Hsp90β knockdown in DIO mice reverses insulin resistance and improves glucose tolerance von Jing, Enxuan, Sundararajan, Pragalath, Majumdar, Ishita Deb, Hazarika, Suwagmani, Fowler, Samantha, Szeto, Angela, Gesta, Stephane, Mendez, Armando J, Vishnudas, Vivek K, Sarangarajan, Rangaprasad, Narain, Niven R

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Abstract 2943: Interrogative Biology® platform identifies a novel target in the ubiquitin pathway and its utility in cancer is supported by small molecule modulators von Gesta, Stephane, Sharma, Shefali, Sundararajan, Pragalath, Huang, Mingshu, Gray, Kayleigh, Nastke, Maria, Guven, Arcan, Diers, Anne, Kazerounian, Shiva, Hazarika, Suwagmani, Grund, Eric M., Vishnudas, Vivek K., Narain, Niven R., Sarangarajan, Rangaprasad

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Hsp90[beta] knockdown in DIO mice reverses insulin resistance and improves glucose tolerance von Jing, Enxuan, Sundararajan, Pragalath, Majumdar, Ishita Deb, Hazarika, Suwagmani, Fowler, Samantha, Szeto, Angela, Gesta, Stephane, Mendez, Armando J, Vishnudas, Vivek K, Sarangarajan, Rangaprasad, Narain, Niven R

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Abstract 5321: BRG399: A novel potent small molecule modulator of UBE2K for the treatment of various cancers von Nastke, Maria-Dorothea, Permatteo, Marisa, Sundararajan, Pragalath, Sharma, Shefali, Matson, Jacob, Gray, Kaleigh, Guven, Arcan, Kazerounian, Shiva, Diers, Anne, Sarangarajan, Rangaprasad, Narain, Niven R., Vishnudas, Vivek K., Gesta, Stephane

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Abstract 5542: Identification of Enolase1 as key drug target in breast cancer by the Berg Interrogative Biology™ platform von Jing, Enxuan, Hazarika, Suwagmani, Sundararajan, Pragalath, Fowler, Samantha, Vishnudas, Vivek K., Sarangarajan, Rangaprasad, Narain, Niven R.

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Abstract 5319: Treatment of K562 leukemia cells with an experimental UBE2K modifier identifies multi-omic changes associated with altered oncogenic processes von Shah, Punit, Searfoss, Richard, Bussberg, Valerie, Greenwood, Bennett, Karmacharya, Shraddha, MacDonald, Allison, Ofori-Mensa, Kennedy, Tolstikov, Vladimir, Sundararajan, Pragalath, Nastke, Maria-Dorothea, Grund, Eric M., Miller, Gregory M., Gesta, Stephane, Sarangarajan, Rangaprasad, Granger, Elder, Narain, Niven R., Vishnudas, Vivek K., Kiebish, Michael A.

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Abstract 2719: MM-141, a novel bispecific antibody co-targeting IGF-1R and ErbB3, blocks ligand-induced signaling and demonstrates antitumor activity von Baum, Jason, Johnson, Bryan, Adams, Sharlene, Tang, Jian, Kohli, Neeraj, Rennard, Rachel, Sundararajan, Pragalath, Xu, Lihui, Jiao, Yang, Schoeberl, Birgit, Nielsen, Ulrik, Fitzgerald, Jonathan, Lugovskoy, Alexey

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