Clinical Pharmacokinetics and Pharmacodynamics of Afatinib von Wind, Sven, Schnell, David, Ebner, Thomas, Freiwald, Matthias, Stopfer, Peter

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Clinical Pharmacokinetics and Pharmacodynamics of Nintedanib von Wind, Sven, Schmid, Ulrike, Freiwald, Matthias, Marzin, Kristell, Lotz, Ralf, Ebner, Thomas, Stopfer, Peter, Dallinger, Claudia

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Phase I Trial of the Irreversible EGFR and HER2 Kinase Inhibitor BIBW 2992 in Patients With Advanced Solid Tumors von YAP, Timothy A, VIDAL, Laura, UTTENREUTHER-FISCHER, Martina, STOPFER, Peter, FUTREAL, Andrew, CALVERT, Hilary, DE BONO, Johann S, PLUMMER, Ruth, ADAM, Jan, STEPHENS, Peter, SPICER, James, SHAW, Heather, ANG, Jooern, TEMPLE, Graham, BELL, Susan, SHAHIDI, Mehdi

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Validation of a Drug Transporter Probe Cocktail Using the Prototypical Inhibitors Rifampin, Probenecid, Verapamil, and Cimetidine von Wiebe, Sabrina T., Giessmann, Thomas, Hohl, Kathrin, Schmidt-Gerets, Sven, Hauel, Edith, Jambrecina, Alen, Bader, Kerstin, Ishiguro, Naoki, Taub, Mitchell E., Sharma, Ashish, Ebner, Thomas, Mikus, Gerd, Fromm, Martin F., Müller, Fabian, Stopfer, Peter

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Optimization of a drug transporter probe cocktail: potential screening tool for transporter‐mediated drug–drug interactions von Stopfer, Peter, Giessmann, Thomas, Hohl, Kathrin, Hutzel, Sabine, Schmidt, Sven, Gansser, Dietmar, Ishiguro, Naoki, Taub, Mitchell E., Sharma, Ashish, Ebner, Thomas, Müller, Fabian

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Afatinib pharmacokinetics and metabolism after oral administration to healthy male volunteers von Stopfer, Peter, Marzin, Kristell, Narjes, Hans, Gansser, Dietmar, Shahidi, Mehdi, Uttereuther-Fischer, Martina, Ebner, Thomas

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Phase I Study of the Angiogenesis Inhibitor BIBF 1120 in Patients with Advanced Solid Tumors von MROSS, Klaus, STEFANIC, Martin, DE ROSSI, Lothar, KAISER, Rolf, GMEHLING, Daniela, FROST, Annette, BAAS, Franziska, UNGER, Clemens, STRECKER, Ralph, HENNING, Jürgen, GASCHLER-MARKEFSKI, Birgit, STOPFER, Peter

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A Mechanistic, Enantioselective, Physiologically Based Pharmacokinetic Model of Verapamil and Norverapamil, Built and Evaluated for Drug-Drug Interaction Studies von Hanke, Nina, Tuerk, Denise, Selzer, Dominik, Wiebe, Sabrina, Fernandez, Eric, Stopfer, Peter, Nock, Valerie, Lehr, Thorsten

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Randomized phase II study of nintedanib in metastatic castration-resistant prostate cancer postdocetaxel von Droz, Jean-Pierre, Medioni, Jaques, Chevreau, Christine, De Mont-Serrat, Helene, Merger, Michael, Stopfer, Peter, Kaiser, Rolf, Oudard, Stephane

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An Open-label Dose-escalation Study of BIBF 1120 in Patients with Relapsed or Refractory Multiple Myeloma von KROPFF, Martin, KIENAST, Joachim, LISPING, Guido, BERDEL, Wolfgang E, GASCHLER-MARKEFSKI, Birgit, STOPFER, Peter, STEFANIC, Martin, MUNZERT, Gerd

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Beyond CL and VSS: A comprehensive approach to human pharmacokinetic predictions von Himstedt, Anneke, Rapp, Hermann, Stopfer, Peter, Lotz, Ralf, Scheuerer, Stefan, Arnhold, Thomas, Sauer, Achim, Borghardt, Jens Markus

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Pharmacokinetics of Afatinib, a Selective Irreversible ErbB Family Blocker, in Patients with Advanced Solid Tumours von Wind, Sven, Schmid, Marion, Erhardt, Julia, Goeldner, Rainer-Georg, Stopfer, Peter

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A Comprehensive Whole-Body Physiologically Based Pharmacokinetic Drug–Drug–Gene Interaction Model of Metformin and Cimetidine in Healthy Adults and Renally Impaired Individuals von Hanke, Nina, Türk, Denise, Selzer, Dominik, Ishiguro, Naoki, Ebner, Thomas, Wiebe, Sabrina, Müller, Fabian, Stopfer, Peter, Nock, Valerie, Lehr, Thorsten

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Physiologically Based Pharmacokinetic Modeling of Rosuvastatin to Predict Transporter-Mediated Drug-Drug Interactions von Hanke, Nina, Gómez-Mantilla, José David, Ishiguro, Naoki, Stopfer, Peter, Nock, Valerie

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Pharmacokinetic Properties of Nintedanib in Healthy Volunteers and Patients With Advanced Cancer von Dallinger, Claudia, Trommeshauser, Dirk, Marzin, Kristell, Liesener, Andre, Kaiser, Rolf, Stopfer, Peter

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New Biomarkers for Renal Transporter-Mediated Drug-Drug Interactions: Metabolomic Effects of Cimetidine, Probenecid, Verapamil, and Rifampin in Humans von Gessner, Arne, König, Jörg, Wenisch, Pia, Heinrich, Markus R, Stopfer, Peter, Fromm, Martin F, Müller, Fabian

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Physiologically Based Pharmacokinetic Models of Probenecid and Furosemide to Predict Transporter Mediated Drug-Drug Interactions von Britz, Hannah, Hanke, Nina, Taub, Mitchell E., Wang, Ting, Prasad, Bhagwat, Fernandez, Éric, Stopfer, Peter, Nock, Valerie, Lehr, Thorsten

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N1‐Methylnicotinamide as Biomarker for MATE‐Mediated Renal Drug–Drug Interactions: Impact of Cimetidine, Rifampin, Verapamil, and Probenecid von Müller, Fabian, Hohl, Kathrin, Keller, Sascha, Schmidt‐Gerets, Sven, Deutsch, Birgit, Schuler‐Metz, Annette, Fromm, Martin F., Stopfer, Peter, Gessner, Arne

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A Metabolomic Analysis of Sensitivity and Specificity of 23 Previously Proposed Biomarkers for Renal Transporter‐Mediated Drug‐Drug Interactions von Gessner, Arne, Müller, Fabian, Wenisch, Pia, Heinrich, Markus R., König, Jörg, Stopfer, Peter, Fromm, Martin F.

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Phase I Open-Label Study of Continuous Treatment with BIBF 1120, a Triple Angiokinase Inhibitor, and Pemetrexed in Pretreated Non-Small Cell Lung Cancer Patients von ELLIS, Peter M, KAISER, Rolf, YIHUA ZHAO, STOPFER, Peter, GYORFFY, Steve, HANNA, Nasser

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