Whole-exome sequencing in eccrine porocarcinoma indicates promising therapeutic strategies von Denisova, Evgeniya, Westphal, Dana, Surowy, Harald M., Meier, Friedegund, Hutter, Barbara, Reifenberger, Julia, Rütten, Arno, Schulz, Alexander, Sergon, Mildred, Ziemer, Mirjana, Brors, Benedikt, Betz, Regina C., Redler, Silke

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Predisposition for TMPRSS2-ERG Fusion in Prostate Cancer by Variants in DNA Repair Genes von LUEDEKE, Manuel, LINNERT, Carmen M, HOFER, Matthias D, SUROWY, Harald M, RINCKLEB, Antje E, HOEGEL, Josef, KUEFER, Rainer, RUBIN, Mark A, VOGEL, Walther, MAIER, Christiane

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Gene expression profiling in porocarcinoma indicates heterogeneous tumor development and substantiates poromas as precursor lesions von Holst, Svenja, Weber, Anna K., Meier, Friedegund, Otte, Jörg, Petzsch, Patrick, Reifenberger, Julia, Wachtmeister, Thorsten, Westphal, Dana, Ziemer, Mirjana, Wruck, Wasco, Adjaye, James, Betz, Regina C., Rütten, Arno, Surowy, Harald M., Redler, Silke

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The GPRC5A frameshift variant c.183del is not associated with increased breast cancer risk in BRCA1 mutation carriers von Klaschik, Kristina, Hauke, Jan, Neidhardt, Guido, Tränkle, Christian, Surowy, Harald M., Heilmann‐Heimbach, Stefanie, Rappl, Gunter, Mangold, Elisabeth, Arnold, Norbert, Niederacher, Dieter, Sutter, Christian, Burwinkel, Barbara, Engel, Christoph, Wappenschmidt, Barbara, Meindl, Alfons, Ernst, Corinna, Weber‐Lassalle, Konstantin, Weber‐Lassalle, Nana, Schmidt, Sandra, Borde, Julika, Schmutzler, Rita K., Hahnen, Eric, Pohl‐Rescigno, Esther

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Genexpressionsprofile beim Porokarzinom deuten auf heterogene Tumorentwicklung hin und untermauern Porome als Vorläuferläsionen von Holst, Svenja, Weber, Anna K., Meier, Friedegund, Otte, Jörg, Petzsch, Patrick, Reifenberger, Julia, Wachtmeister, Thorsten, Westphal, Dana, Ziemer, Mirjana, Wruck, Wasco, Adjaye, James, Betz, Regina C., Rütten, Arno, Surowy, Harald M., Redler, Silke

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The prostate cancer risk locus at 10q11 is associated with DNA repair capacity von Rinckleb, Antje E., Surowy, Harald M., Luedeke, Manuel, Varga, Dominic, Schrader, Mark, Hoegel, Josef, Vogel, Walther, Maier, Christiane

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Germline mutations of the MSR1 gene in prostate cancer families from Germany von Maier, Christiane, Vesovic, Zorica, Bachmann, Natascha, Herkommer, Kathleen, Braun, Anja K., Surowy, Harald M., Assum, Guenter, Paiss, Thomas, Vogel, Walther

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Gene expression profiling in porocarcinoma indicates heterogeneous tumor development and substantiates poromas as precursor lesions von Holst, Svenja, Weber, Anna K., Meier, Friedegund, Otte, Jörg, Petzsch, Patrick, Reifenberger, Julia, Wachtmeister, Thorsten, Westphal, Dana, Ziemer, Mirjana, Wruck, Wasco, Adjaye, James, Betz, Regina C., Rütten, Arno, Surowy, Harald M., Redler, Silke

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Genexpressionsprofile beim Porokarzinom deuten auf heterogene Tumorentwicklung hin und untermauern Porome als Vorläuferläsionen von Holst, Svenja, Weber, Anna K., Meier, Friedegund, Otte, Jörg, Petzsch, Patrick, Reifenberger, Julia, Wachtmeister, Thorsten, Westphal, Dana, Ziemer, Mirjana, Wruck, Wasco, Adjaye, James, Betz, Regina C., Rütten, Arno, Surowy, Harald M., Redler, Silke

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Germline mutations of theMSR1 gene in prostate cancer families from Germany von Maier, Christiane, Vesovic, Zorica, Bachmann, Natascha, Herkommer, Kathleen, Braun, Anja K., Surowy, Harald M., Assum, Guenter, Paiss, Thomas, Vogel, Walther

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Exploring the genetics of irritable bowel syndrome: a GWA study in the general population and replication in multinational case-control cohorts von Ek, Weronica E, Reznichenko, Anna, Ripke, Stephan, Niesler, Beate, Zucchelli, Marco, Rivera, Natalia V, Schmidt, Peter T, Pedersen, Nancy L, Magnusson, Patrik, Talley, Nicholas J, Holliday, Elizabeth G, Houghton, Lesley, Gazouli, Maria, Karamanolis, George, Rappold, Gudrun, Burwinkel, Barbara, Surowy, Harald, Rafter, Joseph, Assadi, Ghazaleh, Li, Ling, Papadaki, Evangelia, Gambaccini, Dario, Marchi, Santino, Colucci, Rocchina, Blandizzi, Corrado, Barbaro, Raffaella, Karling, Pontus, Walter, Susanna, Ohlsson, Bodil, Tornblom, Hans, Bresso, Francesca, Andreasson, Anna, Dlugosz, Aldona, Simren, Magnus, Agreus, Lars, Lindberg, Greger, Boeckxstaens, Guy, Bellini, Massimo, Stanghellini, Vincenzo, Barbara, Giovanni, Daly, Mark J, Camilleri, Michael, Wouters, Mira M, D'Amato, Mauro

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Combined genetic and splicing analysis of BRCA1 c.[594-2A>C; 641A>G] highlights the relevance of naturally occurring in-frame transcripts for developing disease gene variant classi... von de la Hoya, Miguel, Soukarieh, Omar, López-Perolio, Irene, Vega, Ana, Walker, Logan C, van Ierland, Yvette, Baralle, Diana, Santamariña, Marta, Lattimore, Vanessa, Wijnen, Juul, Whiley, Philip, Blanco, Ana, Raponi, Michela, Hauke, Jan, Wappenschmidt, Barbara, Becker, Alexandra, Hansen, Thomas V O, Behar, Raquel, Investigators, KConFaB, Niederacher, Diether, Arnold, Norbert, Dworniczak, Bernd, Steinemann, Doris, Faust, Ulrike, Rubinstein, Wendy, Hulick, Peter J, Houdayer, Claude, Caputo, Sandrine M, Castera, Laurent, Pesaran, Tina, Chao, Elizabeth, Brewer, Carole, Southey, Melissa C, van Asperen, Christi J, Singer, Christian F, Sullivan, Jan, Poplawski, Nicola, Mai, Phuong, Peto, Julian, Johnson, Nichola, Burwinkel, Barbara, Surowy, Harald, Bojesen, Stig E, Flyger, Henrik, Lindblom, Annika, Margolin, Sara, Chang-Claude, Jenny, Rudolph, Anja, Radice, Paolo, Galastri, Laura, Olson, Janet E, Hallberg, Emily, Giles, Graham G, Milne, Roger L, Andrulis, Irene L, Glendon, Gord, Hall, Per, Czene, Kamila, Blows, Fiona, Shah, Mitul, Wang, Qin, Dennis, Joe, Michailidou, Kyriaki, McGuffog, Lesley, Bolla, Manjeet K, Antoniou, Antonis C, Easton, Douglas F, Couch, Fergus J, Tavtigian, Sean, Vreeswijk, Maaike P, Parsons, Michael, Meeks, Huong D, Martins, Alexandra, Goldgar, David E, Spurdle, Amanda B

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Age- and Tumor Subtype-Specific Breast Cancer Risk Estimates for CHEK21100delC Carriers von Schmidt, Marjanka K, Hogervorst, Frans, van Hien, Richard, Cornelissen, Sten, Broeks, Annegien, Adank, Muriel A, Meijers, Hanne, Waisfisz, Quinten, Hollestelle, Antoinette, Schutte, Mieke, van den Ouweland, Ans, Hooning, Maartje, Andrulis, Irene L, Anton-Culver, Hoda, Antonenkova, Natalia N, Antoniou, Antonis C, Arndt, Volker, Bermisheva, Marina, Bogdanova, Natalia V, Bolla, Manjeet K, Brauch, Hiltrud, Brenner, Hermann, Brüning, Thomas, Burwinkel, Barbara, Chang-Claude, Jenny, Chenevix-Trench, Georgia, Couch, Fergus J, Cox, Angela, Cross, Simon S, Czene, Kamila, Dunning, Alison M, Fasching, Peter A, Figueroa, Jonine, Fletcher, Olivia, Flyger, Henrik, Galle, Eva, García-Closas, Montserrat, Giles, Graham G, Haeberle, Lothar, Hall, Per, Hillemanns, Peter, Hopper, John L, Jakubowska, Anna, John, Esther M, Jones, Michael, Khusnutdinova, Elza, Knight, Julia A, Kosma, Veli-Matti, Kristensen, Vessela, Lee, Andrew, Lindblom, Annika, Lubinski, Jan, Mannermaa, Arto, Margolin, Sara, Meindl, Alfons, Milne, Roger L, Muranen, Taru A, Newcomb, Polly A, Offit, Kenneth, Park-Simon, Tjoung-Won, Peto, Julian, Pharoah, Paul D P, Robson, Mark, Rudolph, Anja, Sawyer, Elinor J, Schmutzler, Rita K, Seynaeve, Caroline, Soens, Julie, Southey, Melissa C, Spurdle, Amanda B, Surowy, Harald, Swerdlow, Anthony, Tollenaar, Rob A E M, Tomlinson, Ian, Trentham-Dietz, Amy, Vachon, Celine, Wang, Qin, Whittemore, Alice S, Ziogas, Argyrios, van der Kolk, Lizet, Nevanlinna, Heli, Dörk, Thilo, Bojesen, Stig, Easton, Douglas F

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Identification of seven new prostate cancer susceptibility loci through a genome-wide association study von Shahabi, Ahva, John, Esther M, Lose, Felicity, Lange, Ethan M, Farnham, Jim, Chambers, Suzanne, Southey, Melissa C, Lewis, Sarah J, Huddart, Robert A, Donovan, Jenny L, Rebbeck, Timothy R, Corral, Roman, Al Olama, Ali Amin, Thompson, Alan, Woodhouse, Christopher J, Liu, Jo-Fen, Kote-Jarai, Zsofia, Lu, Yong-Jie, FitzGerald, Liesel M, Wilkinson, Rosemary A, Le Marchand, Loic, Karyadi, Danielle M, Guy, Michelle, Cannon-Albright, Lisa, Stefflova, Klara, Cao, Guangwen, Thibodeau, Stephen N, Stanford, Janet L, Schaid, Daniel, Sawyer, Emma J, Koopmeiners, Joseph S, Meyer, Andreas, Zeegers, Maurice, Auvinen, Anssi, Neal, David E, Saunders, Edward J, Kaneva, Radka, Kolonel, Laurence N, Schleutker, Johanna, Cooney, Kathleen A, Vogel, Walther, Dörk, Thilo, Kedda, Mary Anne, Pow-Sang, Julio, Hutter, Pierre, Van As, Nicholas, Serth, Jürgen, Leongamornlert, Daniel A, Edwards, Stephen M, Tammela, Teuvo L, Eeles, Rosalind A, Haiman, Christopher A, Clements, Judith, Severi, Gianluca, Horwich, Alan, Parker, Christopher C, Hopper, John L, Polanowski, Andrea, Zhang, Hong-Wei, Foulkes, William D, Ray, Anna M, Hamdy, Freddie C, Christmas, Tim, Page, Elizabeth C, Park, Jong Y, Maier, Christiane, Cox, Angela, Ardern-Jones, Audrey T, Ogden, Chris, Tymrakiewicz, Malgorzata, Giles, Graham G, English, Dallas R, Patterson, Briony, Spurdle, Amanda, Lophatananon, Artitaya, Khan, Humera, Easton, Douglas F, Ingles, Sue A, Cooper, Colin S, Aitken, Joanne, Slavov, Chavdar, Gardiner, R A (Frank), Dearnaley, David P, Ostrander, Elaine A, Hall, Amanda L, Mitkova, Atanaska, Wahlfors, Tiina, Luedeke, Manuel, Henderson, Brian E, Khoo, Vincent S, Dickinson, Joanne L, Kwon, Erika M, Chappuis, Pierre O, Muir, Kenneth, Sellers, Thomas A, Morrison, Jonathan, McDonnell, Shannon K, O'Brien, Lynne T, Stern, Mariana C, Batra, Jyotsna

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Delineation of the adult phenotype of Coffin–Siris syndrome in 35 individuals von Schmetz, Ariane, Lüdecke, Hermann-Josef, Surowy, Harald, Sivalingam, Sugirtahn, Bruel, Ange-Line, Caumes, Roseline, Charles, Perrine, Chatron, Nicolas, Chrzanowska, Krystyna, Codina-Solà, Marta, Colson, Cindy, Cuscó, Ivon, Denommé-Pichon, Anne-Sophie, Edery, Patrick, Faivre, Laurence, Green, Andrew, Heide, Solveig, Hsieh, Tzung-Chien, Hustinx, Alexander, Kleinendorst, Lotte, Knopp, Cordula, Kraft, Florian, Krawitz, Peter M., Lasa-Aranzasti, Amaia, Lesca, Gaetan, López-González, Vanesa, Maraval, Julien, Mignot, Cyril, Neuhann, Teresa, Netzer, Christian, Oehl-Jaschkowitz, Barbara, Petit, Florence, Philippe, Christophe, Posmyk, Renata, Putoux, Audrey, Reis, André, Sánchez-Soler, María José, Suh, Julia, Tkemaladze, Tinatin, Tran Mau Them, Frédéric, Travessa, André, Trujillano, Laura, Valenzuela, Irene, van Haelst, Mieke M., Vasileiou, Georgia, Vincent-Delorme, Catherine, Walther, Mona, Verde, Pablo, Bramswig, Nuria C., Wieczorek, Dagmar

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No evidence that protein truncating variants in BRIP1 are associated with breast cancer risk: implications for gene panel testing von Easton, Douglas F, Lesueur, Fabienne, Decker, Brennan, Li, Jun, Allen, Jamie, Luccarini, Craig, Pooley, Karen A, Shah, Mitul, Dennis, Joe, Ahmad, Jamil, Thompson, Ella R, Pertesi, Maroulio, Voegele, Catherine, Mebirouk, Noura, Durand, Geoffroy, Forey, Nathalie, Luben, Robert N, Ahmed, Shahana, Baynes, Caroline, Beckman, Matthias W, Benitez, Javier, Van Den Berg, David, Blot, William J, Bogdanova, Natalia V, Bojesen, Stig E, Brenner, Hermann, Chang-Claude, Jenny, Chia, Kee Seng, Choi, Ji-Yeob, Conroy, Don M, Cox, Angela, Cross, Simon S, Czene, Kamila, Darabi, Hatef, Devilee, Peter, Eriksson, Mikael, Fasching, Peter A, Figueroa, Jonine, Flyger, Henrik, García-Closas, Montserrat, Giles, Graham G, González-Neira, Anna, Haiman, Christopher A, Hall, Per, Hart, Steven N, Hartman, Mikael, Hooning, Maartje J, Ito, Hidemi, Jakubowska, Anna, James, Paul A, John, Esther M, Johnson, Nichola, Kang, Daehee, Kosma, Veli-Matti, Kristensen, Vessela, Lambrechts, Diether, Lindblom, Annika, Long, Jirong, Lophatananon, Artitaya, Lubinski, Jan, Manoukian, Siranoush, Margolin, Sara, Matsuo, Keitaro, Mitchell, Gillian, Muir, Kenneth, Nevelsteen, Ines, Peterlongo, Paolo, Pylkäs, Katri, Schmutzler, Rita K, Shen, Chen-Yang, Shu, Xiao-Ou, Southey, Melissa C, Swerdlow, Anthony, Teo, Soo H, Tomlinson, Ian, Torres, Diana, Vachon, Celine, Verhoef, Senno, Zheng, Wei, Zheng, Ying, Nevanlinna, Heli, Scott, Rodney J, Hopper, John L, Couch, Fergus J, Winqvist, Robert, Burwinkel, Barbara, Sawyer, Elinor J, Schmidt, Marjanka K, Rudolph, Anja, Dörk, Thilo, Brauch, Hiltrud, Hamann, Ute, Milne, Roger L, Fletcher, Olivia, Pharoah, Paul D P, Campbell, Ian G, Le Calvez-Kelm, Florence, Goldgar, David E, Tavtigian, Sean V, Chenevix-Trench, Georgia

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Heritability of baseline and induced micronucleus frequencies von Surowy, Harald, Rinckleb, Antje, Luedeke, Manuel, Stuber, Madeleine, Wecker, Anna, Varga, Dominic, Maier, Christiane, Hoegel, Josef, Vogel, Walther

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FANCM c.5791C>T nonsense mutation (rs144567652) induces exon skipping, affects DNA repair activity and is a familial breast cancer risk factor von Peterlongo, Paolo, Catucci, Irene, Colombo, Mara, Caleca, Laura, Mucaki, Eliseos, Bogliolo, Massimo, Marin, Maria, Damiola, Francesca, Bernard, Loris, Pensotti, Valeria, Volorio, Sara, Dall'Olio, Valentina, Meindl, Alfons, Bartram, Claus, Sutter, Christian, Surowy, Harald, Sornin, Valérie, Dondon, Marie-Gabrielle, Eon-Marchais, Séverine, Stoppa-Lyonnet, Dominique, Andrieu, Nadine, Sinilnikova, Olga M, Mitchell, Gillian, James, Paul A, Thompson, Ella, Marchetti, Marina, Verzeroli, Cristina, Tartari, Carmen, Capone, Gabriele Lorenzo, Putignano, Anna Laura, Genuardi, Maurizio, Medici, Veronica, Marchi, Isabella, Federico, Massimo, Tognazzo, Silvia, Matricardi, Laura, Agata, Simona, Dolcetti, Riccardo, Della Puppa, Lara, Cini, Giulia, Gismondi, Viviana, Viassolo, Valeria, Perfumo, Chiara, Mencarelli, Maria Antonietta, Baldassarri, Margherita, Peissel, Bernard, Roversi, Gaia, Silvestri, Valentina, Rizzolo, Piera, Spina, Francesca, Vivanet, Caterina, Tibiletti, Maria Grazia, Caligo, Maria Adelaide, Gambino, Gaetana, Tommasi, Stefania, Pilato, Brunella, Tondini, Carlo, Corna, Chiara, Bonanni, Bernardo, Barile, Monica, Osorio, Ana, Benitez, Javier, Balestrino, Luisa, Ottini, Laura, Manoukian, Siranoush, Pierotti, Marco A, Renieri, Alessandra, Varesco, Liliana, Couch, Fergus J, Wang, Xianshu, Devilee, Peter, Hilbers, Florentine S, van Asperen, Christi J, Viel, Alessandra, Montagna, Marco, Cortesi, Laura, Diez, Orland, Balmaña, Judith, Hauke, Jan, Schmutzler, Rita K, Papi, Laura, Pujana, Miguel Angel, Lázaro, Conxi, Falanga, Anna, Offit, Kenneth, Vijai, Joseph, Campbell, Ian, Burwinkel, Barbara, Kvist, Anders, Ehrencrona, Hans, Mazoyer, Sylvie, Pizzamiglio, Sara, Verderio, Paolo, Surralles, Jordi, Rogan, Peter K, Radice, Paolo

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Physical activity, sedentary time and breast cancer risk: a Mendelian randomisation study von Martin, Richard M, Giles, Graham G, Michailidou, Kyriaki, Wang, Qin, Investigators, Abctb, Ahearn, Thomas U, Ambrosone, Christine B, Andrulis, Irene L, Arndt, Volker, Aronson, Kristan J, Augustinsson, Annelie, Auvinen, Päivi, Beane Freeman, Laura E, Becher, Heiko, Beckmann, Matthias W, Bermisheva, Marina, Bogdanova, Natalia V, Bojesen, Stig E, Bonanni, Bernardo, Brüning, Thomas, Camp, Nicola J, Canzian, Federico, Castelao, Jose E, Cessna, Melissa H, Chang-Claude, Jenny, Chanock, Stephen J, Clarke, Christine L, Conroy, Don M, Couch, Fergus J, Czene, Kamila, Daly, Mary B, Dörk, Thilo, Dwek, Miriam, Eccles, Diana M, Eliassen, A Heather, Fasching, Peter A, Gabrielson, Marike, Gago-Dominguez, Manuela, García-Sáenz, José A, Goldberg, Mark S, Häberle, Lothar, Hall, Per, Hamann, Ute, Hart, Steven N, Hollestelle, Antoinette, Hooning, Maartje J, Hopper, John, Howell, Anthony, Hunter, David J, Jakubowska, Anna, John, Esther M, Jung, Audrey, Keeman, Renske, Kitahara, Cari M, Koutros, Stella, Kristensen, Vessela N, Kubelka-Sabit, Katerina, Kurian, Allison W, Lacey, James V, Le Marchand, Loic, Loibl, Sibylle, Lubiński, Jan, Mannermaa, Arto, Margolin, Sara, Mulligan, Anna Marie, Murphy, Rachel A, Collaborators, Nbcs, Nevanlinna, Heli, Peto, Julian, Plaseska-Karanfilska, Dijana, Rack, Brigitte, Radice, Paolo, Rees-Punia, Erika, Rennert, Hedy S, Romero, Atocha, Saloustros, Emmanouil, Schmidt, Marjanka K, Schwentner, Lukas, Scott, Christopher, Shah, Mitul, Shu, Xiao-Ou, Simard, Jacques, Southey, Melissa C, Stone, Jennifer, Surowy, Harald, Swerdlow, Anthony J, Tamimi, Rulla M, Taylor, Jack A, Terry, Mary Beth, Truong, Thérèse, Untch, Michael, Joseph, Vijai, Weinberg, Clarice R, Wolk, Alicja, Zheng, Wei, Dunning, Alison M, Pharoah, Paul DP, Easton, Douglas F, Lynch, Brigid M, Breast Cancer Association Consortium

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Functional annotation of the 2q35 breast cancer risk locus implicates a structural variant in influencing activity of a long-range enhancer element von Baxter, Joseph S, Johnson, Nichola, Gillespie, Andrea, Brough, Rachel, Bolla, Manjeet K, Dennis, Joe, Ahearn, Thomas U, Anton-Culver, Hoda, Antonenkova, Natalia N, Arndt, Volker, Bojesen, Stig E, Brenner, Hermann, Cai, Qiuyin, Canzian, Federico, Castelao, Jose E, Chan, Tsun L, Chang-Claude, Jenny, Chanock, Stephen J, Chenevix-Trench, Georgia, Choi, Ji-Yeob, NBCS Collaborators, Colonna, Sarah, Couch, Fergus J, Cox, Angela, Cross, Simon S, Czene, Kamila, Daly, Mary B, Devilee, Peter, Dossus, Laure, Dwek, Miriam, Eliassen, A Heather, Engel, Christoph, Flyger, Henrik, Gago-Dominguez, Manuela, Gao, Chi, García-Closas, Montserrat, García-Sáenz, José A, Goldberg, Mark S, Guénel, Pascal, Gündert, Melanie, Haeberle, Lothar, Hall, Per, Hartman, Mikael, Hauke, Jan, Hollestelle, Antoinette, Hoppe, Reiner, Hopper, John L, Hou, Ming-Feng, ABCTB Investigators, Iwasaki, Motoki, Jager, Agnes, Jakubowska, Anna, Joseph, Vijai, Jung, Audrey, Kaaks, Rudolf, Keeman, Renske, Kim, Sung-Won, Kraft, Peter, Kristensen, Vessela N, Kwong, Ava, Lacey, James V, Larsson, Susanna C, Lophatananon, Artitaya, Manoukian, Siranoush, Matsuo, Keitaro, Mayes, Rebecca, Menon, Usha, O'Brien, Katie M, Park, Sue K, Park-Simon, Tjoung-Won, Patel, Alpa V, Peto, Julian, Plaseska-Karanfilska, Dijana, Presneau, Nadege, Rack, Brigitte, Rennert, Gad, Ruebner, Matthias, Saloustros, Emmanouil, Sandler, Dale P, Sawyer, Elinor J, Shen, Chen-Yang, Southey, Melissa C, Surowy, Harald, Swerdlow, Anthony J, Tamimi, Rulla M, Taylor, Jack A, Terry, Mary Beth, Tomlinson, Ian, Tseng, Chiu-Chen, Vachon, Celine M, van den Ouweland, Ans MW, Wendt, Camilla, Winham, Stacey J, Winqvist, Robert, Yamaji, Taiki, Zheng, Wei, Ziogas, Argyrios, Dunning, Alison M, Lord, Christopher J, Fletcher, Olivia

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