CDK4/6 inhibition synergizes with inhibition of P21-Activated Kinases (PAKs) in lung cancer cell lines von Wright, Gabriela M., Gimbrone, Nick T., Sarcar, Bhaswati, Percy, Trent R., Gordian, Edna R., Kinose, Fumi, Sumi, Natalia J., Rix, Uwe, Cress, W. Douglas

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IGF-binding proteins secreted by cancer-associated fibroblasts induce context-dependent drug sensitization of lung cancer cells von Remsing Rix, Lily L, Sumi, Natalia J, Hu, Qianqian, Desai, Bina, Bryant, Annamarie T, Li, Xueli, Welsh, Eric A, Fang, Bin, Kinose, Fumi, Kuenzi, Brent M, Chen, Y Ann, Antonia, Scott J, Lovly, Christine M, Koomen, John M, Haura, Eric B, Marusyk, Andriy, Rix, Uwe

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Chemoproteomics Reveals Novel Protein and Lipid Kinase Targets of Clinical CDK4/6 Inhibitors in Lung Cancer von Sumi, Natalia J, Kuenzi, Brent M, Knezevic, Claire E, Remsing Rix, Lily L, Rix, Uwe

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Clostridium perfringens enterotoxin C‐terminal domain labeled to fluorescent dyes for in vivo visualization of micrometastatic chemotherapy‐resistant ovarian cancer von Cocco, Emiliano, Shapiro, Erik M., Gasparrini, Sara, Lopez, Salvatore, Schwab, Carlton L., Bellone, Stefania, Bortolomai, Ileana, Sumi, Natalia J., Bonazzoli, Elena, Nicoletti, Roberta, Deng, Yang, Saltzman, W. Mark, Zeiss, Caroline J., Centritto, Floriana, Black, Jonathan D., Silasi, Dan‐Arin, Ratner, Elena, Azodi, Masoud, Rutherford, Thomas J., Schwartz, Peter E., Pecorelli, Sergio, Santin, Alessandro D.

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p53-Pirh2 Complex Promotes Twist1 Degradation and Inhibits EMT von Yang-Hartwich, Yang, Tedja, Roslyn, Roberts, Cai M, Goodner-Bingham, Jamie, Cardenas, Carlos, Gurea, Marta, Sumi, Natalia J, Alvero, Ayesha B, Glackin, Carlotta A, Mor, Gil

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Phenotypic modifications in ovarian cancer stem cells following Paclitaxel treatment von Craveiro, Vinicius, Yang‐Hartwich, Yang, Holmberg, Jennie C., Sumi, Natalia J., Pizzonia, John, Griffin, Brian, Gill, Sabrina K., Silasi, Dan‐Arin, Azodi, Masoud, Rutherford, Thomas, Alvero, Ayesha B., Mor, Gil

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Divergent Polypharmacology-Driven Cellular Activity of Structurally Similar Multi-Kinase Inhibitors through Cumulative Effects on Individual Targets von Sumi, Natalia J., Ctortecka, Claudia, Hu, Qianqian, Bryant, Annamarie T., Fang, Bin, Remsing Rix, Lily L., Ayaz, Muhammad, Kinose, Fumi, Welsh, Eric A., Eschrich, Steven A., Lawrence, Harshani R., Koomen, John M., Haura, Eric B., Rix, Uwe

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Functional Proteomics and Deep Network Interrogation Reveal a Complex Mechanism of Action of Midostaurin in Lung Cancer Cells von Ctortecka, Claudia, Palve, Vinayak, Kuenzi, Brent M., Fang, Bin, Sumi, Natalia J., Izumi, Victoria, Novakova, Silvia, Kinose, Fumi, Remsing Rix, Lily L., Haura, Eric B., Koomen, John Matthew, Rix, Uwe

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Multiple blocks in the engagement of oxidative phosphorylation in putative ovarian cancer stem cells: implication for maintenance therapy with glycolysis inhibitors von Alvero, Ayesha B, Montagna, Michele K, Sumi, Natalia J, Joo, Won Duk, Graham, Emma, Mor, Gil

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CDK4/6 inhibition synergizes with inhibition of P21-Activated Kinases von Wright, Gabriela M, Gimbrone, Nick T, Sarcar, Bhaswati, Percy, Trent R, Gordián, Edna R, Kinose, Fumi, Sumi, Natália J, Rix, Uwe, Cress, W. Douglas

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Murine model for non-invasive imaging to detect and monitor ovarian cancer recurrence von Sumi, Natalia J, Lima, Eydis, Pizzonia, John, Orton, Sean P, Craveiro, Vinicius, Joo, Wonduk, Holmberg, Jennie C, Gurrea, Marta, Yang-Hartwich, Yang, Alvero, Ayesha, Mor, Gil

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Phenotypic modifications in ovarian cancer stem cells following Paclitaxel treatment von Craveiro, Vinicius, Yang‐Hartwich, Yang, Holmberg, Jennie C., Sumi, Natalia J., Pizzonia, John, Griffin, Brian, Gill, Sabrina K., Silasi, Dan‐Arin, Azodi, Masoud, Rutherford, Thomas, Alvero, Ayesha B., Mor, Gil

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Abstract C110: Cancer associated fibroblast-derived IGF-binding proteins augment osimertinib activity in EGFR-mutant NSCLC cells von Rix, Lily L. Remsing, Sumi, Natalia J., Bryant, Annamarie T., Li, Xueli, Welsh, Eric A., Fang, Bin, Kuenzi, Brent M., Antonia, Scott J., Marusyk, Andriy, Lovly, Christine M., Koomen, John M., Haura, Eric B., Rix, Uwe

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Abstract 4319: Inability of putative ovarian cancer stem cells to engage OXPHOS confer 2-deoxyglucose-mediated prevention of in vivo recurrence von Alvero, Ayesha B., Montagna, Michele, Sumi, Natalia J., Joo, Won Duk, Craveiro, Vinicius, Graham, Emma, Mor, Gil

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Clostridium Perfringens Enterotoxin C-terminal domain labeled to fluorescent Dyes for in vivo visualization of micro-metastatic chemotherapy-resistant ovarian cancer von Cocco, Emiliano, Shapiro, Erik M., Gasparrini, Sara, Lopez, Salvatore, Schwab, Carlton L., Bellone, Stefania, Bortolomai, Ileana, Sumi, Natalia J., Bonazzoli, Elena, Nicoletti, Roberta, Deng, Yang, Saltzman, W. Mark, Zeiss, Caroline J., Centritto, Floriana, Black, Jonathan D., Silasi, Dan-Arin, Ratner, Elena, Azodi, Masoud, Rutherford, Thomas J., Schwartz, Peter E., Pecorelli, Sergio, Santin, Alessandro D.

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Abstract 4937: Fluorescence imaging using Clostridium Perfringens Enterotoxin carboxi-terminal fragment (c-CPE) to target metastatic chemotherapy-resistant human ovarian cancer in... von Cocco, Emiliano, Gasparrini, Sara, Shapiro, Erik M., Schwab, Carlton, Bellone, Stefania, Bortolomai, Ileana, Lopez, Salvatore, Sumi, Natalia J., Bonazzoli, Elena, Nicoletti, Roberta, Deng, Yang, Saltzman, William M., Zeiss, Caroline J., Silasi, Dan-Arin, Rutherford, Thomas J., Schwartz, Peter E., Santin, Alessandro D.

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Murine Model for Non-invasive Imaging to Detect and Monitor Ovarian Cancer Recurrence von Sumi, Natalia J., Lima, Eydis, Pizzonia, John, Orton, Sean P., Craveiro, Vinicius, Joo, Wonduk, Holmberg, Jennie C., Gurrea, Marta, Yang-Hartwich, Yang, Alvero, Ayesha, Mor, Gil

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