Discovery of novel bacterial queuine salvage enzymes and pathways in human pathogens von Yuan, Yifeng, Zallot, Rémi, Grove, Tyler L., Payan, Daniel J., Martin-Verstraete, Isabelle, Šepić, Sara, Balamkundu, Seetharamsingh, Neelakandan, Ramesh, Gadi, Vinod K., Liu, Chuan-Fa, Swairjo, Manal A., Dedon, Peter C., Almo, Steven C., Gerlt, John A., de Crécy-Lagard, Valérie

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Structural basis of Qng1-mediated salvage of the micronutrient queuine from queuosine-5'-monophosphate as the biological substrate von Hung, Shr-Hau, Elliott, Gregory I, Ramkumar, Thakku R, Burtnyak, Lyubomyr, McGrenaghan, Callum J, Alkuzweny, Sana, Quaiyum, Samia, Iwata-Reuyl, Dirk, Pan, Xiaobei, Green, Brian D, Kelly, Vincent P, de Crécy-Lagard, Valérie, Swairjo, Manal A

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Structure and mechanism of a bacterial t6A biosynthesis system von Luthra, Amit, Swinehart, William, Bayooz, Susan, Phan, Phuc, Stec, Boguslaw, Iwata-Reuyl, Dirk, Swairjo, Manal A

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Conformational communication mediates the reset step in t6A biosynthesis von Luthra, Amit, Paranagama, Naduni, Swinehart, William, Bayooz, Susan, Phan, Phuc, Quach, Vanessa, Schiffer, Jamie M, Stec, Boguslaw, Iwata-Reuyl, Dirk, Swairjo, Manal A

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7-Deazaguanines in DNA: functional and structural elucidation of a DNA modification system von Gedara, Samanthi Herath, Wood, Evan, Gustafson, Andrew, Liang, Cui, Hung, Shr-Hau, Savage, Joshua, Phan, Phuc, Luthra, Amit, de Crécy-Lagard, Valérie, Dedon, Peter, Swairjo, Manal A, Iwata-Reuyl, Dirk

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Specificity in the biosynthesis of the universal tRNA nucleoside N6-threonylcarbamoyl adenosine (t6A)-TsaD is the gatekeeper von Swinehart, William, Deutsch, Christopher, Sarachan, Kathryn L, Luthra, Amit, Bacusmo, Jo Marie, de Crécy-Lagard, Valérie, Swairjo, Manal A, Agris, Paul F, Iwata-Reuyl, Dirk

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Predicting the capsid architecture of phages from metagenomic data von Lee, Diana Y., Bartels, Caitlin, McNair, Katelyn, Edwards, Robert A., Swairjo, Manal A., Luque, Antoni

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Structure-based design of guanosine analogue inhibitors targeting GTP cyclohydrolase IB towards a new class of antibiotics von Samaan, George N., Paranagama, Naduni, Haque, Ayesha, Hecht, David A., Swairjo, Manal A., Purse, Byron W.

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Mechanism and catalytic strategy of the prokaryotic-specific GTP cyclohydrolase-IB von Paranagama, Naduni, Bonnett, Shilah A, Alvarez, Jonathan, Luthra, Amit, Stec, Boguslaw, Gustafson, Andrew, Iwata-Reuyl, Dirk, Swairjo, Manal A

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Specificity in the biosynthesis of the universal tRNA nucleoside N 6 -threonylcarbamoyl adenosine (t 6 A)-TsaD is the gatekeeper von Swinehart, William, Deutsch, Christopher, Sarachan, Kathryn L, Luthra, Amit, Bacusmo, Jo Marie, de Crécy-Lagard, Valérie, Swairjo, Manal A, Agris, Paul F, Iwata-Reuyl, Dirk

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The universal YrdC/Sua5 family is required for the formation of threonylcarbamoyladenosine in tRNA von El Yacoubi, Basma, Lyons, Benjamin, Cruz, Yulien, Reddy, Robert, Nordin, Brian, Agnelli, Fabio, Williamson, James R., Schimmel, Paul, Swairjo, Manal A., de Crécy-Lagard, Valérie

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Inhibitor potency varies widely among tumor-relevant human isocitrate dehydrogenase 1 mutants von Avellaneda Matteo, Diego, Wells, Grace A, Luna, Lucas A, Grunseth, Adam J, Zagnitko, Olga, Scott, David A, Hoang, An, Luthra, Amit, Swairjo, Manal A, Schiffer, Jamie M, Sohl, Christal D

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Crystal structure of the archaeosine synthase QueF‐like—Insights into amidino transfer and tRNA recognition by the tunnel fold von Mei, Xianghan, Alvarez, Jonathan, Bon Ramos, Adriana, Samanta, Uttamkumar, Iwata‐Reuyl, Dirk, Swairjo, Manal A.

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Diversity of Archaeosine Synthesis in Crenarchaeota von Phillips, Gabriela, Swairjo, Manal A, Gaston, Kirk W, Bailly, Marc, Limbach, Patrick A, Iwata-Reuyl, Dirk, de Crécy-Lagard, Valérie

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Zinc-Independent Folate Biosynthesis: Genetic, Biochemical, and Structural Investigations Reveal New Metal Dependence for GTP Cyclohydrolase IB von SANKARAN, Banumathi, BONNETT, Shilah A, SWAIRJO, Manal A, SHAH, Kinjal, GABRIEL, Scott, REDDY, Robert, SCHIMMEL, Paul, RODIONOV, Dmitry A, DE CRECY-LAGARD, Valérie, HELMANN, John D, IWATA-REUYL, Dirk

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Structural Basis of Biological Nitrile Reduction von Chikwana, Vimbai M., Stec, Boguslaw, Lee, Bobby W.K., de Crécy-Lagard, Valérie, Iwata-Reuyl, Dirk, Swairjo, Manal A.

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Protection of the Queuosine Biosynthesis Enzyme QueF from Irreversible Oxidation by a Conserved Intramolecular Disulfide von Mohammad, Adeba, Bon Ramos, Adriana, Lee, Bobby W K, Cohen, Spencer W, Kiani, Maryam K, Iwata-Reuyl, Dirk, Stec, Boguslaw, Swairjo, Manal A

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Discovery and Characterization of an Amidinotransferase Involved in the Modification of Archaeal tRNA von Phillips, Gabriela, Chikwana, Vimbai M., Maxwell, Adrienne, El-Yacoubi, Basma, Swairjo, Manal A., Iwata-Reuyl, Dirk, de Crécy-Lagard, Valérie

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From Cyclohydrolase to Oxidoreductase: Discovery of Nitrile Reductase Activity in a Common Fold von Van Lanen, Steven G., Reader, John S., Swairjo, Manal A., de Crécy-Lagard, Valérie, Lee, Bobby, Iwata-Reuyl, Dirk, Benkovic, Stephen J.

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Discovery of a New Prokaryotic Type I GTP Cyclohydrolase Family von El Yacoubi, Basma, Bonnett, Shilah, Anderson, Jessica N., Swairjo, Manal A., Iwata-Reuyl, Dirk, de Crécy-Lagard, Valérie

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