CD4 memory has a hierarchical structure created by requirements for infection-derived signals at an effector checkpoint von Swain, Susan L

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PSGL-1 Is an Immune Checkpoint Regulator that Promotes T Cell Exhaustion von Tinoco, Roberto, Carrette, Florent, Barraza, Monique L., Otero, Dennis C., Magaña, Jonathan, Bosenberg, Marcus W., Swain, Susan L., Bradley, Linda M.

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IL-6-mediated environmental conditioning of defective Th1 differentiation dampens antitumour immune responses in old age von Tsukamoto, Hirotake, Senju, Satoru, Matsumura, Keiko, Swain, Susan L., Nishimura, Yasuharu

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Multifunctional CD4 Cells Expressing Gamma Interferon and Perforin Mediate Protection against Lethal Influenza Virus Infection von Brown, Deborah M., Lee, Sarah, Garcia-Hernandez, Maria de la Luz, Swain, Susan L.

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Memory CD4 T cell-derived IL-2 synergizes with viral infection to exacerbate lung inflammation von McKinstry, K Kai, Alam, Fahmida, Flores-Malavet, Valeria, Nagy, Mate Z, Sell, Stewart, Cooper, Andrea M, Swain, Susan L, Strutt, Tara M

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IL-10 Deficiency Unleashes an Influenza-Specific Th17 Response and Enhances Survival against High-Dose Challenge von McKinstry, K. Kai, Strutt, Tara M, Buck, Amanda, Curtis, Jonathan D, Dibble, John P, Huston, Gail, Tighe, Michael, Hamada, Hiromasa, Sell, Stewart, Dutton, Richard W, Swain, Susan L

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Cytotoxic CD4 development requires CD4 effectors to concurrently recognize local antigen and encounter type I IFN-induced IL-15 von Devarajan, Priyadharshini, Vong, Allen M., Castonguay, Catherine H., Silverstein, Noah J., Kugler-Umana, Olivia, Bautista, Bianca L., Kelly, Karen A., Luban, Jeremy, Swain, Susan L.

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IL-6 Production by TLR-Activated APC Broadly Enhances Aged Cognate CD4 Helper and B Cell Antibody Responses In Vivo von Brahmakshatriya, Vinayak, Kuang, Yi, Devarajan, Priyadharshini, Xia, Jingya, Zhang, Wenliang, Vong, Allen Minh, Swain, Susan L

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Memory CD4⁺ T-cell–mediated protection depends on secondary effectors that are distinct from and superior to primary effectors von Strutt, Tara M, McKinstry, K. Kai, Kuang, Yi, Bradley, Linda M, Swain, Susan L

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Cytotoxic CD4 development requires CD4 effectors to concurrently recognize local antigen and encounter type I IFN-induced IL-15 von Devarajan, Priyadharshini, Vong, Allen M., Castonguay, Catherine H., Silverstein, Noah J., Kugler-Umana, Olivia, Bautista, Bianca L., Kelly, Karen A., Luban, Jeremy, Swain, Susan L.

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IL-7 promotes the transition of CD4 effectors to persistent memory cells von Li, JiChu, Huston, Gail, Swain, Susan L

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Age-associated increase in lifespan of naïve CD4 T cells contributes to T-cell homeostasis but facilitates development of functional defects von Tsukamoto, Hirotake, Clise-Dwyer, Karen, Huston, Gail E, Duso, Debra K, Buck, Amanda L, Johnson, Lawrence L, Haynes, Laura, Swain, Susan L

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Expanding roles for CD4+ T cells in immunity to viruses von Swain, Susan L., McKinstry, K. Kai, Strutt, Tara M.

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PSGL-1 Is an Immune Checkpoint Regulator that Promotes T Cell Exhaustion von Tinoco, Roberto, Carrette, Florent, Barraza, Monique L., Otero, Dennis C., Magaña, Jonathan, Bosenberg, Marcus W., Swain, Susan L., Bradley, Linda M.

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New Insights into the Generation of CD4 Memory May Shape Future Vaccine Strategies for Influenza von Devarajan, Priyadharshini, Bautista, Bianca, Vong, Allen M, McKinstry, Karl Kai, Strutt, Tara M, Swain, Susan L

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Pathogen Recognition by CD4 Effectors Drives Key Effector and Most Memory Cell Generation Against Respiratory Virus von Devarajan, Priyadharshini, Jones, Michael C, Kugler-Umana, Olivia, Vong, Allen M, Xia, Jingya, Swain, Susan L

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CD4 T Cell Memory Derived from Young Naive Cells Functions Well into Old Age, but Memory Generated from Aged Naive Cells Functions Poorly von Haynes, Laura, Eaton, Sheri M., Burns, Eve M., Randall, Troy D., Swain, Susan L.

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Krüppel‐like factor 4 (KLF4) directly regulates proliferation in thymocyte development and IL‐17 expression during Th17 differentiation von An, Jie, Golech, Susanne, Klaewsongkram, Jettanong, Zhang, Yongqing, Subedi, Kalpana, Huston, Gail E., Wood, William H., Wersto, Robert P., Becker, Kevin G., Swain, Susan L., Weng, Nanping

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Original Antigenic Sin: Friend or Foe in Developing a Broadly Cross-Reactive Vaccine to Influenza? von Devarajan, Priyadharshini, Swain, Susan L.

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Influenza Vaccine-Induced CD4 Effectors Require Antigen Recognition at an Effector Checkpoint to Generate CD4 Lung Memory and Antibody Production von Xia, Jingya, Kuang, Yi, Liang, Jialing, Jones, Michael, Swain, Susan L.

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