DprE2 is a molecular target of the anti-tubercular nitroimidazole compounds pretomanid and delamanid von Abrahams, Katherine A., Batt, Sarah M., Gurcha, Sudagar S., Veerapen, Natacha, Bashiri, Ghader, Besra, Gurdyal S.

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Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol von Zhang, Lu, Zhao, Yao, Gao, Yan, Wu, Lijie, Gao, Ruogu, Zhang, Qi, Wang, Yinan, Wu, Chengyao, Wu, Fangyu, Gurcha, Sudagar S, Veerapen, Natacha, Batt, Sarah M, Zhao, Wei, Qin, Ling, Yang, Xiuna, Wang, Manfu, Zhu, Yan, Zhang, Bing, Bi, Lijun, Zhang, Xian'en, Yang, Haitao, Guddat, Luke W, Xu, Wenqing, Wang, Quan, Li, Jun, Besra, Gurdyal S, Rao, Zihe

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Cord factor and peptidoglycan recapitulate the Th17-promoting adjuvant activity of mycobacteria through mincle/CARD9 signaling and the inflammasome von Shenderov, Kevin, Barber, Daniel L, Mayer-Barber, Katrin D, Gurcha, Sudagar S, Jankovic, Dragana, Feng, Carl G, Oland, Sandy, Hieny, Sara, Caspar, Pat, Yamasaki, Sho, Lin, Xin, Ting, Jenny P-Y, Trinchieri, Giorgio, Besra, Gurdyal S, Cerundolo, Vincenzo, Sher, Alan

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The mycobacterial glycoside hydrolase LamH enables capsular arabinomannan release and stimulates growth von Franklin, Aaron, Salgueiro, Vivian C., Layton, Abigail J., Sullivan, Rudi, Mize, Todd, Vázquez-Iniesta, Lucía, Benedict, Samuel T., Gurcha, Sudagar S., Anso, Itxaso, Besra, Gurdyal S., Banzhaf, Manuel, Lovering, Andrew L., Williams, Spencer J., Guerin, Marcelo E., Scott, Nichollas E., Prados-Rosales, Rafael, Lowe, Elisabeth C., Moynihan, Patrick J.

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Author Correction: The mycobacterial glycoside hydrolase LamH enables capsular arabinomannan release and stimulates growth von Franklin, Aaron, Salgueiro, Vivian C., Layton, Abigail J., Sullivan, Rudi, Mize, Todd, Vázquez-Iniesta, Lucía, Benedict, Samuel T., Gurcha, Sudagar S., Anso, Itxaso, Besra, Gurdyal S., Banzhaf, Manuel, Lovering, Andrew L., Williams, Spencer J., Guerin, Marcelo E., Scott, Nichollas E., Prados-Rosales, Rafael, Lowe, Elisabeth C., Moynihan, Patrick J.

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Structure of the priming arabinosyltransferase AftA required for AG biosynthesis of Mycobacterium tuberculosis von Gong, Yicheng, Wei, Chuancun, Wang, Jun, Mu, Nengjiang, Lu, Qinhong, Wu, Chengyao, Yan, Ning, Yang, Huifang, Zhao, Yao, Yang, Xiuna, Gurcha, Sudagar S, Veerapen, Natacha, Batt, Sarah M, Hao, Zhiqiang, Da, Lintai, Besra, Gurdyal S, Rao, Zihe, Zhang, Lu

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Mycolic acid modification by the mmaA4 gene of M. tuberculosis modulates IL-12 production von Dao, Dee N, Sweeney, Kari, Hsu, Tsungda, Gurcha, Sudagar S, Nascimento, Ivan P, Roshevsky, Dan, Besra, Gurdyal S, Chan, John, Porcelli, Steven A, Jacobs, William R

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Biochemical and structural characterization of mycobacterial aspartyl-tRNA synthetase AspS, a promising TB drug target von Gurcha, Sudagar S, Usha, Veeraraghavan, Cox, Jonathan A G, Fütterer, Klaus, Abrahams, Katherine A, Bhatt, Apoorva, Alderwick, Luke J, Reynolds, Robert C, Loman, Nicholas J, Nataraj, VijayaShankar, Alemparte, Carlos, Barros, David, Lloyd, Adrian J, Ballell, Lluis, Hobrath, Judith V, Besra, Gurdyal S

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Keto-mycolic acid-dependent pellicle formation confers tolerance to drug-sensitive Mycobacterium tuberculosis von Sambandan, Dhinakaran, Dao, Dee N, Weinrick, Brian C, Vilchèze, Catherine, Gurcha, Sudagar S, Ojha, Anil, Kremer, Laurent, Besra, Gurdyal S, Hatfull, Graham F, Jacobs, Jr, William R

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Identification of novel Mt-Guab2 inhibitor series active against M. tuberculosis von Usha, Veeraraghavan, Hobrath, Judith V, Gurcha, Sudagar S, Reynolds, Robert C, Besra, Gurdyal S

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Ppm1-encoded polyprenyl monophosphomannose synthase activity is essential for lipoglycan synthesis and survival in mycobacteria von Rana, Amrita K, Singh, Albel, Gurcha, Sudagar S, Cox, Liam R, Bhatt, Apoorva, Besra, Gurdyal S

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Deletion of kasB in Mycobacterium tuberculosis causes loss of acid-fastness and subclinical latent tuberculosis in immunocompetent mice von Bhatt, Apoorva, Fujiwara, Nagatoshi, Bhatt, Kiranmai, Gurcha, Sudagar S, Kremer, Laurent, Chen, Bing, Chan, John, Porcelli, Steven A, Kobayashi, Kazuo, Besra, Gurdyal S, Jacobs, William R. Jr

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3‐Ketosteroid 9α‐hydroxylase is an essential factor in the pathogenesis of Mycobacterium tuberculosis von Hu, Yanmin, Van Der Geize, Robert, Besra, Gurdyal S., Gurcha, Sudagar S., Liu, Alexander, Rohde, Manfred, Singh, Mahavir, Coates, Anthony

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Structural analysis of phosphoribosyltransferase-mediated cell wall precursor synthesis in Mycobacterium tuberculosis von Gao, Shan, Wu, Fangyu, Gurcha, Sudagar S., Batt, Sarah M., Besra, Gurdyal S., Rao, Zihe, Zhang, Lu

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Cryo-EM snapshots of mycobacterial arabinosyltransferase complex EmbB2-AcpM2 von Zhang, Lu, Zhao, Yao, Gao, Ruogu, Li, Jun, Yang, Xiuna, Gao, Yan, Zhao, Wei, Gurcha, Sudagar S., Veerapen, Natacha, Batt, Sarah M., Besra, Kajelle Kaur, Xu, Wenqing, Bi, Lijun, Zhang, Xian’en, Guddat, Luke W., Yang, Haitao, Wang, Quan, Besra, Gurdyal S., Rao, Zihe

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Zebrafish embryo screen for mycobacterial genes involved in the initiation of granuloma formation reveals a newly identified ESX-1 component von Stoop, Esther J M, Schipper, Tim, Rosendahl Huber, Sietske K, Nezhinsky, Alexander E, Verbeek, Fons J, Gurcha, Sudagar S, Besra, Gurdyal S, Vandenbroucke-Grauls, Christina M J E, Bitter, Wilbert, van der Sar, Astrid M

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Modular Approach to Triazole-Linked 1,6-α-d-Oligomannosides to the Discovery of Inhibitors of Mycobacterium tuberculosis Cell Wall Synthetase von Lo Conte, Mauro, Marra, Alberto, Chambery, Angela, Gurcha, Sudagar S, Besra, Gurdyal S, Dondoni, Alessandro

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Role of Phosphatidylinositol Mannosides in the Interaction between Mycobacteria and DC-SIGN von Driessen, Nicole N, Ummels, Roy, Maaskant, Janneke J, Gurcha, Sudagar S, Besra, Gurdyal S, Ainge, Gary D, Larsen, David S, Painter, Gavin F, Vandenbroucke-Grauls, Christina M.J.E, Geurtsen, Jeroen, Appelmelk, Ben J

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Fluorescent mannosides serve as acceptor substrates for glycosyltransferase and sugar-1-phosphate transferase activities in Euglena gracilis membranes von Ivanova, Irina M., Nepogodiev, Sergey A., Saalbach, Gerhard, O'Neill, Ellis C., Urbaniak, Michael D., Ferguson, Michael A.J., Gurcha, Sudagar S., Besra, Gurdyal S., Field, Robert A.

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The evaluation of forty-three plant species for in vitro antimycobacterial activities; isolation of active constituents from Psoralea corylifolia and Sanguinaria canadensis von Newton, Sandra M, Lau, Clara, Gurcha, Sudagar S, Besra, Gurdyal S, Wright, Colin W

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