Prognostic Significance of the European LeukemiaNet Standardized System for Reporting Cytogenetic and Molecular Alterations in Adults With Acute Myeloid Leukemia von MROZEK, Krzysztof, MARCUCCI, Guido, PETTENATI, Mark J, HEEREMA, Nyla A, BLOCK, Annemarie W, PATIL, Shivanand R, BAER, Maria R, KOLITZ, Jonathan E, MOORE, Joseph O, CARROLL, Andrew J, STONE, Richard M, LARSON, Richard A, NICOLET, Deedra, BLOOMFIELD, Clara D, MAHARRY, Kati S, BECKER, Heiko, WHITMAN, Susan P, METZELER, Klaus H, SCHWIND, Sebastian, WU, Yue-Zhong, KOHLSCHMIDT, Jessica

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IDH1 and IDH2 Gene Mutations Identify Novel Molecular Subsets Within De Novo Cytogenetically Normal Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study von MARCUCCI, Guido, MAHARRY, Kati, METZELER, Klaus H, POWELL, Bayard L, CARTER, Thomas H, KOLITZ, Jonathan E, WETZLER, Meir, CARROLL, Andrew J, BAER, Maria R, CALIGIURI, Michael A, LARSON, Richard A, BLOOMFIELD, Clara D, WU, Yue-Zhong, RADMACHER, Michael D, MROZEK, Krzysztof, MARGESON, Dean, HOLLAND, Kelsi B, WHITMAN, Susan P, BECKER, Heiko, SCHWIND, Sebastian

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Inhibition of the receptor tyrosine kinase Axl impedes activation of the FLT3 internal tandem duplication in human acute myeloid leukemia: implications for Axl as a potential thera... von Park, Il-Kyoo, Mishra, Anjali, Chandler, Jason, Whitman, Susan P., Marcucci, Guido, Caligiuri, Michael A.

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RUNX1 Mutations Are Associated With Poor Outcome in Younger and Older Patients With Cytogenetically Normal Acute Myeloid Leukemia and With Distinct Gene and MicroRNA Expression Sig... von MENDLER, Jason H, MAHARRY, Kati, NICOLET, Deedra, POWELL, Bayard L, CARTER, Thomas H, WETZLER, Meir, MOORE, Joseph O, KOLITZ, Jonathan E, BAER, Maria R, CARROLL, Andrew J, LARSON, Richard A, CALIGIURI, Michael A, RADMACHER, Michael D, MARCUCCI, Guido, BLOOMFIELD, Clara D, MROZEK, Krzysztof, BECKER, Heiko, METZELER, Klaus H, SCHWIND, Sebastian, WHITMAN, Susan P, KHALIFE, Jihane, KOHLSCHMIDT, Jessica

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TET2 Mutations Improve the New European LeukemiaNet Risk Classification of Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study von METZELER, Klaus H, MAHARRY, Kati, WU, Yue-Zhong, BLUM, William, POWELL, Bayard L, CARTER, Thomas H, WETZLER, Meir, MOORE, Joseph O, KOLITZ, Jonathan E, BAER, Maria R, CARROLL, Andrew J, LARSON, Richard A, RADMACHER, Michael D, CALIGIURI, Michael A, MARCUCCI, Guido, BLOOMFIELD, Clara D, MROZEK, Krzysztof, MARGESON, Dean, BECKER, Heiko, CURFMAN, John, HOLLAND, Kelsi B, SCHWIND, Sebastian, WHITMAN, Susan P

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Age-Related Prognostic Impact of Different Types of DNMT3A Mutations in Adults With Primary Cytogenetically Normal Acute Myeloid Leukemia von MARCUCCI, Guido, METZELER, Klaus H, WU, Yue-Zhong, POWELL, Bayard L, CARTER, Thomas H, KOLITZ, Jonathan E, WETZLER, Meir, CARROLL, Andrew J, BAER, Maria R, MOORE, Joseph O, CALIGIURI, Michael A, LARSON, Richard A, SCHWIND, Sebastian, BLOOMFIELD, Clara D, BECKER, Heiko, MAHARRY, Kati, MROZEK, Krzysztof, RADMACHER, Michael D, KOHLSCHMIDT, Jessica, NICOLET, Deedra, WHITMAN, Susan P

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Epigenetics Meets Genetics in Acute Myeloid Leukemia: Clinical Impact of a Novel Seven-Gene Score von MARCUCCI, Guido, YAN, Pearlly, CURFMAN, John P, WHITMAN, Susan P, EISFELD, Ann-Kathrin, MENDLER, Jason H, SCHWIND, Sebastian, BECKER, Heiko, BÄR, Constance, CARROLL, Andrew J, BAER, Maria R, WETZLER, Meir, MAHARRY, Kati, CARTER, Thomas H, POWELL, Bayard L, KOLITZ, Jonathan E, BYRD, John C, PLASS, Christoph, GARZON, Ramiro, CALIGIURI, Michael A, STONE, Richard M, VOLINIA, Stefano, BUNDSCHUH, Ralf, FRANKHOUSER, David, BLOOMFIELD, Clara D, NICOLET, Deedra, METZELER, Klaus H, KOHLSCHMIDT, Jessica, MRÓZEK, Krzysztof, WU, Yue-Zhong, BUCCI, Donna

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Clinical Role of microRNAs in Cytogenetically Normal Acute Myeloid Leukemia: miR-155 Upregulation Independently Identifies High-Risk Patients von MARCUCCI, Guido, MAHARRY, Kati S, SCHWIND, Sebastian, BECKER, Heiko, EISFELD, Ann-Kathrin, CARROLL, Andrew J, POWELL, Bayard L, KOLITZ, Jonathan E, GARZON, Ramiro, CALIGIURI, Michael A, STONE, Richard M, BLOOMFIELD, Clara D, METZELER, Klaus H, VOLINIA, Stefano, WU, Yue-Zhong, MROZEK, Krzysztof, NICOLET, Deedra, KOHLSCHMIDT, Jessica, WHITMAN, Susan P, MENDLER, Jason H

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An 86-probe-set gene-expression signature predicts survival in cytogenetically normal acute myeloid leukemia von Metzeler, Klaus H., Hummel, Manuela, Bloomfield, Clara D., Spiekermann, Karsten, Braess, Jan, Sauerland, Maria-Cristina, Heinecke, Achim, Radmacher, Michael, Marcucci, Guido, Whitman, Susan P., Maharry, Kati, Paschka, Peter, Larson, Richard A., Berdel, Wolfgang E., Büchner, Thomas, Wörmann, Bernhard, Mansmann, Ulrich, Hiddemann, Wolfgang, Bohlander, Stefan K., Buske, Christian

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Favorable Prognostic Impact of NPM1 Mutations in Older Patients With Cytogenetically Normal De Novo Acute Myeloid Leukemia and Associated Gene- and MicroRNA-Expression Signatures:... von BECKER, Heiko, MARCUCCI, Guido, POWELL, Bayard L, CARTER, Thomas H, KOLITZ, Jonathan E, WETZLER, Meir, CARROLL, Andrew J, BAER, Maria R, CALIGIURI, Michael A, LARSON, Richard A, BLOOMFIELD, Clara D, MAHARRY, Kati, RADMACHER, Michael D, MROZEK, Krzysztof, MARGESON, Dean, WHITMAN, Susan P, WU, Yue-Zhong, SCHWIND, Sebastian, PASCHKA, Peter

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MicroRNA Expression in Cytogenetically Normal Acute Myeloid Leukemia von Marcucci, Guido, Radmacher, Michael D, Maharry, Kati, Mrózek, Krzysztof, Ruppert, Amy S, Paschka, Peter, Vukosavljevic, Tamara, Whitman, Susan P, Baldus, Claudia D, Langer, Christian, Liu, Chang-Gong, Carroll, Andrew J, Powell, Bayard L, Garzon, Ramiro, Croce, Carlo M, Kolitz, Jonathan E, Caligiuri, Michael A, Larson, Richard A, Bloomfield, Clara D

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Prognostic Significance of, and Gene and MicroRNA Expression Signatures Associated With, CEBPA Mutations in Cytogenetically Normal Acute Myeloid Leukemia With High-Risk Molecular F... von MARCUCCI, Guido, MAHARRY, Kati, RUPPERT, Amy S, POWELL, Bayard L, CARROLL, Andrew J, CALIGIURI, Michael A, KOLITZ, Jonathan E, LARSON, Richard A, BLOOMFIELD, Clara D, RADMACHER, Michael D, MROZEK, Krzysztof, VUKOSAVLJEVIC, Tamara, PASCHKA, Peter, WHITMAN, Susan P, LANGER, Christian, BALDUS, Claudia D, LIU, Chang-Gong

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Prognostic Significance of Expression of a Single MicroRNA, miR-181a, in Cytogenetically Normal Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study von SCHWIND, Sebastian, MAHARRY, Kati, PASCHKA, Peter, BALDUS, Claudia D, SHUJUN, Liu, GARZON, Ramiro, POWELL, Bayard L, KOLITZ, Jonathan E, CARROLL, Andrew J, CALIGIURI, Michael A, LARSON, Richard A, MARCUCCI, Guido, RADMACHER, Michael D, BLOOMFIELD, Clara D, MROZEK, Krzysztof, HOLLAND, Kelsi B, MARGESON, Dean, WHITMAN, Susan P, HICKEY, Christopher, BECKER, Heiko, METZELER, Klaus H

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Wilms’ Tumor 1 Gene Mutations Independently Predict Poor Outcome in Adults With Cytogenetically Normal Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study von PASCHKA, Peter, MARCUCCI, Guido, BAER, Maria R, CARROLL, Andrew J, CALIGIURI, Michael A, KOLITZ, Jonathan E, LARSON, Richard A, BLOOMFIELD, Clara D, RUPPERT, Amy S, WHITMAN, Susan P, MROZEK, Krzysztof, MAHARRY, Kati, LANGER, Christian, BALDUS, Claudia D, WEIQIANG ZHAO, POWELL, Bayard L

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Prognostic Importance of MN1 Transcript Levels, and Biologic Insights From MN1-Associated Gene and MicroRNA Expression Signatures in Cytogenetically Normal Acute Myeloid Leukemia:... von LANGER, Christian, MARCUCCI, Guido, POWELL, Bayard L, CARROLL, Andrew J, KOLITZ, Jonathan E, CALIGIURI, Michael A, LARSON, Richard A, BLOOMFIELD, Clara D, HOLLAND, Kelsi B, RADMACHER, Michael D, MAHARRY, Kati, PASCHKA, Peter, WHITMAN, Susan P, MROZEK, Krzysztof, BALDUS, Claudia D, VIJ, Ravi

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High Expression Levels of the ETS-Related Gene, ERG, Predict Adverse Outcome and Improve Molecular Risk-Based Classification of Cytogenetically Normal Acute Myeloid Leukemia: A Can... von MARCUCCI, Guido, MAHARRY, Kati, KOLITZ, Jonathan E, LARSON, Richard A, BLOOMFIELD, Clara D, WHITMAN, Susan P, VUKOSAVLJEVIC, Tamara, PASCHKA, Peter, LANGER, Christian, MROZEK, Krzysztof, BALDUS, Claudia D, CARROLL, Andrew J, POWELL, Bayard L

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Mll partial tandem duplication and Flt3 internal tandem duplication in a double knock-in mouse recapitulates features of counterpart human acute myeloid leukemias von Zorko, Nicholas A., Bernot, Kelsie M., Whitman, Susan P., Siebenaler, Ronald F., Ahmed, Elshafa H., Marcucci, Gabriele G., Yanes, Daniel A., McConnell, Kathleen K., Mao, Charlene, Kalu, Chidimma, Zhang, Xiaoli, Jarjoura, David, Dorrance, Adrienne M., Heerema, Nyla A., Lee, Benjamin H., Huang, Gang, Marcucci, Guido, Caligiuri, Michael A.

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Novel c-CBL and CBL-b ubiquitin ligase mutations in human acute myeloid leukemia von Caligiuri, Michael A., Briesewitz, Roger, Yu, Jianhua, Wang, Lisheng, Wei, Min, Arnoczky, Kristy J., Marburger, Trent B., Wen, Jing, Perrotti, Danilo, Bloomfield, Clara D., Whitman, Susan P.

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Dose Escalation of Lenalidomide in Relapsed or Refractory Acute Leukemias von William Blum, Rebecca B. Klisovic, Heiko Becker, Xiaoxia Yang, Darlene M. Rozewski, Mitch A. Phelps, Ramiro Garzon, Alison Walker, Jason C. Chandler, Susan P. Whitman, John Curfman, Shujun Liu, Larry Schaaf, Jon Mickle, Cheryl Kefauver, Steven M. Devine, Michael R. Grever, Guido Marcucci, and, John C. Byrd

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Overexpression of the ETS-Related Gene, ERG, Predicts a Worse Outcome in Acute Myeloid Leukemia With Normal Karyotype: A Cancer and Leukemia Group B Study von MARCUCCI, Guido, BALDUS, Claudia D, BAER, Maria R, MOORE, Joseph O, PERROTTI, Danilo, CALIGIURI, Michael A, CARROLL, Andrew J, LARSON, Richard A, DE LA CHAPELLE, Albert, BLOOMFIELD, Clara D, RUPPERT, Amy S, RADMACHER, Michael D, MROZEK, Krzysztof, WHITMAN, Susan P, KOLITZ, Jonathan E, EDWARDS, Colin G, VARDIMAN, James W, POWELL, Bayard L

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