CXCR7 Antagonism Reduces Acute Lung Injury Pathogenesis von Pouzol, Laetitia, Sassi, Anna, Baumlin, Nadège, Tunis, Mélanie, Strasser, Daniel S., Lehembre, François, Martinic, Marianne M.

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Attenuation of murine sclerodermatous models by the selective S1P1 receptor modulator cenerimod von Kano, Miyu, Kobayashi, Tadahiro, Date, Mutsumi, Tennichi, Momoko, Hamaguchi, Yasuhito, Strasser, Daniel S, Takehara, Kazuhiko, Matsushita, Takashi

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Quantification of increased biologically active CXCL12α plasma concentrations after ACKR3 antagonist treatment in humans von Blattmann, Peter, Farine, Hervé, Dan, Brian, Stiffler, Nicole, Lefebvre, Thomas, Huynh, Christine, Sidharta, Patricia N., Dingemanse, Jasper, Welford, Richard W. D., Keller, Marcel, Strasser, Daniel S.

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Fragment-Based In Situ Combinatorial Approach To Identify High-Affinity Ligands for Unknown Binding Sites von Shelke, Sachin V, Cutting, Brian, Jiang, Xiaohua, Koliwer-Brandl, Hendrik, Strasser, Daniel S, Schwardt, Oliver, Kelm, Soerge, Ernst, Beat

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Plasma neurofilament light, glial fibrillary acidic protein and lysosphingolipid biomarkers for pharmacodynamics and disease monitoring of GM2 and GM1 gangliosidoses patients von Welford, Richard W.D., Farine, Herve, Steiner, Michel, Garzotti, Marco, Dobrenis, Kostantin, Sievers, Claudia, Strasser, Daniel S., Amraoui, Yasmina, Groenen, Peter M.A., Giugliani, Roberto, Mengel, Eugen

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Endothelin ETA Receptor Blockade, by Activating ETB Receptors, Increases Vascular Permeability and Induces Exaggerated Fluid Retention von Vercauteren, Magali, Trensz, Frederic, Pasquali, Anne, Cattaneo, Christophe, Strasser, Daniel S., Hess, Patrick, Iglarz, Marc, Clozel, Martine

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PHARMACOLOGICAL CHARACTERIZATION OF APROCITENTAN, A DUAL ENDOTHELIN RECEPTOR ANTAGONIST, ALONE AND IN COMBINATION WITH BLOCKERS OF THE RENIN ANGIOTENSIN SYSTEM, IN TWO MODELS OF EX... von Trensz, Frederic, Bortolamiol, Celine, Kramberg, Markus, Wanner, Daniel, Hadana, Hakim, Rey, Markus, Strasser, Daniel S, Delahaye, Stephane, Hess, Patrick, Vezzali, Enrico, Mentzel, Ulrich, Menard, Joel, Clozel, Martine, Iglarz, Marc

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Low Molecular Weight Antagonists of the Myelin-Associated Glycoprotein: Synthesis, Docking, and Biological Evaluation von Mesch, Stefanie, Moser, Delia, Strasser, Daniel S, Kelm, Antje, Cutting, Brian, Rossato, Gianluca, Vedani, Angelo, Koliwer-Brandl, Hendrik, Wittwer, Matthias, Rabbani, Said, Schwardt, Oliver, Kelm, Soerge, Ernst, Beat

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Monitoring inflammatory heterogeneity with multiple biomarkers for multidimensional endotyping of asthma von Agache, Ioana, Strasser, Daniel S., Pierlot, Gabin M., Farine, Hervé, Izuhara, Kenji, Akdis, Cezmi A.

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Combination treatment of a novel CXCR3 antagonist ACT-777991 with an anti-CD3 antibody synergistically increases persistent remission in experimental models of type 1 diabetes von Christen, Urs, Pouzol, Laetitia, Tunis, Mélanie, Sassi, Anna, Tondello, Camilla, Bayer, Monika, Hintermann, Edith, Strasser, Daniel S, Schuldes, Sabrina, Mentzel, Ulrich, Martinic, Marianne M

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ACKR3 Antagonism Enhances the Repair of Demyelinated Lesions Through Both Immunomodulatory and Remyelinating Effects von Pouzol, Laetitia, Sassi, Anna, Tunis, Mélanie, Zurbach, Anaïs, Baumlin, Nadège, Gnerre, Carmela, Strasser, Daniel S., Marrie, Julia, Vezzali, Enrico, Martinic, Marianne M.

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Pharmacokinetics, pharmacodynamics and safety of the novel C‐X‐C chemokine receptor 3 antagonist ACT‐777991: Results from the first‐in‐human study in healthy adults von Boof, Marie‐Laure, Géhin, Martine, Voors‐Pette, Christine, Hsin, Chih‐Hsuan, Sippel, Virginie, Strasser, Daniel S., Dingemanse, Jasper

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Biomarker‐guided clinical development of the first‐in‐class anti‐inflammatory FPR2/ALX agonist ACT‐389949 von Stalder, Anna K., Lott, Dominik, Strasser, Daniel S., Cruz, Hans G., Krause, Andreas, Groenen, Peter M.A., Dingemanse, Jasper

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Discovery of Clinical Candidate ACT-777991, a Potent CXCR3 Antagonist for Antigen-Driven and Inflammatory Pathologies von Meyer, Emmanuel A., Äänismaa, Päivi, Ertel, Eric A., Hühn, Eva, Strasser, Daniel S., Rey, Markus, Murphy, Mark J., Martinic, Marianne M., Pouzol, Laetitia, Froidevaux, Sylvie, Keller, Marcel P., Caroff, Eva

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Immunoaffinity Targeted Mass Spectrometry Analysis of Human Plasma Samples Reveals an Imbalance of Active and Inactive CXCL10 in Primary Sjögren's Syndrome Disease Patients von Schmidt, Alexander, Farine, Hervé, Keller, Marcel P, Sebastian, Agata, Kozera, Lukasz, Welford, Richard W D, Strasser, Daniel S

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Eosinophilic oesophagitis: relevance of mast cell infiltration von Strasser, Daniel S, Seger, Shanon, Bussmann, Christian, Pierlot, Gabin M, Groenen, Peter M A, Stalder, Anna K, Straumann, Alex

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Impact of high‐altitude therapy on type‐2 immune responses in asthma patients von Boonpiyathad, Tadech, Capova, Gertruda, Duchna, Hans‐Werner, Croxford, Andrew L., Farine, Herve, Dreher, Anita, Clozel, Martine, Schreiber, Juliane, Kubena, Petr, Lunjani, Nonhlanhla, Mirer, David, Rückert, Beate, Satitsuksanoa, Pattraporn, Tan, Ge, Groenen, Peter M. A., Bersuch, Eugen, Akdis, Mübeccel, Strasser, Daniel S., Renner, Ellen D., Akdis, Cezmi A.

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A Multipurpose First‐in‐Human Study With the Novel CXCR7 Antagonist ACT‐1004‐1239 Using CXCL12 Plasma Concentrations as Target Engagement Biomarker von Huynh, Christine, Henrich, Andrea, Strasser, Daniel S., Boof, Marie‐Laure, Al‐Ibrahim, Mohamed, Meyer Zu Schwabedissen, Henriette E., Dingemanse, Jasper, Ufer, Mike

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Genetic screening for Niemann-Pick disease type C in adults with neurological and psychiatric symptoms: findings from the ZOOM study von Bauer, Peter, Balding, David J, Klünemann, Hans H, Linden, David E J, Ory, Daniel S, Pineda, Mercè, Priller, Josef, Sedel, Frederic, Muller, Audrey, Chadha-Boreham, Harbajan, Welford, Richard W D, Strasser, Daniel S, Patterson, Marc C

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Modeling the Effect of the Selective S1P1 Receptor Modulator Ponesimod on Subsets of Blood Lymphocytes von Lott, Dominik, Krause, Andreas, Seemayer, Christian A., Strasser, Daniel S., Dingemanse, Jasper, Lehr, Thorsten

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