Poly (ADP-ribose) polymerase inhibitors: recent advances and future development von Scott, Clare L, Swisher, Elizabeth M, Kaufmann, Scott H

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Rucaparib in relapsed, platinum-sensitive high-grade ovarian carcinoma (ARIEL2 Part 1): an international, multicentre, open-label, phase 2 trial von Swisher, Elizabeth M, Dr Prof, Lin, Kevin K, PhD, Oza, Amit M, Prof, Scott, Clare L, PhD, Giordano, Heidi, MA, Sun, James, PhD, Konecny, Gottfried E, MD, Coleman, Robert L, Prof, Tinker, Anna V, MD, O'Malley, David M, MD, Kristeleit, Rebecca S, MD, Ma, Ling, MD, Bell-McGuinn, Katherine M, MD, Brenton, James D, Prof, Cragun, Janiel M, MD, Oaknin, Ana, MD, Ray-Coquard, Isabelle, Prof, Harrell, Maria I, PhD, Mann, Elaina, MS, Kaufmann, Scott H, Prof, Floquet, Anne, MD, Leary, Alexandra, MD, Harding, Thomas C, PhD, Goble, Sandra, MS, Maloney, Lara, BA, Isaacson, Jeff, PhD, Allen, Andrew R, MD, Rolfe, Lindsey, MBChB, Yelensky, Roman, PhD, Raponi, Mitch, PhD, McNeish, Iain A, Prof

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Final Overall Survival of a Randomized Trial of Bevacizumab for Primary Treatment of Ovarian Cancer von Tewari, Krishnansu S, Burger, Robert A, Enserro, Danielle, Norquist, Barbara M, Swisher, Elizabeth M, Brady, Mark F, Bookman, Michael A, Fleming, Gini F, Huang, Helen, Homesley, Howard D, Fowler, Jeffrey M, Greer, Benjamin E, Boente, Matthew, Liang, Sharon X, Ye, Chenglin, Bais, Carlos, Randall, Leslie M, Chan, John K, Ferriss, J Stuart, Coleman, Robert L, Aghajanian, Carol, Herzog, Thomas J, DiSaia, Philip J, Copeland, Larry J, Mannel, Robert S, Birrer, Michael J, Monk, Bradley J

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Combination of PARP Inhibitor Olaparib, and PD-L1 Inhibitor Durvalumab, in Recurrent Ovarian Cancer: a Proof-of-Concept Phase II Study von Lampert, Erika J, Zimmer, Alexandra, Padget, Michelle, Cimino-Mathews, Ashley, Nair, Jayakumar R, Liu, Yingmiao, Swisher, Elizabeth M, Hodge, James W, Nixon, Andrew B, Nichols, Erin, Bagheri, Mohammad H, Levy, Elliott, Radke, Marc R, Lipkowitz, Stanley, Annunziata, Christina M, Taube, Janis M, Steinberg, Seth M, Lee, Jung-Min

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Biomarkers of Response and Resistance to DNA Repair Targeted Therapies von Stover, Elizabeth H, Konstantinopoulos, Panagiotis A, Matulonis, Ursula A, Swisher, Elizabeth M

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Secondary mutations of BRCA1/2 and drug resistance von Dhillon, Kiranjit K., Swisher, Elizabeth M., Taniguchi, Toshiyasu

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Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer von Färkkilä, Anniina, Gulhan, Doga C., Casado, Julia, Jacobson, Connor A., Nguyen, Huy, Kochupurakkal, Bose, Maliga, Zoltan, Yapp, Clarence, Chen, Yu-An, Schapiro, Denis, Zhou, Yinghui, Graham, Julie R., Dezube, Bruce J., Munster, Pamela, Santagata, Sandro, Garcia, Elizabeth, Rodig, Scott, Lako, Ana, Chowdhury, Dipanjan, Shapiro, Geoffrey I., Matulonis, Ursula A., Park, Peter J., Hautaniemi, Sampsa, Sorger, Peter K., Swisher, Elizabeth M., D’Andrea, Alan D., Konstantinopoulos, Panagiotis A.

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Genome-wide and high-density CRISPR-Cas9 screens identify point mutations in PARP1 causing PARP inhibitor resistance von Pettitt, Stephen J., Krastev, Dragomir B., Brandsma, Inger, Dréan, Amy, Song, Feifei, Aleksandrov, Radoslav, Harrell, Maria I., Menon, Malini, Brough, Rachel, Campbell, James, Frankum, Jessica, Ranes, Michael, Pemberton, Helen N., Rafiq, Rumana, Fenwick, Kerry, Swain, Amanda, Guettler, Sebastian, Lee, Jung-Min, Swisher, Elizabeth M., Stoynov, Stoyno, Yusa, Kosuke, Ashworth, Alan, Lord, Christopher J.

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Germline and Somatic Mutations in Homologous Recombination Genes Predict Platinum Response and Survival in Ovarian, Fallopian Tube, and Peritoneal Carcinomas von PENNINGTON, Kathryn P, WALSH, Tom, AGNEW, Kathy J, PRITCHARD, Colin C, SCROGGINS, Sheena, GARCIA, Rochelle L, KING, Mary-Claire, SWISHER, Elizabeth M, HARRELL, Maria I, LEE, Ming K, PENNIL, Christopher C, RENDI, Mara H, THORNTON, Anne, NORQUIST, Barbara M, CASADEI, Silvia, NORD, Alexander S

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Mutations in 12 genes for inherited ovarian, fallopian tube, and peritoneal carcinoma identified by massively parallel sequencing von Walsh, Tom, Casadei, Silvia, Lee, Ming K, Pennil, Christopher C, Nord, Alex S, Thornton, Anne M, Roeb, Wendy, Agnew, Kathy J, Stray, Sunday M, Wickramanayake, Anneka, Norquist, Barbara, Pennington, Kathryn P, Garcia, Rochelle L, King, Mary-Claire, Swisher, Elizabeth M

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BRCA Reversion Mutations in Circulating Tumor DNA Predict Primary and Acquired Resistance to the PARP Inhibitor Rucaparib in High-Grade Ovarian Carcinoma von Lin, Kevin K, Harrell, Maria I, Oza, Amit M, Oaknin, Ana, Ray-Coquard, Isabelle, Tinker, Anna V, Helman, Elena, Radke, Marc R, Say, Carmen, Vo, Lan-Thanh, Mann, Elaina, Isaacson, Jeffrey D, Maloney, Lara, O'Malley, David M, Chambers, Setsuko K, Kaufmann, Scott H, Scott, Clare L, Konecny, Gottfried E, Coleman, Robert L, Sun, James X, Giordano, Heidi, Brenton, James D, Harding, Thomas C, McNeish, Iain A, Swisher, Elizabeth M

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Secondary Somatic Mutations Restoring BRCA1/2 Predict Chemotherapy Resistance in Hereditary Ovarian Carcinomas von NORQUIST, Barbara, WURZ, Kaitlyn A, PENNIL, Christopher C, GARCIA, Rochelle, GROSS, Jenny, SAKAI, Wataru, KARLAN, Beth Y, TANIGUCHI, Toshiyasu, SWISHER, Elizabeth M

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Prexasertib, a cell cycle checkpoint kinase 1 and 2 inhibitor, in BRCA wild-type recurrent high-grade serous ovarian cancer: a first-in-class proof-of-concept phase 2 study von Lee, Jung-Min, Nair, Jayakumar, Zimmer, Alexandra, Lipkowitz, Stanley, Annunziata, Christina M, Merino, Maria J, Swisher, Elizabeth M, Harrell, Maria I, Trepel, Jane B, Lee, Min-Jung, Bagheri, Mohammad H, Botesteanu, Dana-Adriana, Steinberg, Seth M, Minasian, Lori, Ekwede, Irene, Kohn, Elise C

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Mutations in Homologous Recombination Genes and Outcomes in Ovarian Carcinoma Patients in GOG 218: An NRG Oncology/Gynecologic Oncology Group Study von Norquist, Barbara M, Brady, Mark F, Harrell, Maria I, Walsh, Tom, Lee, Ming K, Gulsuner, Suleyman, Bernards, Sarah S, Casadei, Silvia, Burger, Robert A, Tewari, Krishnansu S, Backes, Floor, Mannel, Robert S, Glaser, Gretchen, Bailey, Cheryl, Rubin, Stephen, Soper, John, Lankes, Heather A, Ramirez, Nilsa C, King, Mary Claire, Birrer, Michael J, Swisher, Elizabeth M

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Prediction of DNA Repair Inhibitor Response in Short-Term Patient-Derived Ovarian Cancer Organoids von Hill, Sarah J, Decker, Brennan, Roberts, Emma A, Horowitz, Neil S, Muto, Michael G, Worley, Jr, Michael J, Feltmate, Colleen M, Nucci, Marisa R, Swisher, Elizabeth M, Nguyen, Huy, Yang, Chunyu, Morizane, Ryuji, Kochupurakkal, Bose S, Do, Khanh T, Konstantinopoulos, Panagiotis A, Liu, Joyce F, Bonventre, Joseph V, Matulonis, Ursula A, Shapiro, Geoffrey I, Berkowitz, Ross S, Crum, Christopher P, D'Andrea, Alan D

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Detection of inherited mutations for breast and ovarian cancer using genomic capture and massively parallel sequencing von Walsh, Tom, Lee, Ming K., Casadei, Silvia, Thornton, Anne M., Stray, Sunday M., Pennil, Christopher, Nord, Alex S., Mandell, Jessica B., Swisher, Elizabeth M., King, Mary-Claire

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An atomistic model for the thermal resistance of a liquid–solid interface von Hadjiconstantinou, N.G., Swisher, M.M.

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A phase II evaluation of the potent, highly selective PARP inhibitor veliparib in the treatment of persistent or recurrent epithelial ovarian, fallopian tube, or primary peritoneal... von Coleman, Robert L, Sill, Michael W, Bell-McGuinn, Katherine, Aghajanian, Carol, Gray, Heidi J, Tewari, Krishnansu S, Rubin, Steven C, Rutherford, Thomas J, Chan, John K, Chen, Alice, Swisher, Elizabeth M

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Acquired RAD51C Promoter Methylation Loss Causes PARP Inhibitor Resistance in High-Grade Serous Ovarian Carcinoma von Nesic, Ksenija, Kondrashova, Olga, Hurley, Rachel M, McGehee, Cordelia D, Vandenberg, Cassandra J, Ho, Gwo-Yaw, Lieschke, Elizabeth, Dall, Genevieve, Bound, Nirashaa, Shield-Artin, Kristy, Radke, Marc, Musafer, Ashan, Chai, Zi Qing, Ghamsari, Mohammad Reza Eftekhariyan, Harrell, Maria I, Kee, Damien, Olesen, Inger, McNally, Orla, Traficante, Nadia, Australian Ovarian Cancer Study, DeFazio, Anna, Bowtell, David D L, Swisher, Elizabeth M, Weroha, S John, Nones, Katia, Waddell, Nicola, Kaufmann, Scott H, Dobrovic, Alexander, Wakefield, Matthew J, Scott, Clare L

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Secondary mutations as a mechanism of cisplatin resistance in BRCA2 -mutated cancers von Taniguchi, Toshiyasu, Sakai, Wataru, Swisher, Elizabeth M, Karlan, Beth Y, Agarwal, Mukesh K, Higgins, Jake, Friedman, Cynthia, Villegas, Emily, Jacquemont, Céline, Farrugia, Daniel J, Couch, Fergus J, Urban, Nicole

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