Inhibiting Mitochondria Function By Bcl-2 Inhibitor Venetoclax and Complex I Inhibitor Iacs-010759 Eliminate Leukemia Cells in Pre-Clinical AML Models von Zhang, Qi, Lodi, Alessia, Sweeney, Shannon Renee, Han, Lina, Cai, Tianyu, Kuruvilla, Vinitha Mary, Cavazos, Antonio, Ma, Helen, Tabe, Yoko, Marszalek, Joseph R, Tiziani, Stefano, Konopleva, Marina Y

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Choline uptake and metabolism modulate macrophage immunity von Sanchez-Lopez, Elsa, Zhong, Zhenyu, Stubelius, Alexandra, Sweeney, Shannon Renee, Booshehri, Laela, Antonucci, Laura, Liu-Bryan, Ru, Lodi, Alessia, Terkeltaub, Robert, Lacal, Juan Carlos, Murphy, Anne N., Hoffman, Hal M, Tiziani, Stefano, Guma, Monica, Karin, Michael

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Glutaminase Inhibition Overcomes Acquired Resistance to Mitochondrial Complex I in NOTCH1-Driven T-Cell Acute Lymphoblastic Leukemias (T-ALL) Via Block of Glutamine Driven Reductiv... von Baran, Natalia, Lodi, Alessia, Sweeney, Shannon Renee, Kuruvilla, Vinitha Mary, Cavazos, Antonio, Herranz, Daniel, Skwarska, Anna, Warmoes, Marc, Davis, Eric, Harutyunyan, Karine, Feng, Ningping, Gay, Jason P, Kaminski, Marcin, Konoplev, Sergej, Jabbour, Elias, Ferrando, Adolfo A., Di Francesco, Maria E, Lorenzi, Philip, Marszalek, Joseph R, Tiziani, Stefano, Konopleva, Marina Y, Renu, Pandey

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Overcoming NOTCH1-Driven Chemoresistance in T-Cell Acute Lymphoblastic Leukemia Via Metabolic Intervention with Oxphos Inhibitor von Baran, Natalia, Lodi, Alessia, Dhungana, Yogesh, Sweeney, Shannon RENEE, Renu, Pandey, Herbrich, Shelley, Hoff, Fieke W, Skwarska, Anna, Kaplan, Mecit, Kuruvilla, Vinitha Mary, Cavazos, Antonio, Warmoes, Marc, Rojas-Sutterlin, Shanti, Haman, Andre, Veiga, Diogo Troggian, Furudate, Ken, Ma, Helen, Harutyunyan, Karine, Yang, Wentao, Gagea, Mihai, Du, Di, Daher, May, Garcia, Luciana Melo, Piya, Sujan, Ruvolo, Vivian, Shanmugavelandy, Sriram, Feng, Ningping, Gay, Jason P, Havranek, Ondrej, Henderson, Jared, Tomczak, Katarzyna, Kaminski, Marcin, Herranz, Daniel, Ferrando, Adolfo, Jabbour, Elias, Di Francesco, Maria E, Teachey, David T., Horton, Terzah M., Rezvani, Katayoun, Yang, Jun J., Kornblau, Steven M., Davis, Eric, Takahashi, Koichi, Andreeff, Michael, Marszalek, Joseph R, Lorenzi, Philip, Yu, Jiyang, Tiziani, Stefano, Hoang, Trang, Konopleva, Marina

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Mitochondrial Complex I Inhibitor Iacs-010759 Reverses the NOTCH1-Driven Metabolic Reprogramming in T-ALL Via Blockade of Oxidative Phosphorylation: Synergy with Chemotherapy and G... von Baran, Natalia, Lodi, Alessia, Sweeney, Shannon Renee, Renu, Pandey, Kuruvilla, Vinitha Mary, Cavazos, Antonio, Herranz, Daniel, Skwarska, Anna, Warmoes, Marc, Davis, R. Eric, Harutyunyan, Karine, Feng, Ningping, Gay, Jason P, Konoplev, Sergej Naumovich, Kaminski, Marcin, Kovacs, Jeffrey J, Du, Di, Jabbour, Elias J., Ferrando, Adolfo A., Di Francesco, Maria E, Lorenzi, Philip L, Marszalek, Joseph R, Tiziani, Stefano, Konopleva, Marina Y.

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Inhibition of Oxphos with Iacs-010759 Depletes AML Leukemia Initiating Cells (LIC) in Vitro and Improves Survival in Pre-Clinical AML Models von Baran, Natalia, Han, Lina, Sweeney, Shannon Renee, Lodi, Alessia, Herbrich, Shelley, Cavazos, Antonio, Ma, Helen, Gay, Jason P, Feng, Ningping, Chen, Hsiang-Chun, Kaminski, Marcin, Dunner, Kenneth, Tang, Guilin, Alatrash, Gheath, Molina, Jennifer, Guzman, Monica L., Ning, Jing, Tiziani, Stefano, Marszalek, Joseph R, Konopleva, Marina

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Novel Complex I inhibitor IACS-010759 Targets Leukemia Initiating Cells (LICs) in AML Patients von Baran, Natalia, Han, Lina, Herbrich, Shelley, Sweeney, Shannon Renee, Lodi, Alessia, Gay, Jason, Feng, Ningping, Molina, Jennifer R., Kaminski, Marcin, Guzman, Monica L., Al-Atrash, Gheath, Tiziani, Stefano, Marszalek, Joseph R., Konopleva, Marina

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Inhibiting glutaminase in acute myeloid leukemia: metabolic dependency of selected AML subtypes von Matre, Polina, Velez, Juliana, Jacamo, Rodrigo, Qi, Yuan, Su, Xiaoping, Cai, Tianyu, Chan, Steven M, Lodi, Alessia, Sweeney, Shannon R, Ma, Helen, Davis, Richard Eric, Baran, Natalia, Haferlach, Torsten, Su, Xiaohua, Flores, Elsa Renee, Gonzalez, Doriann, Konoplev, Sergej, Samudio, Ismael, DiNardo, Courtney, Majeti, Ravi, Schimmer, Aaron D, Li, Weiqun, Wang, Taotao, Tiziani, Stefano, Konopleva, Marina

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