A coiled-coil masking domain for selective activation of therapeutic antibodies von Trang, Vivian H., Zhang, Xinqun, Yumul, Roma C., Zeng, Weiping, Stone, Ivan J., Wo, Serena W., Dominguez, Melissa M., Cochran, Julia H., Simmons, Jessica K., Ryan, Maureen C., Lyon, Robert P., Senter, Peter D., Levengood, Matthew R.

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Optimization of a PEGylated Glucuronide-Monomethylauristatin E Linker for Antibody-Drug Conjugates von Burke, Patrick J, Hamilton, Joseph Z, Jeffrey, Scott C, Hunter, Joshua H, Doronina, Svetlana O, Okeley, Nicole M, Miyamoto, Jamie B, Anderson, Martha E, Stone, Ivan J, Ulrich, Michelle L, Simmons, Jessica K, McKinney, Erica E, Senter, Peter D, Lyon, Robert P

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Development of Novel Quaternary Ammonium Linkers for Antibody-Drug Conjugates von Burke, Patrick J, Hamilton, Joseph Z, Pires, Thomas A, Setter, Jocelyn R, Hunter, Joshua H, Cochran, Julia H, Waight, Andrew B, Gordon, Kristine A, Toki, Brian E, Emmerton, Kim K, Zeng, Weiping, Stone, Ivan J, Senter, Peter D, Lyon, Robert P, Jeffrey, Scott C

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Potent Anticarcinoma Activity of the Humanized Anti-CD70 Antibody h1F6 Conjugated to the Tubulin Inhibitor Auristatin via an Uncleavable Linker von OFLAZOGLU, Ezogelin, STONE, Ivan J, GORDON, Kristine, WOOD, Christopher G, REPASKY, Elizabeth A, GREWAL, Iqbal S, LAW, Che-Leung, GERBERA, Hans-Peter

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Macrophages contribute to the antitumor activity of the anti-CD30 antibody SGN-30 von Oflazoglu, Ezogelin, Stone, Ivan J., Gordon, Kristine A., Grewal, Iqbal S., van Rooijen, Nico, Law, Che-Leung, Gerber, Hans-Peter

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A Potent Anti-CD70 Antibody–Drug Conjugate Combining a Dimeric Pyrrolobenzodiazepine Drug with Site-Specific Conjugation Technology von Jeffrey, Scott C, Burke, Patrick J, Lyon, Robert P, Meyer, David W, Sussman, Django, Anderson, Martha, Hunter, Joshua H, Leiske, Chris I, Miyamoto, Jamie B, Nicholas, Nicole D, Okeley, Nicole M, Sanderson, Russell J, Stone, Ivan J, Zeng, Weiping, Gregson, Stephen J, Masterson, Luke, Tiberghien, Arnaud C, Howard, Philip W, Thurston, David E, Law, Che-Leung, Senter, Peter D

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Tumor-Associated Macrophages Can Contribute to Antitumor Activity through FcγR-Mediated Processing of Antibody-Drug Conjugates von Li, Fu, Ulrich, Michelle, Jonas, Mechthild, Stone, Ivan J, Linares, Germein, Zhang, Xinqun, Westendorf, Lori, Benjamin, Dennis R, Law, Che-Leung

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SGN-CD228A Is an Investigational CD228-Directed Antibody-Drug Conjugate with Potent Antitumor Activity across a Wide Spectrum of Preclinical Solid Tumor Models von Mazahreh, Rebecca, Mason, Marsha L, Gosink, John J, Olson, Devra J, Thurman, Robert, Hale, Christopher, Westendorf, Lori, Pires, Thomas A, Leiske, Christopher I, Carlson, Markus, Nguyen, Liem T, Cochran, Julia H, Okeley, Nicole M, Yumul, Roma, Jin, Steven, Stone, Ivan J, Sahetya, Disha, Nesterova, Albina, Allred, Sean, Hensley, Kelly M, Hu, Rachael, Lawrence, Robert, Lewis, Timothy S, Sandall, Sharsti

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Improving Antibody‐Tubulysin Conjugates through Linker Chemistry and Site‐Specific Conjugation von Hamilton, Joseph Z., Pires, Thomas A., Mitchell, Jamie A., Cochran, Julia H., Emmerton, Kim K., Zaval, Margo, Stone, Ivan J., Anderson, Martha E., Jin, Steven, Waight, Andrew B., Lyon, Robert P., Senter, Peter D., Jeffrey, Scott C., Burke, Patrick J.

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Development and Properties of β-Glucuronide Linkers for Monoclonal Antibody−Drug Conjugates von Jeffrey, Scott C, Andreyka, Jamie B, Bernhardt, Starr X, Kissler, Kim M, Kline, Toni, Lenox, Joel S, Moser, Ruth F, Nguyen, Minh T, Okeley, Nicole M, Stone, Ivan J, Zhang, Xinqun, Senter, Peter D

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Characterization of SGN-CD123A, A Potent CD123-Directed Antibody-Drug Conjugate for Acute Myeloid Leukemia von Li, Fu, Sutherland, May Kung, Yu, Changpu, Walter, Roland B, Westendorf, Lori, Valliere-Douglass, John, Pan, Lucy, Cronkite, Ashley, Sussman, Django, Klussman, Kerry, Ulrich, Michelle, Anderson, Martha E, Stone, Ivan J, Zeng, Weiping, Jonas, Mechthild, Lewis, Timothy S, Goswami, Maitrayee, Wang, Sa A, Senter, Peter D, Law, Che-Leung, Feldman, Eric J, Benjamin, Dennis R

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Effects of Dehydroepiandrosterone Sulfate and Progesterone on Spatial Learning and Memory in Young and Aged Mice von Bodensteiner, Karin J., Stone, Ivan J., Ghiraldi, Loraina L.

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Abstract 1339: Preclinical combination activity of SGN-CD19A and CVAD in patient-derived B-lineage acute lymphoblastic leukemia models von Stone, Ivan J., Albertson, Tina, Law, Che-Leung

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Abstract 750: Modular coiled-coil masking domains for tumor-specific antibody activation von Trang, Vivian H., Zhang, Xinqun, Dominguez, Melissa M., Zeng, Weiping, Cochran, Julia H., Stone, Ivan J., Senter, Peter D., Levengood, Matthew R.

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Front Cover: Improving Antibody‐Tubulysin Conjugates through Linker Chemistry and Site‐Specific Conjugation (ChemMedChem 7/2021) von Hamilton, Joseph Z., Pires, Thomas A., Mitchell, Jamie A., Cochran, Julia H., Emmerton, Kim K., Zaval, Margo, Stone, Ivan J., Anderson, Martha E., Jin, Steven, Waight, Andrew B., Lyon, Robert P., Senter, Peter D., Jeffrey, Scott C., Burke, Patrick J.

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Abstract 2647: SGN-CD70A, a novel and highly potent anti-CD70 ADC, induces double-strand DNA breaks and is active in models of MDR+ renal cell carcinoma (RCC) and non-Hodgkin lymph... von Sandall, Sharsti, Anderson, Martha, Jonas, Mechthild, Nesterova, Albina, Miyamoto, Jamie, Stone, Ivan J., Zeng, Weiping, Law, Che-Leung, Lewis, Timothy S.

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Preclinical Analysis of the Combined Activity of SGN-40, Anti-CD40 Monoclonal Antibody, with Rituximab in Non-Hodgkin Lymphoma von Lewis, Timothy S., McCormick, Renee S., McEarchern, Julie A., Kissler, Kim, Stone, Ivan J., Gerber, Hans-Peter, Drachman, Jonathan G., Grewal, Iqbal, Law, Che-Leung

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Constitutively active STAT6 predisposes toward a lymphoproliferative disorder von Kaplan, Mark H., Sehra, Sarita, Chang, Hua-Chen, O'Malley, John T., Mathur, Anubhav N., Bruns, Heather A.

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The Humanized Anti-CD40 Monoclonal Antibody, SGN-40, Potentiates Chemotherapy Regimens in NHL Xenograft Models Via Pro-Apoptotic Signaling von Lewis, Timothy S., McCormick, Renee S., Kissler, Kim, Stone, Ivan J., Jonas, Mechthild, Sutherland, May S.K., Gerber, Hans-Peter, Drachman, Jonathan G., Grewal, Iqbal S., Law, Che-Leung

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SEMICONDUCTOR WAFER FRONT SIDE PROTECTION von KRYWANCZYK TIMOTHY C, ABRAMS ALLAN D, BROUILLETTE DONALD W, DANAHER JOSEPH D, STONE IVAN J, WHALEN MATTHEW R, LAMOTHE RENE A

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