Sequential Orbitrap Secondary Ion Mass Spectrometry and Liquid Extraction Surface Analysis-Tandem Mass Spectrometry-Based Metabolomics for Prediction of Brain Tumor Relapse from Sa... von Meurs, Joris, Scurr, David J, Lourdusamy, Anbarasu, Storer, Lisa C.D, Grundy, Richard G, Alexander, Morgan R, Rahman, Ruman, Kim, Dong-Hyun

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Characterisation of Expression the Arginine Pathway Enzymes in Childhood Brain Tumours to Determine Susceptibility to Therapeutic Arginine Depletion von Bishop, Eleanor, Dimitrova, Monika, Froggatt, Alexander, Estevez-Cebrero, Maria, Storer, Lisa C. D., Mussai, Francis, Paine, Simon, Grundy, Richard G., Dandapani, Madhumita

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A retrospective analysis of recurrent pediatric ependymoma reveals extremely poor survival and ineffectiveness of current treatments across central nervous system locations and mol... von Ritzmann, Timothy A., Rogers, Hazel A., Paine, Simon M.L., Storer, Lisa C.D., Jacques, Thomas S., Chapman, Rebecca J., Ellison, David, Donson, Andrew M., Foreman, Nicholas K., Grundy, Richard G.

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Tissue metabolite profiles for the characterisation of paediatric cerebellar tumours von Bennett, Christopher D., Kohe, Sarah E., Gill, Simrandip K., Davies, Nigel P., Wilson, Martin, Storer, Lisa C. D., Ritzmann, Timothy, Paine, Simon M. L., Scott, Ian S., Nicklaus-Wollenteit, Ina, Tennant, Daniel A., Grundy, Richard G., Peet, Andrew C.

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A role for ABCB1 in prognosis, invasion and drug resistance in ependymoma von Sabnis, Durgagauri H., Storer, Lisa C. D., Liu, Jo-Fen, Jackson, Hannah K., Kilday, J. P., Grundy, Richard G., Kerr, Ian D., Coyle, Beth

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Overcoming multiple drug resistance mechanisms in medulloblastoma von Othman, Ramadhan T, Kimishi, Ioanna, Bradshaw, Tracey D, Storer, Lisa C D, Korshunov, Andrey, Pfister, Stefan M, Grundy, Richard G, Kerr, Ian D, Coyle, Beth

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Tumour compartment transcriptomics demonstrates the activation of inflammatory and odontogenic programmes in human adamantinomatous craniopharyngioma and identifies the MAPK/ERK pa... von Apps, John R., Carreno, Gabriela, Gonzalez-Meljem, Jose Mario, Haston, Scott, Guiho, Romain, Cooper, Julie E., Manshaei, Saba, Jani, Nital, Hölsken, Annett, Pettorini, Benedetta, Beynon, Robert J., Simpson, Deborah M., Fraser, Helen C., Hong, Ying, Hallang, Shirleen, Stone, Thomas J., Virasami, Alex, Donson, Andrew M., Jones, David, Aquilina, Kristian, Spoudeas, Helen, Joshi, Abhijit R., Grundy, Richard, Storer, Lisa C. D., Korbonits, Márta, Hilton, David A., Tossell, Kyoko, Thavaraj, Selvam, Ungless, Mark A., Gil, Jesus, Buslei, Rolf, Hankinson, Todd, Hargrave, Darren, Goding, Colin, Andoniadou, Cynthia L., Brogan, Paul, Jacques, Thomas S., Williams, Hywel J., Martinez-Barbera, Juan Pedro

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Modulating autophagy as a therapeutic strategy for the treatment of paediatric high‐grade glioma von Howarth, Alison, Madureira, Patricia A., Lockwood, George, Storer, Lisa C. D., Grundy, Richard, Rahman, Ruman, Pilkington, Geoffrey J., Hill, Richard

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Pediatric brain tumor cancer stem cells: cell cycle dynamics, DNA repair, and etoposide extrusion von Hussein, Deema, Punjaruk, Wiyada, Storer, Lisa C.D., Shaw, Lucy, Ottoman, Ramadan, Peet, Andrew, Miller, Suzanne, Bandopadhyay, Gagori, Heath, Rachel, Kumari, Rajendra, Bowman, Karen J., Braker, Paul, Rahman, Ruman, Jones, George D.D., Watson, Susan, Lowe, James, Kerr, Ian D., Grundy, Richard G., Coyle, Beth

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Integrative molecular characterization of pediatric spinal ependymoma: the UK Children’s Cancer and Leukaemia Group study von Ahmad, Omar, Chapman, Rebecca, Storer, Lisa C, Luo, Li, Heath, Paul R, Resar, Linda, Cohen, Kenneth J, Grundy, Richard G, Lourdusamy, Anbarasu

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Assessment of Cannabidiol and Δ9-Tetrahydrocannabiol in Mouse Models of Medulloblastoma and Ependymoma von Andradas, Clara, Byrne, Jacob, Kuchibhotla, Mani, Ancliffe, Mathew, Jones, Anya C, Carline, Brooke, Hii, Hilary, Truong, Alexandra, Storer, Lisa C D, Ritzmann, Timothy A, Grundy, Richard G, Gottardo, Nicholas G, Endersby, Raelene

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In search of effective therapies to overcome resistance to Temozolomide in brain tumours von Bouzinab, Kaouthar, Summers, Helen, Zhang, Jihong, Stevens, Malcolm F G, Moody, Christopher J, Turyanska, Lyudmila, Thomas, Neil R, Gershkovich, Pavel, Ashford, Marianne B, Vitterso, Emily, Storer, Lisa C D, Grundy, Richard, Bradshaw, Tracey D

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THER-04. IS THERE A ROLE FOR CANNABIDIOL IN THE TREATMENT OF CHILDHOOD BRAIN TUMOURS? von Lockwood, George, Hatfield, Amelia, Mabrouk, Mohamed, O’Sullivan, Saoirse E, Grundy, Richard G, Storer, Lisa C D

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THER-03. IN VITRO EVALUATION OF THE EFFECT OF CANNABIDIOL ON PAEDIATRIC BRAIN TUMOUR CELL LINES USING A PULSED TREATMENT REGIME von Faulkes, Sophie, Lockwood, George, O’Sullivan, Saoirse E, Grundy, Richard G, Storer, Lisa C D

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MBRS-20. KETOLYTIC AND GLYCOLYTIC ENZYMATIC EXPRESSION IN PAEDIATRIC MEDULLOBLASTOMAS: IMPLICATION FOR KETOGENIC DIET THERAPY von Storer, Lisa C D, de Beer, Zacharias, Lockwood, George, Paine, Simon, Grundy, Richard G

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EPEN-24. SIOP EPENDYMOMA II: CENTRAL EPENDYMOMA MANAGEMENT ADVISORY GROUP – THE UK EXPERIENCE von Macarthur, Donald C, Mallucci, Conor, Kamaly-Asl, Ian, Goodden, John, Storer, Lisa C D, Chapman, Rebecca J, Kilday, J-P, English, Martin, Jaspan, Tim, Chattopadhyay, Arpita, Dineen, Rob A, Avula, Shivaram, Stivaros, Stavros, Grundy, Richard

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Abstract LB-224: A novel model of pediatric spinal ependymoma using conditionally reprogrammed cells from a primary tumor demonstrates aberrant expression of HMGA, HOX, MYC and oth... von Luo, Li Z., Krawczyk, Ewa, Lourdusamy, Anbarasu, Storer, Lisa C., Xian, Lingling, Cohen, Kenneth J., Schlegel, Richard, Grundy, Richard, Resar, Linda

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Transcriptomic analysis in pediatric spinal ependymoma reveals distinct molecular signatures von Lourdusamy, Anbarasu, Luo, Li Z, Storer, Lisa Cd, Cohen, Kenneth J, Resar, Linda, Grundy, Richard G

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MBRS-29. IN-VIVO METABOLITE PROFILES FOR THE NON-INVASIVE AND RAPID IDENTIFICATION OF MOLECULAR SUBGROUP IN MEDULLOBLASTOMA von Kohe, Sarah E, Babourina-Brooks, Ben, Scerif, Fatma, Hicks, Debbie, Schwalbe, Ed C, Crosier, Stephen, Lindsey, Janet, Adiamah, Magretta, Storer, Lisa C D, Lourdusamy, Anbarasu, Gill, Simrandip K, Bennett, Christopher D, Wilson, Martin, Avula, Shivaram, Mitra, Dipayan, Dineen, Rob, Bailey, Simon, Williamson, Daniel, Grundy, Richard G, Clifford, Steven C, Peet, Andrew C

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TBIO-09. IN VITRO EVALUATION OF THE POTENTIAL OF GLUCOSE RESTRICTION AS AN ADJUVANT THERAPY FOR PAEDIATRIC BRAIN TUMOURS von Lockwood, George, Apte, Janhavi, Ivanov, Delyan, Parr, Rebecca, Walker, David A, Storer, Lisa CD, Grundy, Richard G

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