Protein Methyltransferases: A Distinct, Diverse, and Dynamic Family of Enzymes von Boriack-Sjodin, P. Ann, Swinger, Kerren K

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IHF and HU: flexible architects of bent DNA von Swinger, Kerren K, Rice, Phoebe A

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PARP7 negatively regulates the type I interferon response in cancer cells and its inhibition triggers antitumor immunity von Gozgit, Joseph M., Vasbinder, Melissa M., Abo, Ryan P., Kunii, Kaiko, Kuplast-Barr, Kristy G., Gui, Bin, Lu, Alvin Z., Molina, Jennifer R., Minissale, Elena, Swinger, Kerren K., Wigle, Tim J., Blackwell, Danielle J., Majer, Christina R., Ren, Yue, Niepel, Mario, Varsamis, Zacharenia A., Nayak, Sunaina P., Bamberg, Ellen, Mo, Jan-Rung, Church, W. David, Mady, Ahmed S.A., Song, Jeff, Utley, Luke, Rao, Patricia E., Mitchison, Timothy J., Kuntz, Kevin W., Richon, Victoria M., Keilhack, Heike

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Structure-based Analysis of HU–DNA Binding von Swinger, Kerren K., Rice, Phoebe A.

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Characterization of novel small-molecule NRF2 activators: Structural and biochemical validation of stereospecific KEAP1 binding von Huerta, Carlos, Jiang, Xin, Trevino, Isaac, Bender, Christopher F., Ferguson, Deborah A., Probst, Brandon, Swinger, Kerren K., Stoll, Vincent S., Thomas, Philip J., Dulubova, Irina, Visnick, Melean, Wigley, W. Christian

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Crystal structure of the RNA component of bacterial ribonuclease P von Swinger, Kerren K, Torres-Larios, Alfredo, Krasilnikov, Andrey S, Pan, Tao, Mondragón, Alfonso

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Identification of a peptide inhibitor for the histone methyltransferase WHSC1 von Morrison, Michael J, Boriack-Sjodin, P Ann, Swinger, Kerren K, Wigle, Tim J, Sadalge, Dipti, Kuntz, Kevin W, Scott, Margaret Porter, Janzen, William P, Chesworth, Richard, Duncan, Kenneth W, Harvey, Darren M, Lampe, John W, Mitchell, Lorna H, Copeland, Robert A

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Flexible DNA bending in HU–DNA cocrystal structures von Swinger, Kerren K., Lemberg, Kathryn M., Zhang, Ying, Rice, Phoebe A.

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Flexible DNA bending in HU-DNA cocrystal structures von Swinger, Kerren K., Lemberg, Kathryn M., Zhang, Ying, Rice, Phoebe A.

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Structure of ribonuclease P — a universal ribozyme von Torres-Larios, Alfredo, Swinger, Kerren K, Pan, Tao, Mondragón, Alfonso

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Structure of a bacterial ribonuclease P holoenzyme in complex with tRNA von Reiter, Nicholas J, Osterman, Amy, Swinger, Kerren K, Mondragón, Alfonso, Pan, Tao, Torres-Larios, Alfredo

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A potent and selective PARP14 inhibitor decreases protumor macrophage gene expression and elicits inflammatory responses in tumor explants von Schenkel, Laurie B., Molina, Jennifer R., Swinger, Kerren K., Abo, Ryan, Blackwell, Danielle J., Lu, Alvin Z., Cheung, Anne E., Church, W. David, Kunii, Kaiko, Kuplast-Barr, Kristy G., Majer, Christina R., Minissale, Elena, Mo, Jan-Rung, Niepel, Mario, Reik, Christopher, Ren, Yue, Vasbinder, Melissa M., Wigle, Tim J., Richon, Victoria M., Keilhack, Heike, Kuntz, Kevin W.

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Azaindole-Based Inhibitors of Cdc7 Kinase: Impact of the Pre-DFG Residue, Val 195 von Tong, Yunsong, Stewart, Kent D, Florjancic, Alan S, Harlan, John E, Merta, Philip J, Przytulinska, Magdalena, Soni, Nirupama, Swinger, Kerren K, Zhu, Haizhong, Johnson, Eric F, Shoemaker, Alexander R, Penning, Thomas D

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In Vitro and Cellular Probes to Study PARP Enzyme Target Engagement von Wigle, Tim J., Blackwell, Danielle J., Schenkel, Laurie B., Ren, Yue, Church, W. David, Desai, Hetvi J., Swinger, Kerren K., Santospago, Andrew G., Majer, Christina R., Lu, Alvin Z., Niepel, Mario, Perl, Nicholas R., Vasbinder, Melissa M., Keilhack, Heike, Kuntz, Kevin W.

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Aryl Pyrazoles as Potent Inhibitors of Arginine Methyltransferases: Identification of the First PRMT6 Tool Compound von Mitchell, Lorna H., Drew, Allison E., Ribich, Scott A., Rioux, Nathalie, Swinger, Kerren K., Jacques, Suzanne L., Lingaraj, Trupti, Boriack-Sjodin, P. Ann, Waters, Nigel J., Wigle, Tim J., Moradei, Oscar, Jin, Lei, Riera, Tom, Porter-Scott, Margaret, Moyer, Mikel P., Smith, Jesse J., Chesworth, Richard, Copeland, Robert A.

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Targeted Degradation of PARP14 Using a Heterobifunctional Small Molecule von Wigle, Tim J., Ren, Yue, Molina, Jennifer R., Blackwell, Danielle J., Schenkel, Laurie B., Swinger, Kerren K., Kuplast‐Barr, Kristy, Majer, Christina R., Church, W. David, Lu, Alvin Z., Mo, Jason, Abo, Ryan, Cheung, Anne, Dorsey, Bryan W., Niepel, Mario, Perl, Nicholas R., Vasbinder, Melissa M., Keilhack, Heike, Kuntz, Kevin W.

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A High-Throughput Mass Spectrometry Assay Coupled with Redox Activity Testing Reduces Artifacts and False Positives in Lysine Demethylase Screening von Wigle, Tim J., Swinger, Kerren K., Campbell, John E., Scholle, Michael D., Sherrill, John, Admirand, Elizabeth A., Boriack-Sjodin, P. Ann, Kuntz, Kevin W., Chesworth, Richard, Moyer, Mikel P., Scott, Margaret Porter, Copeland, Robert A.

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Forced Self-Modification Assays as a Strategy to Screen MonoPARP Enzymes von Wigle, Tim J., Church, W. David, Majer, Christina R., Swinger, Kerren K., Aybar, Demet, Schenkel, Laurie B., Vasbinder, Melissa M., Brendes, Arne, Beck, Claudia, Prahm, Martin, Wegener, Dennis, Chang, Paul, Kuntz, Kevin W.

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Selective Pharmaceutical Inhibition of PARP14 Mitigates Allergen-Induced IgE and Mucus Overproduction in a Mouse Model of Pulmonary Allergic Response von Eddie, Alex M, Chen, Kevin W, Schenkel, Laurie B, Swinger, Kerren K, Molina, Jennifer R, Kunii, Kaiko, Raybuck, Ariel L, Keilhack, Heike, Gibson-Corley, Katherine N, Niepel, Mario, Peebles, R Stokes, Boothby, Mark R, Cho, Sung Hoon

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Imidazo[2,1- b]thiazoles: Multitargeted inhibitors of both the insulin-like growth factor receptor and members of the epidermal growth factor family of receptor tyrosine kinases von Fidanze, Steve D., Erickson, Scott A., Wang, Gary T., Mantei, Robert, Clark, Richard F., Sorensen, Bryan K., Bamaung, Nwe Y., Kovar, Peter, Johnson, Eric F., Swinger, Kerren K., Stewart, Kent D., Zhang, Qian, Tucker, Lora A., Pappano, William N., Wilsbacher, Julie L., Wang, Jieyi, Sheppard, George S., Bell, Randy L., Davidsen, Steven K., Hubbard, Robert D.

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