A Deep Learning Approach to Antibiotic Discovery von Stokes, Jonathan M., Yang, Kevin, Swanson, Kyle, Jin, Wengong, Cubillos-Ruiz, Andres, Donghia, Nina M., MacNair, Craig R., French, Shawn, Carfrae, Lindsey A., Bloom-Ackermann, Zohar, Tran, Victoria M., Chiappino-Pepe, Anush, Badran, Ahmed H., Andrews, Ian W., Chory, Emma J., Church, George M., Brown, Eric D., Jaakkola, Tommi S., Barzilay, Regina, Collins, James J.

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Overcoming mcr-1 mediated colistin resistance with colistin in combination with other antibiotics von MacNair, Craig R., Stokes, Jonathan M., Carfrae, Lindsey A., Fiebig-Comyn, Aline A., Coombes, Brian K., Mulvey, Michael R., Brown, Eric D.

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Cytoplasmic condensation induced by membrane damage is associated with antibiotic lethality von Wong, Felix, Stokes, Jonathan M., Cervantes, Bernardo, Penkov, Sider, Friedrichs, Jens, Renner, Lars D., Collins, James J.

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Cold Stress Makes Escherichia coli Susceptible to Glycopeptide Antibiotics by Altering Outer Membrane Integrity von Stokes, Jonathan M., French, Shawn, Ovchinnikova, Olga G., Bouwman, Catrien, Whitfield, Chris, Brown, Eric D.

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A Deep Learning Approach to Antibiotic Discovery von Stokes, Jonathan M., Yang, Kevin, Swanson, Kyle, Jin, Wengong, Cubillos-Ruiz, Andres, Donghia, Nina M., MacNair, Craig R., French, Shawn, Carfrae, Lindsey A., Bloom-Ackermann, Zohar, Tran, Victoria M., Chiappino-Pepe, Anush, Badran, Ahmed H., Andrews, Ian W., Chory, Emma J., Church, George M., Brown, Eric D., Jaakkola, Tommi S., Barzilay, Regina, Collins, James J.

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Pentamidine sensitizes Gram-negative pathogens to antibiotics and overcomes acquired colistin resistance von Stokes, Jonathan M., MacNair, Craig R., Ilyas, Bushra, French, Shawn, Côté, Jean-Philippe, Bouwman, Catrien, Farha, Maya A., Sieron, Arthur O., Whitfield, Chris, Coombes, Brian K., Brown, Eric D.

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Bacterial Metabolism and Antibiotic Efficacy von Stokes, Jonathan M., Lopatkin, Allison J., Lobritz, Michael A., Collins, James J.

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Our Evolving Understanding of the Mechanism of Quinolones von Gutierrez, Arnaud, Stokes, Jonathan M, Matic, Ivan

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Antibiotic discovery in the artificial intelligence era von Lluka, Telmah, Stokes, Jonathan M.

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Discovery of a small molecule that inhibits bacterial ribosome biogenesis von Stokes, Jonathan M, Davis, Joseph H, Mangat, Chand S, Williamson, James R, Brown, Eric D

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Eradicating Bacterial Persisters with Combinations of Strongly and Weakly Metabolism-Dependent Antibiotics von Zheng, Erica J., Stokes, Jonathan M., Collins, James J.

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Machine learning in preclinical drug discovery von Catacutan, Denise B., Alexander, Jeremie, Arnold, Autumn, Stokes, Jonathan M.

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Clinically relevant mutations in core metabolic genes confer antibiotic resistance von Lopatkin, Allison J, Bening, Sarah C, Manson, Abigail L, Stokes, Jonathan M, Kohanski, Michael A, Badran, Ahmed H, Earl, Ashlee M, Cheney, Nicole J, Yang, Jason H, Collins, James J

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Deep learning identifies synergistic drug combinations for treating COVID-19 von Jin, Wengong, Stokes, Jonathan M., Eastman, Richard T., Itkin, Zina, Zakharov, Alexey V., Collins, James J., Jaakkola, Tommi S., Barzilay, Regina

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Deep learning-guided discovery of an antibiotic targeting Acinetobacter baumannii von Liu, Gary, Catacutan, Denise B., Rathod, Khushi, Swanson, Kyle, Jin, Wengong, Mohammed, Jody C., Chiappino-Pepe, Anush, Syed, Saad A., Fragis, Meghan, Rachwalski, Kenneth, Magolan, Jakob, Surette, Michael G., Coombes, Brian K., Jaakkola, Tommi, Barzilay, Regina, Collins, James J., Stokes, Jonathan M.

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Discovery of a structural class of antibiotics with explainable deep learning von Wong, Felix, Zheng, Erica J., Valeri, Jacqueline A., Donghia, Nina M., Anahtar, Melis N., Omori, Satotaka, Li, Alicia, Cubillos-Ruiz, Andres, Krishnan, Aarti, Jin, Wengong, Manson, Abigail L., Friedrichs, Jens, Helbig, Ralf, Hajian, Behnoush, Fiejtek, Dawid K., Wagner, Florence F., Soutter, Holly H., Earl, Ashlee M., Stokes, Jonathan M., Renner, Lars D., Collins, James J.

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Reactive metabolic byproducts contribute to antibiotic lethality under anaerobic conditions von Wong, Felix, Stokes, Jonathan M., Bening, Sarah C., Vidoudez, Charles, Trauger, Sunia A., Collins, James J.

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Bacterial metabolic state more accurately predicts antibiotic lethality than growth rate von Lopatkin, Allison J., Stokes, Jonathan M., Zheng, Erica J., Yang, Jason H., Takahashi, Melissa K., You, Lingchong, Collins, James J.

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Bicarbonate Alters Bacterial Susceptibility to Antibiotics by Targeting the Proton Motive Force von Farha, Maya A, French, Shawn, Stokes, Jonathan M, Brown, Eric D

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Generative AI for designing and validating easily synthesizable and structurally novel antibiotics von Swanson, Kyle, Liu, Gary, Catacutan, Denise B., Arnold, Autumn, Zou, James, Stokes, Jonathan M.

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