Field relations, age, and tectonic setting of metamorphic and plutonic rocks in the Creignish Hills – North Mountain area, southwestern Cape Breton Island, Nova Scotia, Canada von White, Chris E, Barr, Sandra M, Davis, Donald W, Swanton, David S, Ketchum, John W.F, Reynolds, Peter H

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When too much isn't enough: Does current food production meet global nutritional needs? von Kc, Krishna Bahadur, Dias, Goretty M, Veeramani, Anastasia, Swanton, Clarence J, Fraser, David, Steinke, Dirk, Lee, Elizabeth, Wittman, Hannah, Farber, Jeffrey M, Dunfield, Kari, McCann, Kevin, Anand, Madhur, Campbell, Malcolm, Rooney, Neil, Raine, Nigel E, Acker, Rene Van, Hanner, Robert, Pascoal, Samantha, Sharif, Shayan, Benton, Tim G, Fraser, Evan D G

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Targeted Therapy for Advanced Solid Tumors on the Basis of Molecular Profiles: Results From MyPathway, an Open-Label, Phase IIa Multiple Basket Study von Hainsworth, John D, Meric-Bernstam, Funda, Swanton, Charles, Hurwitz, Herbert, Spigel, David R, Sweeney, Christopher, Burris, Howard, Bose, Ron, Yoo, Bongin, Stein, Alisha, Beattie, Mary, Kurzrock, Razelle

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Sensitive and specific multi-cancer detection and localization using methylation signatures in cell-free DNA von Liu, M.C., Klein, E.A., Swanton, C., Seiden, M.V., Klein, Eric A., Yeatman, Timothy J., Cohn, Allen L., Lapham, Rosanna, Parker, Alexander S., McIntyre, Kristi, Sekeres, Mikkael A., Siegel, Robert, Wang, Xuezhong, Cosgrove, David P., Trent, Jonathan, Thiel, David D., Garbo, Lawrence E., Giguere, Jeffrey K., Michels, Ross M., Harris, Ronald P., Richey, Stephen L., McCarthy, Timothy A., Couch, Fergus J., Wilks, Sharon T., Krie, Amy K., Balaraman, Rama, Rieger-Christ, Kimberly, Sullivan, Travis, Greenwald, Daniel R., Oh, William, Tsao, Che-Kai, Kennecke, Hagen F., Manhas, Atisha P., Ulrich, Brian K., Kovoor, Philip A., Stokoe, Christopher, Courtright, Jay G., Larson, Timothy G., Seiden, Michael V., Cummings, Steven R., Absalan, Farnaz, Alexander, Gregory, Allen, Brian, Aravanis, Alexander M., Beausang, John F., Berman, Jennifer, Bredno, Joerg, Calef, Robert, Cann, Gordon, Carter, Jeremy, Chen, Xiaoji, Chien, Tom C., Davydov, Konstantin, Demas, Vasiliki, Fields, Alexander P., Freese, Peter, Gnerre, Sante, Gross, Samuel, Hall, Megan P., Hartman, Anne-Renee, Hou, Chenlu, Hubbell, Earl, Jiang, Roger, Kim, TaeHyung, Klausner, Richard D., Kurtzman, Kathryn N., Lee, Mark, Lin, Wendy, Lipson, Jafi, Maddala, Tara, Maher, M. Cyrus, Melton, Collin, Mich, Andrea, Newman, Joshua, Nicula, Virgil, Nikolic, Ongjen, Patel, Shilpen, Rava, Richard, Schellenberger, Jan, Scott, Eric, Sehnert, Amy J., Shaknovich, Rita, Shanmugam, Avinash, Shashidhar, K.C., Shenoy, Archana, Shojaee, Seyedmehdi, Tang, Susan, Valouev, Anton, Venn, Oliver, Williams, Richard T., Wu, Tony, Yakym, Christopher, Yang, Xiao, Yecies, Jessica, Yip, Alexander S., Yue, Jeanne, Zhang, Lily, Zhang, Lori (Quan), Curtis, Christina, Berry, Donald A.

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Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes von Dentro, Stefan C., Leshchiner, Ignaty, Haase, Kerstin, Wintersinger, Jeff, Deshwar, Amit G., Yu, Kaixian, Rubanova, Yulia, Macintyre, Geoff, Demeulemeester, Jonas, Vázquez-García, Ignacio, Kleinheinz, Kortine, Livitz, Dimitri G., Malikic, Salem, Donmez, Nilgun, Sengupta, Subhajit, Anur, Pavana, Jolly, Clemency, Rosebrock, Daniel, Schumacher, Steven E., Fittall, Matthew, Drews, Ruben M., Yao, Xiaotong, Lee, Juhee, Schlesner, Matthias, Zhu, Hongtu, Adams, David J., McGranahan, Nicholas, Swanton, Charles, Getz, Gad, Boutros, Paul C., Imielinski, Marcin, Beroukhim, Rameen, Sahinalp, S. Cenk, Ji, Yuan, Peifer, Martin, Martincorena, Inigo, Markowetz, Florian, Mustonen, Ville, Yuan, Ke, Gerstung, Moritz, Spellman, Paul T., Wang, Wenyi, Wedge, David C., Dentro, Stefan C., Leshchiner, Ignaty, Gerstung, Moritz, Jolly, Clemency, Haase, Kerstin, Tarabichi, Maxime, Wintersinger, Jeff, Deshwar, Amit G., Yu, Kaixian, Rubanova, Yulia, Macintyre, Geoff, Demeulemeester, Jonas, Anur, Pavana, Beroukhim, Rameen, Boutros, Paul C., Bowtell, David D., Cao, Shaolong, Cmero, Marek, Cun, Yupeng, Dawson, Kevin J., Donmez, Nilgun, Drews, Ruben M., Eils, Roland, Fan, Yu, Fittall, Matthew, Getz, Gad, Ha, Gavin, Imielinski, Marcin, Ji, Yuan, Kleinheinz, Kortine, Lee, Juhee, Lee-Six, Henry, Livitz, Dimitri G., Malikic, Salem, Markowetz, Florian, Martincorena, Inigo, Mustonen, Ville, Oesper, Layla, Peifer, Martin, Peto, Myron, Raphael, Benjamin J., Rosebrock, Daniel, Salcedo, Adriana, Schumacher, Steven E., Sengupta, Subhajit, Shi, Ruian, Spiro, Oliver, Vázquez-García, Ignacio, Vembu, Shankar, Wheeler, David A., Yao, Xiaotong, Yuan, Ke, Wang, Wenyi, Morris, Quaid D., Spellman, Paul T., Wedge, David C., Van Loo, Peter

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Pertuzumab and trastuzumab for HER2-positive, metastatic biliary tract cancer (MyPathway): a multicentre, open-label, phase 2a, multiple basket study von Javle, Milind, Borad, Mitesh J, Azad, Nilofer S, Kurzrock, Razelle, Abou-Alfa, Ghassan K, George, Ben, Hainsworth, John, Meric-Bernstam, Funda, Swanton, Charles, Sweeney, Christopher J, Friedman, Claire F, Bose, Ron, Spigel, David R, Wang, Yong, Levy, Jonathan, Schulze, Katja, Cuchelkar, Vaikunth, Patel, Arisha, Burris, Howard

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Pertuzumab plus trastuzumab for HER2-amplified metastatic colorectal cancer (MyPathway): an updated report from a multicentre, open-label, phase 2a, multiple basket study von Meric-Bernstam, Funda, Hurwitz, Herbert, Raghav, Kanwal Pratap Singh, McWilliams, Robert R, Fakih, Marwan, VanderWalde, Ari, Swanton, Charles, Kurzrock, Razelle, Burris, Howard, Sweeney, Christopher, Bose, Ron, Spigel, David R, Beattie, Mary S, Blotner, Steven, Stone, Alyssa, Schulze, Katja, Cuchelkar, Vaikunth, Hainsworth, John

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Weed-induced crop yield loss: a new paradigm and new challenges von Horvath, David P., Clay, Sharon A., Swanton, Clarence J., Anderson, James V., Chao, Wun S.

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Cycling of extracellular DNA in the soil environment von Levy-Booth, David J., Campbell, Rachel G., Gulden, Robert H., Hart, Miranda M., Powell, Jeff R., Klironomos, John N., Pauls, K. Peter, Swanton, Clarence J., Trevors, Jack T., Dunfield, Kari E.

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Spatial and temporal diversity in genomic instability processes defines lung cancer evolution von de Bruin, Elza C., McGranahan, Nicholas, Mitter, Richard, Salm, Max, Wedge, David C., Yates, Lucy, Jamal-Hanjani, Mariam, Shafi, Seema, Murugaesu, Nirupa, Rowan, Andrew J., Grönroos, Eva, Muhammad, Madiha A., Horswell, Stuart, Gerlinger, Marco, Varela, Ignacio, Jones, David, Marshall, John, Voet, Thierry, Van Loo, Peter, Rassl, Doris M., Rintoul, Robert C., Janes, Sam M., Lee, Siow-Ming, Forster, Martin, Ahmad, Tanya, Lawrence, David, Falzon, Mary, Capitanio, Arrigo, Harkins, Timothy T., Lee, Clarence C., Tom, Warren, Teefe, Enock, Chen, Shann-Ching, Begum, Sharmin, Rabinowitz, Adam, Phillimore, Benjamin, Spencer-Dene, Bradley, Stamp, Gordon, Szallasi, Zoltan, Matthews, Nik, Stewart, Aengus, Campbell, Peter, Swanton, Charles

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Genetic prognostic and predictive markers in colorectal cancer von Walther, Axel, Johnstone, Elaine, Swanton, Charles, Midgley, Rachel, Tomlinson, Ian, Kerr, David

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Tracking the Evolution of Non–Small-Cell Lung Cancer von Jamal-Hanjani, Mariam, Wilson, Gareth A, McGranahan, Nicholas, Birkbak, Nicolai J, Watkins, Thomas B.K, Veeriah, Selvaraju, Shafi, Seema, Johnson, Diana H, Mitter, Richard, Rosenthal, Rachel, Salm, Max, Horswell, Stuart, Escudero, Mickael, Matthews, Nik, Rowan, Andrew, Chambers, Tim, Moore, David A, Turajlic, Samra, Xu, Hang, Lee, Siow-Ming, Forster, Martin D, Ahmad, Tanya, Hiley, Crispin T, Abbosh, Christopher, Falzon, Mary, Borg, Elaine, Marafioti, Teresa, Lawrence, David, Hayward, Martin, Kolvekar, Shyam, Panagiotopoulos, Nikolaos, Janes, Sam M, Thakrar, Ricky, Ahmed, Asia, Blackhall, Fiona, Summers, Yvonne, Shah, Rajesh, Joseph, Leena, Quinn, Anne M, Crosbie, Phil A, Naidu, Babu, Middleton, Gary, Langman, Gerald, Trotter, Simon, Nicolson, Marianne, Remmen, Hardy, Kerr, Keith, Chetty, Mahendran, Gomersall, Lesley, Fennell, Dean A, Nakas, Apostolos, Rathinam, Sridhar, Anand, Girija, Khan, Sajid, Russell, Peter, Ezhil, Veni, Ismail, Babikir, Irvin-Sellers, Melanie, Prakash, Vineet, Lester, Jason F, Kornaszewska, Malgorzata, Attanoos, Richard, Adams, Haydn, Davies, Helen, Dentro, Stefan, Taniere, Philippe, O’Sullivan, Brendan, Lowe, Helen L, Hartley, John A, Iles, Natasha, Bell, Harriet, Ngai, Yenting, Shaw, Jacqui A, Herrero, Javier, Szallasi, Zoltan, Schwarz, Roland F, Stewart, Aengus, Quezada, Sergio A, Le Quesne, John, Van Loo, Peter, Dive, Caroline, Hackshaw, Allan, Swanton, Charles

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Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing von Gerlinger, Marco, Rowan, Andrew J, Horswell, Stuart, Larkin, James, Endesfelder, David, Gronroos, Eva, Martinez, Pierre, Matthews, Nicholas, Stewart, Aengus, Tarpey, Patrick, Varela, Ignacio, Phillimore, Benjamin, Begum, Sharmin, McDonald, Neil Q, Butler, Adam, Jones, David, Raine, Keiran, Latimer, Calli, Santos, Claudio R, Nohadani, Mahrokh, Eklund, Aron C, Spencer-Dene, Bradley, Clark, Graham, Pickering, Lisa, Stamp, Gordon, Gore, Martin, Szallasi, Zoltan, Downward, Julian, Futreal, P. Andrew, Swanton, Charles

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Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution von Abbosh, Christopher, Birkbak, Nicolai J., Wilson, Gareth A., Jamal-Hanjani, Mariam, Constantin, Tudor, Salari, Raheleh, Le Quesne, John, Moore, David A., Veeriah, Selvaraju, Rosenthal, Rachel, Marafioti, Teresa, Kirkizlar, Eser, McGranahan, Nicholas, Ward, Sophia, Martinson, Luke, Riley, Joan, Fraioli, Francesco, Al Bakir, Maise, Grönroos, Eva, Zambrana, Francisco, Endozo, Raymondo, Bi, Wenya Linda, Fennessy, Fiona M., Sponer, Nicole, Johnson, Diana, Laycock, Joanne, Shafi, Seema, Czyzewska-Khan, Justyna, Rowan, Andrew, Chambers, Tim, Matthews, Nik, Hiley, Crispin, Lee, Siow Ming, Forster, Martin D., Ahmad, Tanya, Falzon, Mary, Borg, Elaine, Lawrence, David, Hayward, Martin, Kolvekar, Shyam, Panagiotopoulos, Nikolaos, Janes, Sam M., Thakrar, Ricky, Ahmed, Asia, Blackhall, Fiona, Naik, Ashwini, Ganguly, Apratim, Kareht, Stephanie, Shah, Rajesh, Joseph, Leena, Marie Quinn, Anne, Crosbie, Phil A., Naidu, Babu, Middleton, Gary, Langman, Gerald, Trotter, Simon, Nicolson, Marianne, Remmen, Hardy, Kerr, Keith, Chetty, Mahendran, Gomersall, Lesley, Fennell, Dean A., Nakas, Apostolos, Rathinam, Sridhar, Anand, Girija, Khan, Sajid, Russell, Peter, Ezhil, Veni, Ismail, Babikir, Irvin-Sellers, Melanie, Prakash, Vineet, Lester, Jason F., Kornaszewska, Malgorzata, Attanoos, Richard, Adams, Haydn, Davies, Helen, Oukrif, Dahmane, Akarca, Ayse U., Hartley, John A., Lowe, Helen L., Lock, Sara, Iles, Natasha, Bell, Harriet, Ngai, Yenting, Elgar, Greg, Szallasi, Zoltan, Schwarz, Roland F., Herrero, Javier, Stewart, Aengus, Quezada, Sergio A., Peggs, Karl S., Van Loo, Peter, Dive, Caroline, Lin, C. Jimmy, Rabinowitz, Matthew, Aerts, Hugo J. W. L., Hackshaw, Allan, Shaw, Jacqui A., Zimmermann, Bernhard G., Swanton, Charles

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Timing the Landmark Events in the Evolution of Clear Cell Renal Cell Cancer: TRACERx Renal von Mitchell, Thomas J., Turajlic, Samra, Rowan, Andrew, Nicol, David, Farmery, James H.R., O’Brien, Tim, Martincorena, Inigo, Tarpey, Patrick, Angelopoulos, Nicos, Yates, Lucy R., Butler, Adam P., Raine, Keiran, Stewart, Grant D., Challacombe, Ben, Fernando, Archana, Lopez, Jose I., Hazell, Steve, Chandra, Ashish, Chowdhury, Simon, Rudman, Sarah, Soultati, Aspasia, Stamp, Gordon, Fotiadis, Nicos, Pickering, Lisa, Au, Lewis, Spain, Lavinia, Lynch, Joanna, Stares, Mark, Teague, Jon, Maura, Francesco, Wedge, David C., Horswell, Stuart, Chambers, Tim, Litchfield, Kevin, Xu, Hang, Stewart, Aengus, Elaidi, Reza, Oudard, Stéphane, McGranahan, Nicholas, Csabai, Istvan, Gore, Martin, Futreal, P. Andrew, Larkin, James, Lynch, Andy G., Szallasi, Zoltan, Swanton, Charles, Campbell, Peter J.

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Evolution and clinical impact of co-occurring genetic alterations in advanced-stage EGFR-mutant lung cancers von Blakely, Collin M, Watkins, Thomas B K, Wu, Wei, Gini, Beatrice, Chabon, Jacob J, McCoach, Caroline E, McGranahan, Nicholas, Wilson, Gareth A, Birkbak, Nicolai J, Olivas, Victor R, Rotow, Julia, Maynard, Ashley, Wang, Victoria, Gubens, Matthew A, Banks, Kimberly C, Lanman, Richard B, Caulin, Aleah F, St John, John, Cordero, Anibal R, Giannikopoulos, Petros, Simmons, Andrew D, Mack, Philip C, Gandara, David R, Husain, Hatim, Doebele, Robert C, Riess, Jonathan W, Diehn, Maximilian, Swanton, Charles, Bivona, Trever G

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Cancer chromosomal instability: therapeutic and diagnostic challenges von McGranahan, Nicholas, Burrell, Rebecca A, Endesfelder, David, Novelli, Marco R, Swanton, Charles

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Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing von Gerlinger, Marco, Horswell, Stuart, Larkin, James, Rowan, Andrew J, Salm, Max P, Varela, Ignacio, Fisher, Rosalie, McGranahan, Nicholas, Matthews, Nicholas, Santos, Claudio R, Martinez, Pierre, Phillimore, Benjamin, Begum, Sharmin, Rabinowitz, Adam, Spencer-Dene, Bradley, Gulati, Sakshi, Bates, Paul A, Stamp, Gordon, Pickering, Lisa, Gore, Martin, Nicol, David L, Hazell, Steven, Futreal, P Andrew, Stewart, Aengus, Swanton, Charles

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Tracking Cancer Evolution Reveals Constrained Routes to Metastases: TRACERx Renal von Turajlic, Samra, Xu, Hang, Litchfield, Kevin, Rowan, Andrew, Chambers, Tim, Lopez, Jose I., Nicol, David, O’Brien, Tim, Larkin, James, Horswell, Stuart, Stares, Mark, Au, Lewis, Jamal-Hanjani, Mariam, Challacombe, Ben, Chandra, Ashish, Hazell, Steve, Eichler-Jonsson, Claudia, Soultati, Aspasia, Chowdhury, Simon, Rudman, Sarah, Lynch, Joanna, Fernando, Archana, Stamp, Gordon, Nye, Emma, Jabbar, Faiz, Spain, Lavinia, Lall, Sharanpreet, Guarch, Rosa, Falzon, Mary, Proctor, Ian, Pickering, Lisa, Gore, Martin, Watkins, Thomas B.K., Ward, Sophia, Stewart, Aengus, DiNatale, Renzo, Becerra, Maria F., Reznik, Ed, Hsieh, James J., Richmond, Todd A., Mayhew, George F., Hill, Samantha M., McNally, Catherine D., Jones, Carol, Rosenbaum, Heidi, Stanislaw, Stacey, Burgess, Daniel L., Alexander, Nelson R., Swanton, Charles

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Classifying the evolutionary and ecological features of neoplasms von Maley, Carlo C., Aktipis, Athena, Graham, Trevor A., Sottoriva, Andrea, Boddy, Amy M., Janiszewska, Michalina, Silva, Ariosto S., Gerlinger, Marco, Yuan, Yinyin, Pienta, Kenneth J., Anderson, Karen S., Gatenby, Robert, Swanton, Charles, Posada, David, Wu, Chung-I, Schiffman, Joshua D., Hwang, E. Shelley, Polyak, Kornelia, Anderson, Alexander R. A., Brown, Joel S., Greaves, Mel, Shibata, Darryl

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