Heritability of serum TSH, free T4 and free T3 concentrations: a study of a large UK twin cohort von Panicker, V., Wilson, S. G., Spector, T. D., Brown, S. J., Falchi, M., Richards, J. B., Surdulescu, G. L., Lim, E. M., Fletcher, S. J., Walsh, J. P.

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The effects of social status on biological aging as measured by white‐blood‐cell telomere length von Cherkas, L. F., Aviv, A., Valdes, A. M., Hunkin, J. L., Gardner, J. P., Surdulescu, G. L., Kimura, M., Spector, T. D.

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Mapping Genetic Loci That Determine Leukocyte Telomere Length in a Large Sample of Unselected Female Sibling Pairs von Andrew, Toby, Aviv, Abraham, Falchi, Mario, Surdulescu, Gabriela L., Gardner, Jeffrey P., Lu, Xiaobin, Kimura, Masayuki, Kato, Bernet S., Valdes, Ana M., Spector, Tim D.

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Quantitative genetics of circulating Dickkopf-related protein 1 (DKK1) in community-based sample of UK twins von Prakash, J., Williams, F. M. K., Trofimov, S., Surdulescu, G., Spector, T., Livshits, G.

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Migraine and Antiphospholipid Antibodies: No Association Found in Migraine-Discordant Monozygotic Twins von Williams, FMK, Cherkas, LF, Bertolaccini, ML, Murru, V, Surdulescu, GL, Hughes, GRV, Khamashta, MA, Spector, TD, MacGregor, AJ

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Higher serum vitamin D concentrations are associated with longer leukocyte telomere length in women von Richards, J. Brent, Valdes, Ana M, Gardner, Jeffrey P, Paximadas, Dimitri, Kimura, Masayuki, Nessa, Ayrun, Lu, Xiaobin, Surdulescu, Gabriela L, Swaminathan, Rami, Spector, Tim D, Aviv, Abraham

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17 GENOME-WIDE ASSOCIATION SCAN OF OSTEOARTHRITIS OF THE KNEE von Valdes, A.M, Timms, K, Mitchell, E, Nessa, A, Hart, D, Surdulescu, G, Gutin, A, Abkevich, V, Doherty, M, Lanchbury, J.S, Spector, T.D

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Common Sequence Variation in FLNB Regulates Bone Structure in Women in the General Population and FLNB mRNA Expression in Osteoblasts In Vitro von Wilson, Scott G, Jones, Michelle R, Mullin, Ben H, Dick, Ian M, Richards, J Brent, Pastinen, Tomi M, Grundberg, Elin, Ljunggren, Östen, Surdulescu, Gabriela L, Dudbridge, Frank, Elliott, Katherine S, Cervino, Alessandra CL, Spector, Timothy D, Prince, Richard L

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Oral Abstracts 7: RA Clinical O37. Long-Term Outcomes of Early RA Patients Initiated with Adalimumab Plus Methotrexate Compared with Methotrexate Alone Following a Targeted Treatme... von Fleischmann, R., van Vollenhoven, R. F., Smolen, J., Emery, P., Florentinus, S., Rathmann, S., Kupper, H., Kavanaugh, A., Taylor, P., Genovese, M., Keystone, E. C., Drescher, E., Berclaz, P.-Y., Lee, C., Fidelus-Gort, R., Schlichting, D., Beattie, S., Luchi, M., Macias, W., Dikranian, A. H., Alten, R., Klearman, M., Musselman, D., Agarwal, S., Green, J., Gabay, C., Weinblatt, M. E., Schiff, M. H., Valente, R., van der Heijde, D., Citera, G., Zhao, C., Maldonado, M. A., Rakieh, C., Nam, J. L., Hunt, L., Villeneuve, E., Bissell, L.-A., Das, S., Conaghan, P., McGonagle, D., Wakefield, R. J., Wright, H. L., Thomas, H. B., Moots, R., Edwards, S. W., Hamann, P., Heward, J., McHugh, N., Lindsay, M. A., Haroon, M., Giles, J. T., Winchester, R., FitzGerald, O., Karaderi, T., Cohen, C. J., Keidel, S., Appleton, L. H., Macfarlane, G. J., Siebert, S., Evans, D., Paul Wordsworth, B., Plant, D., Bowes, J., Orozco, G., Morgan, A. W., Wilson, A. G., Isaacs, J., Barton, A., Williams, F. M., Livshits, G., Spector, T., MacGregor, A., Scollen, S., Cao, D., Memari, Y., Hyde, C. L., Zhang, B., Sidders, B., Ziemek, D., Shi, Y., Harris, J., Harrow, I., Dougherty, B., Malarstig, A., McEwen, R., Stephens, J. L., Patel, K., Shin, S.-Y., Surdulescu, G., He, W., Jin, X., McMahon, S. B., Soranzo, N., John, S., Wang, J., Spector, T. D., Baker, J., Litherland, G. J., Rowan, A. D.

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Linkage and potential association of obesity-related phenotypes with two genes on chromosome 12q24 in a female dizygous twin cohort von Wilson, Scott G, Adam, Gail, Langdown, Maria, Reneland, Rikard, Braun, Andreas, Andrew, Toby, Surdulescu, Gabriela L, Norberg, Maria, Dudbridge, Frank, Reed, Peter W, Sambrook, Philip N, Kleyn, Patrick W, Spector, Tim D

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Identification and Functional Characterization of G6PC2 Coding Variants Influencing Glycemic Traits Define an Effector Transcript at the G6PC2-ABCB11 Locus von Mahajan, A, Sim, X, Ng, HJ, Manning, A, Rivas, MA, Highland, HM, Locke, AE, Grarup, N, Im, HK, Cingolani, P, Flannick, J, Fontanillas, P, Fuchsberger, C, Gaulton, KJ, Teslovich, TM, Rayner, NW, Robertson, NR, Beer, NL, Rundle, JK, Bork-Jensen, J, Ladenvall, C, Blancher, C, Buck, D, Buck, G, Burtt, NP, Gabriel, S, Gjesing, AP, Groves, CJ, Hollensted, M, Huyghe, JR, Jackson, AU, Jun, G, Justesen, JM, Mangino, M, Murphy, J, Neville, M, Onofrio, R, Small, KS, Stringham, HM, Syvanen, A-C, Trakalo, J, Abecasis, G, Bell, GI, Blangero, J, Cox, NJ, Duggirala, R, Hanis, CL, Seielstad, M, Wilson, JG, Christensen, C, Brandslund, I, Rauramaa, R, Surdulescu, GL, Doney, ASF, Lannfelt, L, Linneberg, A, Isomaa, B, Tuomi, T, Jorgensen, ME, Jorgensen, T, Kuusisto, J, Uusitupa, M, Salomaa, V, Spector, TD, Morris, AD, Palmer, CNA, Collins, FS, Mohlke, KL, Bergman, RN, Ingelsson, E, Lind, L, Tuomilehto, J, Hansen, T, Watanabe, RM, Prokopenko, I, Dupuis, J, Karpe, F, Groop, L, Laakso, M, Pedersen, O, Florez, JC, Morris, AP, Altshuler, D, Meigs, JB, Boehnke, M, McCarthy, MI, Lindgren, CM, Gloyn, AL

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Identification of QTLs for serum lipid levels in a female sib-pair cohort: a novel application to improve the power of two-locus linkage analysis von Falchi, Mario, Andrew, Toby, Snieder, Harold, Swaminathan, Ramasamyiyer, Surdulescu, Gabriela L., Spector, Tim D.

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Association study of candidate genes for the prevalence and progression of knee osteoarthritis von Valdes, Ana M., Hart, Deborah J., Jones, Karen A., Surdulescu, Gabriela, Swarbrick, Peter, Doyle, David V., Schafer, Alan J., Spector, Tim D.

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Reproducible genetic associations between candidate genes and clinical knee osteoarthritis in men and women von Valdes, Ana M., Van Oene, Mark, Hart, Deborah J., Surdulescu, Gabriela L., Loughlin, John, Doherty, Michael, Spector, Tim D.

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Genome-wide association study with 1000 genomes imputation identifies signals for nine sex hormone-related phenotypes von Ruth, Katherine S, Campbell, Purdey J, Chew, Shelby, Lim, Ee Mun, Hadlow, Narelle, Stuckey, Bronwyn G A, Brown, Suzanne J, Feenstra, Bjarke, Joseph, John, Surdulescu, Gabriela L, Zheng, Hou Feng, Richards, J Brent, Murray, Anna, Spector, Tim D, Wilson, Scott G, Perry, John R B

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Upper-Airway Stimulation for Obstructive Sleep Apnea von Strollo, Patrick J, Soose, Ryan J, Maurer, Joachim T, de Vries, Nico, Cornelius, Jason, Froymovich, Oleg, Hanson, Ronald D, Padhya, Tapan A, Steward, David L, Gillespie, M. Boyd, Woodson, B. Tucker, Van de Heyning, Paul H, Goetting, Mark G, Vanderveken, Oliver M, Feldman, Neil, Knaack, Lennart, Strohl, Kingman P

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Genome-wide association study using family-based cohorts identifies the WLS and CCDC170/ESR1 loci as associated with bone mineral density von Mullin, Benjamin H, Walsh, John P, Zheng, Hou-Feng, Brown, Suzanne J, Surdulescu, Gabriela L, Curtis, Charles, Breen, Gerome, Dudbridge, Frank, Richards, J Brent, Spector, Tim D, Wilson, Scott G

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Genetic variation influencing DNA methylation provides insights into molecular mechanisms regulating genomic function von Hawe, Johann S., Wilson, Rory, Schmid, Katharina T., Zhou, Li, Lakshmanan, Lakshmi Narayanan, Lehne, Benjamin C., Kühnel, Brigitte, Scott, William R., Wielscher, Matthias, Yew, Yik Weng, Baumbach, Clemens, Lee, Dominic P., Marouli, Eirini, Bernard, Manon, Pfeiffer, Liliane, Matías-García, Pamela R., Autio, Matias I., Bourgeois, Stephane, Herder, Christian, Karhunen, Ville, Meitinger, Thomas, Prokisch, Holger, Rathmann, Wolfgang, Roden, Michael, Sebert, Sylvain, Shin, Jean, Strauch, Konstantin, Zhang, Weihua, Tan, Wilson L. W., Hauck, Stefanie M., Merl-Pham, Juliane, Grallert, Harald, Barbosa, Eudes G. V., Illig, Thomas, Peters, Annette, Paus, Tomas, Pausova, Zdenka, Deloukas, Panos, Foo, Roger S. Y., Jarvelin, Marjo-Riitta, Kooner, Jaspal S., Loh, Marie, Heinig, Matthias, Gieger, Christian, Waldenberger, Melanie, Chambers, John C.

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Identification of novel genetic Loci associated with thyroid peroxidase antibodies and clinical thyroid disease von Medici, Marco, Porcu, Eleonora, Pistis, Giorgio, Teumer, Alexander, Brown, Suzanne J, Jensen, Richard A, Rawal, Rajesh, Roef, Greet L, Plantinga, Theo S, Vermeulen, Sita H, Lahti, Jari, Simmonds, Matthew J, Husemoen, Lise Lotte N, Freathy, Rachel M, Shields, Beverley M, Pietzner, Diana, Nagy, Rebecca, Broer, Linda, Chaker, Layal, Korevaar, Tim I M, Plia, Maria Grazia, Sala, Cinzia, Völker, Uwe, Richards, J Brent, Sweep, Fred C, Gieger, Christian, Corre, Tanguy, Kajantie, Eero, Thuesen, Betina, Taes, Youri E, Visser, W Edward, Hattersley, Andrew T, Kratzsch, Jürgen, Hamilton, Alexander, Li, Wei, Homuth, Georg, Lobina, Monia, Mariotti, Stefano, Soranzo, Nicole, Cocca, Massimiliano, Nauck, Matthias, Spielhagen, Christin, Ross, Alec, Arnold, Alice, van de Bunt, Martijn, Liyanarachchi, Sandya, Heier, Margit, Grabe, Hans Jörgen, Masciullo, Corrado, Galesloot, Tessel E, Lim, Ee M, Reischl, Eva, Leedman, Peter J, Lai, Sandra, Delitala, Alessandro, Bremner, Alexandra P, Philips, David I W, Beilby, John P, Mulas, Antonella, Vocale, Matteo, Abecasis, Goncalo, Forsen, Tom, James, Alan, Widen, Elisabeth, Hui, Jennie, Prokisch, Holger, Rietzschel, Ernst E, Palotie, Aarno, Feddema, Peter, Fletcher, Stephen J, Schramm, Katharina, Rotter, Jerome I, Kluttig, Alexander, Radke, Dörte, Traglia, Michela, Surdulescu, Gabriela L, He, Huiling, Franklyn, Jayne A, Tiller, Daniel, Vaidya, Bijay, de Meyer, Tim, Jørgensen, Torben, Eriksson, Johan G, O'Leary, Peter C, Wichmann, Eric, Hermus, Ad R, Psaty, Bruce M, Ittermann, Till, Hofman, Albert, Bosi, Emanuele, Schlessinger, David, Wallaschofski, Henri, Pirastu, Nicola, Aulchenko, Yurii S, de la Chapelle, Albert, Netea-Maier, Romana T, Gough, Stephen C L, Meyer Zu Schwabedissen, Henriette, Frayling, Timothy M, Kaufman, Jean-Marc

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A Locus on Chromosome 1p36 Is Associated with Thyrotropin and Thyroid Function as Identified by Genome-wide Association Study von Panicker, Vijay, Wilson, Scott G., Walsh, John P., Richards, J. Brent, Brown, Suzanne J., Beilby, John P., Bremner, Alexandra P., Surdulescu, Gabriela L., Qweitin, Emad, Gillham-Nasenya, Irina, Soranzo, Nicole, Lim, Ee M., Fletcher, Stephen J., Spector, Tim D.

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