Simultaneous CK2/TNIK/DYRK1 inhibition by 108600 suppresses triple negative breast cancer stem cells and chemotherapy-resistant disease von Sato, Katsutoshi, Padgaonkar, Amol A., Baker, Stacey J., Cosenza, Stephen C., Rechkoblit, Olga, Subbaiah, D. R. C. Venkata, Domingo-Domenech, Josep, Bartkowski, Alison, Port, Elisa R., Aggarwal, Aneel K., Ramana Reddy, M. V., Irie, Hanna Y., Reddy, E. Premkumar

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Discovery of 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one (7ao) as a potent selective inhibitor of Polo like kinase 2 (PLK2) von Reddy, M.V. Ramana, Akula, Balireddy, Jatiani, Shashidhar, Vasquez-Del Carpio, Rodrigo, Billa, Vinay K., Mallireddigari, Muralidhar R., Cosenza, Stephen C., Venkata Subbaiah, D.R.C., Bharathi, E. Vijaya, Pallela, Venkat R., Ramkumar, Poornima, Jain, Rinku, Aggarwal, Aneel K., Reddy, E. Premkumar

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Hydrothiolation of benzyl mercaptan to arylacetylene: application to the synthesis of (E) and (Z)-isomers of ON 01910·Na (Rigosertib®), a phase III clinical stage anti-cancer agent... von Pallela, Venkat R, Mallireddigari, Muralidhar R, Cosenza, Stephen C, Akula, Balaiah, Subbaiah, D R C Venkata, Reddy, E Premkumar, Reddy, M V Ramana

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Discovery of 8‑Cyclopentyl-2-[4-(4-methyl-piperazin-1-yl)-phenylamino]-7-oxo-7,8-dihydro-pyrido[2,3‑d]pyrimidine-6-carbonitrile (7x) as a Potent Inhibitor of Cyclin-Dependent Kinas... von Reddy, M. V. Ramana, Akula, Balireddy, Cosenza, Stephen C, Athuluridivakar, Saikrishna, Mallireddigari, Muralidhar R, Pallela, Venkat R, Billa, Vinay K, Subbaiah, D. R. C. Venkata, Bharathi, E. Vijaya, Vasquez-Del Carpio, Rodrigo, Padgaonkar, Amol, Baker, Stacey J, Reddy, E. Premkumar

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Biological evaluation of sulfone derivatives as anti-inflammatory and tumor cells growth inhibitory agents von Fang, Shih-Hua, Padmavathi, V., Rao, Yerra Koteswara, Venkata Subbaiah, D.R.C., Thriveni, P., Geethangili, Madamanchi, Padmaja, A., Tzeng, Yew-Min

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(Z)-1-Aryl-3-arylamino-2-propen-1-ones, Highly Active Stimulators of Tubulin Polymerization: Synthesis, Structure–Activity Relationship (SAR), Tubulin Polymerization, and Cell Grow... von Reddy, M. V. Ramana, Akula, Balaiah, Cosenza, Stephen C, Lee, Clement M, Mallireddigari, Muralidhar R, Pallela, Venkat R, Subbaiah, D. R. C. Venkata, Udofa, Andrew, Reddy, E. Premkumar

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Design, Synthesis, and Biological Evaluation of (E)‑N‑Aryl-2-arylethenesulfonamide Analogues as Potent and Orally Bioavailable Microtubule-Targeted Anticancer Agents von Reddy, M. V. Ramana, Mallireddigari, Muralidhar R, Pallela, Venkat R, Cosenza, Stephen C, Billa, Vinay K, Akula, Balaiah, Subbaiah, D. R. C. Venkata, Bharathi, E. Vijaya, Padgaonkar, Amol, Lv, Hua, Gallo, James M, Reddy, E. Premkumar

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Bischalcones—synthons for a new class of bis(heterocycles) von Padmavathi, Venkatapuram, Reddy, B. Jagan Mohan, Subbaiah, D. R. C. Venkata

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Design, Synthesis and Biological Evaluation of (E)-N-Aryl-2-arylethene-sulfonamide Analogues as Potent and Orally Bioavailable Microtubule-targeted Anticancer Agents von Ramana Reddy, M. V., Mallireddigari, Muralidhar R., Pallela, Venkat R., Cosenza, Stephen C., Billa, Vinay K., Akula, Balaiah, Venkata Subbaiah, D. R. C., Bharathi, E. Vijaya, Padgaonkar, Amol, Lv, Hua, Gallo, James M., Reddy, E. Premkumar

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Hydrothiolation of benzyl mercaptan to arylacetylene: application to the synthesis of (E) and (Z)-isomers of ON 01910·Na (Rigosertib®), a phase III clinical stage anti-cancer agent... von Pallela, Venkat R, Mallireddigari, Muralidhar R, Cosenza, Stephen C, Akula, Balaiah, Subbaiah, D. R. C. Venkata, Reddy, E. Premkumar, Reddy, M. V. Ramana

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Michael adducts-synthons for pyrazolidinediones, isoxazolidinediones, pyrimidinetriones, and thioxopyrimidinediones von Padmavathi, V., Subbaiah, D. R. C. Venkata, Sarma, M. Rajagopala, Balaiah, A.

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ChemInform Abstract: Enantioselective First Total Syntheses of 2-(Formylamino)trachyopsane and ent-2-(Isocyano)trachyopsane via a Biomimetic Approach von Srikrishna, A., Ravi, G., Subbaiah, D. R. C. Venkata

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Michael Adducts - Synthons for a New Class of 1,4-Dispirocyclohexane Derivatives von Padmavathi, V., Reddy, B. Jagan Mohan, Subbaiah, D. R. C. Venkata, Padmaja, A.

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Michael Addition of Active Methylene Compounds to α,β-Unsaturated Sulfones von Padmavathi, V., Subbaiah, D. R. C. Venkata, Balaiah, A., Reddy, B. Chandra Obula, Padmaja, A.

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Bischalcones - Synthons for a New Class of Bis(heterocycles) von Padmavathi, Venkatapuram, Reddy, B. Jagan Mohan, Subbaiah, D. R. C. Venkata

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Michael Adducts-Synthons for Pyrazolidinediones, Isoxazolidinediones, Pyrimidinetriones, and Thioxopyrimidinediones von Padmavathi, V., Subbaiah, D. R. C. Venkata, Sarma, M. Rajagopala, Balaiah, A.

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Sulfonyl Acetic Acids - Source for Substituted 2-Oxazolines von Padmavathi, V., Reddy, B. Chandra Obula, Subbaiah, D. R. C. Venkata, Padmaja, A.

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