Safeguarding genome integrity: the checkpoint kinases ATR, CHK1 and WEE1 restrain CDK activity during normal DNA replication von Sorensen, C. S., Syljuasen, R. G.

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Hypoxia-Induced Gene Expression in Chemoradioresistant Cervical Cancer Revealed by Dynamic Contrast-Enhanced MRI von HALLE, Cathinka, ANDERSEN, Erlend, MALINEN, Eirik, LYNG, Heidi, LANDO, Malin, AARNES, Eva-Katrine, HASVOLD, Grete, HOLDEN, Marit, SYLJUASEN, Randi G, SUNDFØR, Kolbein, KRISTENSEN, Gunnar B, HOLM, Ruth

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p21 limits S phase DNA damage caused by the Wee1 inhibitor MK1775 von Hauge, Sissel, Macurek, Libor, Syljuåsen, Randi G.

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A novel, rapid and sensitive flow cytometry method reveals degradation of promoter proximal paused RNAPII in the presence and absence of UV von Bay, Lilli T E, Syljuåsen, Randi G, Landsverk, Helga B

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Adaptation to the ionizing radiation-induced G2 checkpoint occurs in human cells and depends on checkpoint kinase 1 and polo-like kinase 1 kinases von SYLJUASEN, Randi G, JENSEN, Sanne, BARTEK, Jiri, LUKAS, Jiri

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WDR82/PNUTS-PP1 Prevents Transcription-Replication Conflicts by Promoting RNA Polymerase II Degradation on Chromatin von Landsverk, Helga B., Sandquist, Lise E., Bay, Lilli T.E., Steurer, Barbara, Campsteijn, Coen, Landsverk, Ole J.B., Marteijn, Jurgen A., Petermann, Eva, Trinkle-Mulcahy, Laura, Syljuåsen, Randi G.

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Immunogenic cell death after combined treatment with radiation and ATR inhibitors is dually regulated by apoptotic caspases von Eek Mariampillai, Adrian, Hauge, Sissel, Kongsrud, Karoline, Syljuåsen, Randi G

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The cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repair von Sørensen, Claus Storgaard, Hansen, Lasse Tengbjerg, Dziegielewski, Jaroslaw, Syljuåsen, Randi G., Lundin, Cecilia, Bartek, Jiri, Helleday, Thomas

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Regulation of ATR activity via the RNA polymerase II associated factors CDC73 and PNUTS-PP1 von Landsverk, Helga B, Sandquist, Lise E, Sridhara, Sreerama C, Rødland, Gro Elise, Sabino, João C, de Almeida, Sérgio F, Grallert, Beata, Trinkle-Mulcahy, Laura, Syljuåsen, Randi G

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Potential Benefits of Combining Proton or Carbon Ion Therapy with DNA Damage Repair Inhibitors von Rødland, Gro Elise, Temelie, Mihaela, Eek Mariampillai, Adrian, Hauge, Sissel, Gilbert, Antoine, Chevalier, François, Savu, Diana I, Syljuåsen, Randi G

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Combined inhibition of Wee1 and Chk1 gives synergistic DNA damage in S-phase due to distinct regulation of CDK activity and CDC45 loading von Hauge, Sissel, Naucke, Christian, Hasvold, Grete, Joel, Mrinal, Rødland, Gro Elise, Juzenas, Petras, Stokke, Trond, Syljuåsen, Randi G

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A novel role for ATR/Rad3 in G1 phase von Bøe, Cathrine A., Håland, Tine W., Boye, Erik, Syljuåsen, Randi G., Grallert, Beáta

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Interferon signaling is enhanced by ATR inhibition in glioblastoma cells irradiated with X-rays, protons or carbon ions von Rødland, Gro Elise, Temelie, Mihaela, Eek Mariampillai, Adrian, Serban, Ana Maria, Edin, Nina Frederike Jeppesen, Malinen, Eirik, Lindbergsengen, Lilian, Gilbert, Antoine, Chevalier, François, Savu, Diana I., Syljuåsen, Randi G.

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Analysis of RNA Polymerase II Chromatin Binding by Flow Cytometry von Bay, Lilli T E, Stokke, Trond, Syljuåsen, Randi G, Landsverk, Helga B

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Caspase activation counteracts interferon signaling after G2 checkpoint abrogation by ATR inhibition in irradiated human cancer cells von Eek Mariampillai, Adrian, Hauge, Sissel, Øynebråten, Inger, Rødland, Gro Elise, Corthay, Alexandre, Syljuåsen, Randi G.

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Differential DNA methylation analysis of breast cancer reveals the impact of immune signaling in radiation therapy von Halvorsen, Ann Rita, Helland, Åslaug, Fleischer, Thomas, Haug, Karen Marie, Grenaker Alnæs, Grethe Irene, Nebdal, Daniel, Syljuåsen, Randi G., Touleimat, Nizar, Busato, Florence, Tost, Jörg, Sætersdal, Anna B., Børresen‐Dale, Anne‐Lise, Kristensen, Vessela, Edvardsen, Hege

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Inhibition of Human Chk1 Causes Increased Initiation of DNA Replication, Phosphorylation of ATR Targets, and DNA Breakage von Syljuåsen, Randi G., Sørensen, Claus Storgaard, Hansen, Lasse Tengbjerg, Fugger, Kasper, Lundin, Cecilia, Johansson, Fredrik, Helleday, Thomas, Sehested, Maxwell, Lukas, Jiri, Bartek, Jiri

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Regulators of cyclin-dependent kinases are crucial for maintaining genome integrity in S phase von Beck, Halfdan, Nähse, Viola, Larsen, Marie Sofie Yoo, Groth, Petra, Clancy, Trevor, Lees, Michael, Jørgensen, Mette, Helleday, Thomas, Syljuåsen, Randi G, Sørensen, Claus Storgaard

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The ATM–Chk2–Cdc25A checkpoint pathway guards against radioresistant DNA synthesis von Falck, Jacob, Mailand, Niels, Syljuåsen, Randi G., Bartek, Jiri, Lukas, Jiri

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PLK1-inhibition can cause radiosensitization or radioresistance dependent on the treatment schedule von Lund-Andersen, Christin, Patzke, Sebastian, Nähse-Kumpf, Viola, Syljuåsen, Randi G

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