105. Intranasal 5-MeO-DMT: Safety, PK and Effect on Altered States of Consciousness in Healthy Volunteers von Rucker, James, Seynaeve, Mathieu, Young, Allan H., Roberts, Claire, Suttle, Ben, Yamamoto, Takahiro, Ermakova, Anna O., Dunbar, Fiona, Wiegand, Frank

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Pharmacokinetics and Safety Evaluation of Maribavir in Healthy Japanese and Matched White Participants: A Phase 1, Open‐Label Study von Song, Ivy, Suttle, Ben, Wu, Jingyang, Ilic, Katarina

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Phase 1, placebo-controlled, single ascending dose trial to evaluate the safety, pharmacokinetics and effect on altered states of consciousness of intranasal BPL-003 (5-methoxy-N,N... von Rucker, James Jonathan, Roberts, Claire, Seynaeve, Mathieu, Young, Allan H., Suttle, Ben, Yamamoto, Takahiro, Ermakova, Anna O., Dunbar, Fiona, Wiegand, Frank

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Effect of Censoring Due to Progressive Disease on Tumor Size Kinetic Parameter Estimates von Bonate, Peter L., Suttle, Ben

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Final Report of Phase 1 Study of the DOT1L Inhibitor, Pinometostat (EPZ-5676), in Children with Relapsed or Refractory MLL-r Acute Leukemia von Shukla, Neerav, Wetmore, Cynthia, O'Brien, Maureen M, Silverman, Lewis B., Brown, Patrick, Cooper, Todd M, Thomson, Blythe, Blakemore, Stephen J., Daigle, Scott, Suttle, Ben, Waters, Nigel J., Krivstov, Andrei V, Armstrong, Scott A., Ho, Peter T, Gore, Lia

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Abstract CT328: Exploratory genetic analysis of tumors from a phase I/II dose escalation study of GSK2636771 in patients (pts) with PTEN deficient advanced tumors von de Bono, Johann, Arkenau, Hendrik-Tobias, Mateo, Joaquin, Infante, Jeffrey R., Burris, Howard A., Bang, Yung-Jue, Eder, Joseph, Sharma, Sunil, Chung, Hyun C., Decordova, Shaun, Swales, Karen E., Garrett, Michelle D., Roda-Perez, Desamaparados, Ding, Meichun, Russo, Mark, Yan, Li, Suttle, Ben, Tolson, Jerry M., Halsey, Wendy S., Gopi, Ganji, Van Der Keyl, Harjeet K., Kalyana-Sundaram, Shanker, Sathe, Ganesh M., Motwani, Monica, Kumar, Rakesh

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Phase I and pharmacokinetic (PK) study of pazopanib (P) in combination with two schedules of ifosfamide (I) in patients (pts) with advanced solid tumors (STs) von Hamberg, Paul, Boers-Sonderen, Marye, Loos, Walter J., De Jonge, Maja J., Van Der Graaf, Winette T.A., Suttle, Ben B, Eskens, Ferry, Verweij, Jaap, Van Herpen, Carla, Sleijfer, Stefan

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Abstract A6: Pazopanib combination with paclitaxel and carboplatin in patients with advanced solid tumors and gynecological cancers: Results of two phase I studies von Burris, Howard, du Bois, Andreas, Dowlati, Afshin, Gainer, Shelby, Park, JungWook, Stutts, Melissa, Dar, Mohammed, Suttle, Ben, Mitrica, Ionel, Tan, Antoinette R.

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DRUG INTERACTION STUDY OF GR270773 EMULSION AND PROPOFOL IN HEALTHY VOLUNTEERS: 242-T von Naderer, Odin, Suttle, Ben A, Arumugham, Thangam, Min, Sherene, Jones, Lori S

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DRUG INTERACTION STUDY OF GR270773 EMULSION AND LEVOFLOXACIN (LEVO) IN HEALTHY VOLUNTEERS: 247-T von Naderer, Odin, Suttle, Ben A, Arumugham, Thangam, Min, Sherene S, Jones, Lori S

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SAFETY AND PHARMACOKINETICS OF GR270773, A NOVEL ANTISEPSIS COMPOUND, IN SEPTIC PATIENTS: 618 von Naderer, Odin J, Suttle, Ben, Denning, Jill, Arumugham, Thangam, Min, Sherene, Parkin, Jackie

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Biodiversity and Resilience of Ecosystem Functions von Oliver, Tom H., Heard, Matthew S., Isaac, Nick J.B., Roy, David B., Procter, Deborah, Eigenbrod, Felix, Freckleton, Rob, Hector, Andy, Orme, C. David L., Petchey, Owen L., Proença, Vânia, Raffaelli, David, Suttle, K. Blake, Mace, Georgina M., Martín-López, Berta, Woodcock, Ben A., Bullock, James M.

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The marine viromes of four oceanic regions von Angly, Florent E, Felts, Ben, Breitbart, Mya, Salamon, Peter, Edwards, Robert A, Carlson, Craig, Chan, Amy M, Haynes, Matthew, Kelley, Scott, Liu, Hong, Mahaffy, Joseph M, Mueller, Jennifer E, Nulton, Jim, Olson, Robert, Parsons, Rachel, Rayhawk, Steve, Suttle, Curtis A, Rohwer, Forest

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Minimum Information about an Uncultivated Virus Genome (MIUViG) von Roux, Simon, Adriaenssens, Evelien M, Dutilh, Bas E, Koonin, Eugene V, Kropinski, Andrew M, Krupovic, Mart, Kuhn, Jens H, Lavigne, Rob, Brister, J Rodney, Varsani, Arvind, Amid, Clara, Aziz, Ramy K, Bordenstein, Seth R, Bork, Peer, Breitbart, Mya, Cochrane, Guy R, Daly, Rebecca A, Desnues, Christelle, Duhaime, Melissa B, Emerson, Joanne B, Enault, François, Fuhrman, Jed A, Hingamp, Pascal, Hugenholtz, Philip, Hurwitz, Bonnie L, Ivanova, Natalia N, Labonté, Jessica M, Lee, Kyung-Bum, Malmstrom, Rex R, Martinez-Garcia, Manuel, Mizrachi, Ilene Karsch, Ogata, Hiroyuki, Páez-Espino, David, Petit, Marie-Agnès, Putonti, Catherine, Rattei, Thomas, Reyes, Alejandro, Rodriguez-Valera, Francisco, Rosario, Karyna, Schriml, Lynn, Schulz, Frederik, Steward, Grieg F, Sullivan, Matthew B, Sunagawa, Shinichi, Suttle, Curtis A, Temperton, Ben, Tringe, Susannah G, Thurber, Rebecca Vega, Webster, Nicole S, Whiteson, Katrine L, Wilhelm, Steven W, Wommack, K Eric, Woyke, Tanja, Wrighton, Kelly C, Yilmaz, Pelin, Yoshida, Takashi, Young, Mark J, Yutin, Natalya, Allen, Lisa Zeigler, Kyrpides, Nikos C, Eloe-Fadrosh, Emiley A

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The prokaryotic and eukaryotic microbiome of Pacific oyster spat is shaped by ocean warming but not acidification von Zhong, Kevin Xu, Chan, Amy M, Collicutt, Brenna, Daspe, Maxim, Finke, Jan F, Foss, Megan, Green, Timothy J, Harley, Christopher D G, Hesketh, Amelia V, Miller, Kristina M, Otto, Sarah P, Rolheiser, Kate, Saunders, Rob, Sutherland, Ben J G, Suttle, Curtis A

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Relative genomic impacts of translocation history, hatchery practices, and farm selection in Pacific oyster Crassostrea gigas throughout the Northern Hemisphere von Sutherland, Ben J. G., Rycroft, Claire, Ferchaud, Anne‐Laure, Saunders, Rob, Li, Li, Liu, Sheng, Chan, Amy M., Otto, Sarah P., Suttle, Curtis A., Miller, Kristina M.

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Metatranscriptomics reveals a shift in microbial community composition and function during summer months in a coastal marine environment von Sutherland, Ben J. G., Finke, Jan F., Saunders, Robert, Warne, Snehal, Schulze, Angela D., Strohm, Jeff H. T., Chan, Amy M., Suttle, Curtis A., Miller, Kristina M.

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An amplicon panel for high-throughput and low-cost genotyping of Pacific oyster von Sutherland, Ben J G, Thompson, Neil F, Surry, Liam B, Gujjula, Krishna Reddy, Carrasco, Claudio D, Chadaram, Srinivas, Lunda, Spencer L, Langdon, Christopher J, Chan, Amy M, Suttle, Curtis A, Green, Timothy J

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A Synthesis is Emerging between Biodiversity–Ecosystem Function and Ecological Resilience Research: Reply to Mori von Oliver, Tom H., Heard, Matthew S., Isaac, Nick J.B., Roy, David B., Procter, Deborah, Eigenbrod, Felix, Freckleton, Rob, Hector, Andy, Orme, C. David L., Petchey, Owen L., Proença, Vânia, Raffaelli, David, Blake Suttle, K., Mace, Georgina M., Martín-López, Berta, Woodcock, Ben A., Bullock, James M.

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Relative genomic impacts of translocation history, hatchery practices, and farm selection in Pacific oysterCrassostrea gigasthroughout the Northern Hemisphere von Sutherland, Ben J. G., Rycroft, Claire, Ferchaud, Anne-Laure, Saunders, Rob, Li, Li, Liu, Sheng, Chan, Amy M., Otto, Sarah P., Suttle, Curtis A., Miller, Kristina M.

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