FAK in cancer: mechanistic findings and clinical applications von Sulzmaier, Florian J., Jean, Christine, Schlaepfer, David D.

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RSK Isoforms in Cancer Cell Invasion and Metastasis von SULZMAIER, Florian J, RAMOS, Joe W

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FAK Inhibition disrupts a β5 integrin signaling axis controlling anchorage-independent ovarian carcinoma growth von Tancioni, Isabelle, Uryu, Sean, Sulzmaier, Florian J, Shah, Nina R, Lawson, Christine, Miller, Nichol L G, Jean, Christine, Chen, Xiao Lei, Ward, Kristy K, Schlaepfer, David D

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Englerin a selectively induces necrosis in human renal cancer cells von Sulzmaier, Florian J, Li, Zhenwu, Nakashige, Mika L, Fash, David M, Chain, William J, Ramos, Joe W

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Oxidized LDL induces FAK-dependent RSK signaling to drive NF-κB activation and VCAM-1 expression von Yurdagul, Jr, Arif, Sulzmaier, Florian J, Chen, Xiao L, Pattillo, Christopher B, Schlaepfer, David D, Orr, A Wayne

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Organometallic Titanocene–Gold Compounds as Potential Chemotherapeutics in Renal Cancer. Study of their Protein Kinase Inhibitory Properties von Fernández-Gallardo, Jacob, Elie, Benelita T, Sulzmaier, Florian J, Sanaú, Mercedes, Ramos, Joe W, Contel, María

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Analyses of merlin/NF2 connection to FAK inhibitor responsiveness in serous ovarian cancer von Shah, Nina R, Tancioni, Isabelle, Ward, Kristy K, Lawson, Christine, Chen, Xiao Lei, Jean, Christine, Sulzmaier, Florian J, Uryu, Sean, Miller, Nichol L.G, Connolly, Denise C, Schlaepfer, David D

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RSK2 activity mediates glioblastoma invasiveness and is a potential target for new therapeutics von Sulzmaier, Florian J, Young-Robbins, Shirley, Jiang, Pengfei, Geerts, Dirk, Prechtl, Amanda M, Matter, Michelle L, Kesari, Santosh, Ramos, Joe W

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RSK2 Protein Suppresses Integrin Activation and Fibronectin Matrix Assembly and Promotes Cell Migration von Gawecka, Joanna E., Young-Robbins, Shirley S., Sulzmaier, Florian J., Caliva, Maisel J., Heikkilä, Minna M., Matter, Michelle L., Ramos, Joe W.

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Neopetrocyclamines A and B, Polycyclic Diamine Alkaloids from the Sponge Neopetrosia cf exigua von Liang, Zhibin, Sulzmaier, Florian J, Yoshida, Wesley Y, Kelly, Michelle, Ramos, Joe W, Williams, Philip G

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INBRX-120, a CD8α-targeted detuned IL-2 that selectively expands and activates tumoricidal effector cells for safe and durable in vivo responses von Sulzmaier, Florian J, Kern, Nadja, Ahn, Sae Jeong, Polovina, Anya, Ho, Jason, Hussain, Abrahim, Cyprus, Garrett, Macedo, Chelsie, Pandit, Rajay, Crago, William, Rowell, Emily, Timmer, John C, Eckelman, Brendan P

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FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy von Diaz Osterman, Carlos J, Ozmadenci, Duygu, Kleinschmidt, Elizabeth G, Taylor, Kristin N, Barrie, Allison M, Jiang, Shulin, Bean, Lisa M, Sulzmaier, Florian J, Jean, Christine, Tancioni, Isabelle, Anderson, Kristen, Uryu, Sean, Cordasco, Edward A, Li, Jian, Chen, Xiao Lei, Fu, Guo, Ojalill, Marjaana, Rappu, Pekka, Heino, Jyrki, Mark, Adam M, Xu, Guorong, Fisch, Kathleen M, Kolev, Vihren N, Weaver, David T, Pachter, Jonathan A, Győrffy, Balázs, McHale, Michael T, Connolly, Denise C, Molinolo, Alfredo, Stupack, Dwayne G, Schlaepfer, David D

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Phosphorylation is the switch that turns PEA-15 from tumor suppressor to tumor promoter von Sulzmaier, Florian J., Opoku-Ansah, John, Ramos, Joe W.

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12 Key pharmacokinetic and pharmacodynamic parameters that correlate with the anti-tumor activity of a bispecific PD-L1 conditional 4–1BB agonist von Kinkead, Heather, Macedo, Chelsie, Sanabria, Angelica, Cyprus, Garrett, Pandit, Rajay, Kalabus, James, Becklund, Bryan, Sulzmaier, Florian, Timmer, John, Deveraux, Quinn, Eckelman, Brendan, Heidt, Analeah

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Synthesis of a stable and orally bioavailable englerin analogue von Fash, David M., Peer, Cody J., Li, Zhenwu, Talisman, Ian J., Hayavi, Sima, Sulzmaier, Florian J., Ramos, Joe W., Sourbier, Carole, Neckers, Leonard, Figg, W. Douglas, Beutler, John A., Chain, William J.

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856 INBRX-106: a novel hexavalent anti-OX40 agonist for the treatment of solid tumors von Rowell, Emily, Kinkead, Heather, Torretti, Elisabeth, Becklund, Bryan, Sulzmaier, Florian, Crago, William, Jones, Kyle, Timmer, John, Deveraux, Quinn, Eckelman, Brendan, Heidt, Analeah

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722 INBRX-121 is an NKp46-targeted detuned IL-2 with antitumor activity as a monotherapy or in combination with multiple cancer immunotherapy modalities von Sulzmaier, Florian, Kinkead, Heather, Polovina, Anya, Kern, Nadja, Sanabria, Angelica, Macedo, Chelsie, Hussain, Abrahim, Ahn, Sae Jeong, Pandit, Rajay, Crago, William, Timmer, John, Heidt, Analeah, Eckelman, Brendan

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Stictamides A−C, MMP12 Inhibitors Containing 4-Amino-3-hydroxy-5-phenylpentanoic Acid Subunits von Liang, Zhibin, Sorribas, Analia, Sulzmaier, Florian J, Jiménez, Jorge I, Wang, Xin, Sauvage, Thomas, Yoshida, Wesley Y, Wang, Guangyi, Ramos, Joe W, Williams, Philip G

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PEA15 impairs cell migration and correlates with clinical features predicting good prognosis in neuroblastoma von Gawecka, Joanna E., Geerts, Dirk, Koster, Jan, Caliva, Maisel J., Sulzmaier, Florian J., Opoku-Ansah, John, Wada, Randal K., Bachmann, André S., Ramos, Joe W.

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High dose of dietary resveratrol enhances insulin sensitivity in healthy rats but does not lead to metabolite concentrations effective for SIRT1 expression von Andersen, Gaby, Burkon, Alexander, Sulzmaier, Florian J., Walker, Joel M., Leckband, Gunhild, Fuhst, Rainer, Erbersdobler, Helmut F., Somoza, Veronika

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