In Vitro Approach to Assess the Potential for Risk of Idiosyncratic Adverse Reactions Caused by Candidate Drugs von Thompson, Richard A, Isin, Emre M, Li, Yan, Weidolf, Lars, Page, Ken, Wilson, Ian, Swallow, Steve, Middleton, Brian, Stahl, Simone, Foster, Alison J, Dolgos, Hugues, Weaver, Richard, Kenna, J. Gerry

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The impact of radiochemistry in drug projects: The use of C‐14 label in the AZD8529, AZD7325, and AZD6280 projects von Kingston, Lee, Gu, Chungang, Guo, Jian, Swallow, Steve, Elmore, Charles S.

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Fluorine in medicinal chemistry von Purser, Sophie, Moore, Peter R, Swallow, Steve, Gouverneur, Véronique

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Discovery of a Potent and Selective Oral Inhibitor of ERK1/2 (AZD0364) That Is Efficacious in Both Monotherapy and Combination Therapy in Models of Nonsmall Cell Lung Cancer (NSCLC... von Ward, Richard A, Anderton, Mark J, Bethel, Paul, Breed, Jason, Cook, Calum, Davies, Emma J, Dobson, Andrew, Dong, Zhiqiang, Fairley, Gary, Farrington, Paul, Feron, Lyman, Flemington, Vikki, Gibbons, Francis D, Graham, Mark A, Greenwood, Ryan, Hanson, Lyndsey, Hopcroft, Philip, Howells, Rachel, Hudson, Julian, James, Michael, Jones, Clifford D, Jones, Christopher R, Li, Yongchao, Lamont, Scott, Lewis, Richard, Lindsay, Nicola, McCabe, James, McGuire, Thomas, Rawlins, Philip, Roberts, Karen, Sandin, Linda, Simpson, Iain, Swallow, Steve, Tang, Jia, Tomkinson, Gary, Tonge, Michael, Wang, Zhenhua, Zhai, Baochang

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Discovery of Second Generation Reversible Covalent DPP1 Inhibitors Leading to an Oxazepane Amidoacetonitrile Based Clinical Candidate (AZD7986) von Doyle, Kevin, Lönn, Hans, Käck, Helena, Van de Poël, Amanda, Swallow, Steve, Gardiner, Philip, Connolly, Stephen, Root, James, Wikell, Cecilia, Dahl, Göran, Stenvall, Kristina, Johannesson, Petra

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Structure-Guided Discovery of Potent and Selective Inhibitors of ERK1/2 from a Modestly Active and Promiscuous Chemical Start Point von Ward, Richard A, Bethel, Paul, Cook, Calum, Davies, Emma, Debreczeni, Judit E, Fairley, Gary, Feron, Lyman, Flemington, Vikki, Graham, Mark A, Greenwood, Ryan, Griffin, Nicola, Hanson, Lyndsey, Hopcroft, Philip, Howard, Tina D, Hudson, Julian, James, Michael, Jones, Clifford D, Jones, Christopher R, Lamont, Scott, Lewis, Richard, Lindsay, Nicola, Roberts, Karen, Simpson, Iain, St-Gallay, Steve, Swallow, Steve, Tang, Jia, Tonge, Michael, Wang, Zhenhua, Zhai, Baochang

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Aortic Binding of AZD5248: Mechanistic Insight and Reactivity Assays To Support Lead Optimzation von Bragg, Ryan A, Brocklehurst, Simon, Gustafsson, Frida, Goodman, James, Hickling, Kevin, MacFaul, Philip A, Swallow, Steve, Tugwood, Jonathan

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Abstract 1647: Discovery of AZD0364, a potent and selective oral inhibitor of ERK1/2 that is efficacious in both monotherapy and combination therapy in models of NSCLC von Simpson, Iain, Anderton, Mark J., Andrews, David M., Breed, Jason, Davies, Emma, Debreczeni, Judit E., Flemington, Vikki, Gibbons, Francis D., Graham, Mark A., Hopcroft, Philip, Howard, Tina, Hudson, Julian, Jones, Clifford D., Jones, Christopher, Lindsay, Nicola, Pease, J Elizabeth, Rawlins, Philip, Roberts, Karen, Swallow, Steve, St-Gallay, Steve, Tonge, Michael E., Ward, Richard A.

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Strategies to improve in vivo toxicology outcomes for basic candidate drug molecules von Luker, Tim, Alcaraz, Lilian, Chohan, Kamaldeep K., Blomberg, Niklas, Brown, Dearg S., Butlin, Roger J., Elebring, Thomas, Griffin, Andrew M., Guile, Simon, St-Gallay, Stephen, Swahn, Britt-Marie, Swallow, Steve, Waring, Michael J., Wenlock, Mark C., Leeson, Paul D.

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Novel and Versatile Synthesis of Disubstituted 1,2-Dihydro-1,2,4-triazol-3-ones von Graham, Mark A, Bethel, Paul A, Burgess, Jonathan, Fairley, Gary, Glossop, Steve C, Greenwood, Ryan D. R, Jones, Clifford D, Lovell, Scott, Swallow, Steve

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A pharma-wide approach to address the genotoxicity prediction of primary aromatic amines von Patel, Mukesh, Kranz, Michael, Munoz-Muriedas, Jordi, Harvey, James S., Giddings, Amanda, Swallow, Steve, Fellows, Mick, Naven, Russell, Werner, Anne-Laure, Yeo, David J., Bringezu, Frank, Wichard, Joerg, Sutter, Andreas, Glowienke, Susanne, Whitehead, Lewis, Selby, Matt, Reuberson, James, Atienzar, Franck, Gerets, Helga, Kenyon, Michelle O., Dobo, Krista L., Walter, Magnus W., Jolly, Robert A., Amberg, Alexander, Spirkl, Hans-Peter, Muster, Wolfgang, Van Gompel, Jacques

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The discovery of N-cyclopropyl-4-methyl-3-[6-(4-methylpiperazin-1-yl)-4-oxoquinazolin-3(4H)-yl]benzamide (AZD6703), a clinical p38α MAP kinase inhibitor for the treatment of inflam... von Brown, Dearg S., Cumming, John G., Bethel, Paul, Finlayson, Jonathan, Gerhardt, Stefan, Nash, Ian, Pauptit, Richard A., Pike, Kurt G., Reid, Alan, Snelson, Wendy, Swallow, Steve, Thompson, Caroline

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The discovery of N-cyclopropyl-4-methyl-3-[6-(4-methylpiperazin-1-yl)-4-oxoquinazol i n-3(4H)-yl]benzamide (AZD6703), a clinical p38I- MAP kinase inhibitor for the treatment of inf... von Brown, Dearg S, Cumming, John G, Bethel, Paul, Finlayson, Jonathan, Gerhardt, Stefan, Nash, Ian, Pauptit, Richard A, Pike, Kurt G, Reid, Alan, Snelson, Wendy, Swallow, Steve, Thompson, Caroline

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Predictive secondary pharmacology: Concepts and application to drug discovery von Rolf, Michael G., Swallow, Steve, Engkvist, Ola, Bowes, Joanne, Valentin, Jean-Pierre

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Carla Bley "The lost chords find Paolo Fresu"

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ChemInform Abstract: Novel and Versatile Synthesis of Disubstituted 1,2-Dihydro-1,2,4-triazol-3-ones von Graham, Mark A., Bethel, Paul A., Burgess, Jonathan, Fairley, Gary, Glossop, Steve C., Greenwood, Ryan D. R., Jones, Clifford D., Lovell, Scott, Swallow, Steve

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December von Swallow, Steve

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By the way von Bley, Paul, Giuffre, Jimmy <1921-2008>, Swallow, Steve

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ChemInform Abstract: Fluorine in Medicinal Chemistry von Purser, Sophie, Moore, Peter R., Swallow, Steve, Gouverneur, Veronique

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Endless melody von Bley, Paul, Swallow, Steve

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