A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs von Sutherland, Jeffrey J., Yonchev, Dimitar, Fekete, Alexander, Urban, Laszlo

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"3D, human renal proximal tubule (RPTEC-TERT1) organoids 'tubuloids' for translatable evaluation of nephrotoxins in high-throughput" von Vidal Yucha, Sarah E, Quackenbush, Doug, Chu, Tiffany, Lo, Frederick, Sutherland, Jeffrey J, Kuzu, Guray, Roberts, Christopher, Luna, Fabio, Barnes, S Whitney, Walker, John, Kuss, Pia

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Assessing Concordance of Drug-Induced Transcriptional Response in Rodent Liver and Cultured Hepatocytes von Sutherland, Jeffrey J, Jolly, Robert A, Goldstein, Keith M, Stevens, James L

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A Set of Six Gene Expression Biomarkers Identify Rat Liver Tumorigens in Short-term Assays von Corton, J. Christopher, Hill, Thomas, Sutherland, Jeffrey J., Stevens, James L., Rooney, John

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What general conclusions can we draw from kinase profiling data sets? von Sutherland, Jeffrey J., Gao, Cen, Cahya, Suntara, Vieth, Michal

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Dependence of Molecular Properties on Proteomic Family for Marketed Oral Drugs von Vieth, Michal, Sutherland, Jeffrey J

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Novel Phenotypic Outcomes Identified for a Public Collection of Approved Drugs from a Publicly Accessible Panel of Assays von Lee, Jonathan A, Shinn, Paul, Jaken, Susan, Oliver, Sarah, Willard, Francis S, Heidler, Steven, Peery, Robert B, Oler, Jennifer, Chu, Shaoyou, Southall, Noel, Dexheimer, Thomas S, Smallwood, Jeffrey, Huang, Ruili, Guha, Rajarshi, Jadhav, Ajit, Cox, Karen, Austin, Christopher P, Simeonov, Anton, Sittampalam, G Sitta, Husain, Saba, Franklin, Natalie, Wild, David J, Yang, Jeremy J, Sutherland, Jeffrey J, Thomas, Craig J

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The human hepatocyte TXG-MAPr: gene co-expression network modules to support mechanism-based risk assessment von Callegaro, Giulia, Kunnen, Steven J., Trairatphisan, Panuwat, Grosdidier, Solène, Niemeijer, Marije, den Hollander, Wouter, Guney, Emre, Piñero Gonzalez, Janet, Furlong, Laura, Webster, Yue W., Saez-Rodriguez, Julio, Sutherland, Jeffrey J., Mollon, Jennifer, Stevens, James L., van de Water, Bob

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Lessons in Molecular Recognition. 2. Assessing and Improving Cross-Docking Accuracy von Sutherland, Jeffrey J, Nandigam, Ravi K, Erickson, Jon A, Vieth, Michal

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Relating Molecular Properties and in Vitro Assay Results to in Vivo Drug Disposition and Toxicity Outcomes von Sutherland, Jeffrey J, Raymond, John W, Stevens, James L, Baker, Thomas K, Watson, David E

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Identifying multiscale translational safety biomarkers using a network-based systems approach von Callegaro, Giulia, Schimming, Johannes P., Piñero González, Janet, Kunnen, Steven J., Wijaya, Lukas, Trairatphisan, Panuwat, van den Berk, Linda, Beetsma, Kim, Furlong, Laura I., Sutherland, Jeffrey J., Mollon, Jennifer, Stevens, James L., van de Water, Bob

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A robust high-content imaging approach for probing the mechanism of action and phenotypic outcomes of cell-cycle modulators von Sutherland, Jeffrey J, Low, Jonathan, Blosser, Wayne, Dowless, Michele, Engler, Thomas A, Stancato, Louis F

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"3D, human renal proximal tubule (RPTEC-TERT1) organoids 'tubuloids' for translatable evaluation of nephrotoxins in high-throughput" von Sarah E Vidal Yucha, Doug Quackenbush, Tiffany Chu, Frederick Lo, Jeffrey J Sutherland, Guray Kuzu, Christopher Roberts, Fabio Luna, S Whitney Barnes, John Walker, Pia Kuss

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Managing Psychotropic Medications in Complex, Real-World Patients Using Comprehensive Therapeutic Drug Monitoring von Sutherland, Jeffrey J, Morrison, Ryan D, Daniels, J. Scott, Milne, Stephen B, Ryan, Timothy P

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Medication Exposure in Highly Adherent Psychiatry Patients von Sutherland, Jeffrey J, Daly, Thomas M, Jacobs, Karen, Khawam, Elias A, Pozuelo, Leo, Morrison, Ryan D, Milne, Stephen B, Daniels, J. Scott, Ryan, Timothy P

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Spline-Fitting with a Genetic Algorithm:  A Method for Developing Classification Structure−Activity Relationships von Sutherland, Jeffrey J, O'Brien, Lee A, Weaver, Donald F

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Molecular modeling of the von Willebrand factor A2 Domain and the effects of associated type 2A von Willebrand disease mutations von Sutherland, Jeffrey J, O'Brien, Lee A, Lillicrap, David, Weaver, Donald F

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Founder von Willebrand factor haplotype associated with type 1 von Willebrand disease von O'Brien, Lee A., James, Paula D., Othman, Maha, Berber, Ergul, Cameron, Cherie, Notley, ColleenR.P., Hegadorn, Carol A., Sutherland, Jeffrey J., Hough, Christine, Rivard, Georges E., O'Shaunessey, Denise, Lillicrap, David

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Predicting the Accuracy of Ligand Overlay Methods with Random Forest Models von Nandigam, Ravi K, Evans, David A, Erickson, Jon A, Kim, Sangtae, Sutherland, Jeffrey J

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"3D, human renal proximal tubule von Vidal Yucha, Sarah E, Quackenbush, Doug, Chu, Tiffany, Lo, Frederick, Sutherland, Jeffrey J, Kuzu, Guray, Roberts, Christopher, Luna, Fabio, Barnes, S. Whitney, Walker, John, Kuss, Pia

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