul, Long, Qi, Dunagin, Margaret C, Raj, Arjun, Diehl, J Alan, Wong, K K, Bass, Adam J, Rustgi, Anil K

Volltext

Visinin-like proteins (VSNLs): interaction partners and emerging functions in signal transduction of a subfamily of neuronal Ca²⁺-sensor proteins von Braunewell, Karl-Heinz, Szanto, Andres J. Klein

Volltext

Influence of Affinity and Antigen Internalization on the Uptake and Penetration of Anti-HER2 Antibodies in Solid Tumors von RUDNICK, Stephen I, JIANLONG LOU, SHALLER, Calvin C, YONG TANG, KLEIN-SZANTO, Andres J. P, WEINER, Louis M, MARKS, James D, ADAMS, Gregory P

Volltext

p21-Activated Kinase 1 Is Required for Efficient Tumor Formation and Progression in a Ras-Mediated Skin Cancer Model von HOI YEE CHOW, JUBB, Adrian M, SILVIO GUTKIND, J, HOEFLICH, Klaus P, CHERNOFF, Jonathan, KOCH, Jennifer N, JAFFER, Zahara M, STEPANOVA, Dina, CAMPBELL, David A, DURON, Sergio G, O'FARRELL, Marie, CAI, Kathy Q, KLEIN-SZANTO, Andres J. P

Volltext

Interplay between Notch1 and Notch3 promotes EMT and tumor initiation in squamous cell carcinoma von Natsuizaka, Mitsuteru, Whelan, Kelly A., Kagawa, Shingo, Tanaka, Koji, Giroux, Veronique, Chandramouleeswaran, Prasanna M., Long, Apple, Sahu, Varun, Darling, Douglas S., Que, Jianwen, Yang, Yizeng, Katz, Jonathan P., Wileyto, E. Paul, Basu, Devraj, Kita, Yoshiaki, Natsugoe, Shoji, Naganuma, Seiji, Klein-Szanto, Andres J., Diehl, J. Alan, Bass, Adam J., Wong, Kwok-Kin, Rustgi, Anil K., Nakagawa, Hiroshi

Volltext

Rab11-FIP1 mediates epithelial-mesenchymal transition and invasion in esophageal cancer von Tang, Qiaosi, Lento, Ashley, Suzuki, Kensuke, Efe, Gizem, Karakasheva, Tatiana, Long, Apple, Giroux, Véronique, Islam, Mirazul, Wileyto, E Paul, Klein-Szanto, Andres J, Nakagawa, Hiroshi, Bass, Adam, Rustgi, Anil K

Volltext

NOTCH1 and NOTCH3 Coordinate Esophageal Squamous Differentiation Through a CSL-Dependent Transcriptional Network von Ohashi, Shinya, Natsuizaka, Mitsuteru, Yashiro–Ohtani, Yumi, Kalman, Ross A, Nakagawa, Momo, Wu, Lizi, Klein–Szanto, Andres J, Herlyn, Meenhard, Diehl, J. Alan, Katz, Jonathan P, Pear, Warren S, Seykora, John T, Nakagawa, Hiroshi

Volltext

Proprotein convertase inhibition: Paralyzing the cell’s master switches von Klein-Szanto, Andres J., Bassi, Daniel E.

Volltext

Inactivation of Tp53 and Pten drives rapid development of pleural and peritoneal malignant mesotheliomas von Sementino, Eleonora, Menges, Craig W., Kadariya, Yuwaraj, Peri, Suraj, Xu, Jinfei, Liu, Zemin, Wilkes, Richard G., Cai, Kathy Q., Rauscher, Frank J., Klein‐Szanto, Andres J., Testa, Joseph R.

Volltext

Aurora kinase A mediates epithelial ovarian cancer cell migration and adhesion von Do, T-V, Xiao, F, Bickel, L E, Klein-Szanto, A J, Pathak, H B, Hua, X, Howe, C, O'Brien, S W, Maglaty, M, Ecsedy, J A, Litwin, S, Golemis, E A, Schilder, R J, Godwin, A K, Connolly, D C

Volltext

Bap1 Is a Bona Fide Tumor Suppressor: Genetic Evidence from Mouse Models Carrying Heterozygous Germline Bap1 Mutations von Kadariya, Yuwaraj, Cheung, Mitchell, Xu, Jinfei, Pei, Jianming, Sementino, Eleonora, Menges, Craig W, Cai, Kathy Q, Rauscher, Frank J, Klein-Szanto, Andres J, Testa, Joseph R

Volltext

Dll1+ quiescent tumor stem cells drive chemoresistance in breast cancer through NF-κB survival pathway von Kumar, Sushil, Nandi, Ajeya, Singh, Snahlata, Regulapati, Rohan, Li, Ning, Tobias, John W., Siebel, Christian W., Blanco, Mario Andres, Klein-Szanto, Andres J., Lengner, Christopher, Welm, Alana L., Kang, Yibin, Chakrabarti, Rumela

Volltext

Regulation of Epithelial Plasticity Determines Metastatic Organotropism in Pancreatic Cancer von Reichert, Maximilian, Bakir, Basil, Moreira, Leticia, Pitarresi, Jason R., Feldmann, Karin, Simon, Lauren, Suzuki, Kensuke, Maddipati, Ravikanth, Rhim, Andrew D., Schlitter, Anna M., Kriegsmann, Mark, Weichert, Wilko, Wirth, Matthias, Schuck, Kathleen, Schneider, Günter, Saur, Dieter, Reynolds, Albert B., Klein-Szanto, Andres J., Pehlivanoglu, Burcin, Memis, Bahar, Adsay, N. Volkan, Rustgi, Anil K.

Volltext

Autophagy supports generation of cells with high CD44 expression via modulation of oxidative stress and Parkin-mediated mitochondrial clearance von Whelan, K A, Chandramouleeswaran, P M, Tanaka, K, Natsuizaka, M, Guha, M, Srinivasan, S, Darling, D S, Kita, Y, Natsugoe, S, Winkler, J D, Klein-Szanto, A J, Amaravadi, R K, Avadhani, N G, Rustgi, A K, Nakagawa, H

Volltext

Targeting proprotein convertases in furin‐rich lung cancer cells results in decreased in vitro and in vivo growth von Bassi, Daniel E., Zhang, Jirong, Renner, Catherine, Klein‐Szanto, Andres J.

Volltext

Generation and Characterization of Patient‐Derived Head and Neck, Oral, and Esophageal Cancer Organoids von Karakasheva, Tatiana A., Kijima, Takashi, Shimonosono, Masataka, Maekawa, Hisatsugu, Sahu, Varun, Gabre, Joel T., Cruz‐Acuña, Ricardo, Giroux, Veronique, Sangwan, Veena, Whelan, Kelly A., Natsugoe, Shoji, Yoon, Angela J., Philipone, Elizabeth, Klein‐Szanto, Andres J., Ginsberg, Gregory G., Falk, Gary W., Abrams, Julian A., Que, Jianwen, Basu, Devraj, Ferri, Lorenzo, Diehl, J. Alan, Bass, Adam J., Wang, Timothy C., Rustgi, Anil K., Nakagawa, Hiroshi

Volltext

Endogenous Sterol Metabolites Regulate Growth of EGFR/KRAS-Dependent Tumors via LXR von Gabitova, Linara, Restifo, Diana, Gorin, Andrey, Manocha, Kunal, Handorf, Elizabeth, Yang, Dong-Hua, Cai, Kathy Q., Klein-Szanto, Andres J., Cunningham, David, Kratz, Lisa E., Herman, Gail E., Golemis, Erica A., Astsaturov, Igor

Volltext

Correction to: Overexpression of the HMGA2 gene in transgenic mice leads to the onset of pituitary adenomas von Fedele, Monica, Battista, Sabrina, Kenyon, Lawrence, Baldassarre, Gustavo, Fidanza, Vincenzo, Klein-Szanto, Andres J. P., Parlow, A. F., Visone, Rosa, Pierantoni, Giovanna M., Outwater, Eric, Santoro, Massimo, Croce, Carlo M., Fusco, Alfredo

Volltext

The protein kinase Akt induces epithelial mesenchymal transition and promotes enhanced motility and invasiveness of squamous cell carcinoma lines von JULIEN GRILLE, Sylvia, BELLACOSA, Alfonso, UPSON, John, KLEIN-SZANTO, Andres J, VAN ROY, Frans, LEE-KWON, Whaseon, DONOWITZ, Mark, TSICHLIS, Philip N, LARUE, Lionel

Volltext