Efficacy and Safety of Controlled-Release Versus Immediate-Release Oxycodone: Randomized, Double-Blind Evaluation in Patients with Chronic Back Pain von Hale, Martin E, Fleischmann, Roy, Salzman, Robert, Wild, James, Iwan, Tad, Swanton, Ruth E, Kaiko, Robert F, Lacouture, Peter G

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A pharmacokinetic/pharmacodynamic study of controlled-release oxycodone von Benzinger, David P., Miotto, Jahanara, Grandy, Robert P., Thomas, Gordon B., Swanson, Ruth E., Fitzmartin, Ronald D.

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Comparative Efficacy of Oral Extended-Release Hydromorphone and Immediate-Release Hydromorphone in Patients with Persistent Moderate to Severe Pain: Two Randomized Controlled Trial... von Grosset, Alan B., Roberts, Michael S., Woodson, Mark E., Shi, Minggao, Swanton, Ruth E., Reder, Robert F., Buckley, Barbara J.

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Relative variability in bioavailability of oral controlled-release formulations of oxycodone and morphine von Colucci, R D, Swanton, R E, Thomas, G B, Kaiko, R F

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Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set von Klein, E.A., Richards, D., Cohn, A., Tummala, M., Lapham, R., Cosgrove, D., Chung, G., Clement, J., Gao, J., Hunkapiller, N., Jamshidi, A., Kurtzman, K.N., Seiden, M.V., Swanton, C., Liu, M.C.

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Collateral damage: the impact on outcomes from cancer surgery of the COVID-19 pandemic von Sud, A., Jones, M.E., Broggio, J., Loveday, C., Torr, B., Garrett, A., Nicol, D.L., Jhanji, S., Boyce, S.A., Gronthoud, F., Ward, P., Handy, J.M., Yousaf, N., Larkin, J., Suh, Y-E., Scott, S., Pharoah, P.D.P., Swanton, C., Abbosh, C., Williams, M., Lyratzopoulos, G., Houlston, R., Turnbull, C.

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Predicting response to cancer immunotherapy using noninvasive radiomic biomarkers von Trebeschi, S., Drago, S.G., Birkbak, N.J., Kurilova, I., Cǎlin, A.M., Delli Pizzi, A., Lalezari, F., Lambregts, D.M.J., Rohaan, M.W., Parmar, C., Rozeman, E.A., Hartemink, K.J., Swanton, C., Haanen, J B A G, Blank, C.U., Smit, E.F., Beets-Tan, R.G.H., Aerts, H.J.W.L

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A framework to rank genomic alterations as targets for cancer precision medicine: the ESMO Scale for Clinical Actionability of molecular Targets (ESCAT) von Mateo, J., Chakravarty, D., Dienstmann, R., Jezdic, S., Gonzalez-Perez, A., Lopez-Bigas, N., Ng, C.K.Y., Bedard, P.L., Tortora, G., Douillard, J.-Y., Van Allen, E.M., Schultz, N., Swanton, C., André, F., Pusztai, L.

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Differential binding affinity of mutated peptides for MHC class I is a predictor of survival in advanced lung cancer and melanoma von Ghorani, E., Rosenthal, R., McGranahan, N., Reading, J.L., Lynch, M., Peggs, K.S., Swanton, C., Quezada, S.A.

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Replication stress links structural and numerical cancer chromosomal instability von Burrell, Rebecca A., McClelland, Sarah E., Endesfelder, David, Groth, Petra, Weller, Marie-Christine, Shaikh, Nadeem, Domingo, Enric, Kanu, Nnennaya, Dewhurst, Sally M., Gronroos, Eva, Chew, Su Kit, Rowan, Andrew J., Schenk, Arne, Sheffer, Michal, Howell, Michael, Kschischo, Maik, Behrens, Axel, Helleday, Thomas, Bartek, Jiri, Tomlinson, Ian P., Swanton, Charles

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Preexisting and de novo humoral immunity to SARS-CoV-2 in humans von Ng, Kevin W., Faulkner, Nikhil, Cornish, Georgina H., Rosa, Annachiara, Harvey, Ruth, Hussain, Saira, Ufferts, Rachel, Earl, Christopher, Wrobel, Antoni G., Benton, Donald J., Roustan, Chloe, Bolland, William, Thompson, Rachael, Agua-Doce, Ana, Hobson, Philip, Heaney, Judith, Rickman, Hannah, Paraskevopoulou, Stavroula, Houlihan, Catherine F., Thomson, Kirsty, Sanchez, Emilie, Shin, Gee Yen, Spyer, Moira J., Joshi, Dhira, O'Reilly, Nicola, Walker, Philip A., Kjaer, Svend, Riddell, Andrew, Moore, Catherine, Jebson, Bethany R., Wilkinson, Meredyth, Marshall, Lucy R., Rosser, Elizabeth C., Radziszewska, Anna, Peckham, Hannah, Ciurtin, Coziana, Wedderburn, Lucy R., Beale, Rupert, Swanton, Charles, Gandhi, Sonia, Stockinger, Brigitta, McCauley, John, Gambill, Steve J., McCoy, Laura E., Cherepanov, Peter, Nastouli, Eleni, Kassiotis, George

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Additive design: the concept and data analysis von Oliveira, M C, Pereira, G A M, Ferreira, E A, Santos, J B, Knezevic, S Z, Werle, R, Swanton, Clarence

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Extreme chromosomal instability forecasts improved outcome in ER-negative breast cancer: a prospective validation cohort study from the TACT trial von Jamal-Hanjani, M., A'Hern, R., Birkbak, N.J., Gorman, P., Grönroos, E., Ngang, S., Nicola, P., Rahman, L., Thanopoulou, E., Kelly, G., Ellis, P., Barrett-Lee, P., Johnston, S.R.D., Bliss, J., Roylance, R., Swanton, C.

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SETD2 loss-of-function promotes renal cancer branched evolution through replication stress and impaired DNA repair von Kanu, N, Grönroos, E, Martinez, P, Burrell, R A, Yi Goh, X, Bartkova, J, Maya-Mendoza, A, Mistrík, M, Rowan, A J, Patel, H, Rabinowitz, A, East, P, Wilson, G, Santos, C R, McGranahan, N, Gulati, S, Gerlinger, M, Birkbak, N J, Joshi, T, Alexandrov, L B, Stratton, M R, Powles, T, Matthews, N, Bates, P A, Stewart, A, Szallasi, Z, Larkin, J, Bartek, J, Swanton, C

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Sensitive and specific multi-cancer detection and localization using methylation signatures in cell-free DNA von Liu, M.C., Klein, E.A., Swanton, C., Seiden, M.V., Klein, Eric A., Yeatman, Timothy J., Cohn, Allen L., Lapham, Rosanna, Parker, Alexander S., McIntyre, Kristi, Sekeres, Mikkael A., Siegel, Robert, Wang, Xuezhong, Cosgrove, David P., Trent, Jonathan, Thiel, David D., Garbo, Lawrence E., Giguere, Jeffrey K., Michels, Ross M., Harris, Ronald P., Richey, Stephen L., McCarthy, Timothy A., Couch, Fergus J., Wilks, Sharon T., Krie, Amy K., Balaraman, Rama, Rieger-Christ, Kimberly, Sullivan, Travis, Greenwald, Daniel R., Oh, William, Tsao, Che-Kai, Kennecke, Hagen F., Manhas, Atisha P., Ulrich, Brian K., Kovoor, Philip A., Stokoe, Christopher, Courtright, Jay G., Larson, Timothy G., Seiden, Michael V., Cummings, Steven R., Absalan, Farnaz, Alexander, Gregory, Allen, Brian, Aravanis, Alexander M., Beausang, John F., Berman, Jennifer, Bredno, Joerg, Calef, Robert, Cann, Gordon, Carter, Jeremy, Chen, Xiaoji, Chien, Tom C., Davydov, Konstantin, Demas, Vasiliki, Fields, Alexander P., Freese, Peter, Gnerre, Sante, Gross, Samuel, Hall, Megan P., Hartman, Anne-Renee, Hou, Chenlu, Hubbell, Earl, Jiang, Roger, Kim, TaeHyung, Klausner, Richard D., Kurtzman, Kathryn N., Lee, Mark, Lin, Wendy, Lipson, Jafi, Maddala, Tara, Maher, M. Cyrus, Melton, Collin, Mich, Andrea, Newman, Joshua, Nicula, Virgil, Nikolic, Ongjen, Patel, Shilpen, Rava, Richard, Schellenberger, Jan, Scott, Eric, Sehnert, Amy J., Shaknovich, Rita, Shanmugam, Avinash, Shashidhar, K.C., Shenoy, Archana, Shojaee, Seyedmehdi, Tang, Susan, Valouev, Anton, Venn, Oliver, Williams, Richard T., Wu, Tony, Yakym, Christopher, Yang, Xiao, Yecies, Jessica, Yip, Alexander S., Yue, Jeanne, Zhang, Lily, Zhang, Lori (Quan), Curtis, Christina, Berry, Donald A.

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Evolution and clinical impact of co-occurring genetic alterations in advanced-stage EGFR-mutant lung cancers von Blakely, Collin M, Watkins, Thomas B K, Wu, Wei, Gini, Beatrice, Chabon, Jacob J, McCoach, Caroline E, McGranahan, Nicholas, Wilson, Gareth A, Birkbak, Nicolai J, Olivas, Victor R, Rotow, Julia, Maynard, Ashley, Wang, Victoria, Gubens, Matthew A, Banks, Kimberly C, Lanman, Richard B, Caulin, Aleah F, St John, John, Cordero, Anibal R, Giannikopoulos, Petros, Simmons, Andrew D, Mack, Philip C, Gandara, David R, Husain, Hatim, Doebele, Robert C, Riess, Jonathan W, Diehn, Maximilian, Swanton, Charles, Bivona, Trever G

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Intratumoural evolutionary landscape of high-risk prostate cancer: the PROGENY study of genomic and immune parameters von Linch, M., Goh, G., Hiley, C., Shanmugabavan, Y., McGranahan, N., Rowan, A., Wong, Y.N.S., King, H., Furness, A., Freeman, A., Linares, J., Akarca, A., Herrero, J., Rosenthal, R., Harder, N., Schmidt, G., Wilson, G.A., Birkbak, N.J., Mitter, R., Dentro, S., Cathcart, P., Arya, M., Johnston, E., Scott, R., Hung, M., Emberton, M., Attard, G., Szallasi, Z., Punwani, S., Quezada, S.A., Marafioti, T., Gerlinger, M., Ahmed, H.U., Swanton, C.

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Cycling of extracellular DNA in the soil environment von Levy-Booth, David J., Campbell, Rachel G., Gulden, Robert H., Hart, Miranda M., Powell, Jeff R., Klironomos, John N., Pauls, K. Peter, Swanton, Clarence J., Trevors, Jack T., Dunfield, Kari E.

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Classifying the evolutionary and ecological features of neoplasms von Maley, Carlo C., Aktipis, Athena, Graham, Trevor A., Sottoriva, Andrea, Boddy, Amy M., Janiszewska, Michalina, Silva, Ariosto S., Gerlinger, Marco, Yuan, Yinyin, Pienta, Kenneth J., Anderson, Karen S., Gatenby, Robert, Swanton, Charles, Posada, David, Wu, Chung-I, Schiffman, Joshua D., Hwang, E. Shelley, Polyak, Kornelia, Anderson, Alexander R. A., Brown, Joel S., Greaves, Mel, Shibata, Darryl

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Tracking the Evolution of Non–Small-Cell Lung Cancer von Jamal-Hanjani, Mariam, Wilson, Gareth A, McGranahan, Nicholas, Birkbak, Nicolai J, Watkins, Thomas B.K, Veeriah, Selvaraju, Shafi, Seema, Johnson, Diana H, Mitter, Richard, Rosenthal, Rachel, Salm, Max, Horswell, Stuart, Escudero, Mickael, Matthews, Nik, Rowan, Andrew, Chambers, Tim, Moore, David A, Turajlic, Samra, Xu, Hang, Lee, Siow-Ming, Forster, Martin D, Ahmad, Tanya, Hiley, Crispin T, Abbosh, Christopher, Falzon, Mary, Borg, Elaine, Marafioti, Teresa, Lawrence, David, Hayward, Martin, Kolvekar, Shyam, Panagiotopoulos, Nikolaos, Janes, Sam M, Thakrar, Ricky, Ahmed, Asia, Blackhall, Fiona, Summers, Yvonne, Shah, Rajesh, Joseph, Leena, Quinn, Anne M, Crosbie, Phil A, Naidu, Babu, Middleton, Gary, Langman, Gerald, Trotter, Simon, Nicolson, Marianne, Remmen, Hardy, Kerr, Keith, Chetty, Mahendran, Gomersall, Lesley, Fennell, Dean A, Nakas, Apostolos, Rathinam, Sridhar, Anand, Girija, Khan, Sajid, Russell, Peter, Ezhil, Veni, Ismail, Babikir, Irvin-Sellers, Melanie, Prakash, Vineet, Lester, Jason F, Kornaszewska, Malgorzata, Attanoos, Richard, Adams, Haydn, Davies, Helen, Dentro, Stefan, Taniere, Philippe, O’Sullivan, Brendan, Lowe, Helen L, Hartley, John A, Iles, Natasha, Bell, Harriet, Ngai, Yenting, Shaw, Jacqui A, Herrero, Javier, Szallasi, Zoltan, Schwarz, Roland F, Stewart, Aengus, Quezada, Sergio A, Le Quesne, John, Van Loo, Peter, Dive, Caroline, Hackshaw, Allan, Swanton, Charles

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