Network-based elucidation of human disease similarities reveals common functional modules enriched for pluripotent drug targets von Suthram, Silpa, Dudley, Joel T, Chiang, Annie P, Chen, Rong, Hastie, Trevor J, Butte, Atul J

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Conserved patterns of protein interaction in multiple species von Sharan, R, Suthram, S, Kelley, R.M, Kuhn, T, McCuine, S, Uetz, P, Sittler, T, Karp, R.M, Ideker, T

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A direct comparison of protein interaction confidence assignment schemes von Suthram, Silpa, Shlomi, Tomer, Ruppin, Eytan, Sharan, Roded, Ideker, Trey

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eQED: an efficient method for interpreting eQTL associations using protein networks von Ideker, Trey, Suthram, Silpa, Beyer, Andreas, Karp, Richard M, Eldar, Yonina

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Evolutionarily conserved herpesviral protein interaction networks von Fossum, Even, Friedel, Caroline C, Rajagopala, Seesandra V, Titz, Björn, Baiker, Armin, Schmidt, Tina, Kraus, Theo, Stellberger, Thorsten, Rutenberg, Christiane, Suthram, Silpa, Bandyopadhyay, Sourav, Rose, Dietlind, von Brunn, Albrecht, Uhlmann, Mareike, Zeretzke, Christine, Dong, Yu-An, Boulet, Hélène, Koegl, Manfred, Bailer, Susanne M, Koszinowski, Ulrich, Ideker, Trey, Uetz, Peter, Zimmer, Ralf, Haas, Jürgen

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Immunogenic arenavirus vector SIV vaccine reduces setpoint viral load in SIV-challenged rhesus monkeys von Boopathy, Archana V., Sharma, Bhawna, Nekkalapudi, Anurag, Wimmer, Raphaela, Gamez-Guerrero, Maria, Suthram, Silpa, Truong, Hoa, Lee, Johnny, Li, Jiani, Martin, Ross, Blair, Wade, Geleziunas, Romas, Orlinger, Klaus, Ahmadi-Erber, Sarah, Lauterbach, Henning, Makadzange, Tariro, Falkard, Brie, Schmidt, Sarah

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Arenavirus-Based Vectors Generate Robust SIV Immunity in Non-Human Primates von Sharma, Bhawna, Bekerman, Elena, Truong, Hoa, Lee, Johnny, Gamez-Guerrero, Maria, Boopathy, Archana, Mital, Rohit, Huang, Katell Bidet, Ahmadi-Erber, Sarah, Wimmer, Raphaela, Schulha, Sophie, Lauterbach, Henning, Orlinger, Klaus, Suthram, Silpa, Lewis, Mark G, Blair, Wade, Makadzange, Tariro, Geleziunas, Romas, Murry, Jeffrey P, Schmidt, Sarah

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Intrahepatic quantification of HBV antigens in chronic hepatitis B reveals heterogeneity and treatment-mediated reductions in HBV core-positive cells von Aggarwal, Abhishek, Odorizzi, Pamela M., Brodbeck, Jens, van Buuren, Nicholas, Moon, Christina, Chang, Silvia, Adona, MaryVic, Suthram, Silpa, Suri, Vithika, Trowe, Torsten, Turner, Scott, Marcellin, Patrick, Buti, Maria, Gaggar, Anuj, Fletcher, Simon P., Diehl, Lauri, Feierbach, Becket, Balsitis, Scott

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Statin use and surface antigen loss in patients with chronic hepatitis B von Iqbal, Shahed, Li, Ruidong, Suthram, Silpa, Wallin, Jeffrey, Trevaskis, James, Hyrina, Anastasia, Fletcher, Simon, Holdorf, Meghan

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Single-cell sequencing of full-length transcripts and T-cell receptors with automated high-throughput Smart-seq3 von Chuang, Hsiu-Chun, Li, Ruidong, Huang, Huang, Liu, Szu-Wen, Wan, Christine, Chaudhuri, Subhra, Yue, Lili, Wong, Terence, Dominical, Venina, Yen, Randy, Ngo, Olivia, Bui, Nam, Stoppler, Hubert, Yi, Tangsheng, Suthram, Silpa, Li, Li, Sun, Kai-Hui

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Early role for IL-6 signalling during generation of induced pluripotent stem cells revealed by heterokaryon RNA-Seq von Brady, Jennifer J., Li, Mavis, Suthram, Silpa, Jiang, Hui, Wong, Wing H., Blau, Helen M.

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Flt3 agonist enhances immunogenicity of arenavirus vector-based simian immunodeficiency virus vaccine in macaques von Boopathy, Archana Vidya, Nekkalapudi, Anurag, Sung, Janette, Schulha, Sophie, Jin, Debi, Sharma, Bhawna, Ng, Sarah, Lu, Sabrina, Wimmer, Raphaela, Suthram, Silpa, Ahmadi-Erber, Sarah, Lauterbach, Henning, Orlinger, Klaus K, Hung, Magdeleine, Carr, Brian, Callebaut, Christian, Geleziunas, Romas, Kuhne, Michelle, Schmidt, Sarah, Falkard, Brie

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The Plasmodium protein network diverges from those of other eukaryotes von Suthram, Silpa, Sittler, Taylor, Ideker, Trey

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Novel, Selective Inhibitors of USP7 Uncover Multiple Mechanisms of Antitumor Activity In Vitro and In Vivo von Ohol, Yamini M., Sun, Michael T., Cutler, Gene, Leger, Paul R., Hu, Dennis X., Biannic, Berenger, Rana, Payal, Cho, Cynthia, Jacobson, Scott, Wong, Steve T., Sanchez, Jerick, Shah, Niket, Pookot, Deepa, Abraham, Betty, Young, Kyle, Suthram, Silpa, Marshall, Lisa A., Bradford, Delia, Kozon, Nathan, Han, Xinping, Okano, Akinori, Maung, Jack, Colas, Christophe, Schwarz, Jacob, Wustrow, David, Brockstedt, Dirk G., Kassner, Paul D.

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Abstract 4752: EBV associated tumors have increased regulatory T cell recruitment and are therefore a potential indication for treatment with potent and selective small molecule CC... von Talay, Oezcan, Jorapur, Aparna, Jacobson, Scott, Marubayashi, Sachie, Marshall, Lisa, Suthram, Silpa, Robles, Omar, Ketcham, John, Reilly, Maureen K., Younai, Ashkaan, Biannic, Berenger, Hu, Dennis, Bui, Minna, Schwarz, Jacob, Kassner, Paul, Cutler, Gene

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Abstract 1104: Targeting the stress response kinase GCN2 to restore immunity in the tumor microenvironment von Ravishankar, Buvana, Adusumilli, Lavanya, Pookot, Deepa Pookot, Huang, Emily, Sreenivasan, Raashi, Marshall, Lisa, Kaveri, Deepika, Talay, Oezcan, Suthram, Silpa, Miakicheva, Svetlana, Okal, Abood, Zibinsky, Mikhail, Jackson, Jeffrey, Shibuya, Grant, Leger, Paul, Tivitmahaisoon, Parcharee, Jacobson, Scott, Wong, Steve, Wadsworth, Angela, Sanchez, Jerick, Brovarney, Martin, Chian, David, Marubayashi, Sachie, Jorapur, Aparna, Bradford, Delia, Colas, Christophe, Cutler, Gene, Schwartz, Jacob, Wustrow, David, Kassner, Paul, Brockstedt, Dirk

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Early role for IL6 signaling in iPS generation revealed by heterokaryon RNA-Seq von Brady, Jennifer J., Li, Mavis, Suthram, Silpa, Jiang, Hui, Wong, Wing H., Blau, Helen M.

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Abstract 2915: Discovery and optimization of potent and selective inhibitors of USP7 to enhance anti-tumor immunity and target tumor growth von Abraham, Betty, Adusumilli, Lavanya, Biannic, Berenger, Bradford, Delia, Brovarney, Martin, Chian, David, Cutler, Gene, Han, Xinping, Hu, Dennis, Jacobson, Scott, Johnson, Sherra, Kassner, Paul, Kaveri, Deepika, Ketcham, John, Kim, Andrea, Leger, Paul, Marshall, Lisa, Marubayashi, Sachie, Maung, Jack, McKinnell, Jenny, Meleza, Cesar, Ohol, Yamini, Okano, Akinori, Peiser, Leanne, Pookot, Deepa, Rana, Payal, Schwarz, Jacob, Shah, Nick, Shibuya, Grant, Sun, Michael, Suthram, Silpa, Talay, Oezcan, Wadsworth, Angela, Wustrow, David, Young, Kyle, Napper, Andrew

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Network-Based Elucidation of Human Disease Similarities Reveals Common Functional Modules Enriched for Pluripotent Drug Targets: e1000662 von Suthram, Silpa, Dudley, Joel T, Chiang, Annie P, Chen, Rong, Hastie, Trevor J, Butte, Atul J

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Evolutionarily Conserved Herpesviral Protein Interaction Networks: e1000570 von Fossum, Even, Friedel, Caroline C, Rajagopala, Seesandra V, Titz, Björn, Baiker, Armin, Schmidt, Tina, Kraus, Theo, Stellberger, Thorsten, Rutenberg, Christiane, Suthram, Silpa, Bandyopadhyay, Sourav, Rose, Dietlind, Brunn, Albrecht von, Uhlmann, Mareike, Zeretzke, Christine, Dong, Yu-An, Boulet, Hélène, Koegl, Manfred, Bailer, Susanne M, Koszinowski, Ulrich, Ideker, Trey, Uetz, Peter, Zimmer, Ralf, Haas, Jürgen

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