Fatal Seronegative Ehrlichiosis in a Patient with HIV Infection von Paddock, Christopher D, Suchard, David P, Grumbach, Kevin L, Hadley, W. Keith, Kerschmann, Russell L, Abbey, Nancy W, Dawson, Jaqueline E, Anderson, Burt E, Sims, Kimetha G, Dumler, J. Stephen, Herndier, Brian G

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Brief report: fatal seronegative ehrlichiosis in a patient with HIV infection von Paddock, C D, Suchard, D P, Grumbach, K L, Hadley, W K, Kerschmann, R L, Abbey, N W, Dawson, J E, Anderson, B E, Sims, K G, Dumler, J S

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Vaccine Safety Surveillance Using Routinely Collected Healthcare Data—An Empirical Evaluation of Epidemiological Designs von Schuemie, Martijn J., Arshad, Faaizah, Pratt, Nicole, Nyberg, Fredrik, Alshammari, Thamir M, Hripcsak, George, Ryan, Patrick, Prieto-Alhambra, Daniel, Lai, Lana Y. H., Li, Xintong, Fortin, Stephen, Minty, Evan, Suchard, Marc A.

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Emergence of an early SARS-CoV-2 epidemic in the United States von Zeller, Mark, Gangavarapu, Karthik, Anderson, Catelyn, Smither, Allison R., Vanchiere, John A., Rose, Rebecca, Snyder, Daniel J., Dudas, Gytis, Watts, Alexander, Matteson, Nathaniel L., Robles-Sikisaka, Refugio, Marshall, Maximilian, Feehan, Amy K., Sabino-Santos, Gilberto, Bell-Kareem, Antoinette R., Hughes, Laura D., Alkuzweny, Manar, Snarski, Patricia, Garcia-Diaz, Julia, Scott, Rona S., Melnik, Lilia I., Klitting, Raphaëlle, McGraw, Michelle, Belda-Ferre, Pedro, DeHoff, Peter, Sathe, Shashank, Marotz, Clarisse, Grubaugh, Nathan D., Nolan, David J., Drouin, Arnaud C., Genemaras, Kaylynn J., Chao, Karissa, Topol, Sarah, Spencer, Emily, Nicholson, Laura, Aigner, Stefan, Yeo, Gene W., Farnaes, Lauge, Hobbs, Charlotte A., Laurent, Louise C., Knight, Rob, Hodcroft, Emma B., Khan, Kamran, Fusco, Dahlene N., Cooper, Vaughn S., Lemey, Phillipe, Gardner, Lauren, Lamers, Susanna L., Kamil, Jeremy P., Garry, Robert F., Suchard, Marc A., Andersen, Kristian G.

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Genomic assessment of invasion dynamics of SARS-CoV-2 Omicron BA.1 von Tsui, Joseph L-H, McCrone, John T, Lambert, Ben, Bajaj, Sumali, Inward, Rhys P D, Bosetti, Paolo, Pena, Rosario Evans, Tegally, Houriiyah, Hill, Verity, Zarebski, Alexander E, Peacock, Thomas P, Liu, Luyang, Wu, Neo, Davis, Megan, Bogoch, Isaac I, Khan, Kamran, Kall, Meaghan, Abdul Aziz, Nurin Iwani Binti, Colquhoun, Rachel, O'Toole, Áine, Jackson, Ben, Dasgupta, Abhishek, Wilkinson, Eduan, de Oliveira, Tulio, Connor, Thomas R, Loman, Nicholas J, Colizza, Vittoria, Fraser, Christophe, Volz, Erik, Ji, Xiang, Gutierrez, Bernardo, Chand, Meera, Dellicour, Simon, Cauchemez, Simon, Raghwani, Jayna, Suchard, Marc A, Lemey, Philippe, Rambaut, Andrew, Pybus, Oliver G, Kraemer, Moritz U G

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Genomic and epidemiological monitoring of yellow fever virus transmission potential von Faria, N R, Kraemer, M U G, Hill, S C, Goes de Jesus, J, Aguiar, R S, Iani, F C M, Xavier, J, Quick, J, du Plessis, L, Dellicour, S, Thézé, J, Carvalho, R D O, Baele, G, Wu, C-H, Silveira, P P, Arruda, M B, Pereira, M A, Pereira, G C, Lourenço, J, Obolski, U, Abade, L, Vasylyeva, T I, Giovanetti, M, Yi, D, Weiss, D J, Wint, G R W, Shearer, F M, Funk, S, Nikolay, B, Fonseca, V, Adelino, T E R, Oliveira, M A A, Silva, M V F, Sacchetto, L, Figueiredo, P O, Rezende, I M, Mello, E M, Said, R F C, Santos, D A, Ferraz, M L, Brito, M G, Santana, L F, Menezes, M T, Brindeiro, R M, Tanuri, A, Dos Santos, F C P, Cunha, M S, Nogueira, J S, Rocco, I M, da Costa, A C, Komninakis, S C V, Azevedo, V, Chieppe, A O, Araujo, E S M, Mendonça, M C L, Dos Santos, C C, Dos Santos, C D, Mares-Guia, A M, Nogueira, R M R, Sequeira, P C, Abreu, R G, Garcia, M H O, Abreu, A L, Okumoto, O, Kroon, E G, de Albuquerque, C F C, Lewandowski, K, Pullan, S T, Carroll, M, de Oliveira, T, Sabino, E C, Souza, R P, Suchard, M A, Lemey, P, Trindade, G S, Drumond, B P, Filippis, A M B, Loman, N J, Cauchemez, S, Alcantara, L C J, Pybus, O G

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Seek COVER: using a disease proxy to rapidly develop and validate a personalized risk calculator for COVID-19 outcomes in an international network von Williams, Ross D, Markus, Aniek F, Yang, Cynthia, Duarte-Salles, Talita, DuVall, Scott L, Falconer, Thomas, Jonnagaddala, Jitendra, Kim, Chungsoo, Rho, Yeunsook, Williams, Andrew E, Machado, Amanda Alberga, An, Min Ho, Aragón, María, Areia, Carlos, Burn, Edward, Choi, Young Hwa, Drakos, Iannis, Abrahão, Maria Tereza Fernandes, Fernández-Bertolín, Sergio, Hripcsak, George, Kaas-Hansen, Benjamin Skov, Kandukuri, Prasanna L, Kors, Jan A, Kostka, Kristin, Liaw, Siaw-Teng, Lynch, Kristine E, Machnicki, Gerardo, Matheny, Michael E, Morales, Daniel, Nyberg, Fredrik, Park, Rae Woong, Prats-Uribe, Albert, Pratt, Nicole, Rao, Gowtham, Reich, Christian G, Rivera, Marcela, Seinen, Tom, Shoaibi, Azza, Spotnitz, Matthew E, Steyerberg, Ewout W, Suchard, Marc A, You, Seng Chan, Zhang, Lin, Zhou, Lili, Ryan, Patrick B, Prieto-Alhambra, Daniel, Reps, Jenna M, Rijnbeek, Peter R

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Risk of hydroxychloroquine alone and in combination with azithromycin in the treatment of rheumatoid arthritis: a multinational, retrospective study von Lane, Jennifer C E, Weaver, James, Kostka, Kristin, Duarte-Salles, Talita, Abrahao, Maria Tereza F, Alghoul, Heba, Alser, Osaid, Alshammari, Thamir M, Biedermann, Patricia, Banda, Juan M, Burn, Edward, Casajust, Paula, Conover, Mitchell M, Culhane, Aedin C, Davydov, Alexander, DuVall, Scott L, Dymshyts, Dmitry, Fernandez-Bertolin, Sergio, Fišter, Kristina, Hardin, Jill, Hester, Laura, Hripcsak, George, Kaas-Hansen, Benjamin Skov, Kent, Seamus, Khosla, Sajan, Kolovos, Spyros, Lambert, Christophe G, van der Lei, Johan, Lynch, Kristine E, Makadia, Rupa, Margulis, Andrea V, Matheny, Michael E, Mehta, Paras, Morales, Daniel R, Morgan-Stewart, Henry, Mosseveld, Mees, Newby, Danielle, Nyberg, Fredrik, Ostropolets, Anna, Park, Rae Woong, Prats-Uribe, Albert, Rao, Gowtham A, Reich, Christian, Reps, Jenna, Rijnbeek, Peter, Sathappan, Selva Muthu Kumaran, Schuemie, Martijn, Seager, Sarah, Sena, Anthony G, Shoaibi, Azza, Spotnitz, Matthew, Suchard, Marc A, Torre, Carmen O, Vizcaya, David, Wen, Haini, de Wilde, Marcel, Xie, Junqing, You, Seng Chan, Zhang, Lin, Zhuk, Oleg, Ryan, Patrick, Prieto-Alhambra, Daniel

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Molecular Evolution and Mosaicism of Leptospiral Outer Membrane Proteins Involves Horizontal DNA Transfer von HAAKE, David A, SUCHARD, Marc A, KELLEY, Melissa M, DUNDOO, Manjula, ALT, David P, ZUERNER, Richard L

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Implementation of the COVID-19 Vulnerability Index Across an International Network of Health Care Data Sets: Collaborative External Validation Study von Reps, Jenna M., Kim, Chungsoo, Williams, Ross D., Markus, Aniek F., Yang, Cynthia, Duarte-Salles, Talita, Falconer, Thomas, Jonnagaddala, Jitendra, Williams, Andrew, Fernandez-Bertolin, Sergio, DuVall, Scott L., Kostka, Kristin, Rao, Gowtham, Shoaibi, Azza, Ostropolets, Anna, Spotnitz, Matthew E., Zhang, Lin, Casajust, Paula, Steyerberg, Ewout W., Nyberg, Fredrik, Kaas-Hansen, Benjamin Skov, Choi, Young Hwa, Morales, Daniel, Liaw, Siaw-Teng, Abrahao, Maria Tereza Fernandes, Areia, Carlos, Matheny, Michael E., Lynch, Kristine E., Aragon, Maria, Park, Rae Woong, Hripcsak, George, Reich, Christian G., Suchard, Marc A., You, Seng Chan, Ryan, Patrick B., Prieto-Alhambra, Daniel, Rijnbeek, Peter R.

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COVID-19 in patients with autoimmune diseases: characteristics and outcomes in a multinational network of cohorts across three countries von Tan, Eng Hooi, Sena, Anthony G, Prats-Uribe, Albert, You, Seng Chan, Ahmed, Waheed-Ul-Rahman, Kostka, Kristin, Reich, Christian, Duvall, Scott L, Lynch, Kristine E, Matheny, Michael E, Duarte-Salles, Talita, Bertolin, Sergio Fernandez, Hripcsak, George, Natarajan, Karthik, Falconer, Thomas, Spotnitz, Matthew, Ostropolets, Anna, Blacketer, Clair, Alshammari, Thamir M, Alghoul, Heba, Alser, Osaid, Lane, Jennifer C E, Dawoud, Dalia M, Shah, Karishma, Yang, Yue, Zhang, Lin, Areia, Carlos, Golozar, Asieh, Recalde, Martina, Casajust, Paula, Jonnagaddala, Jitendra, Subbian, Vignesh, Vizcaya, David, Lai, Lana Y H, Nyberg, Fredrik, Morales, Daniel R, Posada, Jose D, Shah, Nigam H, Gong, Mengchun, Vivekanantham, Arani, Abend, Aaron, Minty, Evan P, Suchard, Marc, Rijnbeek, Peter, Ryan, Patrick B, Prieto-Alhambra, Daniel

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Abatacept modulates human dendritic cell-stimulated T-cell proliferation and effector function independent of IDO induction von Davis, Patricia M, Nadler, Steven G, Stetsko, Dawn K, Suchard, Suzanne J

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A Physical Map of 30,000 Human Genes von Deloukas, P., Schuler, G. D., Gyapay, G., Beasley, E. M., Soderlund, C., Rodriguez-Tomé, P., Hui, L., Matise, T. C., McKusick, K. B., Beckmann, J. S., Bentolila, S., M.-T. Bihoreau, Birren, B. B., Browne, J., Butler, A., Castle, A. B., Chiannilkulchai, N., Clee, C., Day, P. J. R., Dehejia, A., Dibling, T., Drouot, N., Duprat, S., Fizames, C., Fox, S., Gelling, S., Green, L., Harrison, P., Hocking, R., Holloway, E., Hunt, S., Keil, S., Lijnzaad, P., C. Louis-Dit-Sully, Ma, J., Mendis, A., Miller, J., Morissette, J., Muselet, D., Nusbaum, H. C., Peck, A., Rozen, S., Simon, D., Slonim, D. K., Staples, R., Stein, L. D., Stewart, E. A., Suchard, M. A., Thangarajah, T., Vega-Czarny, N., Webber, C., Wu, X., Hudson, J., Auffray, C., Nomura, N., Sikela, J. M., Polymeropoulous, M. H., James, M. R., Lander, E. S., Hudson, T. J., Myers, R. M., Cox, D. R., Weissenbach, J., Boguski, M. S., Bentley, D. R.

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Global disparities in SARS-CoV-2 genomic surveillance von Brito, AF, Semonva, E, Dudas, G, Hassler, GW, Kalinich, CC, Kraemer, MUG, Ho, J, Houriyah, T, Githinji, G, Agoti, CN, Matkin, LE, Whittaker, C, Bulgarian SARS-CoV-2 sequencing group, Communicable Diseases Genomics Network (Australia and New Zealand), COVID-19 Impact Project, Danish Covid-19 Genome Consortium#, Fiocruz COVID-19 Genomic Surveillance Network, GISAID core curation team, Network for Genomic Surveillance in South Africa (NGS-SA), Swiss SARS-CoV-2 Sequencing Consortium, Howden, BP, Sintchenko, V, Zuckerman, NS, Mor, O, Blankenship, HM, De Oliveira, T, Lin, RTP, Siqueira, MM, Resende, PC, Vasconcelos, TR, Spilki, FR, Aguiar, RS, Alexiev, I, Ivanov, IN, Philipova, I, Carrington, CVF, Sahadeo, NSD, Branda, B, Gurry, C, Maurer-Stroh, S, Naidoo, D, Von Eije, KJ, Perkins, MD, Von Kerkhove, M, Hill, SC, Sabino, EC, Pybus, OG, Dye, C, Bhatt, S, Flaxman, S, Suchard, MA, Grubaugh, ND, Baele, G, Faria, NM

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Discussion: An estimate of the science-wise false discovery rate and application to the top medical literature von Schuemie, Martijn J, Ryan, Patrick B, Suchard, Marc A, Shahn, Zach, Madigan, David

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Emergence of an early SARS-CoV-2 epidemic in the United States von Zeller, Mark, Gangavarapu, Karthik, Anderson, Catelyn, Smither, Allison R, Vanchiere, John A, Rose, Rebecca, Snyder, Daniel J, Dudas, Gytis, Watts, Alexander, Matteson, Nathaniel L, Robles-Sikisaka, Refugio, Marshall, Maximilian, Feehan, Amy K, Sabino-Santos, Gilberto, Bell-Kareem, Antoinette R, Hughes, Laura D, Alkuzweny, Manar, Snarski, Patricia, Garcia-Diaz Jr, Julia, Scott, Rona S, Melnik, Lilia, Klitting, Raphaelle, McGraw, Michelle, Belda-Ferre, Pedro, DeHoff, Peter, Sathe, Shashank, Marotz, Clarisse, Grubaugh, Nathan D, Nolan, David J, Drouin, Arnaud C, Genemaras, Kaylynn J, Chao, Karissa, Topol, Sarah, Spencer, Emily, Nicholson, Laura, Aigner, Stefan, Yeo, Gene W, Farnaes, Lauge, Hobbs, Charlotte A, Laurent, Louise C, Knight, Rob, Hodcroft, Emma B, Khan, Kamran, Fusco, Dahlene N, Cooper, Vaughn S, Lemey, Phillipe, Gardner, Lauren, Lamers, Susanna L, Kamil, Jeremy P, Garry, Robert F, Suchard, Marc A, Andersen, Kristian G

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Virus genomes reveal factors that spread and sustained the Ebola epidemic von Dudas, G, Carvalho, LM, Bedford, T, Tatem, AJ, Baele, G, Faria, NR, Park, DJ, Ladner, JT, Arias, A, Asogun, D, Bielejec, F, Caddy, SL, Cotten, M, D'Ambrozio, J, Dellicour, S, Di Caro, A, Diclaro, JW, Duraffour, S, Elmore, MJ, Iii, LSF, Faye, O, Gilbert, ML, Gevao, SM, Gire, S, Gladden-Young, A, Gnirke, A, Goba, A, Grant, DS, Haagmans, BL, Hiscox, JA, Jah, U, Kugelman, JR, Liu, D, Lu, J, Malboeuf, CM, Mate, S, Matthews, DA, Matranga, CB, Meredith, LW, Qu, J, Quick, J, Pas, SD, Phan, MVT, Pollakis, G, Reusken, CB, Sanchez-Lockhart, M, Schaffner, SF, Schieffelin, JS, Sealfon, RS, Simon-Loriere, E, Smits, SL, Stoecker, K, Thorne, L, Tobin, EA, Vandi, MA, Watson, SJ, West, K, Whitmer, S, Wiley, MR, Winnicki, SM, Wohl, S, Wolfel, R, Yozwiak, NL, Andersen, KG, Blyden, SO, Bolay, F, Carroll, MW, Dahn, B, Diallo, B, Formenty, P, Fraser, C, Gao, GF, Garry, RF, Goodfellow, I, Gnther, S, Happi, CT, Holmes, EC, Kargbo, B, Keita, S, Kellam, P, Koopmans, MPG, Kuhn, JH, Loman, NJ, Magassouba, N, Naidoo, D, Nichol, ST, Nyenswah, T, Palacios, G, Pybus, OG, Sabeti, PC, Sall, A, Stroher, U, Wurie, I, Suchard, MA, Lemey, P, Rambaut, A

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Discovery and Development of 5-[(5S,9R)-9- (4-Cyanophenyl)-3-(3,5-dichlorophenyl)-1- methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]non- 7-yl-methyl]-3-thiophenecarboxylic Acid (BMS-587101... von Potin, Dominique, Launay, Michele, Monatlik, Francoise, Malabre, Patrice, Fabreguettes, Maud, Fouquet, Andre, Maillet, Magali, Nicolai, Eric, Dorgeret, Loïc, Chevallier, François, Besse, Dominique, Dufort, Monique, Caussade, François, Ahmad, Syed Z, Stetsko, Dawn K, Skala, Stacey, Davis, Patricia M, Balimane, Praveen, Patel, Karishma, Yang, Zheng, Marathe, Punit, Postelneck, Jennifer, Townsend, Robert M, Goldfarb, Valentina, Sheriff, Steven, Einspahr, Howard, Kish, Kevin, Malley, Mary F, DiMarco, John D, Gougoutas, Jack Z, Kadiyala, Pathanjali, Cheney, Daniel L, Tejwani, Ravindra W, Murphy, Denette K, Mcintyre, Kim W, Yang, Xiaoxia, Chao, Sam, Leith, Leslie, Xiao, Zili, Mathur, Arvind, Chen, Bang-Chi, Wu, Daugh-Rurng, Traeger, Sarah C, McKinnon, Murray, Barrish, Joel C, Robl, Jeffrey A, Iwanowicz, Edwin J, Suchard, Suzanne J, Dhar, T. G. Murali

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Ancient DNA analyses exclude humans as the driving force behind late Pleistocene musk ox (Ovibos moschatus) population dynamics von Campos, Paula F, Willerslev, Eske, Sher, Andrei, Orlando, Ludovic, Axelsson, Erik, Tikhonov, Alexei, Aaris-Sorensen, Kim, Greenwood, Alex D, Kahlke, Ralf-Dietrich, Kosintsev, Pavel, Krakhmalnaya, Tatiana, Kuznetsova, Tatyana, Lemey, Philippe, MacPhee, Ross, Norris, Christopher A, Shepherd, Kieran, Suchard, Marc A, Zazula, Grant D, Shapiro, Beth, Gilbert, M. Thomas P

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Visualizing Dynamics of Charges and Strings in (2+1)D Lattice Gauge Theories von Cochran, Tyler A, Jobst, Bernhard, Lensky, Yuri D, Gyawali, Gaurav, Eassa, Norhan, Will, Melissa, Acharya, Rajeev, Beni, Laleh Aghababaie, Andersen, Trond I, Arute, Frank, Arya, Kunal, Atalaya, Juan, Babbush, Ryan, Bardin, Joseph C, Bengtsson, Andreas, Bilmes, Alexander, Bovaird, Jenna, Browne, David A, Burger, Tim, Bushnell, Nicholas, Claes, Jahan, Cogan, Josh, Conner, Paul, Courtney, William, Das, Sayan, Demura, Sean, Di Paolo, Agustin, Drozdov, Ilya, Elbag, Aviv Moshe, Elzouka, Mahmoud, Burgos, Leslie Flores, Fowler, Austin G, Ganjam, Suhas, Giang, William, Gilboa, Dar, Gosula, Raja, Hansen, Monica, Higgott, Oscar, Hilton, Jeremy, Huang, Hsin-Yuan, Huff, Ashley, Jeffrey, Evan, Jiang, Zhang, Jones, Cody, Joshi, Chaitali, Juhas, Pavol, Kafri, Dvir, Karamlou, Amir H, Khaire, Trupti, Kobrin, Bryce, Korotkov, Alexander N, Kostritsa, Fedor, Landhuis, David, Langley, Brandon W, Lau, Kim-Ming, Ledford, Justin, Lester, Brian J, Guevel, Loïck Le, Li, Wing Yan, Lunt, Aaron, Madhuk, Sid, Mandrà, Salvatore, McClean, Jarrod R, Meeks, Seneca, Megrant, Anthony, Molavi, Reza, Newman, Michael, Nguyen, Anthony, Nguyen, Murray, Ni, Chia-Hung, Ottosson, Kristoffer, Pizzuto, Alex, Quintana, Chris, Ramachandran, Ganesh, Reagor, Matthew J, Roberts, Gabrielle, Sankaragomathi, Kannan, Schurkus, Henry F, Shvarts, Vladimir, Smith, W. Clarke, Springer, Sofia, Sterling, George, Suchard, Jordan, Szasz, Aaron, Thor, Douglas, Torunbalci, M. Mert, Vidal, Guifre, Wang, Shannon X, Wong, Kristi, Woo, Bryan W. K, Xing, Cheng, Ying, Bicheng, Yosri, Noureldin, Young, Grayson, Zhang, Yaxing, Zhu, Ningfeng, Zobris, Nicholas, Kelly, Julian, Neven, Hartmut, Roushan, Pedram

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