Caspases in Cell Death, Inflammation, and Pyroptosis von Kesavardhana, Sannula, Malireddi, R.K. Subbarao, Kanneganti, Thirumala-Devi

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ZBP1 and TAK1: Master Regulators of NLRP3 Inflammasome/Pyroptosis, Apoptosis, and Necroptosis (PAN-optosis) von Malireddi, R K Subbarao, Kesavardhana, Sannula, Kanneganti, Thirumala-Devi

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The PANoptosome: A Deadly Protein Complex Driving Pyroptosis, Apoptosis, and Necroptosis (PANoptosis) von Samir, Parimal, Malireddi, R K Subbarao, Kanneganti, Thirumala-Devi

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The TWIK2 Potassium Efflux Channel in Macrophages Mediates NLRP3 Inflammasome-Induced Inflammation von Di, Anke, Xiong, Shiqin, Ye, Zhiming, Malireddi, R.K. Subbarao, Kometani, Satoshi, Zhong, Ming, Mittal, Manish, Hong, Zhigang, Kanneganti, Thirumala-Devi, Rehman, Jalees, Malik, Asrar B.

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Impaired NLRP3 inflammasome activation/pyroptosis leads to robust inflammatory cell death via caspase-8/RIPK3 during coronavirus infection von Zheng, Min, Williams, Evan Peter, Malireddi, R.K. Subbarao, Karki, Rajendra, Banoth, Balaji, Burton, Amanda, Webby, Richard, Channappanavar, Rudragouda, Jonsson, Colleen Beth, Kanneganti, Thirumala-Devi

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Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes von Karki, Rajendra, Sharma, Bhesh Raj, Tuladhar, Shraddha, Williams, Evan Peter, Zalduondo, Lillian, Samir, Parimal, Zheng, Min, Sundaram, Balamurugan, Banoth, Balaji, Malireddi, R.K. Subbarao, Schreiner, Patrick, Neale, Geoffrey, Vogel, Peter, Webby, Richard, Jonsson, Colleen Beth, Kanneganti, Thirumala-Devi

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SYK-CARD9 Signaling Axis Promotes Gut Fungi-Mediated Inflammasome Activation to Restrict Colitis and Colon Cancer von Malik, Ankit, Sharma, Deepika, Malireddi, R.K. Subbarao, Guy, Clifford S., Chang, Ti-Cheng, Olsen, Scott R., Neale, Geoffrey, Vogel, Peter, Kanneganti, Thirumala-Devi

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The NOD-Like Receptor NLRP12 Attenuates Colon Inflammation and Tumorigenesis von Zaki, Md. Hasan, Vogel, Peter, Malireddi, R.K. Subbarao, Body-Malapel, Mathilde, Anand, Paras K., Bertin, John, Green, Douglas R., Lamkanfi, Mohamed, Kanneganti, Thirumala-Devi

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Molecular characterization of LC3-associated phagocytosis reveals distinct roles for Rubicon, NOX2 and autophagy proteins von Martinez, Jennifer, Malireddi, R K Subbarao, Lu, Qun, Cunha, Larissa Dias, Pelletier, Stephane, Gingras, Sebastien, Orchard, Robert, Guan, Jun-Lin, Tan, Haiyan, Peng, Junmin, Kanneganti, Thirumala-Devi, Virgin, Herbert W, Green, Douglas R

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NLRP6 negatively regulates innate immunity and host defence against bacterial pathogens von Anand, Paras K., Malireddi, R. K. Subbarao, Lukens, John R., Vogel, Peter, Bertin, John, Lamkanfi, Mohamed, Kanneganti, Thirumala-Devi

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The Zα2 domain of ZBP1 is a molecular switch regulating influenza-induced PANoptosis and perinatal lethality during development von Kesavardhana, Sannula, Malireddi, R. K. Subbarao, Burton, Amanda R., Porter, Shaina N., Vogel, Peter, Pruett-Miller, Shondra M., Kanneganti, Thirumala-Devi

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The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infection von Man, Si Ming, Karki, Rajendra, Malireddi, R K Subbarao, Neale, Geoffrey, Vogel, Peter, Yamamoto, Masahiro, Lamkanfi, Mohamed, Kanneganti, Thirumala-Devi

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Role of inflammasomes/pyroptosis and PANoptosis during fungal infection von Briard, Benoit, Malireddi, R K Subbarao, Kanneganti, Thirumala-Devi

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Osteoclast fusion and bone loss are restricted by interferon inducible guanylate binding proteins von Place, David E., Malireddi, R. K. Subbarao, Kim, Jieun, Vogel, Peter, Yamamoto, Masahiro, Kanneganti, Thirumala-Devi

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DDX3X acts as a live-or-die checkpoint in stressed cells by regulating NLRP3 inflammasome von Samir, Parimal, Kesavardhana, Sannula, Patmore, Deanna M., Gingras, Sebastien, Malireddi, R. K. Subbarao, Karki, Rajendra, Guy, Clifford S., Briard, Benoit, Place, David E., Bhattacharya, Anannya, Sharma, Bhesh Raj, Nourse, Amanda, King, Sharon V., Pitre, Aaron, Burton, Amanda R., Pelletier, Stephane, Gilbertson, Richard J., Kanneganti, Thirumala-Devi

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Innate immune priming in the absence of TAK1 drives RIPK1 kinase activity-independent pyroptosis, apoptosis, necroptosis, and inflammatory disease von Malireddi, R K Subbarao, Gurung, Prajwal, Kesavardhana, Sannula, Samir, Parimal, Burton, Amanda, Mummareddy, Harisankeerth, Vogel, Peter, Pelletier, Stephane, Burgula, Sandeepta, Kanneganti, Thirumala-Devi

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TAK1 restricts spontaneous NLRP3 activation and cell death to control myeloid proliferation von Malireddi, R K Subbarao, Gurung, Prajwal, Mavuluri, Jayadev, Dasari, Tejasvi Krishna, Klco, Jeffery M, Chi, Hongbo, Kanneganti, Thirumala-Devi

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IRF8 Regulates Transcription of Naips for NLRC4 Inflammasome Activation von Karki, Rajendra, Lee, Ein, Place, David, Samir, Parimal, Mavuluri, Jayadev, Sharma, Bhesh Raj, Balakrishnan, Arjun, Malireddi, R.K. Subbarao, Geiger, Rechel, Zhu, Qifan, Neale, Geoffrey, Kanneganti, Thirumala-Devi

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ZBP1/DAI ubiquitination and sensing of influenza vRNPs activate programmed cell death von Kesavardhana, Sannula, Kuriakose, Teneema, Guy, Clifford S, Samir, Parimal, Malireddi, R K Subbarao, Mishra, Ashutosh, Kanneganti, Thirumala-Devi

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ADAR1 restricts ZBP1-mediated immune response and PANoptosis to promote tumorigenesis von Karki, Rajendra, Sundaram, Balamurugan, Sharma, Bhesh Raj, Lee, SangJoon, Malireddi, R.K. Subbarao, Nguyen, Lam Nhat, Christgen, Shelbi, Zheng, Min, Wang, Yaqiu, Samir, Parimal, Neale, Geoffrey, Vogel, Peter, Kanneganti, Thirumala-Devi

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