Nutrient Competition: A New Axis of Tumor Immunosuppression von Sukumar, Madhusudhanan, Roychoudhuri, Rahul, Restifo, Nicholas P.

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T cell stemness and dysfunction in tumors are triggered by a common mechanism von Vodnala, Suman Kumar, Eil, Robert, Kishton, Rigel J, Sukumar, Madhusudhanan, Yamamoto, Tori N, Ha, Ngoc-Han, Lee, Ping-Hsien, Shin, MinHwa, Patel, Shashank J, Yu, Zhiya, Palmer, Douglas C, Kruhlak, Michael J, Liu, Xiaojing, Locasale, Jason W, Huang, Jing, Roychoudhuri, Rahul, Finkel, Toren, Klebanoff, Christopher A, Restifo, Nicholas P

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Identification of essential genes for cancer immunotherapy von Patel, Shashank J., Sanjana, Neville E., Kishton, Rigel J., Eidizadeh, Arash, Vodnala, Suman K., Cam, Maggie, Gartner, Jared J., Jia, Li, Steinberg, Seth M., Yamamoto, Tori N., Merchant, Anand S., Mehta, Gautam U., Chichura, Anna, Shalem, Ophir, Tran, Eric, Eil, Robert, Sukumar, Madhusudhanan, Guijarro, Eva Perez, Day, Chi-Ping, Robbins, Paul, Feldman, Steve, Merlino, Glenn, Zhang, Feng, Restifo, Nicholas P.

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Metabolic reprograming of anti-tumor immunity von Sukumar, Madhusudhanan, Kishton, Rigel J, Restifo, Nicholas P

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miR-155 augments CD8⁺ T-cell antitumor activity in lymphoreplete hosts by enhancing responsiveness to homeostatic γc cytokines von Ji, Yun, Wrzesinski, Claudia, Yu, Zhiya, Hu, Jinhui, Gautam, Sanjivan, Hawk, Nga V, Telford, William G, Palmer, Douglas C, Franco, Zulmarie, Sukumar, Madhusudhanan, Roychoudhuri, Rahul, Clever, David, Klebanoff, Christopher A, Surh, Charles D, Waldmann, Thomas A, Restifo, Nicholas P, Gattinoni, Luca

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Lineage relationship of CD8^＋ T cell subsets is revealed by progressive changes in the epigenetic landscape von Crompton, Joseph G., Narayanan, Manikandan, Cuddapah, Suresh, Roychoudhuri, Rahul, Ji, Yun, Yang, Wenjing, Patel, Shashank J., Sukumar, Madhusudhanan, Palmer, Douglas C., Peng, Weiqun, Wang, Ena, Marincola, Francesco M., Klebanoff, Christopher A., Zhao, Keji, Tsang, John S., Gattinoni, Luca, Restifo, Nicholas P.

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Retinoic acid controls the homeostasis of pre-cDC-derived splenic and intestinal dendritic cells von Klebanoff, Christopher A, Spencer, Sean P, Torabi-Parizi, Parizad, Grainger, John R, Roychoudhuri, Rahul, Ji, Yun, Sukumar, Madhusudhanan, Muranski, Pawel, Scott, Christopher D, Hall, Jason A, Ferreyra, Gabriela A, Leonardi, Anthony J, Borman, Zachary A, Wang, Jinshan, Palmer, Douglas C, Wilhelm, Christoph, Cai, Rongman, Sun, Junfeng, Napoli, Joseph L, Danner, Robert L, Gattinoni, Luca, Belkaid, Yasmine, Restifo, Nicholas P

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The transcription factor BACH2 promotes tumor immunosuppression von Roychoudhuri, Rahul, Eil, Robert L, Clever, David, Klebanoff, Christopher A, Sukumar, Madhusudhanan, Grant, Francis M, Yu, Zhiya, Mehta, Gautam, Liu, Hui, Jin, Ping, Ji, Yun, Palmer, Douglas C, Pan, Jenny H, Chichura, Anna, Crompton, Joseph G, Patel, Shashank J, Stroncek, David, Wang, Ena, Marincola, Francesco M, Okkenhaug, Klaus, Gattinoni, Luca, Restifo, Nicholas P

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Metabolic Regulation of T Cell Longevity and Function in Tumor Immunotherapy von Kishton, Rigel J., Sukumar, Madhusudhanan, Restifo, Nicholas P.

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Mitochondrial Membrane Potential Identifies Cells with Enhanced Stemness for TCR and CAR based Adoptive Immunotherapy of Cancer von Sukumar, Madhusudhanan, Restifo, Nicholas

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Stromal interferon-γ signaling and cross-presentation are required to eliminate antigen-loss variants of B cell lymphomas in mice von Gerbitz, Armin, Sukumar, Madhusudhanan, Helm, Florian, Wilke, Andrea, Friese, Christian, Fahrenwaldt, Cornelia, Lehmann, Frank M, Loddenkemper, Christoph, Kammertoens, Thomas, Mautner, Josef, Schmitt, Clemens A, Blankenstein, Thomas, Bornkamm, Georg W

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Uncoupling T-cell expansion from effector differentiation in cell-based immunotherapy von Crompton, Joseph G., Sukumar, Madhusudhanan, Restifo, Nicholas P.

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Inhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function von Sukumar, Madhusudhanan, Liu, Jie, Ji, Yun, Subramanian, Murugan, Crompton, Joseph G, Yu, Zhiya, Roychoudhuri, Rahul, Palmer, Douglas C, Muranski, Pawel, Karoly, Edward D, Mohney, Robert P, Klebanoff, Christopher A, Lal, Ashish, Finkel, Toren, Restifo, Nicholas P, Gattinoni, Luca

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Ionic immune suppression within the tumour microenvironment limits T cell effector function von Eil, Robert, Vodnala, Suman K., Clever, David, Klebanoff, Christopher A., Sukumar, Madhusudhanan, Pan, Jenny H., Palmer, Douglas C., Gros, Alena, Yamamoto, Tori N., Patel, Shashank J., Guittard, Geoffrey C., Yu, Zhiya, Carbonaro, Valentina, Okkenhaug, Klaus, Schrump, David S., Linehan, W. Marston, Roychoudhuri, Rahul, Restifo, Nicholas P.

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Oxygen Sensing by T Cells Establishes an Immunologically Tolerant Metastatic Niche von Clever, David, Roychoudhuri, Rahul, Constantinides, Michael G., Askenase, Michael H., Sukumar, Madhusudhanan, Klebanoff, Christopher A., Eil, Robert L., Hickman, Heather D., Yu, Zhiya, Pan, Jenny H., Palmer, Douglas C., Phan, Anthony T., Goulding, John, Gattinoni, Luca, Goldrath, Ananda W., Belkaid, Yasmine, Restifo, Nicholas P.

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BACH2 regulates CD8+ T cell differentiation by controlling access of AP-1 factors to enhancers von Roychoudhuri, Rahul, Clever, David, Li, Peng, Wakabayashi, Yoshiyuki, Quinn, Kylie M, Klebanoff, Christopher A, Ji, Yun, Sukumar, Madhusudhanan, Eil, Robert L, Yu, Zhiya, Spolski, Rosanne, Palmer, Douglas C, Pan, Jenny H, Patel, Shashank J, Macallan, Derek C, Fabozzi, Giulia, Shih, Han-Yu, Kanno, Yuka, Muto, Akihiko, Zhu, Jun, Gattinoni, Luca, O'Shea, John J, Okkenhaug, Klaus, Igarashi, Kazuhiko, Leonard, Warren J, Restifo, Nicholas P

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Akt inhibition enhances expansion of potent tumor-specific lymphocytes with memory cell characteristics von Crompton, Joseph G, Sukumar, Madhusudhanan, Roychoudhuri, Rahul, Clever, David, Gros, Alena, Eil, Robert L, Tran, Eric, Hanada, Ken-Ichi, Yu, Zhiya, Palmer, Douglas C, Kerkar, Sid P, Michalek, Ryan D, Upham, Trevor, Leonardi, Anthony, Acquavella, Nicolas, Wang, Ena, Marincola, Francesco M, Gattinoni, Luca, Muranski, Pawel, Sundrud, Mark S, Klebanoff, Christopher A, Rosenberg, Steven A, Fearon, Douglas T, Restifo, Nicholas P

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Mitochondrial Membrane Potential Identifies Cells with Enhanced Stemness for Cellular Therapy von Sukumar, Madhusudhanan, Liu, Jie, Mehta, Gautam U., Patel, Shashank J., Roychoudhuri, Rahul, Crompton, Joseph G., Klebanoff, Christopher A., Ji, Yun, Li, Peng, Yu, Zhiya, Whitehill, Greg D., Clever, David, Eil, Robert L., Palmer, Douglas C., Mitra, Suman, Rao, Mahadev, Keyvanfar, Keyvan, Schrump, David S., Wang, Ena, Marincola, Francesco M., Gattinoni, Luca, Leonard, Warren J., Muranski, Pawel, Finkel, Toren, Restifo, Nicholas P.

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Memory T cell-driven differentiation of naive cells impairs adoptive immunotherapy von Klebanoff, Christopher A, Scott, Christopher D, Leonardi, Anthony J, Yamamoto, Tori N, Cruz, Anthony C, Ouyang, Claudia, Ramaswamy, Madhu, Roychoudhuri, Rahul, Ji, Yun, Eil, Robert L, Sukumar, Madhusudhanan, Crompton, Joseph G, Palmer, Douglas C, Borman, Zachary A, Clever, David, Thomas, Stacy K, Patel, Shashankkumar, Yu, Zhiya, Muranski, Pawel, Liu, Hui, Wang, Ena, Marincola, Francesco M, Gros, Alena, Gattinoni, Luca, Rosenberg, Steven A, Siegel, Richard M, Restifo, Nicholas P

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Host conditioning with IL-1β improves the antitumor function of adoptively transferred T cells von Lee, Ping-Hsien, Yamamoto, Tori N, Gurusamy, Devikala, Sukumar, Madhusudhanan, Yu, Zhiya, Hu-Li, Jane, Kawabe, Takeshi, Gangaplara, Arunakumar, Kishton, Rigel J, Henning, Amanda N, Vodnala, Suman K, Germain, Ronald N, Paul, William E, Restifo, Nicholas P

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