Antibiotic resistance is ancient von D’Costa, Vanessa M., King, Christine E., Kalan, Lindsay, Morar, Mariya, Sung, Wilson W. L., Schwarz, Carsten, Froese, Duane, Zazula, Grant, Calmels, Fabrice, Debruyne, Regis, Golding, G. Brian, Poinar, Hendrik N., Wright, Gerard D.

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The Personal Genome Project Canada: findings from whole genome sequences of the inaugural 56 participants von Reuter, Miriam S, Walker, Susan, Thiruvahindrapuram, Bhooma, Whitney, Joe, Cohn, Iris, Sondheimer, Neal, Yuen, Ryan K C, Trost, Brett, Paton, Tara A, Pereira, Sergio L, Herbrick, Jo-Anne, Wintle, Richard F, Merico, Daniele, Howe, Jennifer, MacDonald, Jeffrey R, Lu, Chao, Nalpathamkalam, Thomas, Sung, Wilson W L, Wang, Zhuozhi, Patel, Rohan V, Pellecchia, Giovanna, Wei, John, Strug, Lisa J, Bell, Sherilyn, Kellam, Barbara, Mahtani, Melanie M, Bassett, Anne S, Bombard, Yvonne, Weksberg, Rosanna, Shuman, Cheryl, Cohn, Ronald D, Stavropoulos, Dimitri J, Bowdin, Sarah, Hildebrandt, Matthew R, Wei, Wei, Romm, Asli, Pasceri, Peter, Ellis, James, Ray, Peter, Meyn, M Stephen, Monfared, Nasim, Hosseini, S Mohsen, Joseph-George, Ann M, Keeley, Fred W, Cook, Ryan A, Fiume, Marc, Lee, Hin C, Marshall, Christian R, Davies, Jill, Hazell, Allison, Buchanan, Janet A, Szego, Michael J, Scherer, Stephen W

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High-quality read-based phasing of cystic fibrosis cohort informs genetic understanding of disease modification von Mastromatteo, Scott, Chen, Angela, Gong, Jiafen, Lin, Fan, Thiruvahindrapuram, Bhooma, Sung, Wilson W.L., Whitney, Joe, Wang, Zhuozhi, Patel, Rohan V., Keenan, Katherine, Halevy, Anat, Panjwani, Naim, Avolio, Julie, Wang, Cheng, Côté-Maurais, Guillaume, Bégin, Stéphanie, Adam, Damien, Brochiero, Emmanuelle, Bjornson, Candice, Chilvers, Mark, Price, April, Parkins, Michael, van Wylick, Richard, Mateos-Corral, Dimas, Hughes, Daniel, Smith, Mary Jane, Morrison, Nancy, Tullis, Elizabeth, Stephenson, Anne L., Wilcox, Pearce, Quon, Bradley S., Leung, Winnie M., Solomon, Melinda, Sun, Lei, Ratjen, Felix, Strug, Lisa J.

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Molecular Diagnostic Yield of Chromosomal Microarray Analysis and Whole-Exome Sequencing in Children With Autism Spectrum Disorder von Tammimies, Kristiina, Marshall, Christian R, Walker, Susan, Kaur, Gaganjot, Thiruvahindrapuram, Bhooma, Lionel, Anath C, Yuen, Ryan K. C, Uddin, Mohammed, Roberts, Wendy, Weksberg, Rosanna, Woodbury-Smith, Marc, Zwaigenbaum, Lonnie, Anagnostou, Evdokia, Wang, Zhuozhi, Wei, John, Howe, Jennifer L, Gazzellone, Matthew J, Lau, Lynette, Sung, Wilson W. L, Whitten, Kathy, Vardy, Cathy, Crosbie, Victoria, Tsang, Brian, D’Abate, Lia, Tong, Winnie W. L, Luscombe, Sandra, Doyle, Tyna, Carter, Melissa T, Szatmari, Peter, Stuckless, Susan, Merico, Daniele, Stavropoulos, Dimitri J, Scherer, Stephen W, Fernandez, Bridget A

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Whole genome sequencing resource identifies 18 new candidate genes for autism spectrum disorder von C Yuen, Ryan K, Merico, Daniele, Bookman, Matt, L Howe, Jennifer, Thiruvahindrapuram, Bhooma, Patel, Rohan V, Whitney, Joe, Deflaux, Nicole, Bingham, Jonathan, Wang, Zhuozhi, Pellecchia, Giovanna, Buchanan, Janet A, Walker, Susan, Marshall, Christian R, Uddin, Mohammed, Zarrei, Mehdi, Deneault, Eric, D'Abate, Lia, Chan, Ada J S, Koyanagi, Stephanie, Paton, Tara, Pereira, Sergio L, Hoang, Ny, Engchuan, Worrawat, Higginbotham, Edward J, Ho, Karen, Lamoureux, Sylvia, Li, Weili, MacDonald, Jeffrey R, Nalpathamkalam, Thomas, Sung, Wilson W L, Tsoi, Fiona J, Wei, John, Xu, Lizhen, Tasse, Anne-Marie, Kirby, Emily, Van Etten, William, Twigger, Simon, Roberts, Wendy, Drmic, Irene, Jilderda, Sanne, Modi, Bonnie MacKinnon, Kellam, Barbara, Szego, Michael, Cytrynbaum, Cheryl, Weksberg, Rosanna, Zwaigenbaum, Lonnie, Woodbury-Smith, Marc, Brian, Jessica, Senman, Lili, Iaboni, Alana, Doyle-Thomas, Krissy, Thompson, Ann, Chrysler, Christina, Leef, Jonathan, Savion-Lemieux, Tal, Smith, Isabel M, Liu, Xudong, Nicolson, Rob, Seifer, Vicki, Fedele, Angie, Cook, Edwin H, Dager, Stephen, Estes, Annette, Gallagher, Louise, Malow, Beth A, Parr, Jeremy R, Spence, Sarah J, Vorstman, Jacob, Frey, Brendan J, Robinson, James T, Strug, Lisa J, Fernandez, Bridget A, Elsabbagh, Mayada, Carter, Melissa T, Hallmayer, Joachim, Knoppers, Bartha M, Anagnostou, Evdokia, Szatmari, Peter, Ring, Robert H, Glazer, David, Pletcher, Mathew T, Scherer, Stephen W

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A Comprehensive Workflow for Read Depth-Based Identification of Copy-Number Variation from Whole-Genome Sequence Data von Trost, Brett, Walker, Susan, Wang, Zhuozhi, Thiruvahindrapuram, Bhooma, MacDonald, Jeffrey R., Sung, Wilson W.L., Pereira, Sergio L., Whitney, Joe, Chan, Ada J.S., Pellecchia, Giovanna, Reuter, Miriam S., Lok, Si, Yuen, Ryan K.C., Marshall, Christian R., Merico, Daniele, Scherer, Stephen W.

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Genomic architecture of autism from comprehensive whole-genome sequence annotation von Trost, Brett, Thiruvahindrapuram, Bhooma, Chan, Ada J.S., Engchuan, Worrawat, Higginbotham, Edward J., Howe, Jennifer L., Loureiro, Livia O., Reuter, Miriam S., Roshandel, Delnaz, Whitney, Joe, Zarrei, Mehdi, Bookman, Matthew, Somerville, Cherith, Shaath, Rulan, Abdi, Mona, Aliyev, Elbay, Patel, Rohan V., Pellecchia, Giovanna, Hamdan, Omar, Kaur, Gaganjot, Wang, Zhuozhi, MacDonald, Jeffrey R., Wei, John, Sung, Wilson W.L., Lamoureux, Sylvia, Hoang, Ny, Selvanayagam, Thanuja, Deflaux, Nicole, Geng, Melissa, Ghaffari, Siavash, Bates, John, Young, Edwin J., Ding, Qiliang, Shum, Carole, D'Abate, Lia, Bradley, Clarrisa A., Rutherford, Annabel, Aguda, Vernie, Apresto, Beverly, Chen, Nan, Desai, Sachin, Du, Xiaoyan, Fong, Matthew L.Y., Pullenayegum, Sanjeev, Samler, Kozue, Wang, Ting, Ho, Karen, Paton, Tara, Pereira, Sergio L., Herbrick, Jo-Anne, Fuerth, Jonathan, Noppornpitak, Juti, Ward, Heather, Magee, Patrick, Al Baz, Ayman, Kajendirarajah, Usanthan, Vlasblom, Jim, Valluri, Monica, Green, Joseph, Seifer, Vicki, Quirbach, Morgan, Rennie, Olivia, Kelley, Elizabeth, Masjedi, Nina, Lord, Catherine, Szego, Michael J., Zawati, Ma'n H., Lang, Michael, Strug, Lisa J., Marshall, Christian R., Costain, Gregory, Calli, Kristina, Iaboni, Alana, Yusuf, Afiqah, Ambrozewicz, Patricia, Gallagher, Louise, Amaral, David G., Brian, Jessica, Elsabbagh, Mayada, Georgiades, Stelios, Messinger, Daniel S., Ozonoff, Sally, Sebat, Jonathan, Sjaarda, Calvin, Smith, Isabel M., Szatmari, Peter, Zwaigenbaum, Lonnie, Kushki, Azadeh, Frazier, Thomas W., Vorstman, Jacob A.S., Fakhro, Khalid A., Fernandez, Bridget A., Lewis, M.E. Suzanne, Weksberg, Rosanna, Fiume, Marc, Yuen, Ryan K.C., Anagnostou, Evdokia, Sondheimer, Neal, Glazer, David, Hartley, Dean M.

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A microcosting and cost–consequence analysis of clinical genomic testing strategies in autism spectrum disorder von Tsiplova, Kate, Zur, Richard M, Marshall, Christian R, Stavropoulos, Dimitri J, Pereira, Sergio L, Merico, Daniele, Young, Edwin J, Sung, Wilson W L, Scherer, Stephen W, Ungar, Wendy J

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Long-Read Sequencing Improves the Detection of Structural Variations Impacting Complex Non-Coding Elements of the Genome von Begum, Ghausia, Albanna, Ammar, Bankapur, Asma, Nassir, Nasna, Tambi, Richa, Berdiev, Bakhrom K, Akter, Hosneara, Karuvantevida, Noushad, Kellam, Barbara, Alhashmi, Deena, Sung, Wilson W L, Thiruvahindrapuram, Bhooma, Alsheikh-Ali, Alawi, Scherer, Stephen W, Uddin, Mohammed

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Genome-wide rare variant score associates with morphological subtypes of autism spectrum disorder von Chan, Ada J. S., Engchuan, Worrawat, Reuter, Miriam S., Wang, Zhuozhi, Thiruvahindrapuram, Bhooma, Trost, Brett, Nalpathamkalam, Thomas, Negrijn, Carol, Lamoureux, Sylvia, Pellecchia, Giovanna, Patel, Rohan V., Sung, Wilson W. L., MacDonald, Jeffrey R., Howe, Jennifer L., Vorstman, Jacob, Sondheimer, Neal, Takahashi, Nicole, Miles, Judith H., Anagnostou, Evdokia, Tammimies, Kristiina, Zarrei, Mehdi, Merico, Daniele, Stavropoulos, Dimitri J., Yuen, Ryan K. C., Fernandez, Bridget A., Scherer, Stephen W.

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Coding and long non-coding RNAs provide evidence of distinct transcriptional reprogramming for two ecotypes of the extremophile plant Eutrema salsugineum undergoing water deficit s... von Simopoulos, Caitlin M A, MacLeod, Mitchell J R, Irani, Solmaz, Sung, Wilson W L, Champigny, Marc J, Summers, Peter S, Golding, G Brian, Weretilnyk, Elizabeth A

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Genome Sequencing as a Diagnostic Test in Children With Unexplained Medical Complexity von Costain, Gregory, Walker, Susan, Marano, Maria, Veenma, Danielle, Snell, Meaghan, Curtis, Meredith, Luca, Stephanie, Buera, Jason, Arje, Danielle, Reuter, Miriam S, Thiruvahindrapuram, Bhooma, Trost, Brett, Sung, Wilson W L, Yuen, Ryan K C, Chitayat, David, Mendoza-Londono, Roberto, Stavropoulos, D James, Scherer, Stephen W, Marshall, Christian R, Cohn, Ronald D, Cohen, Eyal, Orkin, Julia, Meyn, M Stephen, Hayeems, Robin Z

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Acclimation of the crucifer Eutrema salsugineum to phosphate limitation is associated with constitutively high expression of phosphate‐starvation genes von Velasco, Vera Marjorie Elauria, Mansbridge, John, Bremner, Samantha, Carruthers, Kimberley, Summers, Peter S., Sung, Wilson W.L., Champigny, Marc J., Weretilnyk, Elizabeth A.

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Prevalence of Low-Frequency, Antiviral Resistance Variants in SARS-CoV-2 Isolates in Ontario, Canada, 2020-2023 von Sjaarda, Calvin P, Lau, Lynette, Simpson, Jared T, Fattouh, Ramzi, Biondi, Mia J, Maguire, Finlay, Campigotto, Aaron, Feng, Yujia, Tozer, Kyla, Wong, Henry, Sung, Wilson W L, Kim, Sean, Marshall, Christian R, Sheth, Prameet M, Kozak, Robert

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RNA-Seq effectively monitors gene expression in Eutrema salsugineum plants growing in an extreme natural habitat and in controlled growth cabinet conditions von Champigny, Marc J, Sung, Wilson Wl, Catana, Vasile, Salwan, Rupa, Summers, Peter S, Dudley, Susan A, Provart, Nicholas J, Cameron, Robin K, Golding, G Brian, Weretilnyk, Elizabeth A

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Clinical Genetic Risk Variants Inform a Functional Protein Interaction Network for Tetralogy of Fallot von Reuter, Miriam S., Chaturvedi, Rajiv R., Jobling, Rebekah K., Pellecchia, Giovanna, Hamdan, Omar, Sung, Wilson W.L., Nalpathamkalam, Thomas, Attaluri, Pratyusha, Silversides, Candice K., Wald, Rachel M., Marshall, Christian R., Williams, Simon G., Keavney, Bernard D., Thiruvahindrapuram, Bhooma, Scherer, Stephen W., Bassett, Anne S.

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Exposure of two Eutrema salsugineum (Thellungiella salsuginea) accessions to water deficits reveals different coping strategies in response to drought von MacLeod, Mitchell J.R., Dedrick, Jeff, Ashton, Claire, Sung, Wilson W.L., Champigny, Marc J., Weretilnyk, Elizabeth A.

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Whole genome sequencing delineates regulatory, copy number, and cryptic splice variants in early onset cardiomyopathy von Lesurf, Robert, Said, Abdelrahman, Akinrinade, Oyediran, Breckpot, Jeroen, Delfosse, Kathleen, Liu, Ting, Yao, Roderick, Persad, Gabrielle, McKenna, Fintan, Noche, Ramil R., Oliveros, Winona, Mattioli, Kaia, Shah, Shreya, Miron, Anastasia, Yang, Qian, Meng, Guoliang, Yue, Michelle Chan Seng, Sung, Wilson W. L., Thiruvahindrapuram, Bhooma, Lougheed, Jane, Oechslin, Erwin, Mondal, Tapas, Bergin, Lynn, Smythe, John, Jayappa, Shashank, Rao, Vinay J., Shenthar, Jayaprakash, Dhandapany, Perundurai S., Semsarian, Christopher, Weintraub, Robert G., Bagnall, Richard D., Ingles, Jodie, Melé, Marta, Maass, Philipp G., Ellis, James, Scherer, Stephen W., Mital, Seema

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De Novo Genome and Transcriptome Assembly of the Canadian Beaver (Castor canadensis) von Lok, Si, Paton, Tara A, Wang, Zhuozhi, Kaur, Gaganjot, Walker, Susan, Yuen, Ryan K C, Sung, Wilson W L, Whitney, Joseph, Buchanan, Janet A, Trost, Brett, Singh, Naina, Apresto, Beverly, Chen, Nan, Coole, Matthew, Dawson, Travis J, Ho, Karen, Hu, Zhizhou, Pullenayegum, Sanjeev, Samler, Kozue, Shipstone, Arun, Tsoi, Fiona, Wang, Ting, Pereira, Sergio L, Rostami, Pirooz, Ryan, Carol Ann, Tong, Amy Hin Yan, Ng, Karen, Sundaravadanam, Yogi, Simpson, Jared T, Lim, Burton K, Engstrom, Mark D, Dutton, Christopher J, Kerr, Kevin C R, Franke, Maria, Rapley, William, Wintle, Richard F, Scherer, Stephen W

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Whole genome sequencing delineates regulatory, copy number, and cryptic splice variants in early onset cardiomyopathy von Lesurf, Robert, Said, Abdelrahman, Akinrinade, Oyediran, Breckpot, Jeroen, Delfosse, Kathleen, Liu, Ting, Yao, Roderick, Persad, Gabrielle, McKenna, Fintan, Noche, Ramil R, Oliveros, Winona, Mattioli, Kaia, Shah, Shreya, Miron, Anastasia, Yang, Qian, Meng, Guoliang, Yue, Michelle Chan Seng, Sung, Wilson W.L, Thiruvahindrapuram, Bhooma, Lougheed, Jane, Oechslin, Erwin, Mondal, Tapas, Bergin, Lynn, Smythe, John, Jayappa, Shashank, Rao, Vinay J, Shenthar, Jayaprakash, Dhandapany, Perundurai S, Semsarian, Christopher, Weintraub, Robert G, Bagnall, Richard D, Ingles, Jodie, Mele, Marta, Maass, Philipp G, Ellis, James, Scherer, Stephen W, Mital, Seema

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