Recurrent mutations refine prognosis in chronic lymphocytic leukemia von Baliakas, P, Hadzidimitriou, A, Sutton, L-A, Rossi, D, Minga, E, Villamor, N, Larrayoz, M, Kminkova, J, Agathangelidis, A, Davis, Z, Tausch, E, Stalika, E, Kantorova, B, Mansouri, L, Scarfò, L, Cortese, D, Navrkalova, V, Rose-Zerilli, M J J, Smedby, K E, Juliusson, G, Anagnostopoulos, A, Makris, A M, Navarro, A, Delgado, J, Oscier, D, Belessi, C, Stilgenbauer, S, Ghia, P, Pospisilova, S, Gaidano, G, Campo, E, Strefford, J C, Stamatopoulos, K, Rosenquist, R

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Whole-exome sequencing in splenic marginal zone lymphoma reveals mutations in genes involved in marginal zone differentiation von Martínez, N, Almaraz, C, Vaqué, J P, Varela, I, Derdak, S, Beltran, S, Mollejo, M, Campos-Martin, Y, Agueda, L, Rinaldi, A, Kwee, I, Gut, M, Blanc, J, Oscier, D, Strefford, J C, Martinez-Lopez, J, Salar, A, Sole, F, Rodriguez-Peralto, J L, Diez-Tascón, C, García, J F, Fraga, M, Sebastián, E, Alvés, J, Menárguez, J, González-Carreró, J, Casado, L F, Bayes, M, Bertoni, F, Gut, I, Piris, M A

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13q deletion anatomy and disease progression in patients with chronic lymphocytic leukemia von Parker, H, Rose-Zerilli, M J J, Parker, A, Chaplin, T, Wade, R, Gardiner, A, Griffiths, M, Collins, A, Young, B D, Oscier, D G, Strefford, J C

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Genomic disruption of the histone methyltransferase SETD2 in chronic lymphocytic leukaemia von Parker, H, Rose-Zerilli, M J J, Larrayoz, M, Clifford, R, Edelmann, J, Blakemore, S, Gibson, J, Wang, J, Ljungström, V, Wojdacz, T K, Chaplin, T, Roghanian, A, Davis, Z, Parker, A, Tausch, E, Ntoufa, S, Ramos, S, Robbe, P, Alsolami, R, Steele, A J, Packham, G, Rodríguez-Vicente, A E, Brown, L, McNicholl, F, Forconi, F, Pettitt, A, Hillmen, P, Dyer, M, Cragg, M S, Chelala, C, Oakes, C C, Rosenquist, R, Stamatopoulos, K, Stilgenbauer, S, Knight, S, Schuh, A, Oscier, D G, Strefford, J C

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Genome complexity in acute lymphoblastic leukemia is revealed by array-based comparative genomic hybridization von STREFFORD, J. C, WORLEY, H, GRIFFITHS, M, HING, S, ROSS, F. M, TALLEY, P, SAHA, V, MOORMAN, A. V, HARRISON, C. J, BARBER, K, WRIGHT, S, STEWART, A. R. M, ROBINSON, H. M, BETTNEY, G, VAN DELFT, F. W, ATHERTON, M. G, DAVIES, T

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The SF3B1 inhibitor spliceostatin A (SSA) elicits apoptosis in chronic lymphocytic leukaemia cells through downregulation of Mcl-1 von Larrayoz, M, Blakemore, S J, Dobson, R C, Blunt, M D, Rose-Zerilli, M J J, Walewska, R, Duncombe, A, Oscier, D, Koide, K, Forconi, F, Packham, G, Yoshida, M, Cragg, M S, Strefford, J C, Steele, A J

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Longitudinal copy number, whole exome and targeted deep sequencing of 'good risk' IGHV-mutated CLL patients with progressive disease von Rose-Zerilli, M J J, Gibson, J, Wang, J, Tapper, W, Davis, Z, Parker, H, Larrayoz, M, McCarthy, H, Walewska, R, Forster, J, Gardiner, A, Steele, A J, Chelala, C, Ennis, S, Collins, A, Oakes, C C, Oscier, D G, Strefford, J C

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Variant IRF4/MUM1 associates with CD38 status and treatment-free survival in chronic lymphocytic leukaemia von Allan, J M, Sunter, N J, Bailey, J R, Pettitt, A R, Harris, R J, Pepper, C, Fegan, C, Hall, A G, Deignan, L, Bacon, C M, Pointon, J C, Houlston, R S, Broderick, P, Mainou-Fowler, T, Jackson, G H, Summerfield, G, Evans, P A, Strefford, J C, Parker, A, Oscier, D, Pratt, G, Allsup, D J

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Lamin B1 regulates somatic mutations and progression of B-cell malignancies von Klymenko, T, Bloehdorn, J, Bahlo, J, Robrecht, S, Akylzhanova, G, Cox, K, Estenfelder, S, Wang, J, Edelmann, J, Strefford, J C, Wojdacz, T K, Fischer, K, Hallek, M, Stilgenbauer, S, Cragg, M, Gribben, J, Braun, A

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Non-coding NOTCH1 mutations in chronic lymphocytic leukemia; their clinical impact in the UK CLL4 trial von Larrayoz, M, Rose-Zerilli, M J J, Kadalayil, L, Parker, H, Blakemore, S, Forster, J, Davis, Z, Steele, A J, Collins, A, Else, M, Catovsky, D, Oscier, D G, Strefford, J C

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Derivative chromosome 9 deletions are a significant feature of childhood Philadelphia chromosome positive acute lymphoblastic leukaemia von ROBINSON, H. M, MARTINEAU, M, HARRIS, R. L, BARBER, K. E, JALALI, G. R, MOORMAN, A. V, STREFFORD, J. C, BROADFIELD, Z. J, CHEUNG, K. L, HARRISON, C. J

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P624: CHROMOTHRIPSIS IN PATIENTS WITH CLL AND COMPLEX KARYOTYPE: PATTERNS OF ABERRATIONS AND PROGNOSTIC VALUE von Ramos‐Campoy, S., Puiggros, A., Kamaso, J., Beà, S., Bougeon, S., Larráyoz, M. J., Costa, D., Parker, H., Rigolin, G. M., Blanco, M. L., Collado, R., Ancín, I., Salgado, R., Moro, M., Baumann, T., Gimeno, E., Moreno, C., Calasanz, M. J., Cuneo, A., Strefford, J. C., Nguyen‐Khac, F., Oscier, D., Haferlach, C., Schoumans, J., Espinet, B.

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Molecular characterisation of the t(1;15)(p22;q22) translocation in the prostate cancer cell line LNCaP von Strefford, J.C., Lane, T.M., Hill, A., LeRoux, L., Foot, N.J., Shipley, J., Oliver, R.T.D., Lu, Y.-J., Young, B.D.

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REFINING PROGNOSIS OF CHRONIC LYMPHOCYTIC LEUKEMIA WITH SOMATICALLY HYPERMUTATED B-CELL RECEPTORS: A NOVEL PROGNOSTIC INDEX ON BEHALF OF THE EUROPEAN RESEARCH INITIATIVE ON CLL (ER... von Baliakas, Panagiotis, Hadzidimitriou, A., Mattsson, Mattias, Xochelli, Aliki, Sutton, L. A., Minga, E., Scarfo, L., Rossi, D., Davis, Z., Agathangelidis, A., Villamor, N., Parker, H., Kotaskova, J., Stalika, E., Plevova, K., Mansouri, Larry, Cortese, Diego, Navarro Lopez, A., Delgado, J., Larrayoz, M., Anagnostopoulos, A., Belessi, C., Smedby, K. E., Juliusson, G., Strefford, J. C., Pospisilova, S., Oscier, D., Gaidano, G., Campo, E., Ghia, P., Rosenquist, Richard, Stamatopoulos, Kostas

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Comparative analysis of targeted next-generation sequencing panels for the detection of gene mutations in chronic lymphocytic leukemia: an ERIC multi-center study von Sutton, Lesley-Ann, Ljungstrom, Viktor, Enjuanes, Anna, Cortese, Diego, Skaftason, Aron, Tausch, Eugen, Kozubik, Katerina Stano, Nadeu, Ferran, Armand, Marine, Malcikova, Jikta, Pandzic, Tatjana, Forster, Jade, Davis, Zadie, Oscier, David, Rossi, Davide, Ghia, Paolo, Strefford, Jonathan C., Pospisilova, Sarka, Stilgenbauer, Stephan, Davi, Frederic, Campo, Elias, Stamatopoulos, Kostas, Rosenquist, Richard

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Overexpression of CEBPA resulting from the translocation t(14;19)(q32;q13) of human precursor B acute lymphoblastic leukemia von Chapiro, Elise, Russell, Lisa, Radford-Weiss, Isabelle, Bastard, Christian, Lessard, Michel, Struski, Stephanie, Cave, Helene, Fert-Ferrer, Sandra, Barin, Carole, Maarek, Odile, Della-Valle, Veronique, Strefford, Jonathan C., Berger, Roland, Harrison, Christine J., Bernard, Olivier A., Nguyen-Khac, Florence, the Groupe Francophone de Cytogénétique Hématologique

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High Surface IgM Levels Associate with Shorter Response Duration and Bypass of the BTK Blockade during Ibrutinib Therapy in CLL Patients von Chiodin, Giorgia, Dutton, David, Martino, Enrica Antonia, Drennan, Samantha, Tracy, Ian, Ondrisova, Laura, Henderson, Isla, D'Avola, Annalisa, Pitsillidou, Christina, Mraz, Marek, Johnson, Peter, Duncombe, Andrew, Packham, Graham, Steele, Andrew J, Parker, Helen, Bonfiglio, Silvia, Scarfo, Lydia, Sutton, Lesley-Ann, Ghia, Paolo, Rose-Zerilli, Matthew John Jerome, Strefford, Jonathan C, Stevenson, Freda K., Forconi, Francesco

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High surface IgM levels associate with shorter response to ibrutinib and BTK bypass in patients with CLL von Chiodin, Giorgia, Drennan, Samantha, Martino, Enrica A, Ondrisova, Laura, Henderson, Isla, Del Rio, Luis, Tracy, Ian, D'Avola, Annalisa, Parker, Helen, Bonfiglio, Silvia, Scarfò, Lydia, Sutton, Lesley-Ann, Strefford, Jonathan C, Forster, Jade, Brake, Oliver, Potter, Kathleen N, Sale, Benjamin, Lanham, Stuart, Mraz, Marek, Ghia, Paolo, Stevenson, Freda K, Forconi, Francesco

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Interphase molecular cytogenetic screening for chromosomal abnormalities of prognostic significance in childhood acute lymphoblastic leukaemia: a UK Cancer Cytogenetics Group Study von Harrison, Christine J., Moorman, Anthony V., Barber, Kerry E., Broadfield, Zoë J., Cheung, Kan L., Harris, Rachel L., Reza Jalali, G., Robinson, Hazel M., Strefford, Jonathan C., Stewart, Adam, Wright, Sarah, Griffiths, Mike, Ross, Fiona M., Harewood, Louise, Martineau, Mary

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EGR2 Mutations in Chronic Lymphocytic Leukemia: A New Bad Player von Noerenberg, Daniel, Young, Emma, Ljungström, Viktor, Mansouri, Larry, Plevova, Karla, Baliakas, Panagiotis, Blakemore, Stuart, Rossi, Davide, Clifford, Ruth, Navrkalova, Veronika, Sutton, Lesley-Ann, Smedby, Karin E, Juliusson, Gunnar, Belessi, Chrysoula, Panagiotidis, Panagiotis, Chiorazzi, Nicholas, Davi, Frederic, Langerak, Anton W., Schuh, Anna, Gaidano, Gianluca, Strefford, Jonathan C, Ghia, Paolo, Stamatopoulos, Kostas, Pospisilova, Sarka, Zenz, Thorsten, Rosenquist, Richard, Damm, Frederik

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