A novel, highly potent and selective phosphodiesterase-9 inhibitor for the treatment of sickle cell disease von McArthur, James G, Svenstrup, Niels, Chen, Chunsheng, Fricot, Aurelie, Carvalho, Caroline, Nguyen, Julia, Nguyen, Phong, Parachikova, Anna, Abdulla, Fuad, Vercellotti, Gregory M, Hermine, Olivier, Edwards, Dave, Ribeil, Jean-Antoine, Belcher, John D, Maciel, Thiago T

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The Organic Chemistry of 1,3-Dithiole-2-thione-4,5-dithiolate (DMIT) von Svenstrup, Niels, Becher, Jan

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PGN-EDODM1: Preclinical Data Supporting the Development of an Enhanced Delivery Oligonucleotide (EDO) for the Treatment of Myotonic Dystrophy Type 1 (DM1) (S48.001) von Holland, Ashling, Klein, Arnaud, Godfrey, Caroline, Svenstrup, Niels, Larkindale, Jane, Bracegirdle, Sonia, Furling, Denis, Goyal, Jaya

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PGN-EDO51: Preclinical Data Supporting the Development of an Enhanced Delivery Oligonucleotide (EDO) for the Treatment of Duchenne Muscular Dystrophy (DMD) (P3-8.002) von Holland, Ashling, Godfrey, Caroline, Lonkar, Pallavi, Svenstrup, Niels, Larkindale, Jane, McArthur, James, Bracegirdle, Sonia, Goyal, Jaya

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PGN-EDO51, an Enhanced Delivery Oligonucleotide (EDO) for the Treatment of Duchenne Muscular Dystrophy (DMD): Results of a Phase 1 Study in Healthy Volunteers (P3-8.004) von Mellion, Michelle, Larkindale, Jane, Lonkar, Pallavi, Goyal, Jaya, Holland, Ashling, Foy, Jeff, Garg, Brijesh, Yu, Shaoxia, Frank, Anthony, Abbott, Chris, Svenstrup, Niels, Cormier, Jennifer, Vacca, Sarah, McArthur, James

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Sequential Functionalisation of Bis-Protected Tetrathiafulvalene-dithiolates von Simonsen, Klaus B., Svenstrup, Niels, Lau, Jesper, Simonsen, Ole, Mørk, Pernille, Kristensen, Gitte J., Becher, Jan

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Biological Characterization of Novel Inhibitors of the Gram-Positive DNA Polymerase IIIC Enzyme von KUHL, Alexander, SVENSTRUP, Niels, HAEBICH, Dieter, EHLERT, Kerstin, LADEL, Christoph, OTTENEDER, Michael, BINAS, Annegret, SCHIFFER, Guido, BRANDS, Michael, LAMPE, Thomas, ZIEGELBAUER, Karl, RÜBSAMEN-WAIGMANN, Helga

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The Chemistry of TTFTT; 1: New Efficient Synthesis and Reactions of Tetrathiafulvalene-2,3,6,7-tetrathiolate (TTFTT): An Important Building Block in TTF-Syntheses von Svenstrup, Niels, Rasmussen, Karen Margrethe, Hansen, Thomas Kruse, Becher, Jan

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A Magnesium-Based Diastereoselective Preparation of Pyridylic 1,3-Amino Alcohols Using the tert-Butyl Sulfinamide Auxiliary von Fjelbye, Kasper, Svenstrup, Niels, Püschl, Ask

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A small molecule activator of Nav1.1 channels increases fast‐spiking interneuron excitability and GABAergic transmission in vitro and has anti‐convulsive effects in vivo von Frederiksen, Kristen, Lu, Dunguo, Yang, Jinhui, Jensen, Henrik Sindal, Bastlund, Jesper Frank, Larsen, Peter Hjørringgaard, Liu, Henry, Crestey, François, Dekermendjian, Kim, Badolo, Lassina, Laursen, Morten, Hougaard, Charlotte, Yang, Charles, Svenstrup, Niels, Grunnet, Morten

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A Novel, Highly Potent and Selective PDE9 Inhibitor for the Treatment of Sickle Cell Disease von McArthur, James G, Maciel, Thiago, Chen, Chunsheng, Fricot, Aurelie, Kobayashi, Dione, Nguyen, Julia, Nguyen, Phong, Parachova, Anna, Abdulla, Fuad, Vercellotti, Gregory M., Svenstrup, Niels, Belcher, John D

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The Grasshopper: A Novel Model for Assessing Vertebrate Brain Uptake von Andersson, Olga, Hansen, Steen Honoré, Hellman, Karin, Olsen, Line Rørbæk, Andersson, Gunnar, Badolo, Lassina, Svenstrup, Niels, Nielsen, Peter Aadal

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A small molecule activator of Na v 1.1 channels increases fast-spiking interneuron excitability and GABAergic transmission in vitro and has anti-convulsive effects in vivo von Frederiksen, Kristen, Lu, Dunguo, Yang, Jinhui, Jensen, Henrik Sindal, Bastlund, Jesper Frank, Larsen, Peter Hjørringgaard, Liu, Henry, Crestey, François, Dekermendjian, Kim, Badolo, Lassina, Laursen, Morten, Hougaard, Charlotte, Yang, Charles, Svenstrup, Niels, Grunnet, Morten

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A small molecule activator of Nav1.1 channels increases fast-spiking interneuron excitability and GABAergic transmission inￂ vitro and has anti-convulsive effects inￂ vivo von Frederiksen, Kristen, Lu, Dunguo, Yang, Jinhui, Jensen, Henrik Sindal, Bastlund, Jesper Frank, Larsen, Peter Hjørringgaard, Liu, Henry, Crestey, François, Dekermendjian, Kim, Badolo, Lassina, Laursen, Morten, Hougaard, Charlotte, Yang, Charles, Svenstrup, Niels, Grunnet, Morten

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A Pyrazole to Furan Rearrangement. Thermolysis of 5-Azido-4-formylpyrazoles von Svenstrup, Niels, Simonsen, Klaus B, Thorup, Niels, Brodersen, Jørgen, Dehaen, Wim, Becher, Jan

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Subtype-Specific Agonists for NMDA Receptor Glycine Binding Sites von Maolanon, Alex R, Risgaard, Rune, Wang, Shuang-Yan, Snoep, Yoran, Papangelis, Athanasios, Yi, Feng, Holley, David, Barslund, Anne F, Svenstrup, Niels, Hansen, Kasper B, Clausen, Rasmus P

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Improved synthesis of antibacterial 3-substituted 6-anilinouracils von Svenstrup, Niels, Kuhl, Alexander, Ehlert, Kerstin, Häbich, Dieter

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Pyrrolidinedione derivatives as antibacterial agents with a novel mode of action von Pohlmann, Jens, Lampe, Thomas, Shimada, Mitsuyuki, Nell, Peter G., Pernerstorfer, Josef, Svenstrup, Niels, Brunner, Nina A., Schiffer, Guido, Freiberg, Christoph

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Identification and Electrophysiological Evaluation of 2‑Methylbenzamide Derivatives as Nav1.1 Modulators von Crestey, François, Frederiksen, Kristen, Jensen, Henrik S, Dekermendjian, Kim, Larsen, Peter H, Bastlund, Jesper F, Lu, Dunguo, Liu, Henry, Yang, Charles R, Grunnet, Morten, Svenstrup, Niels

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PDE9 INHIBITORS FOR TREATING SICKLE CELL DISEASE von SVENSTRUP, Niels

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