Pharmacogenomic Prescribing Guidelines: Are They Always Useful? von Ingelman-Sundberg, Magnus

Volltext

Precision medicine in cardiovascular therapeutics: Evaluating the role of pharmacogenetic analysis prior to drug treatment von Ingelman-Sundberg, Magnus, Pirmohamed, Munir

Volltext

Endogenous and xenobiotic metabolic stability of primary human hepatocytes in long‐term 3D spheroid cultures revealed by a combination of targeted and untargeted metabolomics von Vorrink, Sabine U., Ullah, Shahid, Schmidt, Staffan, Nandania, Jatin, Velagapudi, Vidya, Beck, Olof, Ingelman‐Sundberg, Magnus, Lauschke, Volker M.

Volltext

The Pharmacogene Variation (PharmVar) Consortium: Incorporation of the Human Cytochrome P450 (CYP) Allele Nomenclature Database von Gaedigk, Andrea, Ingelman‐Sundberg, Magnus, Miller, Neil A., Leeder, J. Steven, Whirl‐Carrillo, Michelle, Klein, Teri E.

Volltext

3D human liver spheroids for translational pharmacology and toxicology von Ingelman‐Sundberg, Magnus, Lauschke, Volker M.

Volltext

Evaluation of Current Regulation and Guidelines of Pharmacogenomic Drug Labels: Opportunities for Improvements von Shekhani, Rawan, Steinacher, Linda, Swen, Jesse J., Ingelman‐Sundberg, Magnus

Volltext

Therapeutic drug monitoring, liquid biopsies or pharmacogenomics for prediction of human drug metabolism and response von Ingelman-Sundberg, Magnus, Molden, Espen

Volltext

How to Consider Rare Genetic Variants in Personalized Drug Therapy von Lauschke, Volker M., Ingelman‐Sundberg, Magnus

Volltext

Development of the PGx‐Passport: A Panel of Actionable Germline Genetic Variants for Pre‐Emptive Pharmacogenetic Testing von Wouden, Cathelijne H., van Rhenen, Mandy H., Jama, Wafa O.M., Ingelman‐Sundberg, Magnus, Lauschke, Volker M., Konta, Lidija, Schwab, Matthias, Swen, Jesse J., Guchelaar, Henk‐Jan

Volltext

Mechanistic, Functional, and Clinical Aspects of Pro‐inflammatory Cytokine Mediated Regulation of ADME Gene Expression in 3D Human Liver Spheroids von Klöditz, Katharina, Tewolde, Eida, Nordling, Åsa, Ingelman‐Sundberg, Magnus

Volltext

Liquid Biopsies or Therapeutic Drug Monitoring for CYP Activity Profile Determination von Pridgeon, Chris S., Johansson, Inger, Ingelman‐Sundberg, Magnus

Volltext

3D Spheroid Primary Human Hepatocytes for Prediction of Cytochrome P450 and Drug Transporter Induction von Järvinen, Erkka, Hammer, Helen S., Pötz, Oliver, Ingelman‐Sundberg, Magnus, Stage, Tore Bjerregaard

Volltext

Evaluation of the CYP2D6 Haplotype Activity Scores Based on Metabolic Ratios of 4,700 Patients Treated With Three Different CYP2D6 Substrates von Jukić, Marin M., Smith, Robert L., Molden, Espen, Ingelman‐Sundberg, Magnus

Volltext

3D Primary Hepatocyte Culture Systems for Analyses of Liver Diseases, Drug Metabolism, and Toxicity: Emerging Culture Paradigms and Applications von Lauschke, Volker M., Shafagh, Reza Z., Hendriks, Delilah F. G., Ingelman‐Sundberg, Magnus

Volltext

Current level of evidence for improvement of antidepressant efficacy and tolerability by pharmacogenomic-guided treatment: A Systematic review and meta-analysis of randomized contr... von Milosavljević, Filip, Molden, Prof. Espen, Ingelman-Sundberg, Prof. Magnus, Jukić, Assoc. Prof. Marin M

Volltext

Clinically Relevant Cytochrome P450 3A4 Induction Mechanisms and Drug Screening in Three‐Dimensional Spheroid Cultures of Primary Human Hepatocytes von Hendriks, Delilah F.G., Vorrink, Sabine U., Smutny, Tomas, Sim, Sarah C., Nordling, Åsa, Ullah, Shahid, Kumondai, Masaki, Jones, Barry C., Johansson, Inger, Andersson, Tommy B., Lauschke, Volker M., Ingelman‐Sundberg, Magnus

Volltext

A Novel CYP2C‐Haplotype Associated With Ultrarapid Metabolism of Escitalopram von Bråten, Line Skute, Haslemo, Tore, Jukic, Marin M., Ivanov, Maxim, Ingelman‐Sundberg, Magnus, Molden, Espen, Kringen, Marianne Kristiansen

Volltext

Response to Rowland et al. and Achour et al von Pridgeon, Chris S., Johansson, Inger, Ingelman‐Sundberg, Magnus

Volltext

Massive rearrangements of cellular MicroRNA signatures are key drivers of hepatocyte dedifferentiation von Lauschke, Volker M., Vorrink, Sabine U., Moro, Sabrina M.L., Rezayee, Fatemah, Nordling, Åsa, Hendriks, Delilah F.G., Bell, Catherine C., Sison‐Young, Rowena, Park, B. Kevin, Goldring, Christopher E., Ellis, Ewa, Johansson, Inger, Mkrtchian, Souren, Andersson, Tommy B., Ingelman‐Sundberg, Magnus

Volltext

CYP2E1 in Alcoholic and Non-Alcoholic Liver Injury. Roles of ROS, Reactive Intermediates and Lipid Overload von Harjumäki, Riina, Pridgeon, Chris S., Ingelman-Sundberg, Magnus

Volltext