Prediction of pKa Values for Druglike Molecules Using Semiempirical Quantum Chemical Methods von Jensen, Jan H, Swain, Christopher J, Olsen, Lars

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Prediction of pK a Values for Druglike Molecules Using Semiempirical Quantum Chemical Methods von Jensen, Jan H., Swain, Christopher J., Olsen, Lars

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Molecular Docking with Open Access Software: Development of an Online Laboratory Handbook and Remote Workflow for Chemistry and Pharmacy Master’s Students to Undertake Computer-Aid... von Clent, Bethanie A, Wang, Yuhang, Britton, Hugh C, Otto, Frank, Swain, Christopher J, Todd, Matthew H, Wilden, Jonathan D, Tabor, Alethea B

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Bifunctional crosslinking ligands for transthyretin von Mangione, P. Patrizia, Deroo, Stéphanie, Ellmerich, Stephan, Bellotti, Vittorio, Kolstoe, Simon, Wood, Stephen P., Robinson, Carol V., Smith, Martin D., Tennent, Glenys A., Broadbridge, Robert J., Council, Claire E., Thurston, Joanne R., Steadman, Victoria A., Vong, Antonio K., Swain, Christopher J., Pepys, Mark B., Taylor, Graham W.

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Distinct Mechanism for Antidepressant Activity by Blockade of Central Substance P Receptors von Kramer, Mark S., Cutler, Neal, Feighner, John, Shrivastava, Ram, Carman, John, Sramek, John J., Reines, Scott A., Liu, Guanghan, Snavely, Duane, Wyatt-Knowles, Edwina, Hale, Jeffrey J., Mills, Sander G., MacCoss, Malcolm, Swain, Christopher J., Harrison, Timothy, Hill, Raymond G., Hefti, Franz, Scolnick, Edward M., Cascieri, Margaret A., Chicchi, Gary G., Sadowski, Sharon, Williams, Angela R., Hewson, Louise, Smith, David, Carlson, Emma J., Hargreaves, Richard J., Nadia M. J. Rupniak

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Open Source Antibiotics: Simple Diarylimidazoles Are Potent against Methicillin-Resistant Staphylococcus aureus von Klug, Dana M, Tse, Edwin G, Silva, Daniel G, Cao, Yafeng, Charman, Susan A, Chauhan, Jyoti, Crighton, Elly, Dichiara, Maria, Drake, Chris, Drewry, David, da Silva Emery, Flavio, Ferrins, Lori, Graves, Lee, Hopkins, Emily, Kresina, Thomas A C, Lorente-Macías, Álvaro, Perry, Benjamin, Phipps, Richard, Quiroga, Bruno, Quotadamo, Antonio, Sabatino, Giada N, Sama, Anthony, Schätzlein, Andreas, Simpson, Quillon J, Steele, Jonathan, Shanu-Wilson, Julia, Sjö, Peter, Stapleton, Paul, Swain, Christopher J, Vaideanu, Alexandra, Xie, Huanxu, Zuercher, William, Todd, Matthew H

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Escaping from Flatland: Antimalarial Activity of sp 3 -Rich Bridged Pyrrolidine Derivatives von Cox, Brian, Duffy, James, Zdorichenko, Victor, Bellanger, Corentin, Hurcum, Jessica, Laleu, Benoît, Booker-Milburn, Kevin I, Elliott, Luke D, Robertson-Ralph, Michael, Swain, Christopher J, Bishop, Stephen J, Hallyburton, Irene, Anderson, Mark

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Escaping from Flatland: Antimalarial Activity of sp3‑Rich Bridged Pyrrolidine Derivatives von Cox, Brian, Duffy, James, Zdorichenko, Victor, Bellanger, Corentin, Hurcum, Jessica, Laleu, Benoît, Booker-Milburn, Kevin I, Elliott, Luke D, Robertson-Ralph, Michael, Swain, Christopher J, Bishop, Stephen J, Hallyburton, Irene, Anderson, Mark

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Synthesis and structure-activity relationships of 8-azabicyclo[3.2.1]octane benzylamine NK1 antagonists von THOMSON, Christopher G, CARLSON, Emma, CHICCHI, Gary G, KULAGOWSKI, Janusz J, KURTZ, Marc M, SWAIN, Christopher J, TSAO, Kwei-Lan C, WHEELDON, Alan

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Stereocontrolled Syntheses of Epimeric 3-Aryl-6-phenyl-1-oxa-7-azaspiro[4.5]decane NK-1 Receptor Antagonist Precursors von Kulagowski, Janusz J, Curtis, Neil R, Swain, Christopher J, Williams, Brian J

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Evidence for an enhancement of excitatory transmission in adult CNS by Wnt signaling pathway modulation von Beaumont, Vahri, Thompson, Sally-Anne, Choudhry, Fahd, Nuthall, Hugh, Glantschnig, Helmut, Lipfert, Lorraine, David, Gabriela R., Swain, Christopher J., McAllister, George, Munoz-Sanjuan, Ignacio

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4,4-Disubstituted cyclohexylamine NK1 receptor antagonists II von COOPER, Laura C, CARLSON, Emma J, RYCROFT, Wayne, TSAO, Kwei-Lan, SWAIN, Christopher J, CASTRO, Jose L, CHICCHI, Gary G, DINNELL, Kevin, DI SALVO, Jerry, ELLIOTT, Jason M, HOLLINGWORTH, Gregory J, KURTZ, Marc M, RIDGILL, Mark P

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Spirocyclic NK1 antagonists II: [4.5]-Spiroethers von WILLIAMS, Brian J, CASCIERI, Margaret A, CHICCHI, Gary G, HARRISON, Timothy, OWENS, Andrew P, OWEN, Simon N, RUPNIAK, Nadia M. J, TATTERSALL, David F, WILLIAMS, Angela, SWAIN, Christopher J

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Identification and optimisation of 5-amino-7-aryldihydro-1,4-diazepines as 5-HT2A ligands von SWAIN, Christopher J, TERAN, Ana, MAROTO, Marta, CABELLO, Angeles

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2-Aryl indole NK1 receptor antagonists : Optimisation of indole substitution von COOPER, Laura C, CHICCHI, Gary G, WATT, Alan P, WILLIAMS, Angela R, SWAIN, Christopher J, DINNELL, Kevin, ELLIOTT, Jason M, HOLLINGWORTH, Gregory J, KURTZ, Mare M, LOCKER, Karen L, MORRISON, Denise, SHAW, Duncan E, TSAO, Kwei-Lan

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An Orally Active, Water-Soluble Neurokinin-1 Receptor Antagonist Suitable for Both Intravenous and Oral Clinical Administration von Harrison, Timothy, Owens, Andrew P, Williams, Brian J, Swain, Christopher J, Williams, Angela, Carlson, Emma J, Rycroft, Wayne, Tattersall, F. David, Cascieri, Margaret A, Chicchi, Gary G, Sadowski, Sharon, Rupniak, Nadia M. J, Hargreaves, Richard J

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Prediction of p K a Values for Druglike Molecules Using Semiempirical Quantum Chemical Methods von Jensen, Jan H., Swain, Christopher J., Olsen, Lars

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In vitro and in vivo predictors of the anti-emetic activity of tachykinin NK1 receptor antagonists von RUPNIAK, N. M. J, TATTERSALL, F. D, MACCOSS, M, SEWARD, E, HUSCROFT, I, OWEN, S, SWAIN, C. J, HILL, R. G, HARGREAVES, R. J, WILLIAMS, A. R, RYCROFT, W, CARLSON, E. J, CASCIERI, M. A, SADOWSKI, S, BER, E, HALE, J. J, MILLS, S. G

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2-Aryl indole NK1 receptor antagonists : Optimisation of the 2-aryl ring and the indole nitrogen substituent von DINNELL, Kevin, CHICCHI, Gary G, SWAIN, Christopher J, DHAR, Madhumeeta J, ELLIOTT, Jason M, HOLLINGWORTH, Gregory J, KURTZ, Marc M, RIDGILL, Mark P, RYCROFT, Wayne, TSAO, Kwei-Lan, WILLIAMS, Angela R

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Escaping from Flatland: Antimalarial Activity of sp(3)-Rich Bridged Pyrrolidine Derivatives von Cox, Brian, Duffy, James, Zdorichenko, Victor, Bellanger, Corentin, Hurcum, Jessica, Laleu, Benoit, Booker-Milburn, Kevin, Elliott, Luke D., Robertson-Ralph, Michael, Swain, Christopher J., Bishop, Stephen J., Hallyburton, Irene, Anderson, Mark

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